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Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise

Yang Rongze ; Wang Xuewen ; Disanzo Beth L ; You Tongjian ; Gong Dawei

Lipids in health and disease, 01 October 2011, Vol.10(1), p.194 [Peer Reviewed Journal]

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Increasing endogenous 2‐arachidonoylglycerol levels counteracts colitis and related systemic inflammation

Alhouayek, Mireille ; Lambert, Didier M. ; Delzenne, Nathalie M. ; Cani, Patrice D. ; Muccioli, Giulio G.

FASEB Journal, August 2011, Vol.25(8), pp.2711-2721 [Peer Reviewed Journal]

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α-Ketoheterocycle inhibitors of fatty acid amide hydrolase: Exploration of conformational constraints in the acyl side chain

Duncan, Katharine K ; Otrubova, Katerina ; Boger, Dale L

Bioorganic & Medicinal Chemistry, 01 May 2014, Vol.22(9), pp.2763-2770 [Peer Reviewed Journal]

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Cannabinoid receptor type 1 immunoreactivity and disease severity in human epithelial ovarian tumors

Messalli, Enrico Michelino ; Grauso, Flavio ; Luise, Rossella ; Angelini, Anna ; Rossiello, Raffaele

American Journal of Obstetrics and Gynecology, September 2014, Vol.211(3), pp.234.e1-234.e6 [Peer Reviewed Journal]

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FAAH Gene Variation Moderates Stress Response and Symptom Severity in Patients with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence

Spagnolo, Primavera A. ; Ramchandani, Vijay A. ; Schwandt, Melanie L. ; Kwako, Laura E. ; George, David T. ; Mayo, Leah M. ; Hillard, Cecilia J. ; Heilig, Markus

Alcoholism: Clinical and Experimental Research, November 2016, Vol.40(11), pp.2426-2434 [Peer Reviewed Journal]

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Brain region‐specific changes in N ‐acylethanolamine contents with time of day

Liedhegner, Elizabeth Sabens ; Sasman, Amy ; Hillard, Cecilia J.

Journal of Neurochemistry, February 2014, Vol.128(4), pp.491-506 [Peer Reviewed Journal]

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Fatty Acid Amide Hydrolase Binding in Brain of Cannabis Users: Imaging With the Novel Radiotracer [11C]CURB

Boileau, Isabelle ; Mansouri, Esmaeil ; Williams, Belinda ; Le Foll, Bernard ; Rusjan, Pablo ; Mizrahi, Romina ; Tyndale, Rachel F ; Huestis, Marilyn A ; Payer, Doris E ; Wilson, Alan A ; Houle, Sylvain ; Kish, Stephen J ; Tong, Junchao

Biological Psychiatry, 01 November 2016, Vol.80(9), pp.691-701 [Peer Reviewed Journal]

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Effects of synthetic alkamides on Arabidopsis fatty acid amide hydrolase activity and plant development

Faure, Lionel ; Cavazos, Ronaldo ; Khan, Bibi Rafeiza ; Petros, Robby A ; Koulen, Peter ; Blancaflor, Elison B ; Chapman, Kent D

Phytochemistry, February 2015, Vol.110, pp.58-71 [Peer Reviewed Journal]

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Elevation of 2-AG by Monoacylglycerol Lipase Inhibition in the Visceral Insular Cortex Interferes With Anticipatory Nausea in a Rat Model

Limebeer, Cheryl L. ; Rock, Erin M. ; Puvanenthirarajah, Nirushan ; Niphakis, Micah J. ; Cravatt, Benjamin F. ; Parker, Linda A.

Behavioral Neuroscience, 2016, Vol.130(2), pp.261-266 [Peer Reviewed Journal]

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Inhibition of fatty acid amide hydrolase suppresses referred hyperalgesia induced by bladder inflammation

Merriam, Fabiola Voznika ; Wang, Zun‐Yi ; Hillard, Cecilia J. ; Stuhr, Kara L. ; Bjorling, Dale E.

BJU International, October 2011, Vol.108(7), pp.1145-1149 [Peer Reviewed Journal]

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Early exposure to environmental enrichment alters the expression of genes of the endocannabinoid system

El Rawas, Rana ; Thiriet, Nathalie ; Nader, Joëlle ; Lardeux, Virginie ; Jaber, Mohamed ; Solinas, Marcello

Brain Research, 2011, Vol.1390, pp.80-89 [Peer Reviewed Journal]

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Anti-aversive role of the endocannabinoid system in the periaqueductal gray stimulation model of panic attacks in rats

Viana, Thércia ; Hott, Sara ; Resstel, Leonardo ; Aguiar, Daniele ; Moreira, Fabrício

Psychopharmacology, 2015, Vol.232(9), pp.1545-1553 [Peer Reviewed Journal]

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Effect of footshock stress on place conditioning produced by Δ 9 -tetrahydrocannabinol and the fatty acid amide hydrolase (FAAH) inhibitor, URB597, in Sprague-Dawley rats

DeVuono, Marieka ; Wills, Kiri ; MacPherson, Danielle ; Hrelja, Kelly ; Parker, Linda

Psychopharmacology, 2017, Vol.234(21), pp.3229-3240 [Peer Reviewed Journal]

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Involvement of Endocannabinoids in Alcohol “Binge” Drinking: Studies of Mice with Human Fatty Acid Amide Hydrolase Genetic Variation and After CB1 Receptor Antagonists

Zhou, Yan ; Huang, Ted ; Lee, Francis ; Kreek, Mary Jeanne

Alcoholism: Clinical and Experimental Research, March 2016, Vol.40(3), pp.467-473 [Peer Reviewed Journal]

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Activation of cannabinoid receptor 1 inhibits increased bladder activity induced by nerve growth factor

Wang, Zun-Yi ; Wang, Peiqing ; Bjorling, Dale E

Neuroscience Letters, 04 March 2015, Vol.589, pp.19-24 [Peer Reviewed Journal]

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Contributions of endocannabinoid signaling to psychiatric disorders in humans: genetic and biochemical evidence

Hillard, C.J ; Weinlander, K.M ; Stuhr, K.L

Neuroscience, 01 March 2012, Vol.204, pp.207-229 [Peer Reviewed Journal]

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17
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Development and characterization of endocannabinoid hydrolases FAAH and MAGL inhibitors bearing a benzotriazol-1-yl carboxamide scaffold

Morera, Ludovica ; Labar, Geoffray ; Ortar, Giorgio ; Lambert, Didier M

Bioorganic & Medicinal Chemistry, 01 November 2012, Vol.20(21), pp.6260-6275 [Peer Reviewed Journal]

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18
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Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL)

Korhonen, Jani ; Kuusisto, Anne ; van Bruchem, John ; Patel, Jayendra Z ; Laitinen, Tuomo ; Navia-Paldanius, Dina ; Laitinen, Jarmo T ; Savinainen, Juha R ; Parkkari, Teija ; Nevalainen, Tapio J

Bioorganic & Medicinal Chemistry, 01 December 2014, Vol.22(23), pp.6694-6705 [Peer Reviewed Journal]

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19
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Design, synthesis and evaluation of polar head group containing 2-keto-oxazole inhibitors of FAAH

Rusch, Marion ; Zahov, Stefan ; Vetter, Ingrid R ; Lehr, Matthias ; Hedberg, Christian

Bioorganic & Medicinal Chemistry, 15 January 2012, Vol.20(2), pp.1100-1112 [Peer Reviewed Journal]

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20
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N-(3,4-Dimethylisoxazol-5-yl)piperazine-4-[4-(2-fluoro-4-[11C]methylphenyl)thiazol-2-yl]-1-carboxamide: A promising positron emission tomography ligand for fatty acid amide hydrolase

Shimoda, Yoko ; Fujinaga, Masayuki ; Hatori, Akiko ; Yui, Joji ; Zhang, Yiding ; Nengaki, Nobuki ; Kurihara, Yusuke ; Yamasaki, Tomoteru ; Xie, Lin ; Kumata, Katsushi ; Ishii, Hideki ; Zhang, Ming-Rong

Bioorganic & Medicinal Chemistry, 15 February 2016, Vol.24(4), pp.627-634 [Peer Reviewed Journal]

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21
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1-Heteroarylpropan-2-ones as inhibitors of fatty acid amide hydrolase: Studies on structure-activity relationships and metabolic stability

Zahov, Stefan ; Garzinsky, David ; Hanekamp, Walburga ; Lehr, Matthias

Bioorganic & Medicinal Chemistry, 01 February 2017, Vol.25(3), pp.825-837 [Peer Reviewed Journal]

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22
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Involvement of the opioid and cannabinoid systems in pain control: New insights from knockout studies

Nadal, Xavier ; La Porta, Carmen ; Andreea Bura, S ; Maldonado, Rafael

European Journal of Pharmacology, 15 September 2013, Vol.716(1-3), pp.142-157 [Peer Reviewed Journal]

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23
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Inhibition of fatty acid amide hydrolase and cyclooxygenase by the N-(3-methylpyridin-2-yl)amide derivatives of flurbiprofen and naproxen

Cipriano, Mariateresa ; Björklund, Emmelie ; Wilson, Alan A ; Congiu, Cenzo ; Onnis, Valentina ; Fowler, Christopher J

European Journal of Pharmacology, 15 November 2013, Vol.720(1-3), pp.383-390 [Peer Reviewed Journal]

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24
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The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆9-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice

Walentiny, D. Matthew ; Gamage, Thomas F ; Warner, Jonathan A ; Nguyen, Thanh K ; Grainger, Darren B ; Wiley, Jenny L ; Vann, Robert E

European Journal of Pharmacology, 10 April 2011, Vol.656(1-3), pp.63-67 [Peer Reviewed Journal]

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25
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Biochemical characterization and in vitro activity of AZ513, a noncovalent, reversible, and noncompetitive inhibitor of fatty acid amide hydrolase

Scott, Clay W ; Tian, Gaochao ; Yu, Xiao Hong ; Paschetto, Kathy A ; Wilkins, Dee E ; Meury, Luc ; Cao, Chang Qing ; Varnes, Jeffrey ; Edwards, Philip D

European Journal of Pharmacology, 2011, Vol.667(1), pp.74-79 [Peer Reviewed Journal]

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26
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Bioactive maca (Lepidium meyenii) alkamides are a result of traditional Andean postharvest drying practices

Esparza, Eliana ; Hadzich, Antonella ; Kofer, Waltraud ; Mithöfer, Axel ; Cosio, Eric G

Phytochemistry, August 2015, Vol.116, pp.138-148 [Peer Reviewed Journal]

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27
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N ‐Acylethanolamines: lipid metabolites with functions in plant growth and development

Blancaflor, Elison B. ; Kilaru, Aruna ; Keereetaweep, Jantana ; Khan, Bibi Rafeiza ; Faure, Lionel ; Chapman, Kent D.

Plant Journal, August 2014, Vol.79(4), pp.568-583 [Peer Reviewed Journal]

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28
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Lipoxygenase‐derived 9‐hydro(pero)xides of linoleoylethanolamide interact with ABA signaling to arrest root development during Arabidopsis seedling establishment

Keereetaweep, Jantana ; Blancaflor, Elison B. ; Hornung, Ellen ; Feussner, Ivo ; Chapman, Kent D.

Plant Journal, April 2015, Vol.82(2), pp.315-327 [Peer Reviewed Journal]

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29
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Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice

Gamage, Thomas F ; Ignatowska-Jankowska, Bogna M ; Muldoon, Pretal P ; Cravatt, Benjamin F ; Damaj, M. Imad ; Lichtman, Aron H

Drug and Alcohol Dependence, 01 January 2015, Vol.146, pp.7-16 [Peer Reviewed Journal]

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30
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Fatty acid amide hydrolase inhibitors. 2. Novel synthesis of sterically hindered azabenzhydryl ethers and an improved synthesis of VER-156084

Roughley, Stephen D ; Hart, Terance

Tetrahedron Letters, 2010, Vol.51(39), pp.5191-5194 [Peer Reviewed Journal]

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31
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Attenuation of anticipatory nausea in a rat model of contextually elicited conditioned gaping by enhancement of the endocannabinoid system

Limebeer, Cheryl ; Abdullah, Rehab ; Rock, Erin ; Imhof, Elizabeth ; Wang, Kai ; Lichtman, Aron ; Parker, Linda

Psychopharmacology, 2014, Vol.231(3), pp.603-612 [Peer Reviewed Journal]

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32
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Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice

Cassano, Tommaso ; Gaetani, Silvana ; Macheda, Teresa ; Laconca, Leonardo ; Romano, Adele ; Morgese, Maria ; Cimmino, Concetta ; Chiarotti, Flavia ; Bambico, Francis ; Gobbi, Gabriella ; Cuomo, Vincenzo ; Piomelli, Daniele

Psychopharmacology, 2011, Vol.214(2), pp.465-476 [Peer Reviewed Journal]

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First-in-Human Clinical Trials — What We Can Learn from Tragic Failures

Bonini, Sergio

The New England Journal of Medicine, Nov 3, 2016, Vol.375(18), pp.1788-1789 [Peer Reviewed Journal]

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34
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Acute Neurologic Disorder from an Inhibitor of Fatty Acid Amide Hydrolase

Ronzière, Thomas

The New England Journal of Medicine, Nov 3, 2016, Vol.375(18), pp.1717-1725 [Peer Reviewed Journal]

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35
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Expression and localization of the cannabinoid receptor type 1 and the enzyme fatty acid amide hydrolase in the retina of vervet monkeys

Bouskila, J ; Burke, M.W ; Zabouri, N ; Casanova, C ; Ptito, M ; Bouchard, J.-F

Neuroscience, 27 January 2012, Vol.202, pp.117-130 [Peer Reviewed Journal]

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Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors

Kono, Mitsunori ; Matsumoto, Takahiro ; Imaeda, Toshihiro ; Kawamura, Toru ; Fujimoto, Shinji ; Kosugi, Yohei ; Odani, Tomoyuki ; Shimizu, Yuji ; Matsui, Hideki ; Shimojo, Masato ; Kori, Masakuni

Bioorganic & Medicinal Chemistry, 15 February 2014, Vol.22(4), pp.1468-1478 [Peer Reviewed Journal]

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