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19 Results  for Everything (Includes Articles)

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CorrigendumCorrigendum to "The discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists"[Bioorg. Med. Chem. Lett. 12 (2002) 611]

Lin, Linus S ; Kopka, Ihor E ; Mumford, Richard A ; Magriotis, Plato A ; Lanza, Jr, Thomas ; Durette, Philippe L ; Kamenecka, Theodore ; Young, David N ; de Laszlo, Stephen E ; Mccauley, Ermenegilda ; Van Riper, Gail ; Kidambi, Usha ; Egger, Linda A ; Tong, Xinchun ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Fenyk-Melody, Judy ; Schmidt, John A ; Maccoss, Malcolm ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(12), pp.1695-1695 [Peer Reviewed Journal]

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Improved Pharmacokinetics of AMG 517 Through Co-Crystallization Part 2: Analysis of 12 Carboxylic Acid Co-Crystals

Stanton, Mary K. ; Kelly, Ron C. ; Colletti, Adria ; Langley, Meghan ; Munson, Eric J. ; Peterson, Matthew L. ; Roberts, John ; Wells, Mary

Journal of Pharmaceutical Sciences, July 2011, Vol.100(7), pp.2734-2743 [Peer Reviewed Journal]

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Improved pharmacokinetics of AMG 517 through co‐crystallization part 1: Comparison of two acids with corresponding amide co‐crystals

Stanton, Mary K. ; Kelly, Ron C. ; Colletti, Adria ; Kiang, Y. ‐H. ; Langley, Meghan ; Munson, Eric J. ; Peterson, Matthew L. ; Roberts, John ; Wells, Mary

Journal of Pharmaceutical Sciences, September 2010, Vol.99(9), pp.3769-3778 [Peer Reviewed Journal]

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Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors

Peterson, Emily A. ; Boezio, Alessandro A. ; Andrews, Paul S. ; Boezio, Christiane M. ; Bush, Tammy L. ; Cheng, Alan C. ; Choquette, Deborah ; Coats, James R. ; Colletti, Adria E. ; Copeland, Katrina W. ; Dupont, Michelle ; Graceffa, Russell ; Grubinska, Barbara ; Kim, Joseph L. ; Lewis, Richard T. ; Liu, Jingzhou ; Mullady, Erin L. ; Potashman, Michele H. ; Romero, Karina ; Shaffer, Paul L. ; Stanton, Mary K. ; Stellwagen, John C. ; Teffera, Yohannes ; Yi, Shuyan ; Cai, Ti ; La, Daniel S.

Bioorganic & Medicinal Chemistry Letters, 1 August 2012, Vol.22(15), pp.4967-4974 [Peer Reviewed Journal]

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Discovery of triazine-benzimidazoles as selective inhibitors of mTOR

Peterson, Emily A. ; Andrews, Paul S. ; Be, Xuhai ; Boezio, Alessandro A. ; Bush, Tammy L. ; Cheng, Alan C. ; Coats, James R. ; Colletti, Adria E. ; Copeland, Katrina W. ; Dupont, Michelle ; Graceffa, Russell ; Grubinska, Barbara ; Harmange, Jean-Christophe ; Kim, Joseph L. ; Mullady, Erin L. ; Olivieri, Philip ; Schenkel, Laurie B. ; Stanton, Mary K. ; Teffera, Yohannes ; Whittington, Douglas A. ; Cai, Ti ; La, Daniel S.

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(7), pp.2064-2070 [Peer Reviewed Journal]

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Deletion of Abcg2 has differential effects on excretion and pharmacokinetics of probe substrates in rats

Huang, Liyue ; Be, Xuhai ; Tchaparian, Eskouhie H ; Colletti, Adria E ; Roberts, Jonathan ; Langley, Meghan ; Ling, Yun ; Wong, Bradley K ; Jin, Lixia

The Journal of pharmacology and experimental therapeutics, November 2012, Vol.343(2), pp.316-24 [Peer Reviewed Journal]

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Effects of acetaminophen and ibuprofen on renal function in anesthetized normal and sodium-depleted dogs

Colletti, Adria ; Vogl, Helen ; Rahe, Therese ; Zambraski, Edward

Journal of Applied Physiology, Feb 1999, Vol.86(2), pp.592-597 [Peer Reviewed Journal]

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Identification of quinone imine containing glutathione conjugates of diclofenac in rat bile

Waldon, Daniel J ; Teffera, Yohannes ; Colletti, Adria E ; Liu, Jingzhou ; Zurcher, Danielle ; Copeland, Katrina W ; Zhao, Zhiyang

Chemical research in toxicology, 20 December 2010, Vol.23(12), pp.1947-53 [Peer Reviewed Journal]

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Bioactivation of isothiazoles: minimizing the risk of potential toxicity in drug discovery

Teffera, Yohannes ; Choquette, Deborah ; Liu, Jingzhou ; Colletti, Adria E ; Hollis, L Steven ; Lin, Min-Hwa Jasmine ; Zhao, Zhiyang

Chemical research in toxicology, 15 November 2010, Vol.23(11), pp.1743-52 [Peer Reviewed Journal]

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Absorption, Tissue Distribution, Excretion, and Metabolism of 3 H- and 14 C-Labeled Emamectin Benzoate in Rats
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Absorption, Tissue Distribution, Excretion, and Metabolism of 3 H- and 14 C-Labeled Emamectin Benzoate in Rats

Mushtaq, Mohammad ; Syintsakos, Loretta R. ; Krieter, Philip A. ; Colletti, Adria ; Arison, Byron ; Crouch, Louis S. ; Wislocki, Peter G.

Journal of Agricultural and Food Chemistry, 01/1996, Vol.44(10), pp.3342-3349 [Peer Reviewed Journal]

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11
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Amidines as amide bond replacements in VLA-4 antagonists

Kamenecka, Theodore M ; Park, You-Jung ; Lin, Linus S ; de Laszlo, Stephen ; Mccauley, Ermengilda D ; Van Riper, Gail ; Egger, Linda ; Kidambi, Usha ; Mumford, Richard A ; Tong, Sharon ; Tang, Wei ; Colletti, Adria ; Teffera, Yohannes ; Stearns, Ralph ; Maccoss, Malcolm ; Schmidt, John A ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 3 May 2004, Vol.14(9), pp.2323-2326 [Peer Reviewed Journal]

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Substituted N-(3,5-Dichlorobenzenesulfonyl)- l-prolyl-phenylalanine analogues as potent VLA-4 antagonists

Kopka, Ihor E ; Young, David N ; Lin, Linus S ; Mumford, Richard A ; Magriotis, Plato A ; Maccoss, Malcolm ; Mills, Sander G ; Riper, Gail Van ; Mccauley, Ermengilda ; Egger, Linda E ; Kidambi, Usha ; Schmidt, John A ; Lyons, Kathryn ; Stearns, Ralph ; Vincent, Stella ; Colletti, Adria ; Wang, Zhen ; Tong, Sharon ; Wang, Junying ; Zheng, Song ; Owens, Karen ; Levorse, Dorothy ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(4), pp.637-640 [Peer Reviewed Journal]

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The Discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists

Lin, Linus S. ; Kopka, Ihor E. ; Mumford, Richard A. ; Magriotis, Plato A. ; Lanza, Thomas ; Durette, Philippe L. ; Kamenecka, Theodore ; Young, David N. ; Laszlo, Stephen E.de ; Mccauley, Ermenegilda ; Riper, Gail Van ; Kidambi, Usha ; Egger, Linda A. ; Tong, Xinchun ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Fenyk-Melody, Judy ; Schmidt, John A. ; Maccoss, Malcolm ; Hagmann, William K.

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(4), pp.611-614 [Peer Reviewed Journal]

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14
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Substituted 3-amino biaryl propionic acids as potent VLA-4 antagonists

Kopka, Ihor E ; Lin, Linus S ; Mumford, Richard A ; Lanza, Thomas ; Magriotis, Plato A ; Young, David ; Delaszlo, Stephen E ; Maccoss, Malcolm ; Mills, Sander G ; Van Riper, Gail ; Mccauley, Ermengilda ; Lyons, Kathryn ; Vincent, Stella ; Egger, Linda A ; Kidambi, Usha ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Tong, Sharon ; Owens, Karen ; Levorse, Dorothy ; Schmidt, John A ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(17), pp.2415-2418 [Peer Reviewed Journal]

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15
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Chemical reactivity of methoxy 4-o-aryl quinolines: identification of glutathione displacement products in vitro and in vivo

Teffera, Yohannes ; Colletti, Adria E ; Harmange, Jean Christophe ; Hollis, L Steven ; Albrecht, Brian K ; Boezio, Alessandro A ; Liu, Jingzhou ; Zhao, Zhiyang

Chemical research in toxicology, November 2008, Vol.21(11), pp.2216-22 [Peer Reviewed Journal]

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16
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The discovery of sulfonylated dipeptides as Potent VLA-4 antagonists

Hagmann, William K ; Durette, Philippe L ; Lanza, Thomas ; Kevin, Nancy Jo ; de Laszlo, Stephen E ; Kopka, Ihor E ; Young, David ; Magriotis, Plato A ; Li, Bing ; Lin, Linus S ; Yang, Ginger ; Kamenecka, Theodore ; Chang, Linda L ; Wilson, Jonathan ; Maccoss, Malcolm ; Mills, Sander G ; Van Riper, Gail ; Mccauley, Ermengilda ; Egger, Linda A ; Kidambi, Usha ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Johannes ; Tong, Sharon ; Fenyk-Melody, Judy ; Owens, Karen ; Levorse, Dorothy ; Kim, Philip ; Schmidt, John A ; Mumford, Richard A

Bioorganic & Medicinal Chemistry Letters, 2001, Vol.11(20), pp.2709-2713 [Peer Reviewed Journal]

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Inhibition of Stromelysin-1 (MMP-3) by P 1 ‘-Biphenylylethyl Carboxyalkyl Dipeptides
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Inhibition of Stromelysin-1 (MMP-3) by P 1 ‘-Biphenylylethyl Carboxyalkyl Dipeptides

Esser, Craig K. ; Bugianesi, Robert L. ; Caldwell, Charles G. ; Chapman, Kevin T. ; Durette, Philippe L. ; Girotra, Narindar N. ; Kopka, Ihor E. ; Lanza, Thomas J. ; Levorse, Dorothy A. ; Maccoss, Malcolm ; Owens, Karen A. ; Ponpipom, Mitree M. ; Simeone, Joseph P. ; Harrison, Richard K. ; Niedzwiecki, Lisa ; Becker, Joseph W. ; Marcy, Alice I. ; Axel, Melinda G. ; Christen, Amy J. ; Mcdonnell, Joseph ; Moore, Vernon L. ; Olszewski, Julie M. ; Saphos, Cheryl ; Visco, Denise M. ; Shen, Frank ; Colletti, Adria ; Krieter, Philip A. ; Hagmann, William K.

Journal of Medicinal Chemistry, 03/1997, Vol.40(6), pp.1026-1040 [Peer Reviewed Journal]

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Enantiomer ratio of MK‐0767 in humans and nonclinical species

Shen, Zhongzhou ; Bakhtiar, Ray ; Komuro, Masakatsu ; Awano, Katsuya ; Taga, Fukutaro ; Colletti, Adria ; Hora, Don ; Feeney, William ; Iliff, Susan ; Franklin, Ronald B. ; Vincent, Stella

Rapid Communications in Mass Spectrometry, 15 May 2005, Vol.19(9), pp.1125-1129 [Peer Reviewed Journal]

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19
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The discovery of acylated beta-amino acids as potent and orally bioavailable VLA-4 antagonists

Lin, Linus S ; Kopka, Ihor E ; Mumford, Richard A ; Magriotis, Plato A ; Lanza, Thomas ; Durette, Philippe L ; Kamenecka, Theodore ; Young, David N ; De Laszlo, Stephen E ; Mccauley, Ermenegilda ; Riper, Gail Van ; Kidambi, Usha ; Egger, Linda A ; Tong, Xinchun ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Fenyk-Melody, Judy ; Schmidt, John A ; Maccoss, Malcolm ; Hagmann, William K

Bioorganic & medicinal chemistry letters, 25 February 2002, Vol.12(4), pp.611-4 [Peer Reviewed Journal]

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