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20 Results  for Everything (Includes Articles)

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Species difference in glucuronidation formation kinetics with a selective mTOR inhibitor

Berry, Loren M ; Liu, Jingzhou ; Colletti, Adria ; Krolikowski, Paul ; Zhao, Zhiyang ; Teffera, Yohannes

Drug metabolism and disposition: the biological fate of chemicals, April 2014, Vol.42(4), pp.707-17 [Peer Reviewed Journal]

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Deletion of Abcg2 has differential effects on excretion and pharmacokinetics of probe substrates in rats

Huang, Liyue ; Be, Xuhai ; Tchaparian, Eskouhie H ; Colletti, Adria E ; Roberts, Jonathan ; Langley, Meghan ; Ling, Yun ; Wong, Bradley K ; Jin, Lixia

The Journal of pharmacology and experimental therapeutics, November 2012, Vol.343(2), pp.316-24 [Peer Reviewed Journal]

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Effects of acetaminophen and ibuprofen on renal function in anesthetized normal and sodium-depleted dogs

Colletti, Adria ; Vogl, Helen ; Rahe, Therese ; Zambraski, Edward

Journal of Applied Physiology, Feb 1999, Vol.86(2), pp.592-597 [Peer Reviewed Journal]

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Identification of quinone imine containing glutathione conjugates of diclofenac in rat bile

Waldon, Daniel J ; Teffera, Yohannes ; Colletti, Adria E ; Liu, Jingzhou ; Zurcher, Danielle ; Copeland, Katrina W ; Zhao, Zhiyang

Chemical research in toxicology, 20 December 2010, Vol.23(12), pp.1947-53 [Peer Reviewed Journal]

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Relationship between passive permeability, efflux, and predictability of clearance from in vitro metabolic intrinsic clearance

Huang, Liyue ; Berry, Loren ; Ganga, Sindhura ; Janosky, Brett ; Chen, April ; Roberts, Jonathan ; Colletti, Adria E ; Lin, Min-Hwa Jasmine

Drug metabolism and disposition: the biological fate of chemicals, February 2010, Vol.38(2), pp.223-31 [Peer Reviewed Journal]

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Bioactivation of isothiazoles: minimizing the risk of potential toxicity in drug discovery

Teffera, Yohannes ; Choquette, Deborah ; Liu, Jingzhou ; Colletti, Adria E ; Hollis, L Steven ; Lin, Min-Hwa Jasmine ; Zhao, Zhiyang

Chemical research in toxicology, 15 November 2010, Vol.23(11), pp.1743-52 [Peer Reviewed Journal]

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7
Absorption, Tissue Distribution, Excretion, and Metabolism of 3 H- and 14 C-Labeled Emamectin Benzoate in Rats
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Absorption, Tissue Distribution, Excretion, and Metabolism of 3 H- and 14 C-Labeled Emamectin Benzoate in Rats

Mushtaq, Mohammad ; Syintsakos, Loretta R. ; Krieter, Philip A. ; Colletti, Adria ; Arison, Byron ; Crouch, Louis S. ; Wislocki, Peter G.

Journal of Agricultural and Food Chemistry, 01/1996, Vol.44(10), pp.3342-3349 [Peer Reviewed Journal]

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8
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Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors

Peterson, Emily A ; Boezio, Alessandro A ; Andrews, Paul S ; Boezio, Christiane M ; Bush, Tammy L ; Cheng, Alan C ; Choquette, Deborah ; Coats, James R ; Colletti, Adria E ; Copeland, Katrina W ; Dupont, Michelle ; Graceffa, Russell ; Grubinska, Barbara ; Kim, Joseph L ; Lewis, Richard T ; Liu, Jingzhou ; Mullady, Erin L ; Potashman, Michele H ; Romero, Karina ; Shaffer, Paul L

Bioorganic & Medicinal Chemistry Letters, 01 August 2012, Vol.22(15), pp.4967-4974 [Peer Reviewed Journal]

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Discovery of triazine-benzimidazoles as selective inhibitors of mTOR

Peterson, Emily A ; Andrews, Paul S ; Be, Xuhai ; Boezio, Alessandro A ; Bush, Tammy L ; Cheng, Alan C ; Coats, James R ; Colletti, Adria E ; Copeland, Katrina W ; Dupont, Michelle ; Graceffa, Russell ; Grubinska, Barbara ; Harmange, Jean-Christophe ; Kim, Joseph L ; Mullady, Erin L ; Olivieri, Philip ; Schenkel, Laurie B ; Stanton, Mary K ; Teffera, Yohannes ; Whittington, Douglas A

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(7), pp.2064-2070 [Peer Reviewed Journal]

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Chemical reactivity of methoxy 4-o-aryl quinolines: identification of glutathione displacement products in vitro and in vivo

Teffera, Yohannes ; Colletti, Adria E ; Harmange, Jean Christophe ; Hollis, L Steven ; Albrecht, Brian K ; Boezio, Alessandro A ; Liu, Jingzhou ; Zhao, Zhiyang

Chemical research in toxicology, November 2008, Vol.21(11), pp.2216-22 [Peer Reviewed Journal]

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Inhibition of Stromelysin-1 (MMP-3) by P 1 ‘-Biphenylylethyl Carboxyalkyl Dipeptides
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Inhibition of Stromelysin-1 (MMP-3) by P 1 ‘-Biphenylylethyl Carboxyalkyl Dipeptides

Esser, Craig K. ; Bugianesi, Robert L. ; Caldwell, Charles G. ; Chapman, Kevin T. ; Durette, Philippe L. ; Girotra, Narindar N. ; Kopka, Ihor E. ; Lanza, Thomas J. ; Levorse, Dorothy A. ; Maccoss, Malcolm ; Owens, Karen A. ; Ponpipom, Mitree M. ; Simeone, Joseph P. ; Harrison, Richard K. ; Niedzwiecki, Lisa ; Becker, Joseph W. ; Marcy, Alice I. ; Axel, Melinda G. ; Christen, Amy J. ; Mcdonnell, Joseph ; Moore, Vernon L. ; Olszewski, Julie M. ; Saphos, Cheryl ; Visco, Denise M. ; Shen, Frank ; Colletti, Adria ; Krieter, Philip A. ; Hagmann, William K.

Journal of Medicinal Chemistry, 03/1997, Vol.40(6), pp.1026-1040 [Peer Reviewed Journal]

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12
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Enantiomer ratio of MK‐0767 in humans and nonclinical species

Shen, Zhongzhou ; Bakhtiar, Ray ; Komuro, Masakatsu ; Awano, Katsuya ; Taga, Fukutaro ; Colletti, Adria ; Hora, Don ; Feeney, William ; Iliff, Susan ; Franklin, Ronald B. ; Vincent, Stella

Rapid Communications in Mass Spectrometry, 15 May 2005, Vol.19(9), pp.1125-1129 [Peer Reviewed Journal]

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13
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Amidines as amide bond replacements in VLA-4 antagonists

Kamenecka, Theodore M ; Park, You-Jung ; Lin, Linus S ; de Laszlo, Stephen ; Mccauley, Ermengilda D ; Van Riper, Gail ; Egger, Linda ; Kidambi, Usha ; Mumford, Richard A ; Tong, Sharon ; Tang, Wei ; Colletti, Adria ; Teffera, Yohannes ; Stearns, Ralph ; Maccoss, Malcolm ; Schmidt, John A ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 03 May 2004, Vol.14(9), pp.2323-2326 [Peer Reviewed Journal]

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14
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The pharmacokinetics of a thiazole benzenesulfonamide beta 3-adrenergic receptor agonist and its analogs in rats, dogs, and monkeys: improving oral bioavailability

Stearns, Ralph A ; Miller, Randy R ; Tang, Wei ; Kwei, Gloria Y ; Tang, Frank S ; Mathvink, Robert J ; Naylor, Elizabeth M ; Chitty, Dawn ; Colandrea, Vincent J ; Weber, Ann E ; Colletti, Adria E ; Strauss, John R ; Keohane, Carol Ann ; Feeney, William P ; Iliff, Susan A ; Chiu, Shuet-Hing Lee

Drug metabolism and disposition: the biological fate of chemicals, July 2002, Vol.30(7), pp.771-7 [Peer Reviewed Journal]

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15
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Substituted N-(3,5-Dichlorobenzenesulfonyl)- l-prolyl-phenylalanine analogues as potent VLA-4 antagonists

Kopka, Ihor E ; Young, David N ; Lin, Linus S ; Mumford, Richard A ; Magriotis, Plato A ; Maccoss, Malcolm ; Mills, Sander G ; Riper, Gail Van ; Mccauley, Ermengilda ; Egger, Linda E ; Kidambi, Usha ; Schmidt, John A ; Lyons, Kathryn ; Stearns, Ralph ; Vincent, Stella ; Colletti, Adria ; Wang, Zhen ; Tong, Sharon ; Wang, Junying ; Zheng, Song

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(4), pp.637-640 [Peer Reviewed Journal]

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16
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The Discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists

Lin, Linus S ; Kopka, Ihor E ; Mumford, Richard A ; Magriotis, Plato A ; Lanza, Thomas ; Durette, Philippe L ; Kamenecka, Theodore ; Young, David N ; Laszlo, Stephen E.de ; Mccauley, Ermenegilda ; Riper, Gail Van ; Kidambi, Usha ; Egger, Linda A ; Tong, Xinchun ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Fenyk-Melody, Judy

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(4), pp.611-614 [Peer Reviewed Journal]

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17
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The discovery of acylated beta-amino acids as potent and orally bioavailable VLA-4 antagonists

Lin, Linus S ; Kopka, Ihor E ; Mumford, Richard A ; Magriotis, Plato A ; Lanza, Thomas ; Durette, Philippe L ; Kamenecka, Theodore ; Young, David N ; De Laszlo, Stephen E ; Mccauley, Ermenegilda ; Riper, Gail Van ; Kidambi, Usha ; Egger, Linda A ; Tong, Xinchun ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Fenyk-Melody

Bioorganic & medicinal chemistry letters, 25 February 2002, Vol.12(4), pp.611-4 [Peer Reviewed Journal]

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18
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Substituted 3-amino biaryl propionic acids as potent VLA-4 antagonists

Kopka, Ihor E ; Lin, Linus S ; Mumford, Richard A ; Lanza, Thomas ; Magriotis, Plato A ; Young, David ; Delaszlo, Stephen E ; Maccoss, Malcolm ; Mills, Sander G ; Van Riper, Gail ; Mccauley, Ermengilda ; Lyons, Kathryn ; Vincent, Stella ; Egger, Linda A ; Kidambi, Usha ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Tong, Sharon ; Owens, Karen

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(17), pp.2415-2418 [Peer Reviewed Journal]

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CorrigendumCorrigendum to “The discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists”[Bioorg. Med. Chem. Lett. 12 (2002) 611]

Lin, Linus S ; Kopka, Ihor E ; Mumford, Richard A ; Magriotis, Plato A ; Lanza, Jr, Thomas ; Durette, Philippe L ; Kamenecka, Theodore ; Young, David N ; de Laszlo, Stephen E ; Mccauley, Ermenegilda ; Van Riper, Gail ; Kidambi, Usha ; Egger, Linda A ; Tong, Xinchun ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Fenyk-Melody, Judy ; Schmidt, John A ; Maccoss, Malcolm ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(12), pp.1695-1695 [Peer Reviewed Journal]

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20
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The discovery of sulfonylated dipeptides as Potent VLA-4 antagonists

Hagmann, William K ; Durette, Philippe L ; Lanza, Thomas ; Kevin, Nancy Jo ; de Laszlo, Stephen E ; Kopka, Ihor E ; Young, David ; Magriotis, Plato A ; Li, Bing ; Lin, Linus S ; Yang, Ginger ; Kamenecka, Theodore ; Chang, Linda L ; Wilson, Jonathan ; Maccoss, Malcolm ; Mills, Sander G ; Van Riper, Gail ; Mccauley, Ermengilda ; Egger, Linda A ; Kidambi, Usha

Bioorganic & Medicinal Chemistry Letters, 2001, Vol.11(20), pp.2709-2713 [Peer Reviewed Journal]

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