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10 Results  for Everything (Includes Articles)

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In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: Identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism

Vincent, Styliani H ; Karanam, Bindhu V ; Painter, Susan K ; Chiu, Shuet-Hing L

Archives of Biochemistry and Biophysics, 1992, Vol.294(2), pp.454-460 [Peer Reviewed Journal]

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1-[2( R )-(2-Amino-2-methylpropionylamino)-3-(1 H -indol-3-yl)propionyl]-3- benzylpiperidine-3( S )-carboxylic Acid Ethyl Ester (L-163,540):  A Potent, Orally Bioavailable, and Short-Duration Growth Hormone Secretagogue
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1-[2( R )-(2-Amino-2-methylpropionylamino)-3-(1 H -indol-3-yl)propionyl]-3- benzylpiperidine-3( S )-carboxylic Acid Ethyl Ester (L-163,540):  A Potent, Orally Bioavailable, and Short-Duration Growth Hormone Secretagogue

Yang, Lihu ; Morriello, Greg ; Patchett, Arthur A. ; Leung, Kwan ; Jacks, Tom ; Cheng, Kang ; Schleim, Klaus D. ; Feeney, William ; Chan, Wanda W.-S. ; Chiu, Shuet-Hing L. ; Smith, Roy G.

Journal of Medicinal Chemistry, 07/1998, Vol.41(14), pp.2439-2441 [Peer Reviewed Journal]

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Parallel extraction columns and parallel analytical columns coupled with liquid chromatography/tandem mass spectrometry for on‐line simultaneous quantification of a drug candidate and its six metabolites in dog plasma

Xia, Yuan‐Qing ; Hop, Cornelis E. C. A. ; Liu, David Q. ; Vincent, Stella H. ; Chiu, ShuetHing L.

Rapid Communications in Mass Spectrometry, 30 November 2001, Vol.15(22), pp.2135-2144 [Peer Reviewed Journal]

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Roles of Human Hepatic Cytochrome P450s 2C9 and 3A4 in the Metabolic Activation of Diclofenac †
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Roles of Human Hepatic Cytochrome P450s 2C9 and 3A4 in the Metabolic Activation of Diclofenac †

Tang, Wei ; Stearns, Ralph A. ; Wang, Regina W. ; Chiu, Shuet-Hing L. ; Baillie, Thomas A.

Chemical Research in Toxicology, 02/1999, Vol.12(2), pp.192-199 [Peer Reviewed Journal]

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Metabolism of a thiazole benzenesulfonamide derivative, a potent and elective agonist of the human beta3-adrenergic receptor, in rats: identification of a novel isethionic acid conjugate

Tang, Wei ; Stearns, Ralph A ; Miller, Randall R ; Ngui, Jason S ; Mathvink, Robert J ; Weber, Ann E ; Kwei, Gloria Y ; Strauss, John R ; Keohane, Carol A ; Doss, George A ; Chiu, Shuet-Hing L ; Baillie, Thomas A

Drug metabolism and disposition: the biological fate of chemicals, July 2002, Vol.30(7), pp.778-87 [Peer Reviewed Journal]

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Brain penetration of aprepitant, a substance P receptor antagonist, in ferrets

Huskey, Su-Er W ; Dean, Brian J ; Bakhtiar, Ray ; Sanchez, Rosa I ; Tattersall, F David ; Rycroft, Wayne ; Hargreaves, Richard ; Watt, Alan P ; Chicchi, Gary G ; Keohane, Carolann ; Hora, Donald F ; Chiu, Shuet-Hing L

Drug metabolism and disposition: the biological fate of chemicals, June 2003, Vol.31(6), pp.785-91 [Peer Reviewed Journal]

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The metabolic disposition of aprepitant, a substance P receptor antagonist, in rats and dogs

Huskey, Su-Er W ; Dean, Brian J ; Doss, George A ; Wang, Zhen ; Hop, Cornelis E C A ; Anari, Reza ; Finke, Paul E ; Robichaud, Albert J ; Zhang, Minghua ; Wang, Bonnie ; Strauss, John R ; Cunningham, Paul K ; Feeney, William P ; Franklin, Ronald B ; Baillie, Thomas A ; Chiu, Shuet-Hing L

Drug metabolism and disposition: the biological fate of chemicals, February 2004, Vol.32(2), pp.246-58 [Peer Reviewed Journal]

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Identification of metabolites of a substance P (neurokinin 1 receptor) antagonist in rat hepatocytes and rat plasma

Hop, Cornelis E C A ; Wang, Yanfeng ; Kumar, Sanjeev ; Elipe, Maria Victoria Silva ; Raab, Conrad E ; Dean, Dennis C ; Poon, Grace K ; Keohane, Carol-Ann ; Strauss, John ; Chiu, Shuet-Hing L ; Curtis, Neil ; Elliott, Jason ; Gerhard, Ute ; Locker, Karen ; Morrison, Denise ; Mortishire-Smith, Russell ; Thomas, Steven ; Watt, Alan P ; Evans, David C

Drug metabolism and disposition: the biological fate of chemicals, August 2002, Vol.30(8), pp.937-43 [Peer Reviewed Journal]

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L-770,644: A potent and selective human β3 adrenergic receptor agonist with improved oral bioavailability

Shih, Thomas L ; Candelore, Mari R ; Cascieri, Margaret A ; Chiu, Shuet-Hing L ; Colwell, Lawrence F ; Deng, Liping ; Feeney, William P ; Forrest, Michael J ; Hom, Gary J ; Macintyre, D.Euan ; Miller, Randall R ; Stearns, Ralph A ; Strader, Catherine D ; Tota, Laurie ; Wyvratt, Matthew J ; Fisher, Michael H ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 1999, Vol.9(9), pp.1251-1254 [Peer Reviewed Journal]

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3-Pyridyloxypropanolamine agonists of the β3 adrenergic receptor with improved pharmacokinetic properties

Weber, Ann E ; Ok, Hyun O ; Alvaro, Raul F ; Candelore, Mari R ; Cascieri, Margaret A ; Chiu, Shuet-Hing L ; Deng, Liping ; Forrest, Michael J ; Hom, Gary J ; Hutchins, Jennifer E ; Kao, John ; Macintyre, D.Euan ; Mathvink, Robert J ; Mcloughlin, Debra ; Miller, Randall R ; Newbold, Ronald C ; Olah, Timothy V ; Parmee, Emma R ; Perkins, Leroy ; Stearns, Ralph A

Bioorganic & Medicinal Chemistry Letters, 1998, Vol.8(16), pp.2111-2116 [Peer Reviewed Journal]

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