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1
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Differential effects of oxyntomodulin and GLP-1 on glucose metabolism

Du, Xiaobing ; Kosinski, Jennifer R ; Lao, Julie ; Shen, Xiaolan ; Petrov, Aleksandr ; Chicchi, Gary G ; Eiermann, George J ; Pocai, Alessandro

American journal of physiology. Endocrinology and metabolism, 15 July 2012, Vol.303(2), pp.E265-71 [Peer Reviewed Journal]

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2
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A novel series of indazole-/indole-based glucagon receptor antagonists

Lin, Songnian ; Zhang, Fengqi ; Jiang, Guoqiang ; Qureshi, Sajjad A ; Yang, Xiaodong ; Chicchi, Gary G ; Tota, Laurie ; Bansal, Alka ; Brady, Edward ; Trujillo, Maria ; Salituro, Gino ; Miller, Corey ; Tata, James R ; Zhang, Bei B ; Parmee, Emma R

Bioorganic & Medicinal Chemistry Letters, 01 October 2015, Vol.25(19), pp.4143-4147 [Peer Reviewed Journal]

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Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists

Lai, Zhong ; He, Shuwen ; Sherer, Edward C ; Wu, Zhicai ; Yu, Yang ; Ball, Richard ; Hong, Qingmei ; Yang, David X ; Guo, Liangqing ; Li, Derun ; Tuang, Quang ; Chicchi, Gary G ; Trusca, Dorina ; Tsao, Kwei-Lan ; Zhou, Yun-Ping ; Howard, Andrew D ; Nargund, Ravi P ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 01 September 2015, Vol.25(17), pp.3520-3525 [Peer Reviewed Journal]

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4
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The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin

Kosinski, Jennifer R ; Hubert, James ; Carrington, Paul E ; Chicchi, Gary G ; Mu, James ; Miller, Corey ; Cao, Jin ; Bianchi, Elisabetta ; Pessi, Antonello ; Sinharoy, Ranabir ; Marsh, Donald J ; Pocai, Alessandro

Obesity (Silver Spring, Md.), August 2012, Vol.20(8), pp.1566-71 [Peer Reviewed Journal]

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5
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Modulation of basal and stress‐induced amygdaloid substance P release by the potent and selective NK1 receptor antagonist L‐822429

Singewald, Nicolas ; Chicchi, Gary G. ; Thurner, Clemens C. ; Tsao, Kwei‐Lan ; Spetea, Mariana ; Schmidhammer, Helmut ; Sreepathi, Hari Kishore ; Ferraguti, Francesco ; Singewald, Georg M. ; Ebner, Karl

Journal of Neurochemistry, September 2008, Vol.106(6), pp.2476-2488 [Peer Reviewed Journal]

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6
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Tetrahydroindolizinone NK 1 antagonists

Bao, Jianming ; Lu, Huagang ; Morriello, Gregori J ; Carlson, Emma J ; Wheeldon, Alan ; Chicchi, Gary G ; Kurtz, Marc M ; Tsao, Kwei-Lan C ; Zheng, Song ; Tong, Xinchun ; Mills, Sander G ; Devita, Robert J

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(7), pp.2354-2358 [Peer Reviewed Journal]

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7
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Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst3 Antagonist

Pasternak, Alexander ; Feng, Zhe ; De Jesus, Reynalda ; Ye, Zhixiong ; He, Shuwen ; Dobbelaar, Peter ; Bradley, Scott A ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Eiermann, George J ; Li, Cai ; Feng, Yue ; Wu, Margaret ; Shao, Qing ; Zhang, Bei B ; Nargund, Ravi ; Mills, Sander G ; Howard, Andrew D ; Yang, Lihu ; Zhou, Yun-Ping

ACS medicinal chemistry letters, 12 April 2012, Vol.3(4), pp.289-93 [Peer Reviewed Journal]

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8
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Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists

Li, Derun ; Wu, Zhicai ; Yu, Yang ; Ball, Richard G ; Guo, Liangqin ; Sherer, Edward ; He, Shuwen ; Hong, Qingmei ; Lai, Zhong ; Qi, Hongbo ; Truong, Quang ; Yang, David X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Trujillo, Maria ; Pachanski, Michele ; Eiermann, George J ; Howard, Andrew D ; Zhou, Yun-Ping ; Zhang, Bei B ; Nargund, Ravi P ; Hagmann, William K

ACS medicinal chemistry letters, 12 June 2014, Vol.5(6), pp.690-5 [Peer Reviewed Journal]

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9
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Potent, brain-penetrant, hydroisoindoline-based human neurokinin-1 receptor antagonists

Jiang, Jinlong ; Bunda, Jaime L ; Doss, Geoge A ; Chicchi, Gary G ; Kurtz, Marc M ; Tsao, Kwei-Lan C ; Tong, Xinchun ; Zheng, Song ; Upthagrove, Alana ; Samuel, Koppara ; Tschirret-Guth, Richard ; Kumar, Sanjeev ; Wheeldon, Alan ; Carlson, Emma J ; Hargreaves, Richard ; Burns, Donald ; Hamill, Terence ; Ryan, Christine ; Krause, Stephen M ; Eng, Waisi ; Devita, Robert J ; Mills, Sander G

Journal of medicinal chemistry, 14 May 2009, Vol.52(9), pp.3039-46 [Peer Reviewed Journal]

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10
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Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice

Pocai, Alessandro ; Carrington, Paul E ; Adams, Jennifer R ; Wright, Michael ; Eiermann, George ; Zhu, Lan ; Du, Xiaobing ; Petrov, Aleksandr ; Lassman, Michael E ; Jiang, Guoqiang ; Liu, Franklin ; Miller, Corey ; Tota, Laurie M ; Zhou, Gaochao ; Zhang, Xiaoping ; Sountis, Michael M ; Santoprete, Alessia ; Capito', Elena ; Chicchi, Gary G ; Thornberry, Nancy ; Bianchi, Elisabetta ; Pessi, Antonello ; Marsh, Donald J ; Sinharoy, Ranabir

Diabetes, October 2009, Vol.58(10), pp.2258-66 [Peer Reviewed Journal]

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11
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Fused bicyclic pyrrolizinones as new scaffolds for human NK 1 antagonists

Morriello, Gregori J ; Devita, Robert J ; Mills, Sander G ; Young, Jonathan R ; Lin, Peter ; Doss, George ; Chicchi, Gary G ; Demartino, Julie ; Kurtz, Marc M ; Tsao, Kwei-Lan C ; Carlson, Emma ; Townson, Karen ; Wheeldon, Alan ; Boyce, Susan ; Collinson, Neil ; Rupniak, Nadia ; Moore, Stephen

Bioorganic & Medicinal Chemistry, 2008, Vol.16(5), pp.2156-2170 [Peer Reviewed Journal]

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12
An Orally Active, Water-Soluble Neurokinin-1 Receptor Antagonist Suitable for Both Intravenous and Oral Clinical Administration
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An Orally Active, Water-Soluble Neurokinin-1 Receptor Antagonist Suitable for Both Intravenous and Oral Clinical Administration

Harrison, Timothy ; Owens, Andrew P. ; Williams, Brian J. ; Swain, Christopher J. ; Williams, Angela ; Carlson, Emma J. ; Rycroft, Wayne ; Tattersall, F. David ; Cascieri, Margaret A. ; Chicchi, Gary G. ; Sadowski, Sharon ; Rupniak, Nadia M. J. ; Hargreaves, Richard J.

Journal of Medicinal Chemistry, 11/2001, Vol.44(24), pp.4296-4299 [Peer Reviewed Journal]

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13
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Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists

He, Shuwen ; Lai, Zhong ; Ye, Zhixiong ; Dobbelaar, Peter H ; Shah, Shrenik K ; Truong, Quang ; Du, Wu ; Guo, Liangqin ; Liu, Jian ; Jian, Tianying ; Qi, Hongbo ; Bakshi, Raman K ; Hong, Qingmei ; Dellureficio, James ; Reibarkh, Mikhail ; Samuel, Koppara ; Reddy, Vijay B ; Mitelman, Stan ; Tong, Sharon X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Wu, Margaret ; Shao, Qing ; Trujillo, Maria E ; Fernandez, Guillermo ; Nelson, Donald ; Bunting, Patricia ; Kerr, Janet ; Fitzgerald, Patrick ; Morissette, Pierre ; Volksdorf, Sylvia ; Eiermann, George J ; Li, Cai ; Zhang, Bei ; Howard, Andrew D ; Zhou, Yun-Ping ; Nargund, Ravi P ; Hagmann, William K

ACS medicinal chemistry letters, 10 July 2014, Vol.5(7), pp.748-53 [Peer Reviewed Journal]

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14
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SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists

He, Shuwen ; Dobbelaar, Peter H ; Guo, Liangqin ; Ye, Zhixiong ; Liu, Jian ; Jian, Tianying ; Truong, Quang ; Shah, Shrenik K ; Du, Wu ; Qi, Hongbo ; Bakshi, Raman K ; Hong, Qingmei ; Dellureficio, James D ; Sherer, Edward ; Pasternak, Alexander ; Feng, Zhe ; Reibarkh, Mikhail ; Lin, Melissa ; Samuel, Koppara ; Reddy, Vijay B ; Mitelman, Stan ; Tong, Sharon X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Wu, Margaret ; Shao, Qing ; Trujillo, Maria E ; Fernandez, Guillermo ; Nelson, Donald ; Bunting, Patricia ; Kerr, Janet ; Fitzgerald, Patrick ; Morissette, Pierre ; Volksdorf, Sylvia ; Eiermann, George J ; Li, Cai ; Zhang, Bei B ; Howard, Andrew D ; Zhou, Yun-Ping ; Nargund, Ravi P ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 15 March 2016, Vol.26(6), pp.1529-1535 [Peer Reviewed Journal]

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15
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A comparative autoradiographic study of the distributions of substance P and eledoisin binding sites in rat brain

Danks, Janine A ; Rothman, Richard B ; Cascieri, Margaret A ; Chicchi, Gary G ; Liang, Tehming ; Herkenham, Miles

Brain Research, 1986, Vol.385(2), pp.273-281 [Peer Reviewed Journal]

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16
4,4-Disubstituted Piperidine High-Affinity NK 1 Antagonists:  Structure−Activity Relationships and in Vivo Activity
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4,4-Disubstituted Piperidine High-Affinity NK 1 Antagonists:  Structure−Activity Relationships and in Vivo Activity

Stevenson, Graeme I. ; Huscroft, Ian ; Macleod, Angus M. ; Swain, Christopher J. ; Cascieri, Margaret A. ; Chicchi, Gary G. ; Graham, Michael I. ; Harrison, Timothy ; Kelleher, Fintan J. ; Kurtz, Marc ; Ladduwahetty, Tamara ; Merchant, Kevin J. ; Metzger, Joseph M. ; Macintyre, D. E. ; Sadowski, Sharon ; Sohal, Balbinder ; Owens, Andrew P.

Journal of Medicinal Chemistry, 11/1998, Vol.41(23), pp.4623-4635 [Peer Reviewed Journal]

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17
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Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes

Shah, Shrenik K ; He, Shuwen ; Guo, Liangqin ; Truong, Quang ; Qi, Hongbo ; Du, Wu ; Lai, Zhong ; Liu, Jian ; Jian, Tianying ; Hong, Qingmei ; Dobbelaar, Peter ; Ye, Zhixiong ; Sherer, Edward ; Feng, Zhe ; Yu, Yang ; Wong, Frederick ; Samuel, Koppara ; Madiera, Maria ; Karanam, Bindhu V ; Reddy, Vijay B ; Mitelman, Stan ; Tong, Sharon X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Feng, Yue ; Wu, Margaret ; Shao, Qing ; Trujillo, Maria E ; Eiermann, George J ; Li, Cai ; Pachanski, Michele ; Fernandez, Guillermo ; Nelson, Donald ; Bunting, Patricia ; Morissette, Pierre ; Volksdorf, Sylvia ; Kerr, Janet ; Zhang, Bei B ; Howard, Andrew D ; Zhou, Yun-Ping ; Pasternak, Alexander ; Nargund, Ravi P ; Hagmann, William K

ACS medicinal chemistry letters, 14 May 2015, Vol.6(5), pp.513-7 [Peer Reviewed Journal]

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18
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The Discovery of MK-4256, a Potent SSTR3 Antagonist as a Potential Treatment of Type 2 Diabetes

He, Shuwen ; Ye, Zhixiong ; Truong, Quang ; Shah, Shrenik ; Du, Wu ; Guo, Liangqin ; Dobbelaar, Peter H ; Lai, Zhong ; Liu, Jian ; Jian, Tianying ; Qi, Hongbo ; Bakshi, Raman K ; Hong, Qingmei ; Dellureficio, James ; Pasternak, Alexander ; Feng, Zhe ; Dejesus, Reynalda ; Yang, Lihu ; Reibarkh, Mikhail ; Bradley, Scott A ; Holmes, Mark A ; Ball, Richard G ; Ruck, Rebecca T ; Huffman, Mark A ; Wong, Frederick ; Samuel, Koppara ; Reddy, Vijay B ; Mitelman, Stan ; Tong, Sharon X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Wu, Margaret ; Shao, Qing ; Trujillo, Maria E ; Eiermann, George J ; Li, Cai ; Zhang, Bei B ; Howard, Andrew D ; Zhou, Yun-Ping ; Nargund, Ravi P ; Hagmann, William K

ACS medicinal chemistry letters, 14 June 2012, Vol.3(6), pp.484-9 [Peer Reviewed Journal]

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19
Structural Optimization Affording 2-( R )-(1-( R )-3,5-Bis(trifluoromethyl)phenylethoxy)-3-( S )-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist
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Structural Optimization Affording 2-( R )-(1-( R )-3,5-Bis(trifluoromethyl)phenylethoxy)-3-( S )-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist

Hale, Jeffrey J. ; Mills, Sander G. ; Maccoss, Malcolm ; Finke, Paul E. ; Cascieri, Margaret A. ; Sadowski, Sharon ; Ber, Elzbieta ; Chicchi, Gary G. ; Kurtz, Marc ; Metzger, Joseph ; Eiermann, George ; Tsou, Nancy N. ; Tattersall, F. David ; Rupniak, Nadia M. J. ; Williams, Angela R. ; Rycroft, Wayne ; Hargreaves, Richard ; Macintyre, D. Euan

Journal of Medicinal Chemistry, 11/1998, Vol.41(23), pp.4607-4614 [Peer Reviewed Journal]

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20
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1-Phenyl-8-azabicyclo[3.2.1]octane ethers: A novel series of neurokinin (NK 1) antagonists

Huscroft, Ian T ; Carlson, Emma J ; Chicchi, Gary G ; Kurtz, Marc M ; London, Clare ; Raubo, Piotr ; Wheeldon, Alan ; Kulagowski, Janusz J

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(7), pp.2008-2012 [Peer Reviewed Journal]

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21
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Synthesis and structure–activity relationships of 8-azabicyclo[3.2.1]octane benzylamine NK 1 antagonists

Thomson, Christopher G ; Carlson, Emma ; Chicchi, Gary G ; Kulagowski, Janusz J ; Kurtz, Marc M ; Swain, Christopher J ; Tsao, Kwei-Lan C ; Wheeldon, Alan

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(4), pp.811-814 [Peer Reviewed Journal]

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22
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Identification, localization and receptor characterization of novel mammalian substance P-like peptides

Kurtz, Marc M ; Wang, Ruiping ; Clements, Michelle K ; Cascieri, Margaret A ; Austin, Christopher P ; Cunningham, Barry R ; Chicchi, Gary G ; Liu, Qingyun

Gene, 21 August 2002, Vol.296(1-2), pp.205-212 [Peer Reviewed Journal]

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23
Phosphorylated Morpholine Acetal Human Neurokinin-1 Receptor Antagonists as Water-Soluble Prodrugs
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Phosphorylated Morpholine Acetal Human Neurokinin-1 Receptor Antagonists as Water-Soluble Prodrugs

Hale, Jeffrey J. ; Mills, Sander G. ; Maccoss, Malcolm ; Dorn, Conrad P. ; Finke, Paul E. ; Budhu, Richard J. ; Reamer, Robert A. ; Huskey, Su-Er W. ; Luffer-Atlas, Debra ; Dean, Brian J. ; Mcgowan, Erin M. ; Feeney, William P. ; Chiu, Shuet-Hing Lee ; Cascieri, Margaret A. ; Chicchi, Gary G. ; Kurtz, Marc M. ; Sadowski, Sharon ; Ber, Elzbieta ; Tattersall, F. David ; Rupniak, Nadia M. J. ; Williams, Angela R. ; Rycroft, Wayne ; Hargreaves, Richard ; Metzger, Joseph M. ; Macintyre, D. Euan

Journal of Medicinal Chemistry, 03/2000, Vol.43(6), pp.1234-1241 [Peer Reviewed Journal]

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24
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Pyrrolidine-carboxamides and oxadiazoles as potent hNK 1 antagonists

Young, Jonathan R ; Eid, Ronsar ; Turner, Cherilyn ; Devita, Robert J ; Kurtz, Marc M ; Tsao, Kwei-Lan C ; Chicchi, Gary G ; Wheeldon, Alan ; Carlson, Emma ; Mills, Sander G

Bioorganic & Medicinal Chemistry Letters, 2007, Vol.17(19), pp.5310-5315 [Peer Reviewed Journal]

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25
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NK 1 antagonists based on seven membered lactam scaffolds

Elliott, Jason M ; Carlson, Emma J ; Chicchi, Gary G ; Dirat, Olivier ; Dominguez, Maria ; Gerhard, Ute ; Jelley, Richard ; Jones, A. Brian ; Kurtz, Marc M ; Tsao, Kwei Lan ; Wheeldon, Alan

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(11), pp.2929-2932 [Peer Reviewed Journal]

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26
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Cyclopentane-based human NK1 antagonists. Part 1: Discovery and initial SAR

Finke, Paul E ; Meurer, Laura C ; Levorse, Dorothy A ; Mills, Sander G ; Maccoss, Malcolm ; Sadowski, Sharon ; Cascieri, Margaret A ; Tsao, Kwei-Lan ; Chicchi, Gary G ; Metzger, Joseph M ; Macintyre, D. Euan

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(17), pp.4497-4503 [Peer Reviewed Journal]

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27
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Spirocyclic NK 1 antagonists II: [4.5]-spiroethers

Williams, Brian J ; Cascieri, Margaret A ; Chicchi, Gary G ; Harrison, Timothy ; Owens, Andrew P ; Owen, Simon N ; Rupniak, Nadia M.J ; Tattersall, David F ; Williams, Angela ; Swain, Christopher J

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(19), pp.2719-2722 [Peer Reviewed Journal]

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28
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2-Aryl indole NK 1 antagonists: optimisation of the amide substituent

Shaw, Duncan ; Chicchi, Gary G ; Elliott, Jason M ; Kurtz, Marc ; Morrison, Denise ; Ridgill, Mark P ; Szeto, Nicola ; Watt, Alan P ; Williams, Angela R ; Swain, Christopher J

Bioorganic & Medicinal Chemistry Letters, 2001, Vol.11(23), pp.3031-3034 [Peer Reviewed Journal]

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29
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2-Aryl indole NK 1 receptor antagonists: optimisation of the 2-Aryl ring and the indole nitrogen substituent

Dinnell, Kevin ; Chicchi, Gary G ; Dhar, Madhumeeta J ; Elliott, Jason M ; Hollingworth, Gregory J ; Kurtz, Marc M ; Ridgill, Mark P ; Rycroft, Wayne ; Tsao, Kwei-Lan ; Williams, Angela R ; Swain, Christopher J

Bioorganic & Medicinal Chemistry Letters, 2001, Vol.11(9), pp.1237-1240 [Peer Reviewed Journal]

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30
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(Thr-59)-insulin-like growth factor I stimulates 2-deoxyglucose transport in BC3H1 myocytes through the insulin-like growth factor receptor, not the insulin receptor

Cascieri, Margaret A ; Chicchi, Gary G ; Hayes, Nancy S ; Strader, Catherine D

BBA - Molecular Cell Research, 1986, Vol.886(3), pp.491-499 [Peer Reviewed Journal]

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31
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The discovery of potent, selective, and orally bioavailable hNK 1 antagonists derived from pyrrolidine

Lin, Peter ; Chang, Lehua ; Devita, Robert J ; Young, Jonathan R ; Eid, Ronsar ; Tong, Xinchun ; Zheng, Song ; Ball, Richard G ; Tsou, Nancy N ; Chicchi, Gary G ; Kurtz, Marc M ; Tsao, Kwei-Lan C ; Wheeldon, Alan ; Carlson, Emma J ; Eng, Waisi ; Burns, H. Donald ; Hargreaves, Richard J ; Mills, Sander G

Bioorganic & Medicinal Chemistry Letters, 2007, Vol.17(18), pp.5191-5198 [Peer Reviewed Journal]

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32
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N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists

Elliott, Jason M ; Carling, Robert W ; Chambers, Mark ; Chicchi, Gary G ; Hutson, Peter H ; Jones, A Brian ; Macleod, Angus ; Marwood, Rose ; Meneses-Lorente, Georgina ; Mezzogori, Elena ; Murray, Fraser ; Rigby, Michael ; Royo, Inmaculada ; Russell, Michael G N ; Sohal, Bindi ; Tsao, Kwei Lan ; Williams, Brian

Bioorganic & medicinal chemistry letters, 15 November 2006, Vol.16(22), pp.5748-51 [Peer Reviewed Journal]

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33
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N′,2-Diphenylquinoline-4-carbohydrazide based NK 3 receptor antagonists II

Elliott, Jason M ; Carling, Robert W ; Chicchi, Gary G ; Crawforth, James ; Hutson, Peter H ; Jones, A. Brian ; Kelly, Sarah ; Marwood, Rose ; Meneses-Lorente, Georgina ; Mezzogori, Elena ; Murray, Fraser ; Rigby, Michael ; Royo, Inmaculada ; Russell, Michael G.N ; Shaw, Duncan ; Sohal, Bindi ; Tsao, Kwei Lan ; Williams, Brian

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(22), pp.5752-5756 [Peer Reviewed Journal]

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34
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N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists II

Elliott, Jason M ; Carling, Robert W ; Chicchi, Gary G ; Crawforth, James ; Hutson, Peter H ; Jones, A Brian ; Kelly, Sarah ; Marwood, Rose ; Meneses-Lorente, Georgina ; Mezzogori, Elena ; Murray, Fraser ; Rigby, Michael ; Royo, Inmaculada ; Russell, Michael G N ; Shaw, Duncan ; Sohal, Bindi ; Tsao, Kwei Lan ; Williams, Brian

Bioorganic & medicinal chemistry letters, 15 November 2006, Vol.16(22), pp.5752-6 [Peer Reviewed Journal]

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35
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Novel lactam NK 1 antagonists with anti-emetic activity

Hollingworth, Gregory J ; Carlson, Emma J ; Castro, José L ; Chicchi, Gary G ; Clark, Natalie ; Cooper, Laura C ; Dirat, Olivier ; Salvo, Jerry Di ; Elliott, Jason M ; Kilburn, Ruth ; Kurtz, Marc M ; Rycroft, Wayne ; Tattersall, F. David ; Tsao, Kwei-Lan ; Swain, Christopher J

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(5), pp.1197-1201 [Peer Reviewed Journal]

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36
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N′,2-Diphenylquinoline-4-carbohydrazide based NK 3 receptor antagonists

Elliott, Jason M ; Carling, Robert W ; Chambers, Mark ; Chicchi, Gary G ; Hutson, Peter H ; Jones, A. Brian ; Macleod, Angus ; Marwood, Rose ; Meneses-Lorente, Georgina ; Mezzogori, Elena ; Murray, Fraser ; Rigby, Michael ; Royo, Inmaculada ; Russell, Michael G.N ; Sohal, Bindi ; Tsao, Kwei Lan ; Williams, Brian

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(22), pp.5748-5751 [Peer Reviewed Journal]

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