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21 Results  for Everything (Includes Articles)

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Nucleoside optimization for RNAi: a high-throughput platform

Butora, Gabor ; Kenski, Denise M ; Cooper, Abby J ; Fu, Wenlang ; Qi, Ning ; Li, Jenny J ; Flanagan, W Michael ; Davies, Ian W

Journal of the American Chemical Society, 26 October 2011, Vol.133(42), pp.16766-9 [Peer Reviewed Journal]

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Cyclic‐Disulfide‐Based Prodrugs for Cytosol‐Specific Drug Delivery

Butora, Gabor ; Qi, Ning ; Fu, Wenlang ; Nguyen, Truyen ; Huang, Hsueh‐Cheng ; Davies, Ian W.

Angewandte Chemie International Edition, 15 December 2014, Vol.53(51), pp.14046-14050 [Peer Reviewed Journal]

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Cyclic-Disulfide-Based Prodrugs for Cytosol-Specific Drug Delivery

Butora, Gabor ; Qi, Ning ; Fu, Wenlang ; Nguyen, Truyen ; Huang, Hsueh-Cheng ; Davies, Ian W

Angewandte Chemie, Dec 15, 2014, Vol.126(51), pp.14270-14274 [Peer Reviewed Journal]

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Cyclic‐Disulfide‐Based Prodrugs for Cytosol‐Specific Drug Delivery

Butora, Gabor ; Qi, Ning ; Fu, Wenlang ; Nguyen, Truyen ; Huang, Hsueh‐Cheng ; Davies, Ian W.

Angewandte Chemie, 15 December 2014, Vol.126(51), pp.14270-14274 [Peer Reviewed Journal]

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Concise preparation of 8-trifluoromethyltetrahydro-6 H-pyrido [1,2- a] pyrazine-6-one

Kothandaraman, Shankaran ; Guiadeen, Deodialsingh ; Butora, Gabor ; Doss, George ; Mills, Sander G ; Maccoss, Malcolm ; Yang, Lihu

Tetrahedron Letters, 2009, Vol.50(28), pp.4050-4053 [Peer Reviewed Journal]

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Post-Synthetic Modification of Oligonucleotides via Orthogonal Amidation and Copper Catalyzed Cycloaddition Reactions

Zewge, Daniel ; Butora, Gabor ; Sherer, Edward C ; Tellers, David M ; Sidler, Daniel R ; Gouker, Joseph ; Copeland, Greg ; Jadhav, Vasant ; Li, Zhen ; Armstrong, Joseph ; Davies, Ian W

Bioconjugate chemistry, 20 June 2018, Vol.29(6), pp.1859-1865 [Peer Reviewed Journal]

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siRNA-optimized Modifications for Enhanced In Vivo Activity

Kenski, Denise M ; Butora, Gabor ; Willingham, Aarron T ; Cooper, Abby J ; Fu, Wenlang ; Qi, Ning ; Soriano, Ferdie ; Davies, Ian W ; Flanagan, W Michael

Molecular Therapy - Nucleic Acids, 2012, Vol.1, p.e5 [Peer Reviewed Journal]

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Chemoenzymatic and electrochemical oxidations in the synthesis of octahydroisoquinolines for conversion to morphine. Relative merits of radical vs. acid-catalyzed cyclizations

Endoma, Mary Ann ; Butora, Gabor ; Claeboe, Christopher D ; Hudlicky, Tomas ; Abboud, Khalil A

Tetrahedron Letters, 1997, Vol.38(51), pp.8833-8836 [Peer Reviewed Journal]

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The elusive 8-fluoroadenosine: a simple non-enzymatic synthesis and characterization

Butora, Gabor ; Schmitt, Christoph ; Levorse, Dorothy A ; Streckfuss, Eric ; Doss, George A ; Maccoss, Malcolm

Tetrahedron, 2007, Vol.63(18), pp.3782-3789 [Peer Reviewed Journal]

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Electrochemical versus Anionic Oxygenation of Azathymine Derivatives
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Electrochemical versus Anionic Oxygenation of Azathymine Derivatives

Butora, Gabor ; Reed, Josephine W. ; Hudlicky, Tomas ; Brammer, Larry E. ; Higgs, Paul I. ; Simmons, Dana P. ; Heard, Nina E.

Journal of the American Chemical Society, 08/1997, Vol.119(33), pp.7694-7701 [Peer Reviewed Journal]

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Synthesis of 2′-β- C-methyl-neplanocin derivatives as anti-HCV agents

Liao, Xibin ; Butora, Gabor ; Olsen, David B ; Carroll, Steven S ; Mcmasters, Daniel R ; Leone, Joseph F ; Stahlhut, Mark ; Doss, George A ; Yang, Lihu ; Maccoss, Malcolm

Tetrahedron Letters, 2008, Vol.49(26), pp.4149-4152 [Peer Reviewed Journal]

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New chiral synthons from the microbial oxidation of bromonaphthalenes

Hudlicky, Tomas ; Endoma, Mary Ann A ; Butora, Gabor

Tetrahedron: Asymmetry, 1996, Vol.7(1), pp.61-68 [Peer Reviewed Journal]

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Chemoenzymatic synthesis of the morphine skeleton via radical cyclization and a C 10C 11 closure

Butora, Gabor ; Hudlicky, Tomas ; Fearnley, Stephen P ; Gum, Andrew G ; Stabile, Michele R ; Abboud, Khalil

Tetrahedron Letters, 1996, Vol.37(45), pp.8155-8158 [Peer Reviewed Journal]

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Use of Electrochemical Methods as an Alternative to Tin Reagents for the Reduction of Vinyl Halides in Inositol Synthons

Hudlicky, Tomas ; Claeboe, Christopher D ; Brammer, Larry E ; Koroniak, Lukasz ; Butora, Gabor ; Ghiviriga, Ion

The Journal of organic chemistry, 25 June 1999, Vol.64(13), pp.4909-4913 [Peer Reviewed Journal]

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15
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Synthesis and HCV inhibitory properties of 9-deaza- and 7,9-dideaza-7-oxa-2′- C-methyladenosine

Butora, Gabor ; Olsen, David B ; Carroll, Steven S ; Mcmasters, Daniel R ; Schmitt, Christoph ; Leone, Joseph F ; Stahlhut, Mark ; Burlein, Christine ; Maccoss, Malcolm

Bioorganic & Medicinal Chemistry, 2007, Vol.15(15), pp.5219-5229 [Peer Reviewed Journal]

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Discovery of 3-piperidinyl-1-cyclopentanecarboxamide as a novel scaffold for highly potent CC chemokine receptor 2 antagonists

Yang, Lihu ; Butora, Gabor ; Jiao, Richard X ; Pasternak, Alex ; Zhou, Changyou ; Parsons, William H ; Mills, Sander G ; Vicario, Pasquale P ; Ayala, Julia M ; Cascieri, Margaret A ; Maccoss, Malcolm

Journal of medicinal chemistry, 31 May 2007, Vol.50(11), pp.2609-11 [Peer Reviewed Journal]

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17
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3-Amino-1-alkyl-cyclopentane carboxamides as small molecule antagonists of the human and murine CC chemokine receptor 2

Butora, Gabor ; Jiao, Richard ; Parsons, William H ; Vicario, Pasquale P ; Jin, Hong ; Ayala, Julia M ; Cascieri, Margaret A ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 2007, Vol.17(13), pp.3636-3641 [Peer Reviewed Journal]

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Conformational studies of 3-amino-1-alkyl-cyclopentane carboxamide CCR2 antagonists leading to new spirocyclic antagonists

Pasternak, Alexander ; Goble, Stephen D ; Doss, George A ; Tsou, Nancy N ; Butora, Gabor ; Vicario, Pasquale P ; Ayala, Julia Marie ; Struthers, Mary ; Demartino, Julie A ; Mills, Sander G ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 2008, Vol.18(4), pp.1374-1377 [Peer Reviewed Journal]

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4-Amino-2-alkyl-butyramides as small molecule CCR2 antagonists with favorable pharmacokinetic properties

Butora, Gabor ; Morriello, Gregori J ; Kothandaraman, Shankaran ; Guiadeen, Deodialsingh ; Pasternak, Alexander ; Parsons, William H ; Maccoss, Malcolm ; Vicario, Pasquale P ; Cascieri, Margaret A ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 15 September 2006, Vol.16(18), pp.4715-4722 [Peer Reviewed Journal]

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20
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Design, synthesis, and structure–activity relationship of novel CCR2 antagonists

Kothandaraman, Shankaran ; Donnely, Karla L ; Butora, Gabor ; Jiao, Richard ; Pasternak, Alexander ; Morriello, Gregori J ; Goble, Stephen D ; Zhou, Changyou ; Mills, Sander G ; Maccoss, Malcolm ; Vicario, Pasquale P ; Ayala, Julia M ; Demartino, Julie A ; Struthers, Mary ; Cascieri, Margaret A ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(6), pp.1830-1834 [Peer Reviewed Journal]

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Discovery of 3,5-bis(trifluoromethyl)benzyl l-arylglycinamide based potent CCR2 antagonists

Yang, Lihu ; Zhou, Changyou ; Guo, Liangqin ; Morriello, Gregori ; Butora, Gabor ; Pasternak, Alexander ; Parsons, William H ; Mills, Sander G ; Maccoss, Malcolm ; Vicario, Pasquale P ; Zweerink, Hans ; Ayala, Julia M ; Goyal, Shefali ; Hanlon, William A ; Cascieri, Margaret A ; Springer, Marty S

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(14), pp.3735-3739 [Peer Reviewed Journal]

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