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12 Results  for Everything (Includes Articles)

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1
Discovery of a Potent and Orally Bioavailable CCR2 and CCR5 Dual Antagonist
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Discovery of a Potent and Orally Bioavailable CCR2 and CCR5 Dual Antagonist

Pasternak, Alexander ; Goble, Stephen D. ; Struthers, Mary ; Vicario, Pasquale P. ; Ayala, Julia M. ; Di Salvo, Jerry ; Kilburn, Ruth ; Wisniewski, Thomas ; Demartino, Julie A. ; Mills, Sander G. ; Yang, Lihu

ACS Medicinal Chemistry Letters, 04/08/2010, Vol.1(1), pp.14-18 [Peer Reviewed Journal]

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Discovery of 3-piperidinyl-1-cyclopentanecarboxamide as a novel scaffold for highly potent CC chemokine receptor 2 antagonists

Yang, Lihu ; Butora, Gabor ; Jiao, Richard X ; Pasternak, Alex ; Zhou, Changyou ; Parsons, William H ; Mills, Sander G ; Vicario, Pasquale P ; Ayala, Julia M ; Cascieri, Margaret A ; Maccoss, Malcolm

Journal of medicinal chemistry, 31 May 2007, Vol.50(11), pp.2609-11 [Peer Reviewed Journal]

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3
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CCR5 blockade modulates inflammation and alloimmunity in primates

Schröder, Carsten ; Pierson, Richard N ; Nguyen, Bao-Ngoc H ; Kawka, Douglas W ; Peterson, Laurence B ; Wu, Guosheng ; Zhang, Tianshu ; Springer, Martin S ; Siciliano, Sal J ; Iliff, Susan ; Ayala, Julia M ; Lu, Min ; Mudgett, John S ; Lyons, Kathy ; Mills, Sander G ; Miller, Geraldine G ; Singer, Irwin I ; Azimzadeh, Agnes M ; Demartino, Julie A

Journal of immunology (Baltimore, Md. : 1950), 15 August 2007, Vol.179(4), pp.2289-99 [Peer Reviewed Journal]

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Enzymatically Inactive Macrophage Migration Inhibitory Factor Inhibits Monocyte Chemotaxis and Random Migration †
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Enzymatically Inactive Macrophage Migration Inhibitory Factor Inhibits Monocyte Chemotaxis and Random Migration †

Hermanowski-Vosatka, Anne ; Mundt, Steven S. ; Ayala, Julia M. ; Goyal, Shefali ; Hanlon, William A. ; Czerwinski, Robert M. ; Wright, Samuel D. ; Whitman, Christian P.

Biochemistry, 09/1999, Vol.38(39), pp.12841-12849 [Peer Reviewed Journal]

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5
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3-Amino-1-alkyl-cyclopentane carboxamides as small molecule antagonists of the human and murine CC chemokine receptor 2

Butora, Gabor ; Jiao, Richard ; Parsons, William H ; Vicario, Pasquale P ; Jin, Hong ; Ayala, Julia M ; Cascieri, Margaret A ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 2007, Vol.17(13), pp.3636-3641 [Peer Reviewed Journal]

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6
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Use of an antibody against the matrix metalloproteinase–generated aggrecan neoepitope fvdipen‐cooh to assess the effects of stromelysin in a rabbit model of cartilage degradation

Bayne, Ellen Kahn ; Macnaul, Karen L. ; Donatelli, Susan A. ; Christen, Amy ; Griffin, Patrick R. ; Hoerrner, Lori A. ; Calaycay, Jimmy R. ; Ayala, Julia M. ; Chapman, Kevin ; Hagmann, William ; Weidner, Jeffrey R. ; Mcdonnell, Joseph ; Moore, Vernon L. ; Mumford, Richard A. ; Lark, Michael W. ; Hutchinson, Nancy I.

Arthritis & Rheumatism, October 1995, Vol.38(10), pp.1400-1409 [Peer Reviewed Journal]

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7
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Potent heteroarylpiperidine and carboxyphenylpiperidine 1-alkyl-cyclopentane carboxamide CCR2 antagonists

Pasternak, Alexander ; Goble, Stephen D ; Vicario, Pasquale P ; Di Salvo, Jerry ; Ayala, Julia M ; Struthers, Mary ; Demartino, Julie A ; Mills, Sander G ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 2008, Vol.18(3), pp.994-998 [Peer Reviewed Journal]

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8
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Leukotriene B4 strongly increases monocyte chemoattractant protein-1 in human monocytes

Huang, Li ; Zhao, Annie ; Wong, Frederick ; Ayala, Julia M ; Struthers, Mary ; Ujjainwalla, Feroze ; Wright, Samuel D ; Springer, Marty S ; Evans, Jilly ; Cui, Jisong

Arteriosclerosis, thrombosis, and vascular biology, October 2004, Vol.24(10), pp.1783-8 [Peer Reviewed Journal]

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9
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Design, synthesis, and structure–activity relationship of novel CCR2 antagonists

Kothandaraman, Shankaran ; Donnely, Karla L ; Butora, Gabor ; Jiao, Richard ; Pasternak, Alexander ; Morriello, Gregori J ; Goble, Stephen D ; Zhou, Changyou ; Mills, Sander G ; Maccoss, Malcolm ; Vicario, Pasquale P ; Ayala, Julia M ; Demartino, Julie A ; Struthers, Mary ; Cascieri, Margaret A ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(6), pp.1830-1834 [Peer Reviewed Journal]

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10
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Diaryl substituted pyrazoles as potent CCR2 receptor antagonists

Pinkerton, Anthony B ; Huang, Dehua ; Cube, Rowena V ; Hutchinson, John H ; Struthers, Mary ; Ayala, Julia M ; Vicario, Pasquale P ; Patel, Sima R ; Wisniewski, Thomas ; Demartino, Julie A ; Vernier, Jean-Michel

Bioorganic & Medicinal Chemistry Letters, 2007, Vol.17(3), pp.807-813 [Peer Reviewed Journal]

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11
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Endopeptidase-24.15 in rat hypothalamic/pituitary/gonadal axis

Pierotti, Adrian R ; Lasdun, Abraham ; Ayala, Julia M ; Roberts, James L ; Molineaux, Christopher J

Molecular and Cellular Endocrinology, 1991, Vol.76(1), pp.95-103 [Peer Reviewed Journal]

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Discovery of 3,5-bis(trifluoromethyl)benzyl l-arylglycinamide based potent CCR2 antagonists

Yang, Lihu ; Zhou, Changyou ; Guo, Liangqin ; Morriello, Gregori ; Butora, Gabor ; Pasternak, Alexander ; Parsons, William H ; Mills, Sander G ; Maccoss, Malcolm ; Vicario, Pasquale P ; Zweerink, Hans ; Ayala, Julia M ; Goyal, Shefali ; Hanlon, William A ; Cascieri, Margaret A ; Springer, Marty S

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(14), pp.3735-3739 [Peer Reviewed Journal]

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