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Polymer–Peptide Conjugates Disassemble Amyloid β Fibrils in a Molecular-Weight Dependent Manner

Song, Yang ; Moore, Edwin G ; Guo, Yanshu ; Moore, Jeffrey S Univ. of Illinois At Urbana-Champaign, Il (United States) (Corporate Author)

Journal of the American Chemical Society, 14 March 2017, Vol.139(12) [Peer Reviewed Journal]

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Crystal structure of the adenosine A 2A receptor bound to an antagonist reveals a potential allosteric pocket

Sun, Bingfa ; Bachhawat, Priti ; Chu, Matthew Ling-Hon ; Wood, Martyn ; Ceska, Tom ; Sands, Zara A ; Mercier, Joel ; Lebon, Florence ; Kobilka, Tong Sun ; Kobilka, Brian K Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Proceedings of the National Academy of Sciences of the United States of America, 06 February 2017, Vol.114(8) [Peer Reviewed Journal]

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Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody

Raymond, Donald D ; Bajic, Goran ; Ferdman, Jack ; Suphaphiphat, Pirada ; Settembre, Ethan C ; Moody, M. Anthony ; Schmidt, Aaron G ; Harrison, Stephen C Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Proceedings of the National Academy of Sciences of the United States of America, 18 December 2017, Vol.115(1) [Peer Reviewed Journal]

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Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome

Ferrari, Michele ; Jain, Isha H ; Goldberger, Olga ; Rezoagli, Emanuele ; Thoonen, Robrecht ; Cheng, Kai-Hung ; Sosnovik, David E ; Scherrer-Crosbie, Marielle ; Mootha, Vamsi K ; Zapol, Warren M Krell Inst., Ames, Ia (United States) (Corporate Author)

Proceedings of the National Academy of Sciences of the United States of America, 08 May 2017, Vol.114(21) [Peer Reviewed Journal]

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Structural basis for Notch1 engagement of Delta-like 4

Luca, Vincent C ; Jude, Kevin M ; Pierce, Nathan W ; Nachury, Maxence V ; Fischer, Suzanne ; Garcia, K. Christopher Argonne National Lab. (Anl), Argonne, Il (United States) (Corporate Author)

Science, 20 February 2015, Vol.347(6224) [Peer Reviewed Journal]

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Structure and membrane remodeling activity of ESCRT-III helical polymers

Mccullough, John ; Clippinger, Amy K ; Talledge, Nathaniel ; Skowyra, Michael L ; Saunders, Marissa G ; Naismith, Teresa V ; Colf, Leremy A ; Afonine, Pavel ; Arthur, Christopher ; Sundquist, Wesley I ; Hanson, Phyllis I ; Frost, Adam Lawrence Berkeley National Lab. (Lbnl), Berkeley, Ca (United States) (Corporate Author)

Science, 18 December 2015, Vol.350(6267) [Peer Reviewed Journal]

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OCO-2 advances photosynthesis observation from space via solar-induced chlorophyll fluorescence

Sun, Ying ; Frankenberg, C ; Wood, Jeff D ; Schimel, David S ; Jung, M ; Guanter, L ; Drewry, D. T ; Verma, M ; Porcar-Castell, A ; Griffis, T. J ; Gu, Lianhong ; Magney, T. S ; Köhler, P ; Evans, B ; Yuen, K Oak Ridge National Lab. (Ornl), Oak Ridge, Tn (United States) (Corporate Author)

Science, 12 October 2017, Vol.358(6360) [Peer Reviewed Journal]

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X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability

Gres, Anna T ; Kirby, Karen A ; Kewalramani, Vineet N ; Tanner, John J ; Pornillos, Owen ; Sarafianos, Stefan G Univ. of Missouri, Columbia, Mo (United States) (Corporate Author)

Science, 04 June 2015, Vol.349(6243) [Peer Reviewed Journal]

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Structural principles of distinct assemblies of the human α4β2 nicotinic receptor

Walsh, Jr., Richard M ; Roh, Soung -Hun ; Gharpure, Anant ; Morales-Perez, Claudio L ; Teng, Jinfeng ; Hibbs, Ryan E Slac National Accelerator Lab., Menlo Park, Ca (United States) (Corporate Author)

Nature (London), 02 May 2018, Vol.557(7704) [Peer Reviewed Journal]

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The heat released during catalytic turnover enhances the diffusion of an enzyme

Riedel, Clement ; Gabizon, Ronen ; Wilson, Christian A. M ; Hamadani, Kambiz ; Tsekouras, Konstantinos ; Marqusee, Susan ; Pressé, Steve ; Bustamante, Carlos Lawrence Berkeley National Lab. (Lbnl), Berkeley, Ca (United States) (Corporate Author)

Nature (London), 10 December 2014, Vol.517(7533) [Peer Reviewed Journal]

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11
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Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

Kong, Rui ; Xu, Kai ; Zhou, Tongqing ; Acharya, Priyamvada ; Lemmin, Thomas ; Liu, Kevin ; Ozorowski, Gabriel ; Soto, Cinque ; Taft, Justin D ; Bailer, Robert T ; Cale, Evan M ; Chen, Lei ; Choi, Chang W ; Chuang, Gwo-Yu ; Doria-Rose, Nicole A ; Druz, Aliaksandr ; Georgiev, Ivelin S ; Gorman, Jason ; Huang, Jinghe ; Joyce, M. Gordon ; Louder, Mark K ; Ma, Xiaochu ; Mckee, Krisha ; O'Dell, Sijy ; Pancera, Marie ; Yang, Yongping ; Blanchard, Scott C ; Mothes, Walther ; Burton, Dennis R ; Koff, Wayne C ; Connors, Mark ; Ward, Andrew B ; Kwong, Peter D ; Mascola, John R National Inst. of Health (NIH), Bethesda, MD (United States) (Corporate Author)

Science, 13 May 2016, Vol.352(6287) [Peer Reviewed Journal]

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12
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Structural basis for histone H2B deubiquitination by the SAGA DUB module

Morgan, Michael T ; Haj-Yahya, Mahmood ; Ringel, Alison E ; Bandi, Prasanthi ; Brik, Ashraf ; Wolberger, Cynthia Johns Hopkins Univ., Baltimore, MD (United States) (Corporate Author)

Science, 12 February 2016, Vol.351(6274) [Peer Reviewed Journal]

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13
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Using ancient protein kinases to unravel a modern cancer drug's mechanism

Wilson, C ; Agafonov, R. V ; Hoemberger, M ; Kutter, S ; Zorba, A ; Halpin, J ; Buosi, V ; Otten, R ; Waterman, D ; Theobald, D. L ; Kern, D Brandeis Univ., Waltham, MA (United States) (Corporate Author)

Science, 19 February 2015, Vol.347(6224) [Peer Reviewed Journal]

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14
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Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome

Gagnon, M. G ; Lin, J ; Bulkley, D ; Steitz, T. A Brookhaven National Laboratory (Bnl), Upton, Ny (United States) (Corporate Author)

Science, 08 August 2014, Vol.345(6197) [Peer Reviewed Journal]

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15
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Eye patches: Protein assembly of index-gradient squid lenses

Cai, J ; Townsend, J. P ; Dodson, T. C ; Heiney, P. A ; Sweeney, A. M Brookhaven National Laboratory (Bnl), Upton, Ny (United States) (Corporate Author)

Science, 10 August 2017, Vol.357(6351) [Peer Reviewed Journal]

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16
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Design of structurally distinct proteins using strategies inspired by evolution

Jacobs, T. M ; Williams, B ; Williams, T ; Xu, X ; Eletsky, A ; Federizon, J. F ; Szyperski, T ; Kuhlman, B Univ. of North Carolina, Chapel Hill, NC (United States) (Corporate Author) ; Univ. At Buffalo, Ny (United States) (Corporate Author)

Science, 06 May 2016, Vol.352(6286) [Peer Reviewed Journal]

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17
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Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions

Jiang, Jiansen ; Chan, Henry ; Cash, Darian D ; Miracco, Edward J ; Ogorzalek Loo, Rachel R ; Upton, Heather E ; Cascio, Duilio ; O'Brien Johnson, Reid ; Collins, Kathleen ; Loo, Joseph A ; Zhou, Z. Hong ; Feigon, Juli Univ. of California, Los Angeles, Ca (United States) (Corporate Author)

Science, 15 October 2015, Vol.350(6260) [Peer Reviewed Journal]

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18
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HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

Jardine, Joseph G ; Kulp, Daniel W ; Havenar-Daughton, Colin ; Sarkar, Anita ; Briney, Bryan ; Sok, Devin ; Sesterhenn, Fabian ; Ereno-Orbea, June ; Kalyuzhniy, Oleksandr ; Deresa, Isaiah ; Hu, Xiaozhen ; Spencer, Skye ; Jones, Meaghan ; Georgeson, Erik ; Adachi, Yumiko ; Kubitz, Michael ; Decamp, Allan C ; Julien, Jean -Philippe ; Wilson, Ian A ; Burton, Dennis R ; Crotty, Shane ; Schief, William R Scripps Research Inst., La Jolla, Ca (United States) (Corporate Author)

Science, 25 March 2016, Vol.351(6280) [Peer Reviewed Journal]

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19
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Structural basis for microRNA targeting

Schirle, Nicole T ; Sheu-Gruttadauria, Jessica ; Macrae, Ian J The Scripps Research Inst., La Jolla, Ca (United States) (Corporate Author)

Science, 31 October 2014, Vol.346(6209) [Peer Reviewed Journal]

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20
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Potential mechanisms for cancer resistance in elephants and comparative cellular response to DNA damage in humans

Abegglen, Lisa M ; Caulin, Aleah F ; Chan, Ashley ; Lee, Kristy ; Robinson, Rosann ; Campbell, Michael S ; Kiso, Wendy K ; Schmitt, Dennis L ; Waddell, Peter J ; Bhaskara, Srividya ; Jensen, Shane T ; Maley, Carlo C ; Schiffman, Joshua D Univ. of Utah, Salt Lake City, Ut (United States) (Corporate Author)

JAMA, Journal of the American Medical Association, 08 October 2015, Vol.314(17) [Peer Reviewed Journal]

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21
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Living liquid crystals

Zhou, S ; Sokolov, A ; Lavrentovich, O. D ; Aranson, I. S Argonne National Lab. (Anl), Argonne, Il (United States) (Corporate Author)

Proceedings of the National Academy of Sciences of the United States of America, 13 January 2014, Vol.111(4) [Peer Reviewed Journal]

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22
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An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling

Kim, Sun Kyung ; Barron, Lindsey ; Hinck, Cynthia S ; Petrunak, Elyse M ; Cano, Kristin E ; Thangirala, Avinash ; Iskra, Brian ; Brothers, Molly ; Vonberg, Machell ; Leal, Belinda ; Richter, Blair ; Kodali, Ravindra ; Taylor, Alexander B ; Du, Shoucheng ; Barnes, Christopher O ; Sulea, Traian ; Calero, Guillermo ; Hart, P. John ; Hart, Matthew J ; Demeler, Borries ; Hinck, Andrew P Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Journal of Biological Chemistry, 22 February 2017, Vol.292(17) [Peer Reviewed Journal]

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23
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Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists

Zheng, Yi ; Qin, Ling ; Zacarías, Natalia V. Ortiz ; de Vries, Henk ; Han, Gye Won ; Gustavsson, Martin ; Dabros, Marta ; Zhao, Chunxia ; Cherney, Robert J ; Carter, Percy ; Stamos, Dean ; Abagyan, Ruben ; Cherezov, Vadim ; Stevens, Raymond C ; Ijzerman, Adriaan P ; Heitman, Laura H ; Tebben, Andrew ; Kufareva, Irina ; Handel, Tracy M Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Nature (London), 07 December 2016, Vol.540(7633) [Peer Reviewed Journal]

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24
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Structural basis for selectivity and diversity in angiotensin II receptors

Zhang, Haitao ; Han, Gye Won ; Batyuk, Alexander ; Ishchenko, Andrii ; White, Kate L ; Patel, Nilkanth ; Sadybekov, Anastasiia ; Zamlynny, Beata ; Rudd, Michael T ; Hollenstein, Kaspar ; Tolstikova, Alexandra ; White, Thomas A ; Hunter, Mark S ; Weierstall, Uwe ; Liu, Wei ; Babaoglu, Kerim ; Moore, Eric L ; Katz, Ryan D ; Shipman, Jennifer M ; Garcia-Calvo, Margarita ; Sharma, Sujata ; Sheth, Payal ; Soisson, Stephen M ; Stevens, Raymond C ; Katritch, Vsevolod ; Cherezov, Vadim Slac National Accelerator Lab. (Slac), Menlo Park, Ca (United States) (Corporate Author)

Nature (London), 20 April 2017, Vol.544(7650) [Peer Reviewed Journal]

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25
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Bacteria establish an aqueous living space in plants crucial for virulence

Xin, Xiu-Fang ; Nomura, Kinya ; Aung, Kyaw ; Velásquez, André C ; Yao, Jian ; Boutrot, Freddy ; Chang, Jeff H ; Zipfel, Cyril ; He, Sheng Yang Michigan State Univ., East Lansing, Mi (United States) (Corporate Author)

Nature (London), 24 November 2016, Vol.539(7630) [Peer Reviewed Journal]

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26
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Whole-genome landscapes of major melanoma subtypes

Hayward, Nicholas K ; Wilmott, James S ; Waddell, Nicola ; Johansson, Peter A ; Field, Matthew A ; Nones, Katia ; Patch, Ann-Marie ; Kakavand, Hojabr ; Alexandrov, Ludmil B ; Burke, Hazel ; Jakrot, Valerie ; Kazakoff, Stephen ; Holmes, Oliver ; Leonard, Conrad ; Sabarinathan, Radhakrishnan ; Mularoni, Loris ; Wood, Scott ; Xu, Qinying ; Waddell, Nick ; Tembe, Varsha ; Pupo, Gulietta M ; De Paoli-Iseppi, Ricardo ; Vilain, Ricardo E ; Shang, Ping ; Lau, Loretta M. S ; Dagg, Rebecca A ; Schramm, Sarah-Jane ; Pritchard, Antonia ; Dutton-Regester, Ken ; Newell, Felicity ; Fitzgerald, Anna ; Shang, Catherine A ; Grimmond, Sean M ; Pickett, Hilda A ; Yang, Jean Y ; Stretch, Jonathan R ; Behren, Andreas ; Kefford, Richard F ; Hersey, Peter ; Long, Georgina V ; Cebon, Jonathan ; Shackleton, Mark ; Spillane, Andrew J ; Saw, Robyn P. M ; López-Bigas, Núria ; Pearson, John V ; Thompson, John F ; Scolyer, Richard A ; Mann, Graham J Los Alamos National Lab. (Lanl), Los Alamos, Nm (United States) (Corporate Author)

Nature (London), 03 May 2017, Vol.545(7653) [Peer Reviewed Journal]

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27
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Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography

Stagno, J. R ; Liu, Y ; Bhandari, Y. R ; Conrad, C. E ; Panja, S ; Swain, M ; Fan, L ; Nelson, G ; Li, C ; Wendel, D. R ; White, T. A ; Coe, J. D ; Wiedorn, M. O ; Knoska, J ; Oberthuer, D ; Tuckey, R. A ; Yu, P ; Dyba, M ; Tarasov, S. G ; Weierstall, U ; Grant, T. D ; Schwieters, C. D ; Zhang, J ; Ferré-D’amaré, A. R ; Fromme, P ; Draper, D. E ; Liang, M ; Hunter, M. S ; Boutet, S ; Tan, K ; Zuo, X ; Ji, X ; Barty, A ; Zatsepin, N. A ; Chapman, H. N ; Spence, J. C. H ; Woodson, S. A ; Wang, Y. -X Slac National Accelerator Lab., Menlo Park, Ca (United States) (Corporate Author) ; Argonne National Lab. (Anl), Argonne, Il (United States) (Corporate Author)

Nature (London), 14 November 2016, Vol.541(7636) [Peer Reviewed Journal]

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28
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Initial Recognition of a Cellodextrin Chain in the Cellulose-Binding Tunnel May Affect Cellobiohydrolase Directional Specificity

Ghattyvenkatakrishna, Pavan k ; Alekozai, Emal m ; Beckham, Gregg t ; Schulz, Roland ; Crowley, Michael f ; Uberbacher, Edward c ; Cheng, Xiaolin Oak Ridge National Lab. (Ornl), Oak Ridge, Tn (United States). Bioenergy Science Center (Besc) (Corporate Author)

Biophysical Journal, 19 February 2013, Vol.104(4) [Peer Reviewed Journal]

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29
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Modification of Salmonella Lipopolysaccharides Prevents the Outer Membrane Penetration of Novobiocin

Nobre, Thatyane m ; Martynowycz, Michael w ; Andreev, Konstantin ; Kuzmenko, Ivan ; Nikaido, Hiroshi ; Gidalevitz, David Argonne National Lab. (Anl), Argonne, Il (United States) (Corporate Author)

Biophysical Journal, 01 December 2015, Vol.109(12) [Peer Reviewed Journal]

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30
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A functional selectivity mechanism at the serotonin-2A GPCR involves ligand-dependent conformations of intracellular loop 2

Perez-Aguilar, Jose Manuel ; Shan, Jufang ; Levine, Michael V ; Khelashvili, George ; Weinstein, Harel Cornell Univ., Ithaca, Ny (United States). Weill Medical College (Corporate Author)

Journal of the American Chemical Society, 14 October 2014, Vol.136(45) [Peer Reviewed Journal]

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31
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Productivity Is a Poor Predictor of Plant Species Richness

Peter B. Adler ; et Al Usda Forest Service-Savannah River, New Ellenton, SC (Corporate Author)

Science (Washington, D.C.), 22 September 2011, Vol.333(1) [Peer Reviewed Journal]

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32
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Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

J Song ; O Rechkoblit ; T Bestor ; D Patel Brookhaven National Laboratory (Bnl) (Corporate Author)

Science (Washington, D.C.), 31 December 2011, Vol.331(6020) [Peer Reviewed Journal]

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33
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Structural transitions in conserved, ordered Beclin 1 domains essential to regulating autophagy

Glover, Karen ; Li, Yue ; Mukhopadhyay, Shreya ; Leuthner, Zoe ; Chakravarthy, Srinivas ; Colbert, Christopher L ; Sinha, Sangita C Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Journal of Biological Chemistry, 10 August 2017, Vol.292(39) [Peer Reviewed Journal]

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34
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Structural and Mechanistic Insights into Hemoglobin-catalyzed Hydrogen Sulfide Oxidation and the Fate of Polysulfide Products

Vitvitsky, Victor ; Yadav, Pramod K ; An, Sojin ; Seravalli, Javier ; Cho, Uhn-Soo ; Banerjee, Ruma Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Journal of Biological Chemistry, 17 February 2017, Vol.292(13) [Peer Reviewed Journal]

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35
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A mosquito hemolymph odorant-binding protein family member specifically binds juvenile hormone

Kim, Il Hwan ; Pham, Van ; Jablonka, Willy ; Goodman, Walter G ; Ribeiro, José M. C ; Andersen, John F Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Journal of Biological Chemistry, 27 July 2017, Vol.292(37) [Peer Reviewed Journal]

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36
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Subunit Arrangement and Phenylethanolamine Binding in GluN1/GluN2B NMDA Receptors

E Karakas ; N Simorowski ; H Furukawa Brookhaven National Laboratory (Bnl) (Corporate Author)

Nature, 31 December 2011, Vol.475(7355) [Peer Reviewed Journal]

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37