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19 Results  for Everything (Includes Articles)

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1
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Chemoselective Peptide Modification via Photocatalytic Tryptophan β-Position Conjugation

Yu, Younong ; Zhang, Li-Kang ; Buevich, Alexei V ; Li, Guoqing ; Tang, Haiqun ; Vachal, Petr ; Colletti, Steven L ; Shi, Zhi-Cai

Journal of the American Chemical Society, 06 June 2018, Vol.140(22), pp.6797-6800 [Peer Reviewed Journal]

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2
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A new synthesis of 3,4-disubstituted 1,2,5-thiadiazoles

Biju, Purakkattle ; Yu, Younong

Tetrahedron Letters, 2007, Vol.48(30), pp.5279-5282 [Peer Reviewed Journal]

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3
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Synthesis of the oxygenated pactamycin core

Knapp, Spencer ; Yu, Younong

Organic letters, 29 March 2007, Vol.9(7), pp.1359-62 [Peer Reviewed Journal]

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4
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Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like properties

Xiao, Dong ; Zhu, Xiaohong ; Yu, Younong ; Shao, Ning ; Wu, Jie ; Mccormick, Kevin D ; Dhondi, Pawan ; Qin, Jun ; Mazzola, Robert ; Tang, Haiqun ; Rao, Ashwin ; Siliphaivanh, Phieng ; Qiu, Hongchen ; Yang, Xiaoxin ; Rivelli, Maria ; Garlisi, Charles G ; Eckel, Steve ; Mukhopadhyay, Gitali ; Correll, Craig ; Rindgen, Diane

Bioorganic & Medicinal Chemistry Letters, 15 March 2014, Vol.24(6), pp.1615-1620 [Peer Reviewed Journal]

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5
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Discovery of novel BTK inhibitors with carboxylic acids

Gao, Xiaolei ; Wang, James ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto ; Boga, Sobhana Babu ; Alhassan, Abdul-Basit ; Selyutin, Oleg ; Yu, Wensheng ; Yu, Younong ; Anand, Rajan ; Liu, Shilan ; Yang, Chundao ; Wu, Hao ; Cai, Jiaqiang ; Cooper, Alan ; Zhu, Hugh ; Maloney, Kevin ; Gao, Ying-Duo ; Fischmann, Thierry O

Bioorganic & Medicinal Chemistry Letters, 15 March 2017, Vol.27(6), pp.1471-1477 [Peer Reviewed Journal]

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Discovery of 3-morpholino-imidazole[1,5-a]pyrazine BTK inhibitors for rheumatoid arthritis

Boga, Sobhana Babu ; Alhassan, Abdul-Basit ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto ; Gao, Xiaolei ; Wang, James ; Yu, Younong ; Anand, Rajan ; Liu, Shilan ; Yang, Chundao ; Wu, Hao ; Cai, Jiaqiang ; Zhu, Hugh ; Desai, Jagdish ; Maloney, Kevin ; Gao, Ying-Duo ; Fischmann, Thierry O ; Presland, Jeremy ; Mansueto, My

Bioorganic & Medicinal Chemistry Letters, 15 August 2017, Vol.27(16), pp.3939-3943 [Peer Reviewed Journal]

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7
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Use of molecular modeling aided design to dial out hERG liability in adenosine A2A receptor antagonists

Deng, Qiaolin ; Lim, Yeon-Hee ; Anand, Rajan ; Yu, Younong ; Kim, Jae-Hun ; Zhou, Wei ; Zheng, Junying ; Tempest, Paul ; Levorse, Dorothy ; Zhang, Xiaoping ; Greene, Scott ; Mullins, Deborra ; Culberson, Chris ; Sherborne, Brad ; Parker, Eric M ; Stamford, Andrew ; Ali, Amjad

Bioorganic & Medicinal Chemistry Letters, 01 August 2015, Vol.25(15), pp.2958-2962 [Peer Reviewed Journal]

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8
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Substituted dibenzoc,hcinnolines: topoisomerase I-targeting anticancer agents

Yu, Younong ; Singh, Sudhir K ; Liu, Angela ; Li, Tsai-Kun ; Liu, Leroy F ; Lavoie, Edmond J

Bioorganic & medicinal chemistry, 03 April 2003, Vol.11(7), pp.1475-91 [Peer Reviewed Journal]

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Discovery of 8-Amino-imidazo[1,5- a ]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis

Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto ; Gao, Xiaolei ; Wang, James ; Boga, Sobhana Babu ; Alhassan, Abdul-Basit ; Yu, Younong ; Vaccaro, Henry ; Liu, Shilan ; Yang, Chundao ; Wu, Hao ; Cooper, Alan ; de Man, Jos ; Kaptein, Allard ; Maloney, Kevin ; Hornak, Viktor ; Gao, Ying-Duo ; Fischmann, Thierry O ; Raaijmakers, Hans ; Vu-Pham, Diep ; Presland, Jeremy ; Mansueto, My ; Xu, Zangwei ; Leccese, Erica ; Zhang-Hoover, Jie ; Knemeyer, Ian ; Garlisi, Charles G ; Bays, Nathan ; Stivers, Peter ; Brandish, Philip E ; Hicks, Alexandra ; Kim, Ronald ; Kozlowski, Joseph A Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

ACS Medicinal Chemistry Letters, 11 February 2016, Vol.7(2) [Peer Reviewed Journal]

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10
Identification of Oxidation Products of (−)-Epigallocatechin Gallate and (−)-Epigallocatechin with H 2 O 2
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Identification of Oxidation Products of (−)-Epigallocatechin Gallate and (−)-Epigallocatechin with H 2 O 2

Zhu, Nanqun ; Huang, Tzou-Chi ; Yu, Younong ; Lavoie, Edmond J. ; Yang, Chung S. ; Ho, Chi-Tang

Journal of Agricultural and Food Chemistry, 04/2000, Vol.48(4), pp.979-981 [Peer Reviewed Journal]

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11
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Discovery of 2-hydroxy-N,N-dimethyl-3-{2-(R)-1-(5- methylfuran-2-yl)propylamino-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): a potent, orally bioavailable CXCR2/CXCR1 receptor antagonist

Dwyer, Michael P ; Yu, Younong ; Chao, Jianping ; Aki, Cynthia ; Chao, Jianhua ; Biju, Purakkattle ; Girijavallabhan, Viyyoor ; Rindgen, Diane ; Bond, Richard ; Mayer-Ezel, Rosemary ; Jakway, James ; Hipkin, R William ; Fossetta, James ; Gonsiorek, Waldemar ; Bian, Hong ; Fan, Xuedong ; Terminelli, Carol ; Fine, Jay ; Lundell, Daniel ; Merritt

Journal of medicinal chemistry, 28 December 2006, Vol.49(26), pp.7603-6 [Peer Reviewed Journal]

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12
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Fluoroalkyl α side chain containing 3,4-diamino-cyclobutenediones as potent and orally bioavailable CXCR2–CXCR1 dual antagonists

Biju, Purakkattle ; Taveras, Arthur G ; Dwyer, Michael P ; Yu, Younong ; Chao, Jianhua ; Hipkin, R. William ; Fan, Xuedong ; Rindgen, Diane ; Fine, Jay ; Lundell, Daniel

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(5), pp.1431-1433 [Peer Reviewed Journal]

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13
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3,4-Diamino-1,2,5-thiadiazole as potent and selective CXCR2 antagonists

Biju, Purakkattle ; Taveras, Arthur G ; Yu, Younong ; Zheng, Junying ; Hipkin, R. William ; Fossetta, James ; Fan, Xuedong ; Fine, Jay ; Lundell, Daniel

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(5), pp.1434-1437 [Peer Reviewed Journal]

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14
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Research Dataset
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CCDC 621055: Experimental Crystal Structure Determination

Knapp, S. ; Yu, Younong

2007

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15
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Diaminocyclobutenediones as potent and orally bioavailable CXCR2 receptor antagonists: SAR in the phenolic amide region

Aki, Cynthia ; Chao, Jianping ; Ferreira, Johan A ; Dwyer, Michael P ; Yu, Younong ; Chao, Jianhua ; Merritt, Robert J ; Lai, Gaifa ; Wu, Minglang ; Hipkin, R. William ; Fan, Xuedong ; Gonsiorek, Waldemar ; Fosseta, James ; Rindgen, Diane ; Fine, Jay ; Lundell, Daniel ; Taveras, Arthur G ; Biju, Purakkattle

Bioorganic & Medicinal Chemistry Letters, 01 August 2009, Vol.19(15), pp.4446-4449 [Peer Reviewed Journal]

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16
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3,4-Diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists

Biju, Purakkattle ; Taveras, Arthur ; Yu, Younong ; Zheng, Junying ; Chao, Jianhua ; Rindgen, Diane ; Jakway, James ; Hipkin, R. William ; Fossetta, James ; Fan, Xuedong ; Fine, Jay ; Qiu, Hongchen ; Merritt, J. Robert ; Baldwin, John J

Bioorganic & Medicinal Chemistry Letters, 2008, Vol.18(1), pp.228-231 [Peer Reviewed Journal]

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17
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C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists

Chao, Jianhua ; Taveras, Arthur G ; Chao, Jianping ; Aki, Cynthia ; Dwyer, Michael ; Yu, Younong ; Purakkattle, Biju ; Rindgen, Diane ; Jakway, James ; Hipkin, William ; Fosetta, James ; Fan, Xuedong ; Lundell, Daniel ; Fine, Jay ; Minnicozzi, Michael ; Phillips, Jonathan ; Merritt, J. Robert

Bioorganic & Medicinal Chemistry Letters, 2007, Vol.17(13), pp.3778-3783 [Peer Reviewed Journal]

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18
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Synthesis and structure–activity relationships of heteroaryl substituted-3,4-diamino-3-cyclobut-3-ene-1,2-dione CXCR2/CXCR1 receptor antagonists

Yu, Younong ; Dwyer, Michael P ; Chao, Jianping ; Aki, Cynthia ; Chao, Jianhua ; Purakkattle, Biju ; Rindgen, Diane ; Bond, Richard ; Mayer-Ezel, Rosemary ; Jakway, James ; Qiu, Hongchen ; Hipkin, R. William ; Fossetta, James ; Gonsiorek, Waldemar ; Bian, Hong ; Fan, Xuedong ; Terminelli, Carol ; Fine, Jay ; Lundell, Daniel ; Merritt, J. Robert

Bioorganic & Medicinal Chemistry Letters, 2008, Vol.18(4), pp.1318-1322 [Peer Reviewed Journal]

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19
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Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Yu, Wensheng ; Liu, Jian ; Yu, Younong ; Zhang, Vivian ; Clausen, Dane ; Kelly, Joseph ; Wolkenberg, Scott ; Beshore, Douglas ; Duffy, Joseph L ; Chung, Christine C ; Myers, Robert W ; Klein, Daniel J ; Fells, James ; Holloway, Kate ; Wu, Jin ; Wu, Guoxin ; Howell, Bonnie J ; Barnard, Richard J.O ; Kozlowski, Joseph

Bioorganic & Medicinal Chemistry Letters, 01 July 2020, Vol.30(13) [Peer Reviewed Journal]

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