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Biological Evaluation of a Mitochondrial Phosphoenolpyruvate Carboxykinase Inhibitor

Sergio Rodríguez-Arévalo ; Sònia Abás ; Marc Aragó ; Juan Moreno-Felici ; Petra Hyroššová ; Jose Carlos Perales ; Carles Galdeano ; Tiziana Ginex ; Francisco Javier Luque ; Carmen Escolano

Proceedings, 01 September 2019, Vol.22(1), p.95 [Peer Reviewed Journal]

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Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the differentiation of embryonic stem cells towards pancreatic lineage and pancreatic beta cell function

Kubi, John A ; Chen, Andy C H ; Fong, Sze Wan ; Lai, Keng Po ; Wong, Chris K C ; Yeung, William S B ; Lee, Kai Fai ; Lee, Yin Lau

Environment international, 10 June 2019, Vol.130, pp.104885 [Peer Reviewed Journal]

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A role for foregut tyrosine metabolism in glucose tolerance

Korner, Judith ; Cline, Gary W ; Slifstein, Mark ; Barba, Pasquale ; Rayat, Gina R ; Febres, Gerardo ; Leibel, Rudolph L ; Maffei, Antonella ; Harris, Paul E

Molecular metabolism, May 2019, Vol.23, pp.37-50 [Peer Reviewed Journal]

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cAMP-PKA dependent ERK1/2 activation is necessary for vanillic acid potentiated glucose-stimulated insulin secretion in pancreatic β-cells

Mahendra, V.P ; Haware, Devendra J ; Kumar, Ravi

Journal of Functional Foods, May 2019, Vol.56, pp.110-118 [Peer Reviewed Journal]

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Computational modeling and analysis of the impacts of sleep deprivation on glucose stimulated insulin secretion

Ashraf, Hufsah ; Ahmad, Jamil ; Hassan, Azka ; Ali, Amjad

Bio Systems, 18 February 2019, Vol.179, pp.1-14 [Peer Reviewed Journal]

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Vitamin D Increases Glucose Stimulated Insulin Secretion from Insulin Producing Beta Cells (INS1E)

Bornstedt, Mette Eskild ; Gjerlaugsen, Nina ; Pepaj, Milaim ; Bredahl, May K L ; Thorsby, Per M

International Journal of Endocrinology and Metabolism, 2019, Vol.17(1)

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The renin-angiotensin system as a target to solve the riddle of endocrine pancreas homeostasis

Graus-Nunes, Francielle ; Souza-Mello, Vanessa

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, January 2019, Vol.109, pp.639-645 [Peer Reviewed Journal]

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Comparison of approximate assessments of the harmfulness of mining shocks using ground and building foundation vibrations

Krystyna Kuzniar ; Krystyna Stec ; Tadeusz Tatara

Journal of Measurements in Engineering, 01 December 2018, Vol.6(4), pp.218-225 [Peer Reviewed Journal]

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Palmitate-Induced Insulin Hypersecretion and Later Secretory Decline Associated with Changes in Protein Expression Patterns in Human Pancreatic Islets

Groebe, Karlfried ; Cen, Jing ; Schvartz, Domitille ; Sargsyan, Ernest ; Chowdhury, Azazul ; Roomp, Kirsten ; Schneider, Reinhard ; Alderborn, Anders ; Sanchez, Jean-Charles ; Bergsten, Peter

Journal of proteome research, 02 November 2018, Vol.17(11), pp.3824-3836 [Peer Reviewed Journal]

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Innovation and network multiplexity: R&D and the concurrent effects of two collaboration networks in an emerging economy

Andrade Rojas, Mariana Giovanna ; Solis, Edgar Rogelio Ramirez ; Zhu, John Jianjun

Research Policy, July 2018, Vol.47(6), pp.1111-1124 [Peer Reviewed Journal]

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Secretase inhibitors for the treatment of Alzheimer's disease: Long road ahead

Kumar, Devendra ; Ganeshpurkar, Ankit ; Kumar, Dileep ; Modi, Gyan ; Gupta, Sanjeev Kumar ; Singh, Sushil Kumar

European journal of medicinal chemistry, 25 March 2018, Vol.148, pp.436-452 [Peer Reviewed Journal]

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Discovery of a novel potent GPR40 full agonist

Meegalla, Sanath K ; Huang, Hui ; Martin, Tonya ; Xu, June ; Zhao, Shuyuan ; Liu, Jianying ; Hall, Meghan ; Gunnet, Joe ; Wang, Yuanping ; Rady, Brian ; Silva, Jose ; Otieno, Monicah ; Arnoult, Eric ; Paul Lee, S ; Pocai, Alessandro ; Player, Mark R

Bioorganic & medicinal chemistry letters, 15 February 2018, Vol.28(4), pp.720-726 [Peer Reviewed Journal]

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Discovery of novel benzobthiophene tetrazoles as non-carboxylate GPR40 agonists

Huang, Hui ; Winters, Michael P ; Meegalla, Sanath K ; Arnoult, Eric ; Paul Lee, S ; Zhao, Shuyuan ; Martin, Tonya ; Rady, Brian ; Liu, Jianying ; Towers, Meghan ; Otieno, Monicah ; Xu, Fran ; Lim, Heng Keang ; Silva, Jose ; Pocai, Alessandro ; Player, Mark R

Bioorganic & medicinal chemistry letters, 01 February 2018, Vol.28(3), pp.429-436 [Peer Reviewed Journal]

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2-OMe-lysophosphatidylcholine analogues are GPR119 ligands and activate insulin secretion from βTC-3 pancreatic cells: Evaluation of structure-dependent biological activity

Drzazga, Anna ; Sowińska, Agata ; Krzemińska, Agnieszka ; Okruszek, Andrzej ; Paneth, Piotr ; Koziołkiewicz, Maria ; Gendaszewska-Darmach, Edyta

Biochimica et biophysica acta. Molecular and cell biology of lipids, January 2018, Vol.1863(1), pp.91-103 [Peer Reviewed Journal]

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Targeting Notch signalling pathway of cancer stem cells

Venkatesh, Vandana ; Nataraj, Raghu ; Thangaraj, Gopenath S ; Karthikeyan, Murugesan ; Gnanasekaran, Ashok ; Kaginelli, Shanmukhappa B ; Kuppanna, Gobianand ; Kallappa, Chandrashekrappa Gowdru ; Basalingappa, Kanthesh M

Stem cell investigation, 2018, Vol.5, pp.5

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16
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Text Resource
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Identifying New Treatment Options and Risk Factors for Type 2 Diabetes: The Potential Role of Thymoquinone and Persistent Organic Pollutants

Karandrea, Shpetim

2017

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17
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Article
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The dynamic plasticity of insulin production in β-cells

Boland, Brandon B ; Rhodes, Christopher J ; Grimsby, Joseph S

Molecular metabolism, September 2017, Vol.6(9), pp.958-973 [Peer Reviewed Journal]

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18
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Article
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Transcribing β-cell mitochondria in health and disease

Mulder, Hindrik

Molecular metabolism, September 2017, Vol.6(9), pp.1040-1051 [Peer Reviewed Journal]

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19
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Article
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Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice

Seshadri, Nivedita ; Jonasson, Michael E ; Hunt, Kristin L ; Xiang, Bo ; Cooper, Steven ; Wheeler, Michael B ; Dolinsky, Vernon W ; Doucette, Christine A

Molecular metabolism, July 2017, Vol.6(7), pp.760-769 [Peer Reviewed Journal]

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20
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Regulation of pancreatic β-cell function and mass dynamics by prostaglandin signaling

Carboneau, Bethany A ; Breyer, Richard M ; Gannon, Maureen

Journal of cell communication and signaling, June 2017, Vol.11(2), pp.105-116 [Peer Reviewed Journal]

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21
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NNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells

Santos, Laila R B ; Muller, Carole ; De Souza, Arnaldo H ; Takahashi, Hilton K ; Spégel, Peter ; Sweet, Ian R ; Chae, Heeyoung ; Mulder, Hindrik ; Jonas, Jean-Christophe

Molecular metabolism, June 2017, Vol.6(6), pp.535-547 [Peer Reviewed Journal]

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22
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Article
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Geniposide protects pancreatic β cells from high glucose-mediated injury by activation of AMP-activated protein kinase

Liu, Chunyan ; Hao, Yanan ; Yin, Fei ; Zhang, Yonglan ; Liu, Jianhui

Cell biology international, May 2017, Vol.41(5), pp.544-554 [Peer Reviewed Journal]

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23
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Perspectives on geospatial information science education: an example of urban planners in Southern Africa

Walter Musakwa

Geo-spatial Information Science, 01 April 2017, Vol.20(2), pp.201-208 [Peer Reviewed Journal]

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24
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Article
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Astrocyte IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic inflammation

Douglass, J D ; Dorfman, M D ; Fasnacht, R ; Shaffer, L D ; Thaler, J P

Molecular metabolism, April 2017, Vol.6(4), pp.366-373 [Peer Reviewed Journal]

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25
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Synthesis and glucose-stimulate insulin secretion (GSIS) evaluation of vindoline derivatives

Xiao, Chengqian ; Tian, Yunan ; Lei, Min ; Chen, Fanglei ; Gan, Xianwen ; Yao, Xingang ; Shen, Xu ; Chen, Jing ; Hu, Lihong

Bioorganic & medicinal chemistry letters, 01 March 2017, Vol.27(5), pp.1316-1318 [Peer Reviewed Journal]

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26
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Metformin prevents glucotoxicity by alleviating oxidative and ER stress-induced CD36 expression in pancreatic beta cells

Moon, Jun ; Karunakaran, Udayakumar ; Elumalai, Suma ; Lee, In-Kyu ; Lee, Hyoung ; Kim, Yong-Woon ; Won, Kyu

Journal of Diabetes and its Complications, Jan 01, 2017, Vol.31(1), pp.21-30 [Peer Reviewed Journal]

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27
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Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

Guo, Liangqin ; Parker, Dann L ; Zang, Yi ; Sweis, Ramzi F ; Liu, Weiguo ; Sherer, Edward C ; Buist, Nicole ; Terebetski, Jenna ; Kelly, Terri ; Bugianesi, Randal ; Priest, Birgit T ; Dingley, Karen H ; Li, Xiaofang ; Mitelman, Stan ; Salituro, Gino ; Trujillo, Maria E ; Pachanski, Michele ; Kirkland, Melissa ; Powles, Mary Ann ; Eiermann, George J ; Feng, Yue ; Shang, Jin ; Howard, Andrew D ; Ujjainwalla, Feroze ; Sinz, Christopher J ; Debenham, John S ; Edmondson, Scott D ; Nargund, Ravi P ; Hagmann, William K ; Li, Derun

ACS medicinal chemistry letters, 08 December 2016, Vol.7(12), pp.1107-1111 [Peer Reviewed Journal]

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28
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Hypothalamic AMP-Activated Protein Kinase Regulates Biphasic Insulin Secretion from Pancreatic β Cells during Fasting and in Type 2 Diabetes

Kume, Shinji ; Kondo, Motoyuki ; Maeda, Shiro ; Nishio, Yoshihiko ; Yanagimachi, Tsuyoshi ; Fujita, Yukihiro ; Haneda, Masakazu ; Kondo, Keiko ; Sekine, Akihiro ; Araki, Shin-Ich ; Araki, Hisazumi ; Chin-Kanasaki, Masami ; Ugi, Satoshi ; Koya, Daisuke ; Kitahara, Sawako ; Maeda, Kiyosumi ; Kashiwagi, Atsunori ; Uzu, Takashi ; Maegawa, Hiroshi

EBioMedicine, November 2016, Vol.13, pp.168-180 [Peer Reviewed Journal]

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29
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Discovery of novel potent imidazo1,2-bpyridazine PDE10a inhibitors

Meegalla, Sanath K ; Huang, Hui ; Illig, Carl R ; Parks, Daniel J ; Chen, Jinsheng ; Lee, Yu-Kai ; Wilson, Kenneth J ; Patel, Sharmila K ; Cheung, Wing S ; Lu, Tianbao ; Kirchner, Thomas ; Askari, Hossein B ; Geisler, John ; Patch, Raymond J ; Gibbs, Alan C ; Rady, Brian ; Connelly, Margery ; Player, Mark R

Bioorganic & medicinal chemistry letters, 01 September 2016, Vol.26(17), pp.4216-22 [Peer Reviewed Journal]

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30
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An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion

Mccommis, Kyle S ; Hodges, Wesley T ; Bricker, Daniel K ; Wisidagama, Dona R ; Compan, Vincent ; Remedi, Maria S ; Thummel, Carl S ; Finck, Brian N

Molecular metabolism, August 2016, Vol.5(8), pp.602-614 [Peer Reviewed Journal]

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31
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Fasiglifam (TAK‐875) has dual potentiating mechanisms via Gαq‐GPR40/FFAR1 signaling branches on glucose‐dependent insulin secretion

Sakuma, Kensuke ; Yabuki, Chiori ; Maruyama, Minoru ; Abiru, Akiko ; Komatsu, Hidetoshi ; Negoro, Nobuyuki ; Tsujihata, Yoshiyuki ; Takeuchi, Koji ; Habata, Yugo ; Mori, Masaaki

Pharmacology Research & Perspectives, June 2016, Vol.4(3), pp.n/a-n/a [Peer Reviewed Journal]

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32
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A comprehensive lipidomic screen of pancreatic β-cells using mass spectroscopy defines novel features of glucose-stimulated turnover of neutral lipids, sphingolipids and plasmalogens

Pearson, Gemma L ; Mellett, Natalie ; Chu, Kwan Yi ; Boslem, Ebru ; Meikle, Peter J ; Biden, Trevor J

Molecular metabolism, June 2016, Vol.5(6), pp.404-414 [Peer Reviewed Journal]

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33
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Asian Scheme Plans Overseas Manager Hires

Global Money Management, Feb 2, 2016

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34
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Acute intravenous glucose load impairs early insulin secretion and insulin content in islet β cells in mice

Yan, Dien ; Zhao, Yinan ; Gao, Xiuying ; Zhou, Yingsheng

Life sciences, 01 January 2016, Vol.144, pp.148-55 [Peer Reviewed Journal]

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35
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Notch signalling pathway as an oncogenic factor involved in cancer development

Brzozowa-Zasada, Marlena ; Piecuch, Adam ; Dittfeld, Anna ; Mielańczyk, Łukasz ; Michalski, Marek ; Wyrobiec, Grzegorz ; Harabin-Słowińska, Marzena ; Kurek, Józef ; Wojnicz, Romuald

Contemporary Oncology, 2016, Vol.20(4), p.267-272 [Peer Reviewed Journal]

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36
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Glicentin-related pancreatic polypeptide inhibits glucose-stimulated insulin secretion from the isolated pancreas of adult male rats

Whiting, Lynda ; Stewart, Kevin W ; Hay, Deborah L ; Harris, Paul W ; Choong, Yee S ; Phillips, Anthony R J ; Brimble, Margaret A ; Cooper, Garth J S

Physiological reports, December 2015, Vol.3(12) [Peer Reviewed Journal]

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37
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α/β-Hydrolase domain-6 and saturated long chain monoacylglycerol regulate insulin secretion promoted by both fuel and non-fuel stimuli

Zhao, Shangang ; Poursharifi, Pegah ; Mugabo, Yves ; Levens, Emily J ; Vivot, Kevin ; Attane, Camille ; Iglesias, Jose ; Peyot, Marie-Line ; Joly, Erik ; Madiraju, S R Murthy ; Prentki, Marc

Molecular metabolism, December 2015, Vol.4(12), pp.940-50 [Peer Reviewed Journal]

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38
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Specific and redundant roles of PKB[alpha]/AKT1 and PKB[beta]/AKT2 in human pancreatic islets

Dietrich, Maren G. ; Zuellig, Richard A. ; Spinas, Giatgen A. ; Lehmann, Roger ; Tschopp, Oliver ; Niessen, Markus

Experimental Cell Research, Oct 15, 2015, pp.82-88 [Peer Reviewed Journal]

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39