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PDIA6 regulates insulin secretion by selectively inhibiting the RIDD activity of IRE1

Eletto, Daniela ; Eletto, Davide ; Boyle, Sarah ; Argon, Yair

FASEB Journal, February 2016, Vol.30(2), pp.653-665 [Peer Reviewed Journal]

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Acute intravenous glucose load impairs early insulin secretion and insulin content in islet β cells in mice

Yan, Dien ; Zhao, Yinan ; Gao, Xiuying ; Zhou, Yingsheng

Life Sciences, 01 January 2016, Vol.144, pp.148-155 [Peer Reviewed Journal]

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Differential regulation of mouse pancreatic islet insulin secretion and Smad proteins by activin ligands

Wu, Haiya ; Mezghenna, Karima ; Marmol, Patricia ; Guo, Tingqing ; Moliner, Annalena ; Yang, Shao-Nian ; Berggren, Per-Olof ; Ibáñez, Carlos

Diabetologia, 2014, Vol.57(1), pp.148-156 [Peer Reviewed Journal]

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Site location analysis for small hydropower using geo-spatial information system

Yi, Choong-Sung ; Lee, Jin-Hee ; Shim, Myung-Pil

Renewable Energy, April 2010, Vol.35(4), pp.852-861 [Peer Reviewed Journal]

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Deficiency in RNA editing enzyme ADAR2 impairs regulated exocytosis

Yang, Liu ; Zhao, Liyun ; Gan, Zhenji ; He, Zixuan ; Xu, Jingyue ; Gao, Xiang ; Wang, Xiaorui ; Han, Weiping ; Chen, Liangyi ; Xu, Tao ; Li, Wenjun ; Liu, Yong

FASEB Journal, October 2010, Vol.24(10), pp.3720-3732 [Peer Reviewed Journal]

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The γ-secretase blocker DAPT impairs recovery from lipopolysaccharide-induced inflammation in rat brain

Nasoohi, S ; Hemmati, A.A ; Moradi, F ; Ahmadiani, A

Neuroscience, 17 May 2012, Vol.210, pp.99-109 [Peer Reviewed Journal]

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Notch signalling pathway as an oncogenic factor involved in cancer development

Brzozowa-Zasada, Marlena ; Piecuch, Adam ; Dittfeld, Anna ; Mielańczyk, Łukasz ; Michalski, Marek ; Wyrobiec, Grzegorz ; Harabin-Słowińska, Marzena ; Kurek, Józef ; Wojnicz, Romuald

Contemporary Oncology, 2016, Vol.20(4), p.267-272 [Peer Reviewed Journal]

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Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2)

Barlow, A. ; Xie, J. ; Moore, C. ; Campbell, S. ; Shaw, J. ; Nicholson, M. ; Herbert, T.

Diabetologia, 2012, Vol.55(5), pp.1355-1365 [Peer Reviewed Journal]

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PANDER KO mice on high‐fat diet are glucose intolerant yet resistant to fasting hyperglycemia and hyperinsulinemia

Robert - Cooperman, Claudia E. ; Wilson, Camella G. ; Burkhardt, Brant R.

FEBS Letters, 06 May 2011, Vol.585(9), pp.1345-1349 [Peer Reviewed Journal]

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Discovery of 3-(4-methanesulfonylphenoxy)-N-[1-(2-methoxy-ethoxymethyl)-1H-pyrazol-3-yl]-5-(3-methylpyridin-2-yl)-benzamide as a novel glucokinase activator (GKA) for the treatment of type 2 diabetes mellitus

Park, Kaapjoo ; Lee, Byoung Moon ; Hyun, Kwan Hoon ; Lee, Dong Hoon ; Choi, Hyun Ho ; Kim, Hyunmi ; Chong, Wonee ; Kim, Kyeong Bae ; Nam, Su Youn

Bioorganic & Medicinal Chemistry, 01 April 2014, Vol.22(7), pp.2280-2293 [Peer Reviewed Journal]

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Regulation of pancreatic β-cell function and mass dynamics by prostaglandin signaling

Carboneau, Bethany A ; Breyer, Richard M ; Gannon, Maureen

Journal of cell communication and signaling, June 2017, Vol.11(2), pp.105-116 [Peer Reviewed Journal]

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Potentiation of insulin secretion and improvement of glucose intolerance by combining a novel G protein-coupled receptor 40 agonist DS-1558 with glucagon-like peptide-1 receptor agonists

Nakashima, Ryutaro ; Yano, Tatsuya ; Ogawa, Junko ; Tanaka, Naomi ; Toda, Narihiro ; Yoshida, Masao ; Takano, Rieko ; Inoue, Masahiro ; Honda, Takeshi ; Kume, Shoen ; Matsumoto, Koji

European Journal of Pharmacology, 15 August 2014, Vol.737, pp.194-201 [Peer Reviewed Journal]

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Anchored phosphatases modulate glucose homeostasis

Hinke, Simon A ; Navedo, Manuel F ; Ulman, Allison ; Whiting, Jennifer L ; Nygren, Patrick J ; Tian, Geng ; Jimenez‐Caliani, Antonio J ; Langeberg, Lorene K ; Cirulli, Vincenzo ; Tengholm, Anders ; Dell' Acqua, Mark L ; Santana, L Fernando ; Scott, John D

EMBO Journal, 17 October 2012, Vol.31(20), pp.3991-4004 [Peer Reviewed Journal]

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Anchored phosphatases modulate glucose homeostasis

Hinke, Simon A ; Navedo, Manuel F ; Ulman, Allison ; Whiting, Jennifer L ; Nygren, Patrick J ; Tian, Geng ; Jiménez Caliani, Antonio Javier ; Langeberg, Lorene K. ; Cirulli, Vincenzo ; Tengholm, Anders ; Dell'Acqua, Mark L ; Santana, L Fernando ; Scott, John D.

EMBO journal: European Molecular Biology Organization, 2012, Issue 20, pp.3991-4004 [Peer Reviewed Journal]

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Ghrelin inhibits insulin secretion through the AMPK–UCP2 pathway in β cells

Wang, Ying ; Nishi, Masahiro ; Doi, Asako ; Shono, Takeshi ; Furukawa, Yasushi ; Shimada, Takeshi ; Furuta, Hiroto ; Sasaki, Hideyuki ; Nanjo, Kishio

FEBS Letters, 16 April 2010, Vol.584(8), pp.1503-1508 [Peer Reviewed Journal]

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16
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The nuclear receptor FXR is expressed in pancreatic β‐cells and protects human islets from lipotoxicity

Popescu, Iuliana Ristea ; Helleboid - Chapman, Audrey ; Lucas, Anthony ; Vandewalle, Brigitte ; Dumont, Julie ; Bouchaert, Emmanuel ; Derudas, Bruno ; Kerr - Conte, Julie ; Caron, Sandrine ; Pattou, François ; Staels, Bart

FEBS Letters, 02 July 2010, Vol.584(13), pp.2845-2851 [Peer Reviewed Journal]

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17
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Innovation and network multiplexity: R&D and the concurrent effects of two collaboration networks in an emerging economy

Andrade Rojas, Mariana Giovanna ; Solis, Edgar Rogelio Ramirez ; Zhu, John Jianjun

Research Policy, July 2018, Vol.47(6), pp.1111-1124 [Peer Reviewed Journal]

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18
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Glicentin‐related pancreatic polypeptide inhibits glucose‐stimulated insulin secretion from the isolated pancreas of adult male rats

Whiting, Lynda ; Stewart, Kevin W. ; Hay, Deborah L. ; Harris, Paul W. ; Choong, Yee S. ; Phillips, Anthony R. J. ; Brimble, Margaret A. ; Cooper, Garth J. S.

Physiological Reports, December 2015, Vol.3(12), pp.n/a-n/a [Peer Reviewed Journal]

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19
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Block of K v 1.7 potassium currents increases glucose‐stimulated insulin secretion

Finol‐Urdaneta, Rocio K. ; Remedi, Maria S. ; Raasch, Walter ; Becker, Stefan ; Clark, Robert B. ; Strüver, Nina ; Pavlov, Evgeny ; Nichols, Colin G. ; French, Robert J. ; Terlau, Heinrich

EMBO Molecular Medicine, May 2012, Vol.4(5), pp.424-434 [Peer Reviewed Journal]

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20
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Neuroendocrine regulatory peptide-2 stimulates glucose-induced insulin secretion in vivo and in vitro

Moin, Abu Saleh Md ; Yamaguchi, Hideki ; Rhee, Marie ; Kim, Ji-Wom ; Toshinai, Koji ; Waise, T.M. Zaved ; Naznin, Farhana ; Matsuo, Takashi ; Sasaki, Kazuki ; Minamino, Naoto ; Yoon, Kun-Ho ; Nakazato, Masamitsu

Biochemical and Biophysical Research Communications, 30 November 2012, Vol.428(4), pp.512-517 [Peer Reviewed Journal]

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21
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Autophagy protects against cholesterol-induced apoptosis in pancreatic β-cells

Wu, Jiahua ; Kong, Feijuan ; Pan, Qianqian ; Du, Ying ; Ye, Jun ; Zheng, Fenping ; Li, Hong ; Zhou, Jiaqiang

Biochemical and Biophysical Research Communications, 22 January 2017, Vol.482(4), pp.678-685 [Peer Reviewed Journal]

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22
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Metformin prevents glucotoxicity by alleviating oxidative and ER stress–induced CD36 expression in pancreatic beta cells

Moon, Jun Sung ; Karunakaran, Udayakumar ; Elumalai, Suma ; Lee, In-Kyu ; Lee, Hyoung Woo ; Kim, Yong-Woon ; Won, Kyu Chang

Journal of Diabetes and Its Complications, January 2017, Vol.31(1), pp.21-30 [Peer Reviewed Journal]

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23
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Discovery of novel benzo[b]thiophene tetrazoles as non-carboxylate GPR40 agonists

Huang, Hui ; Winters, Michael P ; Meegalla, Sanath K ; Arnoult, Eric ; Paul Lee, S ; Zhao, Shuyuan ; Martin, Tonya ; Rady, Brian ; Liu, Jianying ; Towers, Meghan ; Otieno, Monicah ; Xu, Fran ; Lim, Heng Keang ; Silva, Jose ; Pocai, Alessandro ; Player, Mark R

Bioorganic & Medicinal Chemistry Letters, 01 February 2018, Vol.28(3), pp.429-436 [Peer Reviewed Journal]

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24
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Hypothalamic AMP-Activated Protein Kinase Regulates Biphasic Insulin Secretion from Pancreatic β Cells during Fasting and in Type 2 Diabetes

Kume, Shinji ; Kondo, Motoyuki ; Maeda, Shiro ; Nishio, Yoshihiko ; Yanagimachi, Tsuyoshi ; Fujita, Yukihiro ; Haneda, Masakazu ; Kondo, Keiko ; Sekine, Akihiro ; Araki, Shin-Ich ; Araki, Hisazumi ; Chin-Kanasaki, Masami ; Ugi, Satoshi ; Koya, Daisuke ; Kitahara, Sawako ; Maeda, Kiyosumi ; Kashiwagi, Atsunori ; Uzu, Takashi ; Maegawa, Hiroshi

EBioMedicine, November 2016, Vol.13, pp.168-180 [Peer Reviewed Journal]

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25
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Role of osteopontin and its regulation in pancreatic islet

Cai, Mengyin ; Bompada, Pradeep ; Salehi, Albert ; Acosta, Juan R ; Prasad, Rashmi B ; Atac, David ; Laakso, Markku ; Groop, Leif ; De Marinis, Yang

Biochemical and Biophysical Research Communications, 01 January 2018, Vol.495(1), pp.1426-1431 [Peer Reviewed Journal]

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26
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The expression of dominant negative TCF7L2 in pancreatic beta cells during the embryonic stage causes impaired glucose homeostasis

Shao, Weijuan ; Xiong, Xiaoquan ; Ip, Wilfred ; Xu, Fenghao ; Song, Zhuolun ; Zeng, Kejing ; Hernandez, Marcela ; Liang, Tao ; Weng, Jianping ; Gaisano, Herbert ; Nostro, M. Cristina ; Jin, Tianru

Molecular Metabolism, April 2015, Vol.4(4), pp.344-352 [Peer Reviewed Journal]

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27
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Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 Agonist

Negoro, Nobuyuki ; Sasaki, Shinobu ; Mikami, Satoshi ; Ito, Masahiro ; Suzuki, Masami ; Tsujihata, Yoshiyuki ; Ito, Ryo ; Harada, Ayako ; Takeuchi, Koji ; Suzuki, Nobuhiro ; Miyazaki, Junichi ; Santou, Takashi ; Odani, Tomoyuki ; Kanzaki, Naoyuki ; Funami, Miyuki ; Tanaka, Toshimasa ; Kogame, Akifumi ; Matsunaga, Shinichiro ; Yasuma, Tsuneo ; Momose

ACS medicinal chemistry letters, 09 September 2010, Vol.1(6), pp.290-4 [Peer Reviewed Journal]

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28
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Reactive oxygen species and uncoupling protein 2 in pancreatic β‐cell function

Pi, J. ; Collins, S.

Diabetes, Obesity and Metabolism, October 2010, Vol.12, pp.141-148 [Peer Reviewed Journal]

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29
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Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction

Kowluru, Anjaneyulu

Biochemical Pharmacology, 15 May 2017, Vol.132, pp.9-17 [Peer Reviewed Journal]

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30
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Fasiglifam (TAK‐875) has dual potentiating mechanisms via Gαq‐GPR40/FFAR1 signaling branches on glucose‐dependent insulin secretion

Sakuma, Kensuke ; Yabuki, Chiori ; Maruyama, Minoru ; Abiru, Akiko ; Komatsu, Hidetoshi ; Negoro, Nobuyuki ; Tsujihata, Yoshiyuki ; Takeuchi, Koji ; Habata, Yugo ; Mori, Masaaki

Pharmacology Research & Perspectives, June 2016, Vol.4(3), pp.n/a-n/a [Peer Reviewed Journal]

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31
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CNTF protects MIN6 cells against apoptosis induced by Alloxan and IL-1β through downregulation of the AMPK pathway

Santos, Gustavo J ; Oliveira, Camila A.M ; Boschero, Antonio C ; Rezende, Luiz F

Cellular Signalling, 2011, Vol.23(10), pp.1669-1676 [Peer Reviewed Journal]

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32
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An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion

Mccommis, Kyle S ; Hodges, Wesley T ; Bricker, Daniel K ; Wisidagama, Dona R ; Compan, Vincent ; Remedi, Maria S ; Thummel, Carl S ; Finck, Brian N

Molecular Metabolism, August 2016, Vol.5(8), pp.602-614 [Peer Reviewed Journal]

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33
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Calcium/calmodulin-dependent serine protein kinase is involved in exendin-4-induced insulin secretion in INS-1 cells

Zhu, Zheng-Qiu ; Wang, Dong ; Xiang, Dan ; Yuan, Yue-Xing ; Wang, Yao

Metabolism, January 2014, Vol.63(1), pp.120-126 [Peer Reviewed Journal]

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34
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Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity

Wu, Lindsay E ; Samocha-Bonet, Dorit ; Whitworth, P. Tess ; Fazakerley, Daniel J ; Turner, Nigel ; Biden, Trevor J ; James, David E ; Cantley, James

Molecular Metabolism, July 2014, Vol.3(4), pp.465-473 [Peer Reviewed Journal]

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