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1
Effects of pH and Low Density Lipoprotein (LDL) on PCSK9-dependent LDL Receptor Regulation
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Effects of pH and Low Density Lipoprotein (LDL) on PCSK9-dependent LDL Receptor Regulation

Timothy S. Fisher ; Paola Lo Surdo ; Shilpa Pandit ; Marco Mattu ; Joseph C. Santoro ; Doug Wisniewski ; Richard T. Cummings ; Alessandra Calzetta ; Rose M. Cubbon ; Paul A. Fischer ; Anil Tarachandani ; Raffaele De Francesco ; Samuel D. Wright ; Carl P. Sparrow ; Andrea Carfi ; Ayesha Sitlani

Journal of Biological Chemistry, 2007-07-13, Vol.282 (28), p.20502-20512 [Peer Reviewed Journal]

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2
27-Hydroxycholesterol Is an Endogenous Ligand for Liver X Receptor in Cholesterol-loaded Cells
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27-Hydroxycholesterol Is an Endogenous Ligand for Liver X Receptor in Cholesterol-loaded Cells

Fu, Xuan ; Menke, John G ; Chen, Yuli ; Zhou, Gaochao ; MacNaul, Karen L ; Wright, Samuel D ; Sparrow, Carl P ; Lund, Erik G

The Journal of biological chemistry, 2001-10-19, Vol.276 (42), p.38378-38387 [Peer Reviewed Journal]

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3
Structural and Biochemical Characterization of the Wild Type PCSK9-EGF(AB) Complex and Natural Familial Hypercholesterolemia Mutants
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Structural and Biochemical Characterization of the Wild Type PCSK9-EGF(AB) Complex and Natural Familial Hypercholesterolemia Mutants

Matthew J. Bottomley ; Agostino Cirillo ; Laura Orsatti ; Lionello Ruggeri ; Timothy S. Fisher ; Joseph C. Santoro ; Richard T. Cummings ; Rose M. Cubbon ; Paola Lo Surdo ; Alessandra Calzetta ; Alessia Noto ; Jennifer Baysarowich ; Marco Mattu ; Fabio Talamo ; Raffaele De Francesco ; Carl P. Sparrow ; Ayesha Sitlani ; Andrea CarfÃ

Journal of Biological Chemistry, 2009-01-09, Vol.284 (2), p.1313-1323 [Peer Reviewed Journal]

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4
A Potent Synthetic LXR Agonist Is More Effective than Cholesterol Loading at Inducing ABCA1 mRNA and Stimulating Cholesterol Efflux
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A Potent Synthetic LXR Agonist Is More Effective than Cholesterol Loading at Inducing ABCA1 mRNA and Stimulating Cholesterol Efflux

Sparrow, Carl P ; Baffic, Joanne ; Lam, My-Hanh ; Lund, Erik G ; Adams, Alan D ; Fu, Xuan ; Hayes, Nancy ; Jones, A. Brian ; Macnaul, Karen L ; Ondeyka, John ; Singh, Sheo ; Wang, Jianhua ; Zhou, Gaochao ; Moller, David E ; Wright, Samuel D ; Menke, John G

The Journal of biological chemistry, 2002-03-22, Vol.277 (12), p.10021-10027 [Peer Reviewed Journal]

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5
Dual Mechanisms of ABCA1 Regulation by Geranylgeranyl Pyrophosphate
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Dual Mechanisms of ABCA1 Regulation by Geranylgeranyl Pyrophosphate

Gan, Xiaodong ; Kaplan, Rebecca ; Menke, John G ; MacNaul, Karen ; Chen, Yuli ; Sparrow, Carl P ; Zhou, Gaochao ; Wright, Samuel D ; Cai, Tian-Quan

The Journal of biological chemistry, 2001-12-28, Vol.276 (52), p.48702-48708 [Peer Reviewed Journal]

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6
Simvastatin Has Anti-Inflammatory and Antiatherosclerotic Activities Independent of Plasma Cholesterol Lowering
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Simvastatin Has Anti-Inflammatory and Antiatherosclerotic Activities Independent of Plasma Cholesterol Lowering

Sparrow, Carl P ; Burton, Charlotte A ; Hernandez, Melba ; Mundt, Steven ; Hassing, Heide ; Patel, Sushma ; Rosa, Ray ; Hermanowski-Vosatka, Anne ; Wang, Pei-Ran ; Zhang, Donghui ; Peterson, Larry ; Detmers, Patricia A ; Chao, Yu-Sheng ; Wright, Samuel D

Arteriosclerosis, thrombosis, and vascular biology, 2001-01, Vol.21 (1), p.115-121 [Peer Reviewed Journal]

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7
Measurement of fractional synthetic rates of multiple protein analytes by triple quadrupole mass spectrometry
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Measurement of fractional synthetic rates of multiple protein analytes by triple quadrupole mass spectrometry

Lee, Anita Y H ; Yates, Nathan A ; Ichetovkin, Marina ; Deyanova, Ekaterina ; Southwick, Katie ; Fisher, Timothy S ; Wang, Weixun ; Loderstedt, James ; Walker, Nykia ; Zhou, Haihong ; Zhao, Xuemei ; Sparrow, Carl P ; Hubbard, Brian K ; Rader, Daniel J ; Sitlani, Ayesha ; Millar, John S ; Hendrickson, Ronald C

Clinical chemistry (Baltimore, Md.), 2012-03, Vol.58 (3), p.619-627

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8
Cholesterol Efflux Potential and Antiinflammatory Properties of High-Density Lipoprotein After Treatment With Niacin or Anacetrapib
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Cholesterol Efflux Potential and Antiinflammatory Properties of High-Density Lipoprotein After Treatment With Niacin or Anacetrapib

Yvan-Charvet, Laurent ; Kling, Jelena ; Pagler, Tamara ; Li, Hongna ; Hubbard, Brian ; Fisher, Tim ; Sparrow, Carl P ; Taggart, Andrew K ; Tall, Alan R

Arteriosclerosis, thrombosis, and vascular biology, 2010-07, Vol.30 (7), p.1430-1438 [Peer Reviewed Journal]

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9
Cellular Oxidative Modification of Low Density Lipoprotein Does not Require Lipoxygenases
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Cellular Oxidative Modification of Low Density Lipoprotein Does not Require Lipoxygenases

Carl P. Sparrow ; Joanne Olszewski

Proceedings of the National Academy of Sciences - PNAS, 1992-01-01, Vol.89 (1), p.128-131

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10
A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo
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A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo

Ni, Yan G ; Di Marco, Stefania ; Condra, Jon H ; Peterson, Laurence B ; Wang, Weirong ; Wang, Fubao ; Pandit, Shilpa ; Hammond, Holly A ; Rosa, Ray ; Cummings, Richard T ; Wood, Dana D ; Liu, Xiaomei ; Bottomley, Matthew J ; Shen, Xun ; Cubbon, Rose M ; Wang, Sheng-ping ; Johns, Douglas G ; Volpari, Cinzia ; Hamuro, Lora ; Chin, Jayne ; Huang, Lingyi ; Zhao, Jing Zhang ; Vitelli, Salvatore ; Haytko, Peter ; Wisniewski, Douglas ; Mitnaul, Lyndon J ; Sparrow, Carl P ; Hubbard, Brian ; Carfí, Andrea ; Sitlani, Ayesha

Journal of lipid research, 2011-01, Vol.52 (1), p.78-86 [Peer Reviewed Journal]

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11
Biphenyl-Substituted Oxazolidinones as Cholesteryl Ester Transfer Protein Inhibitors: Modifications of the Oxazolidinone Ring Leading to the Discovery of Anacetrapib
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Biphenyl-Substituted Oxazolidinones as Cholesteryl Ester Transfer Protein Inhibitors: Modifications of the Oxazolidinone Ring Leading to the Discovery of Anacetrapib

Smith, Cameron J ; Ali, Amjad ; Hammond, Milton L ; Li, Hong ; Lu, Zhijian ; Napolitano, Joann ; Taylor, Gayle E ; Thompson, Christopher F ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Cumiskey, Anne-Marie ; Latham, Melanie ; Peterson, Laurence B ; Rosa, Ray ; Pivnichny, James V ; Tong, Xinchun ; Xu, Suoyu S ; Sinclair, Peter J

Journal of medicinal chemistry, 2011-07-14, Vol.54 (13), p.4880-4895 [Peer Reviewed Journal]

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12
An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes
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An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes

Zhang, Liwen ; McCabe, Timothy ; Condra, Jon H ; Ni, Yan G ; Peterson, Laurence B ; Wang, Weirong ; Strack, Alison M ; Wang, Fubao ; Pandit, Shilpa ; Hammond, Holly ; Wood, Dana ; Lewis, Dale ; Rosa, Ray ; Mendoza, Vivienne ; Cumiskey, Anne Marie ; Johns, Douglas G ; Hansen, Barbara C ; Shen, Xun ; Geoghagen, Neil ; Jensen, Kristian ; Zhu, Lei ; Wietecha, Karol ; Wisniewski, Douglas ; Huang, Lingyi ; Zhao, Jing Zhang ; Ernst, Robin ; Hampton, Richard ; Haytko, Peter ; Ansbro, Frances ; Chilewski, Shannon ; Chin, Jayne ; Mitnaul, Lyndon J ; Pellacani, Andrea ; Sparrow, Carl P ; An, Zhiqiang ; Strohl, William ; Hubbard, Brian ; Plump, Andrew S ; Blom, Daniel ; Sitlani, Ayesha

International journal of biological sciences, 2012, Vol.8 (3), p.310-327 [Peer Reviewed Journal]

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13
Different roles of liver X receptor α and β in lipid metabolism: Effects of an α-selective and a dual agonist in mice deficient in each subtype
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Different roles of liver X receptor α and β in lipid metabolism: Effects of an α-selective and a dual agonist in mice deficient in each subtype

Lund, Erik G ; Peterson, Laurence B ; Adams, Alan D ; Lam, My-Hanh N ; Burton, Charlotte A ; Chin, Jayne ; Guo, Qiu ; Huang, Shaei ; Latham, Melanie ; Lopez, Jacqueline C ; Menke, John G ; Milot, Denise P ; Mitnaul, Lyndon J ; Rex-Rabe, Sandra E ; Rosa, Raymond L ; Tian, Jenny Y ; Wright, Samuel D ; Sparrow, Carl P

Biochemical pharmacology, 2006, Vol.71 (4), p.453-463 [Peer Reviewed Journal]

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14
Functional analysis of sites within PCSK9 responsible for hypercholesterolemia
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Functional analysis of sites within PCSK9 responsible for hypercholesterolemia

Pandit, Shilpa ; Wisniewski, Doug ; Santoro, Joseph C ; Ha, Sookhee ; Ramakrishnan, Vijayalakshmi ; Cubbon, Rose M ; Cummings, Richard T ; Wright, Samuel D ; Sparrow, Carl P ; Sitlani, Ayesha ; Fisher, Timothy S

Journal of lipid research, 2008-06, Vol.49 (6), p.1333-1343 [Peer Reviewed Journal]

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15
Liver X Receptor Agonists as Potential Therapeutic Agents for Dyslipidemia and Atherosclerosis
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Liver X Receptor Agonists as Potential Therapeutic Agents for Dyslipidemia and Atherosclerosis

Lund, Erik G ; Menke, John G ; Sparrow, Carl P

Arteriosclerosis, thrombosis, and vascular biology, 2003-07, Vol.23 (7), p.1169-1177 [Peer Reviewed Journal]

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16
2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety
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2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety

Smith, Cameron J ; Ali, Amjad ; Chen, Liya ; Hammond, Milton L ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (1), p.346-349 [Peer Reviewed Journal]

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17
2-Arylbenzoxazoles as CETP inhibitors: Raising HDL-C in cynoCETP transgenic mice
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2-Arylbenzoxazoles as CETP inhibitors: Raising HDL-C in cynoCETP transgenic mice

Kallashi, Florida ; Kim, Dooseop ; Kowalchick, Jennifer ; Park, You Jung ; Hunt, Julianne A ; Ali, Amjad ; Smith, Cameron J ; Hammond, Milton L ; Pivnichny, James V ; Tong, Xinchun ; Xu, Suoyu S ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Cumiskey, Anne-Marie ; Latham, Melanie ; Peterson, Laurence B ; Rosa, Raymond ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.558-561 [Peer Reviewed Journal]

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18
Activation of PPARδ alters lipid metabolism in db/db mice
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Activation of PPARδ alters lipid metabolism in db/db mice

Leibowitz, Mark D ; Fiévet, Catherine ; Hennuyer, Nathalie ; Peinado-Onsurbe, Julia ; Duez, Hélène ; Berger, Joel ; Cullinan, Catherine A ; Sparrow, Carl P ; Baffic, Joanne ; Berger, Gregory D ; Santini, Conrad ; Marquis, Robert W ; Tolman, Richard L ; Smith, Roy G ; Moller, David E ; Auwerx, Johan

FEBS letters, 2000, Vol.473 (3), p.333-336 [Peer Reviewed Journal]

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19
Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis
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Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis

Strack, Alison M ; Carballo-Jane, Ester ; Wang, Sheng-Ping ; Xue, Jiyan ; Ping, Xiaoli ; McNamara, Lesley Ann ; Thankappan, Anil ; Price, Olga ; Wolff, Michael ; Wu, T J ; Kawka, Douglas ; Mariano, Michele ; Burton, Charlotte ; Chang, Ching H ; Chen, Jing ; Menke, John ; Luell, Silvi ; Zycband, Emanuel I ; Tong, Xinchun ; Raubertas, Richard ; Sparrow, Carl P ; Hubbard, Brian ; Woods, John ; O'Neill, Gary ; Waters, M Gerard ; Sitlani, Ayesha

Journal of lipid research, 2013-01, Vol.54 (1), p.177-188 [Peer Reviewed Journal]

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20
2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Attenuation of hERG binding and improved HDLc-raising efficacy
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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Attenuation of hERG binding and improved HDLc-raising efficacy

Sweis, Ramzi F ; Hunt, Julianne A ; Sinclair, Peter J ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Cumiskey, Anne-Marie ; Latham, Melanie ; Rosa, Raymond ; Peterson, Larry ; Sparrow, Carl P ; Anderson, Matt S

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (9), p.2597-2600 [Peer Reviewed Journal]

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21
2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Scaffold design and advancement in HDLc-raising efficacy
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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Scaffold design and advancement in HDLc-raising efficacy

Sweis, Ramzi F ; Hunt, Julianne A ; Kallashi, Florida ; Hammond, Milton L ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Cumiskey, Anne-Marie ; Latham, Melanie ; Rosa, Raymond ; Peterson, Larry ; Sparrow, Carl P ; Wright, Samuel D ; Anderson, Matt S ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (6), p.1890-1895 [Peer Reviewed Journal]

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22
SAR studies on the central phenyl ring of substituted biphenyl oxazolidinone-potent CETP inhibitors
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SAR studies on the central phenyl ring of substituted biphenyl oxazolidinone-potent CETP inhibitors

Lu, Zhijian ; Chen, Yi-heng ; Napolitano, Joann B ; Taylor, Gayle ; Ali, Amjad ; Hammond, Milton L ; Deng, Qiaolin ; Tan, Eugene ; Tong, Xinchun ; Xu, Suoyu S ; Latham, Melanie J ; Peterson, Laurence B ; Anderson, Matt S ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Chen, Ying ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.199-203 [Peer Reviewed Journal]

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23
2-Arylbenzoxazoles as CETP inhibitors: Substitution and modification of the α-alkoxyamide moiety
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2-Arylbenzoxazoles as CETP inhibitors: Substitution and modification of the α-alkoxyamide moiety

Hunt, Julianne A ; Gonzalez, Silvia ; Kallashi, Florida ; Hammond, Milton L ; Pivnichny, James V ; Tong, Xinchun ; Xu, Suoyu S ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.1019-1022 [Peer Reviewed Journal]

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24
Design of a novel class of biphenyl CETP inhibitors
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Design of a novel class of biphenyl CETP inhibitors

Lu, Zhijian ; Napolitano, Joann B ; Theberge, Ashleigh ; Ali, Amjad ; Hammond, Milton L ; Tan, Eugene ; Tong, Xinchun ; Xu, Suoyu S ; Latham, Melanie J ; Peterson, Laurence B ; Anderson, Matt S ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Chen, Ying ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2010-12, Vol.20 (24), p.7469-7472 [Peer Reviewed Journal]

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25
Reconstituted HDL Elicits Marked Changes in Plasma Lipids Following Single-Dose Injection in C57Bl/6 Mice
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Reconstituted HDL Elicits Marked Changes in Plasma Lipids Following Single-Dose Injection in C57Bl/6 Mice

Chen, Zhu ; O'Neill, Edward A ; Meurer, Roger D ; Gagen, Karen ; Luell, Silvi ; Wang, Sheng-Ping ; Ichetovkin, Marina ; Frantz-Wattley, Betsy ; Eveland, Suzanne ; Strack, Alison M ; Fisher, Timothy S ; Johns, Douglas G ; Sparrow, Carl P ; Wright, Samuel D ; Hubbard, Brian K ; Carballo-Jane, Ester

Journal of cardiovascular pharmacology and therapeutics, 2012-09, Vol.17 (3), p.315-323

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26
Cholesterol Efflux Potential and Anti-inflammatory Properties of HDL following Treatment with Niacin or Anacetrapib
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Cholesterol Efflux Potential and Anti-inflammatory Properties of HDL following Treatment with Niacin or Anacetrapib

Yvan-Charvet, Laurent ; Kling, Jelena ; Pagler, Tamara ; Li, Hongna ; Hubbard, Brian ; Fisher, Tim ; Sparrow, Carl P ; Taggart, Andrew K ; Tall, Alan R

Arteriosclerosis, thrombosis, and vascular biology, 2010-07, Vol.30 (7), p.1430-1438 [Peer Reviewed Journal]

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27
Deficiency in Inducible Nitric Oxide Synthase Results in Reduced Atherosclerosis in Apolipoprotein E-Deficient Mice
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Deficiency in Inducible Nitric Oxide Synthase Results in Reduced Atherosclerosis in Apolipoprotein E-Deficient Mice

Detmers, Patricia A ; Hernandez, Melba ; Mudgett, John ; Hassing, Heide ; Burton, Charlotte ; Mundt, Steven ; Chun, Sam ; Fletcher, Dan ; Card, Deborah J ; Lisnock, JeanMarie ; Weikel, Renee ; Bergstrom, James D ; Shevell, Diane E ; Hermanowski-Vosatka, Anne ; Sparrow, Carl P ; Chao, Yu-Sheng ; Rader, Daniel J ; Wright, Samuel D ; Pure, Ellen

The Journal of immunology (1950), 2000-09-15, Vol.165 (6), p.3430-3435 [Peer Reviewed Journal]

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28
Infectious Agents Are Not Necessary for Murine Atherogenesis
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Infectious Agents Are Not Necessary for Murine Atherogenesis

Wright, Samuel D ; Burton, Charlotte ; Hernandez, Melba ; Hassing, Heide ; Montenegro, Judy ; Mundt, Steve ; Patel, Sushma ; Card, Deborah J ; Hermanowski-Vosatka, Anne ; Bergstrom, James D ; Sparrow, Carl P ; Detmers, Patricia A ; Chao, Yu-Sheng

The Journal of experimental medicine, 2000-04-17, Vol.191 (8), p.1437-1442 [Peer Reviewed Journal]

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29
Corrigendum to “2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety” [Bioorg. Med. Chem. Lett. 20 (2010) 346]
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Corrigendum to “2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety” [Bioorg. Med. Chem. Lett. 20 (2010) 346]

Smith, Cameron J ; Ali, Amjad ; Chen, Liya ; Hammond, Milton L ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (24), p.7555-7555 [Peer Reviewed Journal]

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30
A high-precision fluorogenic cholesteryl ester transfer protein assay compatible with animal serum and 3456-well assay technology
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A high-precision fluorogenic cholesteryl ester transfer protein assay compatible with animal serum and 3456-well assay technology

Eveland, Suzanne S ; Milot, Denise P ; Guo, Qiu ; Chen, Ying ; Hyland, Sheryl A ; Peterson, Laurence B ; Jezequel-Sur, Sylvie ; O’Donnell, Gregory T ; Zuck, Paul D ; Ferrer, Marc ; Strulovici, Berta ; Wagner, John A ; Tanaka, Wesley K ; Hilliard, Deborah A ; Laterza, Omar ; Wright, Samuel D ; Sparrow, Carl P ; Anderson, Matt S

Analytical biochemistry, 2007, Vol.368 (2), p.239-249 [Peer Reviewed Journal]

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31
Discovery of Substituted Biphenyl Oxazolidinone Inhibitors of Cholesteryl Ester Transfer Protein
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Discovery of Substituted Biphenyl Oxazolidinone Inhibitors of Cholesteryl Ester Transfer Protein

Thompson, Christopher F ; Ali, Amjad ; Quraishi, Nazia ; Lu, Zhijian ; Hammond, Milton L ; Sinclair, Peter J ; Anderson, Matt S ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D

ACS medicinal chemistry letters, 2011-06-09, Vol.2 (6), p.424-427 [Peer Reviewed Journal]

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32
Fluorogenic substrates for high-throughput measurements of endothelial lipase activity
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Fluorogenic substrates for high-throughput measurements of endothelial lipase activity

Mitnaul, Lyndon J ; Tian, Jenny ; Burton, Charlotte ; Lam, My-Hanh ; Zhu, Yuping ; Olson, Steve H ; Schneeweis, Jonathan E ; Zuck, Paul ; Pandit, Shilpa ; Anderson, Matt ; Maletic, Milana M ; Waddell, Sherman T ; Wright, Samuel D ; Sparrow, Carl P ; Lund, Erik G

Journal of lipid research, 2007-02, Vol.48 (2), p.472-482 [Peer Reviewed Journal]

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33
A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo1[S]
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A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo1[S]

Ni, Yan G ; Di Marco, Stefania ; Condra, Jon H ; Peterson, Laurence B ; Wang, Weirong ; Wang, Fubao ; Pandit, Shilpa ; Hammond, Holly A ; Rosa, Ray ; Cummings, Richard T ; Wood, Dana D ; Liu, Xiaomei ; Bottomley, Matthew J ; Shen, Xun ; Cubbon, Rose M ; Wang, Sheng-ping ; Johns, Douglas G ; Volpari, Cinzia ; Hamuro, Lora ; Chin, Jayne ; Huang, Lingyi ; Zhao, Jing Zhang ; Vitelli, Salvatore ; Haytko, Peter ; Wisniewski, Douglas ; Mitnaul, Lyndon J ; Sparrow, Carl P ; Hubbard, Brian ; Carfí, Andrea ; Sitlani, Ayesha

Journal of lipid research, 2011-01, Vol.52 (1), p.78-86 [Peer Reviewed Journal]

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