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1
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Article
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Practical approaches to incurred sample LC-MS/MS reanalysis: confirming unexpected results

Li, Wenkui ; Lin, Hui ; Flarakos, Jimmy ; Tse, Francis L S

Analytical chemistry, 19 February 2013, Vol.85(4), pp.2405-13 [Peer Reviewed Journal]

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2
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Strategies in quantitative LC-MS/MS analysis of unstable small molecules in biological matrices

Li, Wenkui ; Zhang, Jie ; Tse, Francis L S

Biomedical chromatography : BMC, January 2011, Vol.25(1-2), pp.258-77 [Peer Reviewed Journal]

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3
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Quantitative analysis of pasireotide (SOM230), a cyclic peptide, in monkey plasma using liquid chromatography in combination with tandem mass spectrometry

Fu, Yunlin ; Li, Wenkui ; Flarakos, Jimmy ; Tse, Francis L S

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 01 January 2016, Vol.1008, pp.242-249 [Peer Reviewed Journal]

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4
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A semi-automated LC-MS/MS method for the determination of LCI699, a steroid 11β-hydroxylase inhibitor, in human plasma

Li, Wenkui ; Luo, Suyi ; Rebello, Sam ; Flarakos, Jimmy ; Tse, Francis L S

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 01 June 2014, Vol.960, pp.182-93 [Peer Reviewed Journal]

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5
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LC-MS/MS bioanalysis of loratadine (Claritin) in dried blood spot (DBS) samples collected by subjects in a clinical research study

Li, Wenkui ; Doherty, John ; Moench, Paul ; Flarakos, Jimmy ; Tse, Francis L S

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 01 March 2015, Vol.983-984, pp.117-24 [Peer Reviewed Journal]

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6
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Quantitative analysis of NIM811, a cyclophilin inhibitor, in human dried blood spots using liquid chromatography-tandem mass spectrometry

Li, Wenkui ; Williams, Shannon M ; Smith, Harold T ; Tse, Francis L S

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 15 August 2011, Vol.879(24), pp.2376-82 [Peer Reviewed Journal]

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7
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Developing a robust ultrafiltration-LC-MS/MS method for quantitative analysis of unbound vadimezan (ASA404) in human plasma

Li, Wenkui ; Lin, Hui ; Smith, Harold T ; Tse, Francis L S

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 01 July 2011, Vol.879(21), pp.1927-33 [Peer Reviewed Journal]

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8
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Evaluation of plasma microsampling for dried plasma spots (DPS) in quantitative LC-MS/MS bioanalysis using ritonavir as a model compound

Li, Wenkui ; Doherty, John ; Favara, Sarah ; Breen, Christopher ; Flarakos, Jimmy ; Tse, Francis L S

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 01 June 2015, Vol.991, pp.46-52 [Peer Reviewed Journal]

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9
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Supported liquid extraction in combination with LC‐MS/MS for high‐throughput quantitative analysis of hydrocortisone in mouse serum

Wu, Shari ; Li, Wenkui ; Mujamdar, Tapan ; Smith, Tom ; Bryant, Matthew ; Tse, Francis L. S.

Biomedical Chromatography, June 2010, Vol.24(6), pp.632-638 [Peer Reviewed Journal]

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10
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Quantitative determination of BAF312, a S1P-R modulator, in human urine by LC-MS/MS: prevention and recovery of lost analyte due to container surface adsorption

Li, Wenkui ; Luo, Suyi ; Smith, Harold T ; Tse, Francis L S

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 15 February 2010, Vol.878(5-6), pp.583-9 [Peer Reviewed Journal]

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11
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Differential Mobility Spectrometry Coupled with Multiple Ion Monitoring in Regulated LC-MS/MS Bioanalysis of a Therapeutic Cyclic Peptide in Human Plasma

Fu, Yunlin ; Xia, Yuan-Qing ; Flarakos, Jimmy ; Tse, Francis L S ; Miller, Jeffrey D ; Jones, Elliott B ; Li, Wenkui

Analytical chemistry, 05 April 2016, Vol.88(7), pp.3655-61 [Peer Reviewed Journal]

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12
LC−MS/MS Approach for Quantification of Therapeutic Proteins in Plasma Using a Protein Internal Standard and 2D-Solid-Phase Extraction Cleanup
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LC−MS/MS Approach for Quantification of Therapeutic Proteins in Plasma Using a Protein Internal Standard and 2D-Solid-Phase Extraction Cleanup

Yang, Ziping ; Hayes, Michael ; Fang, Xinping ; Daley, Michael P. ; Ettenberg, Seth ; Tse, Francis L. S.

Analytical Chemistry, 12/2007, Vol.79(24), pp.9294-9301 [Peer Reviewed Journal]

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13
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Article
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LC-MS/MS approach for quantification of therapeutic proteins in plasma using a protein internal standard and 2D-solid-phase extraction cleanup

Yang, Ziping ; Hayes, Michael ; Fang, Xinping ; Daley, Michael P ; Ettenberg, Seth ; Tse, Francis L S

Analytical chemistry, 15 December 2007, Vol.79(24), pp.9294-301 [Peer Reviewed Journal]

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14
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Toxicokinetic assessment of methylphenidate (Ritalin ® ) enantiomers in pregnant rats and rabbits

Bakhtiar, Ray ; Tse, Francis L. S.

Biomedical Chromatography, June 2004, Vol.18(5), pp.275-281 [Peer Reviewed Journal]

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15
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Toxicokinetic assessment of methylphenidate (Ritalin®) in a 13‐week oral (gavage) toxicity study in rats using an enantiomeric liquid chromatography/tandem mass spectrometry assay

Bakhtiar, Ray ; Tse, Francis L. S.

Rapid Communications in Mass Spectrometry, 30 September 2003, Vol.17(18), pp.2160-2162 [Peer Reviewed Journal]

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16
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Toxicokinetic assessment of methylphenidate (Ritalin ® ) in a 13‐week oral toxicity study in dogs

Bakhtiar, Ray ; Ramos, Luis ; Tse, Francis L. S.

Biomedical Chromatography, January 2004, Vol.18(1), pp.45-50 [Peer Reviewed Journal]

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17
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Rapid analysis of MMI270B, an inhibitor of matrix metalloproteases in human plasma by liquid chromatography–tandem mass spectrometry: matrix interference in patient samples

Majumdar, Tapan K. ; Vedananda, Sunanda ; Tse, Francis L. S.

Biomedical Chromatography, March 2004, Vol.18(2), pp.77-85 [Peer Reviewed Journal]

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18
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Article
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Rapid analysis of MMI270B, an inhibitor of matrix metalloproteases in human plasma by liquid chromatography-tandem mass spectrometry: matrix interference in patient samples

Majumdar, Tapan K ; Vedananda, Sunanda ; Tse, Francis L S

Biomedical chromatography : BMC, March 2004, Vol.18(2), pp.77-85 [Peer Reviewed Journal]

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19
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Article
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Quantification of methylphenidate (Ritalin ® ) in rabbit fetal tissue using a chiral liquid chromatography/tandem mass spectrometry assay

Bakhtiar, Ray ; Ramos, Luis ; Tse, Francis L. S.

Rapid Communications in Mass Spectrometry, 15 January 2002, Vol.16(1), pp.81-83 [Peer Reviewed Journal]

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20
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A sensitive and high-throughput LC-MS/MS method for the quantification of pegylated-interferon-alpha2a in human serum using monolithic C18 solid phase extraction for enrichment

Yang, Ziping ; Ke, June ; Hayes, Michael ; Bryant, Matthew ; Tse, Francis L S

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 15 June 2009, Vol.877(18-19), pp.1737-42 [Peer Reviewed Journal]

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21
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Juvenile toxicity assessment of d,l‐methylphenidate in rats

Beckman, David A. ; Schneider, Marilynn ; Youreneff, Maureen ; Tse, Francis L. S.

Birth Defects Research Part B: Developmental and Reproductive Toxicology, February 2008, Vol.83(1), pp.48-67 [Peer Reviewed Journal]

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22
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Developmental toxicity assessment of d,l‐Methylphenidate and d‐Methylphenidate in rats and rabbits

Beckman, David A. ; Schneider, Marilynn ; Youreneff, Maureen ; Tse, Francis L. S.

Birth Defects Research Part B: Developmental and Reproductive Toxicology, October 2008, Vol.83(5), pp.489-501 [Peer Reviewed Journal]

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23
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Determination of LAG078, a lipid-lowering compound, in dog plasma using liquid chromatography-tandem mass spectrometry: application in a toxicokinetic study

Majumdar, Tapan K ; Wu, Shari ; Vedananda, Sunanda ; Tse, Francis L S

Journal of pharmaceutical and biomedical analysis, 29 June 2004, Vol.35(4), pp.853-66 [Peer Reviewed Journal]

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24
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High‐throughput semi‐automated 96‐well liquid/liquid extraction and liquid chromatography/mass spectrometric analysis of everolimus (RAD 001) and cyclosporin a (CsA) in whole blood

Brignol, Nastry ; Mcmahon, Louis M. ; Luo, Suyi ; Tse, Francis L. S.

Rapid Communications in Mass Spectrometry, 30 June 2001, Vol.15(12), pp.898-907 [Peer Reviewed Journal]

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25
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Brain uptake of dihydroergotamine after intravenous and nasal administration in the rat

Wang, Yanfeng ; Aun, Renee ; Tse, Francis L. S.

Biopharmaceutics & Drug Disposition, December 1998, Vol.19(9), pp.571-575 [Peer Reviewed Journal]

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26
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Simultaneous determination of midazolam and 1′‐hydroxymidazolam in human plasma by liquid chromatography with tandem mass spectrometry

Li, Wenkui ; Luo, Suyi ; Smith, Harold T. ; Tse, Francis L. S.

Biomedical Chromatography, August 2007, Vol.21(8), pp.841-851 [Peer Reviewed Journal]

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27
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Determination of N-methyl-4-isoleucine-cyclosporin (NIM811) in human whole blood by high performance liquid chromatography-tandem mass spectrometry

Li, Wenkui ; Luo, Suyi ; Hayes, Michael ; He, Handan ; Tse, Francis L S

Biomedical chromatography : BMC, March 2007, Vol.21(3), pp.249-56 [Peer Reviewed Journal]

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28
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Determination of N ‐methyl‐4‐isoleucine‐cyclosporin (NIM811) in human whole blood by high performance liquid chromatography‐tandem mass spectrometry

Li, Wenkui ; Luo, Suyi ; Hayes, Michael ; He, Handan ; Tse, Francis L. S.

Biomedical Chromatography, March 2007, Vol.21(3), pp.249-256 [Peer Reviewed Journal]

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29
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High-throughput determination of ultra-low concentrations of LAG078, a lipid modulator, in human plasma

Majumdar, Tapan K ; Bakhtiar, Ray ; Chen, Cindy ; Ramos, Luis ; Tse, Francis L S

Journal of pharmaceutical and biomedical analysis, 29 April 2005, Vol.37(5), pp.1039-48 [Peer Reviewed Journal]

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30
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Trace‐level quantitation of iralukast in human plasma by microbore liquid chromatography/tandem mass spectrometry

Majumdar, Tapan K. ; Bakhtiar, Ray ; Melamed, David ; Tse, Francis L. S.

Rapid Communications in Mass Spectrometry, 31 March 2000, Vol.14(6), pp.476-481 [Peer Reviewed Journal]

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31
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Article
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High‐throughput analysis of everolimus (RAD001) and cyclosporin A (CsA) in whole blood by liquid chromatography/mass spectrometry using a semi‐automated 96‐well solid‐phase extraction system

Mcmahon, Louis M. ; Luo, Suyi ; Hayes, Michael ; Tse, Francis L. S.

Rapid Communications in Mass Spectrometry, 15 November 2000, Vol.14(21), pp.1965-1971 [Peer Reviewed Journal]

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32
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Article
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Determination of terbinafine (Lamisil®) in human hair by microbore liquid chromatography/tandem mass spectrometry

Majumdar, Tapan K. ; Bakhtiar, Ray ; Melamed, David ; Tse, Francis L. S.

Rapid Communications in Mass Spectrometry, 30 July 2000, Vol.14(14), pp.1214-1219 [Peer Reviewed Journal]

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33
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Absorption and disposition of a tripeptoid and a tetrapeptide in the rat

Wang, Yanfeng ; Lin, Hanford ; Tullman, Robert ; Jewell, Charles F. ; Weetall, Marla L. ; Tse, Francis L. S.

Biopharmaceutics & Drug Disposition, March 1999, Vol.20(2), pp.69-75 [Peer Reviewed Journal]

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34
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Simultaneous determination of ribavirin and ribavirin base in monkey plasma by high performance liquid chromatography with tandem mass spectrometry

Li, Wenkui ; Luo, Suyi ; Li, Shaoyong ; Athill, Lawrence ; Wu, Amy ; Ray, Tapan ; Zhou, Wei ; Ke, June ; Smith, Harold T ; Tse, Francis L S

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 01 February 2007, Vol.846(1-2), pp.57-68 [Peer Reviewed Journal]

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35
Handbook of LC-MS Bioanalysis: Best Practices, Experimental Protocols, and Regulations.
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Book
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Handbook of LC-MS Bioanalysis: Best Practices, Experimental Protocols, and Regulations.

Li, Wenkui. Zhang, Jie. ; Tse, Francis L. S.

1st ed..

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36
Material Type:
Review
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Dried blood spot sampling in combination with LC‐MS/MS for quantitative analysis of small molecules

Li, Wenkui ; Tse, Francis L. S. Srinivas, Nuggehally R.

Biomedical Chromatography, January 2010, Vol.24(1), pp.49-65 [Peer Reviewed Journal]

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