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Reverse cope elimination of hydroxylamines and alkenes or alkynes: theoretical investigation of tether length and substituent effects

Krenske, Elizabeth H ; Davison, Edwin C ; Forbes, Ian T ; Warner, Jacqueline A ; Smith, Adrian L ; Holmes, Andrew B ; Houk, K N

Journal of the American Chemical Society, 01 February 2012, Vol.134(4), pp.2434-41 [Peer Reviewed Journal]

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A Critical Role for MAPK Signalling Pathways in the Transcriptional Regulation of Toll Like Receptors

Peroval, Marylene Y ; Boyd, Amy C ; Young, John R ; Smith, Adrian L Gay, Nick (editor)

PLoS ONE, 2013, Vol.8(2) [Peer Reviewed Journal]

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Harnessing single cell sorting to identify cell division genes and regulators in bacteria

Burke, Catherine ; Liu, Michael ; Britton, Warwick ; Triccas, James A ; Thomas, Torsten ; Smith, Adrian L ; Allen, Steven ; Salomon, Robert ; Harry, Elizabeth

PloS one, 2013, Vol.8(4), pp.e60964 [Peer Reviewed Journal]

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Monitoring chicken flock behaviour provides early warning of infection by human pathogen Campylobacter

Colles, Frances M ; Cain, Russell J ; Nickson, Thomas ; Smith, Adrian L ; Roberts, Stephen J ; Maiden, Martin C J ; Lunn, Daniel ; Dawkins, Marian Stamp

Proceedings. Biological sciences, 13 January 2016, Vol.283(1822) [Peer Reviewed Journal]

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A genetic linkage map for the apicomplexan protozoan parasite Eimeria maxima and comparison with Eimeria tenella

Blake, Damer P ; Oakes, Richard ; Smith, Adrian L

International Journal for Parasitology, February 2011, Vol.41(2), pp.263-270 [Peer Reviewed Journal]

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Transient and Prolonged Response of Chicken Cecum Mucosa to Colonization with Different Gut Microbiota

Volf, Jiri ; Polansky, Ondrej ; Varmuzova, Karolina ; Gerzova, Lenka ; Sekelova, Zuzana ; Faldynova, Marcela ; Babak, Vladimir ; Medvecky, Matej ; Smith, Adrian L ; Kaspers, Bernd ; Velge, Philippe ; Rychlik, Ivan Prodinra, Archive Ouverte (Editor)

PLoS ONE, 2016, Vol.11(9), p.e0163932 [Peer Reviewed Journal]

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Clonal Structure of Rapid-Onset MDV-Driven CD4+ Lymphomas and Responding CD8+ T Cells (TCR Repertoire Analysis during Infection with MDV)

Mwangi, William N ; Smith, Lorraine P ; Baigent, Susan J ; Beal, Richard K ; Nair, Venugopal ; Smith, Adrian L Osterrieder, Nikolaus (Editor)

PLoS Pathogens, 2011, Vol.7(5), p.e1001337 [Peer Reviewed Journal]

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Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck

Flammer, Patrik G ; Dellicour, Simon ; Preston, Stephen G ; Rieger, Dirk ; Warren, Sylvia ; Tan, Cedric K W ; Nicholson, Rebecca ; Přichystalová, Renáta ; Bleicher, Niels ; Wahl, Joachim ; Faria, Nuno R ; Pybus, Oliver G ; Pollard, Mark ; Smith, Adrian L

Proceedings. Biological sciences, 03 October 2018, Vol.285(1888) [Peer Reviewed Journal]

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γδ T cells play a protective role during infection with Nippostrongylus brasiliensis by promoting goblet cell function in the small intestine

Inagaki‐Ohara, Kyoko ; Sakamoto, Yukiko ; Dohi, Taeko ; Smith, Adrian L.

Immunology, December 2011, Vol.134(4), pp.448-458 [Peer Reviewed Journal]

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The Cinderella syndrome: why do malaria-infected cells burst at midnight?

Mideo, Nicole ; Reece, Sarah E ; Smith, Adrian L ; Metcalf, C. Jessica E

Trends in Parasitology, January 2013, Vol.29(1), pp.10-16 [Peer Reviewed Journal]

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Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase

Sharbeen, George ; Yee, Christine W Y ; Smith, Adrian L ; Jolly, Christopher J

The Journal of experimental medicine, 07 May 2012, Vol.209(5), pp.965-74 [Peer Reviewed Journal]

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12
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Detection of Felis catus gammaherpesvirus 1 (FcaGHV1) in peripheral blood B- and T-lymphocytes in asymptomatic, naturally-infected domestic cats

Mcluckie, Alicia J ; Barrs, Vanessa R ; Smith, Adrian L ; Beatty, Julia A

Virology, October 2016, Vol.497, pp.211-216 [Peer Reviewed Journal]

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13
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Peyer's patches are required for the induction of rapid Th1 responses in the gut and mesenteric lymph nodes during an enteric infection

Kwa, Sue-Fen ; Beverley, Peter ; Smith, Adrian L

Journal of immunology (Baltimore, Md. : 1950), 15 June 2006, Vol.176(12), pp.7533-41 [Peer Reviewed Journal]

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Discovery of 1H-pyrazol-3(2H)-ones as potent and selective inhibitors of protein kinase R-like endoplasmic reticulum kinase (PERK)

Smith, Adrian L ; Andrews, Kristin L ; Beckmann, Holger ; Bellon, Steven F ; Beltran, Pedro J ; Booker, Shon ; Chen, Hao ; Chung, Young-Ah ; D'Angelo, Noel D ; Dao, Jennifer ; Dellamaggiore, Kenneth R ; Jaeckel, Peter ; Kendall, Richard ; Labitzke, Katja ; Long, Alexander M ; Materna-Reichelt, Silvia ; Mitchell, Petia ; Norman, Mark H ; Powers, David ; Rose, Mark ; Shaffer, Paul L ; Wu, Michelle M ; Lipford, J Russell

Journal of medicinal chemistry, 12 February 2015, Vol.58(3), pp.1426-41 [Peer Reviewed Journal]

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Genetic Mapping Identifies Novel Highly Protective Antigens for an Apicomplexan Parasite (Mapping Protective Apicomplexan Antigens)

Blake, Damer P ; Billington, Karen J ; Copestake, Susan L ; Oakes, Richard D ; Quail, Michael A ; Wan, Kiew-Lian ; Shirley, Martin W ; Smith, Adrian L Sibley, L. David (Editor)

PLoS Pathogens, 2011, Vol.7(2), p.e1001279 [Peer Reviewed Journal]

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Induction of lymphomas by inoculation of Marek's disease virus-derived lymphoblastoid cell lines: prevention by CVI988 vaccination

Mwangi, William N ; Smith, Lorraine P ; Baigent, Susan J ; Smith, Adrian L ; Nair, Venugopal

Avian Pathology, 01 December 2012, Vol.41(6), pp.589-598 [Peer Reviewed Journal]

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17
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Bovine γδ T cells are a major regulatory T cell subset

Guzman, Efrain ; Hope, Jayne ; Taylor, Geraldine ; Smith, Adrian L ; Cubillos-Zapata, Carolina ; Charleston, Bryan

Journal of immunology (Baltimore, Md. : 1950), 01 July 2014, Vol.193(1), pp.208-22 [Peer Reviewed Journal]

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The Enediyne Antibiotics
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The Enediyne Antibiotics

Smith, Adrian L. ; Nicolaou, K. C.

Journal of Medicinal Chemistry, 01/1996, Vol.39(11), pp.2103-2117 [Peer Reviewed Journal]

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19
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Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases

Smith, Adrian L ; D'Angelo, Noel D ; Bo, Yunxin Y ; Booker, Shon K ; Cee, Victor J ; Herberich, Brad ; Hong, Fang-Tsao ; Jackson, Claire L M ; Lanman, Brian A ; Liu, Longbin ; Nishimura, Nobuko ; Pettus, Liping H ; Reed, Anthony B ; Tadesse, Seifu ; Tamayo, Nuria A ; Wurz, Ryan P ; Yang, Kevin ; Andrews, Kristin L ; Whittington, Douglas A ; Mccarter, John D ; Miguel, Tisha San ; Zalameda, Leeanne ; Jiang, Jian ; Subramanian, Raju ; Mullady, Erin L ; Caenepeel, Sean ; Freeman, Daniel J ; Wang, Ling ; Zhang, Nancy ; Wu, Tian ; Hughes, Paul E ; Norman, Mark H

Journal of medicinal chemistry, 14 June 2012, Vol.55(11), pp.5188-219 [Peer Reviewed Journal]

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20
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Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511

Norman, Mark H ; Andrews, Kristin L ; Bo, Yunxin Y ; Booker, Shon K ; Caenepeel, Sean ; Cee, Victor J ; D'Angelo, Noel D ; Freeman, Daniel J ; Herberich, Bradley J ; Hong, Fang-Tsao ; Jackson, Claire L M ; Jiang, Jian ; Lanman, Brian A ; Liu, Longbin ; Mccarter, John D ; Mullady, Erin L ; Nishimura, Nobuko ; Pettus, Liping H ; Reed, Anthony B ; Miguel, Tisha San ; Smith, Adrian L ; Stec, Markian M ; Tadesse, Seifu ; Tasker, Andrew ; Aidasani, Divesh ; Zhu, Xiaochun ; Subramanian, Raju ; Tamayo, Nuria A ; Wang, Ling ; Whittington, Douglas A ; Wu, Bin ; Wu, Tian ; Wurz, Ryan P ; Yang, Kevin ; Zalameda, Leeanne ; Zhang, Nancy ; Hughes, Paul E

Journal of medicinal chemistry, 13 September 2012, Vol.55(17), pp.7796-816 [Peer Reviewed Journal]

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Correction to Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511
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Correction to Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511

Norman, Mark H. ; Andrews, Kristin L. ; Bo, Yunxin Y. ; Booker, Shon K. ; Caenepeel, Sean ; Cee, Victor J. ; D’angelo, Noel D. ; Freeman, Daniel J. ; Herberich, Bradley J. ; Hong, Fang-Tsao ; Jackson, Claire L. M. ; Jiang, Jian ; Lanman, Brian A. ; Liu, Longbin ; Mccarter, John D. ; Mullady, Erin L. ; Nishimura, Nobuko ; Pettus, Liping H. ; Reed, Anthony B. ; Miguel, Tisha San ; Smith, Adrian L. ; Stec, Markian M. ; Tadesse, Seifu ; Tasker, Andrew ; Aidasani, Divesh ; Zhu, Xiaochun ; Subramanian, Raju ; Tamayo, Nuria A. ; Wang, Ling ; Whittington, Douglas A. ; Wu, Bin ; Wu, Tian ; Wurz, Ryan P. ; Yang, Kevin ; Zalameda, Leeanne ; Zhang, Nancy ; Hughes, Paul E.

Journal of Medicinal Chemistry, 10/25/2012, Vol.55(20), pp.8975-8975 [Peer Reviewed Journal]

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22
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TLR15 is unique to avian and reptilian lineages and recognizes a yeast-derived agonist

Boyd, Amy C ; Peroval, Marylene Y ; Hammond, John A ; Prickett, Michael D ; Young, John R ; Smith, Adrian L

Journal of immunology (Baltimore, Md. : 1950), 15 November 2012, Vol.189(10), pp.4930-8 [Peer Reviewed Journal]

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23
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Badger macrophages fail to produce nitric oxide, a key anti-mycobacterial effector molecule

Bilham, Kirstin ; Boyd, Amy C ; Preston, Stephen G ; Buesching, Christina D ; Newman, Chris ; Macdonald, David W ; Smith, Adrian L

Scientific reports, 06 April 2017, Vol.7, pp.45470 [Peer Reviewed Journal]

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24
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Effects of Weather Conditions on Oxidative Stress, Oxidative Damage, and Antioxidant Capacity in a Wild-Living Mammal, the European Badger (Meles meles)

Bilham, Kirstin ; Newman, Chris ; Buesching, Christina D ; Noonan, Michael J ; Boyd, Amy ; Smith, Adrian L ; Macdonald, David W

Physiological and biochemical zoology : PBZ, 2018, Vol.91(4), pp.987-1004 [Peer Reviewed Journal]

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25
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Early pathogenesis during infectious bursal disease in susceptible chickens is associated with changes in B cell genomic methylation and loss of genome integrity

Ciccone, Nick A ; Smith, Lorraine P ; Mwangi, William ; Boyd, Amy ; Broadbent, Andrew J ; Smith, Adrian L ; Nair, Venugopal

Developmental and Comparative Immunology, August 2017, Vol.73, pp.169-174 [Peer Reviewed Journal]

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26
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Antigenic diversity in Eimeria maxima and the influence of host genetics and immunization schedule on cross-protective immunity

Smith, Adrian L ; Hesketh, Patricia ; Archer, Andrew ; Shirley, Martin W

Infection and immunity, May 2002, Vol.70(5), pp.2472-9 [Peer Reviewed Journal]

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27
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Traceless solid phase synthesis of 2,3-disubstituted indoles

Smith, Adrian L ; Stevenson, Graeme I ; Swain, Christopher J ; Castro, Josél

Tetrahedron Letters, 1998, Vol.39(45), pp.8317-8320 [Peer Reviewed Journal]

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28
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A Genetic and Functional Relationship between T Cells and Cellular Proliferation in the Adult Hippocampus

Huang, Guo-Jen ; Smith, Adrian L. ; Gray, Daniel H.D. ; Cosgrove, Cormac ; Singer, Benjamin H. ; Edwards, Andrew ; Sim, Stuart ; Parent, Jack M. ; Johnsen, Alyssa ; Mott, Richard ; Klenerman, Paul ; Flint, Jonathan ; Mathis, Diane J. ; Benoist, Christophe O.

Huang, Guo-Jen, Adrian L. Smith, Daniel H. D. Gray, Cormac Cosgrove, Benjamin H. Singer, Andrew Edwards, Stuart Sim, et al. 2010. A Genetic and Functional Relationship between T Cells and Cellular Proliferation in the Adult Hippocampus. PLoS Biology 8(12): e1000561. [Peer Reviewed Journal]

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29
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Regional and global changes in TCRαβ T cell repertoires in the gut are dependent upon the complexity of the enteric microflora

Mwangi, William N ; Beal, Richard K ; Powers, Claire ; Wu, Xikun ; Humphrey, Tom ; Watson, Michael ; Bailey, Michael ; Friedman, Aharon ; Smith, Adrian L

Developmental and Comparative Immunology, 2010, Vol.34(4), pp.406-417 [Peer Reviewed Journal]

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30
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Two CD1 genes map to the chicken MHC, indicating that CD1 genes are ancient and likely to have been present in the primordial MHC

Salomonsen, Jan ; Sørensen, Maria Rathmann ; Marston, Denise A ; Rogers, Sally L ; Collen, Trevor ; Van Hateren, Andrew ; Smith, Adrian L ; Beal, Richard K ; Skjødt, Karsten ; Kaufman, Jim

Proceedings of the National Academy of Sciences of the United States of America, 14 June 2005, Vol.102(24), pp.8668-73 [Peer Reviewed Journal]

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31
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Cloning and characterization of chicken IL-10 and its role in the immune response to Eimeria maxima

Rothwell, Lisa ; Young, John R ; Zoorob, Rima ; Whittaker, Catherine A ; Hesketh, Pat ; Archer, Andrew ; Smith, Adrian L ; Kaiser, Pete

Journal of immunology (Baltimore, Md. : 1950), 15 August 2004, Vol.173(4), pp.2675-82 [Peer Reviewed Journal]

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32
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Transient and Prolonged Response of Chicken Cecum Mucosa to Colonization with Different Gut Microbiota

Volf, Jiri ; Polansky, Ondrej ; Varmuzova, Karolina ; Gerzova, Lenka ; Sekelova, Zuzana ; Faldynova, Marcela ; Babak, Vladimir ; Medvecky, Matej ; Smith, Adrian L. ; Kaspers, Bernd ; Velge, Philippe ; Rychlik, Ivan

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33
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EmaxDB: Availability of a first draft genome sequence for the apicomplexan Eimeria maxima

Blake, Damer P ; Alias, Halimah ; Billington, Karen J ; Clark, Emily L ; Mat-Isa, Mohd-Noor ; Mohamad, Ahmad-Fuad-Hilmi ; Mohd-Amin, Mohd-Rashdi ; Tay, Yea-Ling ; Smith, Adrian L ; Tomley, Fiona M ; Wan, Kiew-Lian

Molecular & Biochemical Parasitology, July 2012, Vol.184(1), pp.48-51 [Peer Reviewed Journal]

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34
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Visualizing the Neutrophil Response to Sterile Tissue Injury in Mouse Dermis Reveals a Three-Phase Cascade of Events

Ng, Lai Guan ; Qin, Jim S ; Roediger, Ben ; Wang, Yilin ; Jain, Rohit ; Cavanagh, Lois L ; Smith, Adrian L ; Jones, Cheryl A ; de Veer, Michael ; Grimbaldeston, Michele A ; Meeusen, Els N ; Weninger, Wolfgang

Journal of Investigative Dermatology, October 2011, Vol.131(10), pp.2058-2068 [Peer Reviewed Journal]

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35
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Clearance of enteric Salmonella enterica serovar Typhimurium in chickens is independent of B-cell function

Beal, Richard K ; Powers, Claire ; Davison, T Fred ; Barrow, Paul A ; Smith, Adrian L

Infection and immunity, February 2006, Vol.74(2), pp.1442-4 [Peer Reviewed Journal]

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36
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A strong antigen-specific T-cell response is associated with age and genetically dependent resistance to avian enteric salmonellosis

Beal, Richard K ; Powers, Claire ; Wigley, Paul ; Barrow, Paul A ; Kaiser, Pete ; Smith, Adrian L

Infection and immunity, November 2005, Vol.73(11), pp.7509-16 [Peer Reviewed Journal]

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37
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Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization

Leggat, Jamie A ; Gibbons, Deena L ; Haque, Syeda F.Y ; Smith, Adrian L ; Wells, James W ; Choy, Katherine ; Lloyd, Clare M ; Hayday, Adrian C ; Noble, Alistair

The Journal of Allergy and Clinical Immunology, 2008, Vol.122(5), pp.1014-1021.e4 [Peer Reviewed Journal]

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38