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Conformational dynamics and role of the acidic pocket in ASIC pH-dependent gating

Vullo, Sabrina ; Bonifacio, Gaetano ; Roy, Sophie ; Johner, Niklaus ; Bernèche, Simon ; Kellenberger, Stephan

Proceedings of the National Academy of Sciences of the United States of America, 04 April 2017, Vol.114(14), pp.3768-3773 [Peer Reviewed Journal]

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Impact of recommended changes in labor management for prevention of the primary cesarean delivery

Thuillier, Claire ; Roy, Sophie ; Peyronnet, Violaine ; Quibel, Thibaud ; Nlandu, Aurélie ; Rozenberg, Patrick

American Journal of Obstetrics and Gynecology, March 2018, Vol.218(3), pp.341.e1-341.e9 [Peer Reviewed Journal]

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687: Changes in the cesarean rate after induction of labor after implementation of the recommendations for practice of the Joint Eunice Kennedy Shriver NICHD, the SMFM, and the ACOG workshop to prevent the first cesarean delivery

Rozenberg, Patrick ; Thuillier, Claire ; Quibel, Thibaud ; Roy, Sophie ; Nlandu, Aurélie

American Journal of Obstetrics and Gynecology, January 2016, Vol.214(1), pp.S362-S363 [Peer Reviewed Journal]

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Molecular determinants of desensitization in an ENaC/degenerin channel

Roy, Sophie ; Boiteux, Céline ; Alijevic, Omar ; Liang, Chungwen ; Bernèche, Simon ; Kellenberger, Stephan

FASEB Journal, November 2013, Vol.27(12), pp.5034-5045 [Peer Reviewed Journal]

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Le coût environnemental de la gestion documentaire

Roy, Sophie

Arbido, 01 September 2016, Issue 3, p.32

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6
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Maintenance of caspase-3 proenzyme dormancy by an intrinsic "safety catch" regulatory tripeptide

Roy, Sophie ; Bayly, Christopher ; Gareau, Yves ; Houtzager, Vicky

Proceedings of the National Academy of Sciences of the United States of America, May 22, 2001, Vol.98(11), pp.6132-6137 [Peer Reviewed Journal]

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Klimavulnerabilität von Unternehmen in der Metropolregion Oberrhein und ihre Visualisierung anhand von Wirkpfaden

Scholze, Nicolas ; Glaser, Rüdiger ; Roy, Sophie

Revue d'Allemagne et des Pays de Langue Allemande, 2018, Vol.50(2), p.325

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Multiple Outbreaks of Gastroenteritis That Were Associated with 16 Funerals and a Unique Caterer and Spanned 6 Days, 2011, Québec, Canada

Gaulin, Colette ; Nguon, Soulyvane ; Leblanc, Marie-Andree ; Ramsay, Danielle ; Roy, Sophie

Journal of Food Protection, Sep 2013, Vol.76(9), pp.1582-9 [Peer Reviewed Journal]

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9
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Antihypertensive drug development: current challenges and future opportunities

Feig, Peter U ; Roy, Sophie ; Cody, Robert J

Journal of the American Society of Hypertension : JASH, 2010, Vol.4(4), pp.163-73 [Peer Reviewed Journal]

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10
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Confinement of caspase-12 proteolytic activity to autoprocessing

Roy, Sophie ; Sharom, Jeffrey R ; Houde, Caroline ; Loisel, Thomas P ; Vaillancourt, John P ; Shao, Wei ; Saleh, Maya ; Nicholson, Donald W

Proceedings of the National Academy of Sciences of the United States of America, 18 March 2008, Vol.105(11), pp.4133-8 [Peer Reviewed Journal]

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11
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Control of the Interferon-Induced 68-Kilodalton Protein Kinase by the HIV-1 tat Gene Product

Roy, Sophie ; Katze, Michael ; Parkin, Neil ; Edery, Isaac ; Hovanessian, Ara ; Sonenberg, Nahum

Science, Mar 9, 1990, Vol.247(4947), p.1216 [Peer Reviewed Journal]

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Phosphorylation of phospholemman (FXYD1) by protein kinases A and C modulates distinct Na,K-ATPase isozymes

Bibert, Stéphanie ; Roy, Sophie ; Schaer, Danièle ; Horisberger, Jean-Daniel ; Geering, Käthi

The Journal of biological chemistry, 04 January 2008, Vol.283(1), pp.476-86 [Peer Reviewed Journal]

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Structural and functional properties of two human FXYD3 (Mat-8) isoforms

Bibert, Stéphanie ; Roy, Sophie ; Schaer, Danièle ; Felley-Bosco, Emanuela ; Geering, Käthi

The Journal of biological chemistry, 22 December 2006, Vol.281(51), pp.39142-51 [Peer Reviewed Journal]

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14
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Role of the transmembrane domain of FXYD7 in structural and functional interactions with Na,K-ATPase

Li, Ciming ; Crambert, Gilles ; Thuillard, Delphine ; Roy, Sophie ; Schaer, Danièle ; Geering, Käthi

The Journal of biological chemistry, 30 December 2005, Vol.280(52), pp.42738-43 [Peer Reviewed Journal]

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The cell adhesion molecule CEACAM1-L is a substrate of caspase-3-mediated cleavage in apoptotic mouse intestinal cells

Houde, Caroline ; Roy, Sophie ; Leung, Nelly ; Nicholson, Donald W ; Beauchemin, Nicole

The Journal of biological chemistry, 09 May 2003, Vol.278(19), pp.16929-35 [Peer Reviewed Journal]

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16
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Map2k1 and Map2k2 genes contribute to the normal development of syncytiotrophoblasts during placentation

Nadeau, Valérie ; Guillemette, Stéphanie ; Bélanger, Louis-François ; Jacob, Olivier ; Roy, Sophie ; Charron, Jean

Development (Cambridge, England), April 2009, Vol.136(8), pp.1363-74 [Peer Reviewed Journal]

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17
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Huntingtin interacting protein 1 can regulate neurogenesis in Drosophila

Moores, Justin N. ; Roy, Sophie ; Nicholson, Donald W. ; Staveley, Brian E.

European Journal of Neuroscience, August 2008, Vol.28(3), pp.599-609 [Peer Reviewed Journal]

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18
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Evolution of Na,K-ATPase beta m-subunit into a coregulator of transcription in placental mammals

Pestov, Nikolay B ; Ahmad, Nisar ; Korneenko, Tatiana V ; Zhao, Hao ; Radkov, Rossen ; Schaer, Danièle ; Roy, Sophie ; Bibert, Stéphanie ; Geering, Käthi ; Modyanov, Nikolai N

Proceedings of the National Academy of Sciences of the United States of America, 03 July 2007, Vol.104(27), pp.11215-20 [Peer Reviewed Journal]

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19
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FXYD6 is a novel regulator of Na,K-ATPase expressed in the inner ear

Delprat, Benjamin ; Schaer, Danièle ; Roy, Sophie ; Wang, Jing ; Puel, Jean-Luc ; Geering, Käthi Hamel, Christian (Editor)

Journal of Biological Chemistry, 09 March 2007, Vol.282(10), pp.7450-6 [Peer Reviewed Journal]

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20
Chronic Treatment with Mineralocorticoid Receptor Antagonists Reverses Salt-Induced Transcriptional Effects in Aorta of Dahl Salt Sensitive Rats
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Chronic Treatment with Mineralocorticoid Receptor Antagonists Reverses Salt-Induced Transcriptional Effects in Aorta of Dahl Salt Sensitive Rats

Gao, Sheng ; Li, Jun ; Zhou, Xiaoyan ; Brown, Patricia ; Puig, Oscar ; Hoek, Maarten ; Forrest, Michael ; Roy, Sophie ; Crook, Martin

Journal of Cardiac Failure, 8/2011, Vol.17(8), S, p.S33 [Peer Reviewed Journal]

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21
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Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis

Bissonauth, Vickram ; Roy, Sophie ; Gravel, Mathieu ; Guillemette, Stéphanie ; Charron, Jean

Development (Cambridge, England), September 2006, Vol.133(17), pp.3429-40 [Peer Reviewed Journal]

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22
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Cooperative action of multiple cis-acting elements is required for N-myc expression in branchial arches: specific contribution of GATA3

Potvin, Eric ; Beuret, Laurent ; Cadrin-Girard, Jean-François ; Carter, Marcelle ; Roy, Sophie ; Tremblay, Michel ; Charron, Jean

Molecular and cellular biology, November 2010, Vol.30(22), pp.5348-63 [Peer Reviewed Journal]

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23
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A combined computational and functional approach identifies new residues involved in pH-dependent gating of ASIC1a

Liechti, Luz Angélica ; Bernèche, Simon ; Bargeton, Benoîte ; Iwaszkiewicz, Justyna ; Roy, Sophie ; Michielin, Olivier ; Kellenberger, Stephan

The Journal of biological chemistry, 21 May 2010, Vol.285(21), pp.16315-29 [Peer Reviewed Journal]

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24
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Effects of the renin inhibitor MK-8141 (ACT-077825) in patients with hypertension

Jones-Burton, Charlotte ; Rubino, Joseph ; Roy, Sophie ; Mai, Yabing ; Meehan, Alan ; Bellet, Marc ; Feig, Peter

Journal of the American Society of Hypertension : JASH, 2010, Vol.4(5), pp.219-26 [Peer Reviewed Journal]

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25
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The Caspase-3 Precursor Has a Cytosolic and Mitochondrial Distribution: Implications for Apoptotic Signaling

Mancini, Marie ; Nicholson, Donald W ; Roy, Sophie ; Thornberry, Nancy A ; Peterson, Erin P ; Casciola-Rosen, Livia A ; Rosen, Antony

The Journal of Cell Biology, 1998, Vol.140(6), p.1485-1495 [Peer Reviewed Journal]

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26
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Caspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis

Mancini, Marie ; Machamer, Carolyn E ; Roy, Sophie ; Nicholson, Donald W ; Thornberry, Nancy A ; Casciola-Rosen, Livia A ; Rosen, Antony

The Journal of Cell Biology, 2000, Vol.149(3), p.603-612 [Peer Reviewed Journal]

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27
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Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

Marsden, Vanessa S ; O'Connor, Liam ; O'Reilly, Lorraine A ; Silke, John ; Metcalf, Donald ; Ekert, Paul G ; Huang, David C S ; Cecconi, Francesco ; Kuida, Keisuke ; Tomaselli, Kevin J ; Roy, Sophie ; Nicholson, Don W ; Vaux, David L ; Bouillet, Philippe ; Adams, Jerry M ; Strasser, Andreas

Nature, 10 October 2002, Vol.419(6907), pp.634-7 [Peer Reviewed Journal]

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Caspases at the Heart of the Apoptotic Cell Death Pathway
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Caspases at the Heart of the Apoptotic Cell Death Pathway

Roy, Sophie

Chemical Research in Toxicology, 10/2000, Vol.13(10), pp.961-962 [Peer Reviewed Journal]

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29
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A caspase active site probe reveals high fractional inhibition needed to block DNA fragmentation

Méthot, Nathalie ; Vaillancourt, John P ; Huang, Jingqi ; Colucci, John ; Han, Yongxin ; Ménard, Stéphane ; Zamboni, Robert ; Toulmond, Sylvie ; Nicholson, Donald W ; Roy, Sophie

The Journal of biological chemistry, 02 July 2004, Vol.279(27), pp.27905-14 [Peer Reviewed Journal]

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30
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Transcriptome profiling and network analysis of genetically hypertensive mice identifies potential pharmacological targets of hypertension

Puig, Oscar ; Wang, I-Ming ; Cheng, Ping ; Zhou, Pris ; Roy, Sophie ; Cully, Doris ; Peters, Mette ; Benita, Yair ; Thompson, John ; Cai, Tian-Quan

Physiological genomics, September 2010, Vol.42A(1), pp.24-32 [Peer Reviewed Journal]

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31
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Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment

Ayers, Kristin L ; Glicksberg, Benjamin S ; Garfield, Alastair S ; Longerich, Simonne ; White, Joseph A ; Yang, Pengwei ; Du, Lei ; Chittenden, Thomas W ; Gulcher, Jeffery R ; Roy, Sophie ; Fiedorek, Fred ; Gottesdiener, Keith ; Cohen, Sarah ; North, Kari E ; Schadt, Eric E ; Li, Shuyu D ; Chen, Rong ; Van Der Ploeg, Lex H T

The Journal of Clinical Endocrinology & Metabolism, 2018, Vol. 103(7), pp.2601-2612 [Peer Reviewed Journal]

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32
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Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats

Zhou, Xiaoyan ; Huang, Chin-Hu ; Lao, Julie ; Pocai, Alessandro ; Forrest, Gail ; Price, Olga ; Roy, Sophie ; Kelley, David E ; Sullivan, Kathleen A ; Forrest, Michael J

Cardiovascular diabetology, 07 March 2015, Vol.14, pp.29 [Peer Reviewed Journal]

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33
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Effect of inactivation of the Arg- and/or Lys-gingipain gene on selected virulence and physiological properties of Porphyromonas gingivalis

Grenier, Daniel ; Roy, Sophie ; Chandad, Fatiha ; Plamondon, Pascale ; Yoshioka, Masami ; Nakayama, Koji ; Mayrand, Denis

Infection and immunity, August 2003, Vol.71(8), pp.4742-8 [Peer Reviewed Journal]

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34
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The fatigue-induced alteration in postural control is larger in hypobaric than in normobaric hypoxia

Degache, Francis ; Serain, Émilie ; Roy, Sophie ; Faiss, Raphael ; Millet, Grégoire P

Scientific reports, 16 January 2020, Vol.10(1), pp.483 [Peer Reviewed Journal]

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35
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Mek2 is dispensable for mouse growth and development

Bélanger, Louis-François ; Roy, Sophie ; Tremblay, Michel ; Brott, Barbara ; Steff, Ann-Muriel ; Mourad, Walid ; Hugo, Patrice ; Erikson, Raymond ; Charron, Jean

Molecular and cellular biology, July 2003, Vol.23(14), pp.4778-87 [Peer Reviewed Journal]

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Discovery of a novel sub-class of ROMK channel inhibitors typified by 5-(2-(4-(2-(4-(1H-Tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-one

Tang, Haifeng ; de Jesus, Reynald K ; Walsh, Shawn P ; Zhu, Yuping ; Yan, Yan ; Priest, Birgit T ; Swensen, Andrew M ; Alonso-Galicia, Magdalena ; Felix, John P ; Brochu, Richard M ; Bailey, Timothy ; Thomas-Fowlkes, Brande ; Zhou, Xiaoyan ; Pai, Lee-Yuh ; Hampton, Caryn ; Hernandez, Melba ; Owens, Karen ; Roy, Sophie ; Kaczorowski, Gregory J ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 01 November 2013, Vol.23(21), pp.5829-5832 [Peer Reviewed Journal]

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37
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22-P002 A cooperative action of multiple cis-acting elements is required for N-myc expression in branchial arches: Specific contribution of GATA3

Charron, Jean ; Potvin, Éric ; Roy, Sophie ; Carter, Marcelle

Mechanisms of Development, August 2009, Vol.126, pp.S329-S329 [Peer Reviewed Journal]

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38