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Selective Photoaffinity Probe That Enables Assessment of Cannabinoid CB Receptor Expression and Ligand Engagement in Human Cells

Soethoudt, Marjolein ; Stolze, Sara C ; Westphal, Matthias V ; Van Stralen, Luuk ; Martella, Andrea ; Van Rooden, Eva J ; Guba, Wolfgang ; Varga, Zoltan V ; Deng, Hui ; Van Kasteren, Sander I ; Grether, Uwe ; Ijzerman, Adriaan P ; Pacher, Pal ; Carreira, Erick M ; Overkleeft, Herman S ; Ioan-Facsinay, Andreea ; Heitman, Laura H ; Van Der Stelt, Mario

Journal of the American Chemical Society, 16 May 2018, Vol.140(19), pp.6067-6075 [Peer Reviewed Journal]

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Iron‐Catalyzed Ring‐Closing C−O/C−O Metathesis of Aliphatic Ethers

Biberger, Tobias ; Makai, Szabolcs ; Lian, Zhong ; Morandi, Bill

Angewandte Chemie International Edition, 04 June 2018, Vol.57(23), pp.6940-6944 [Peer Reviewed Journal]

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New alternative to warfarin may help reduce stroke risk in patients with AF

Mitka, Mike

JAMA, 05 January 2011, Vol.305(1), pp.25-6 [Peer Reviewed Journal]

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Heterocycles via intramolecular platinum-catalyzed propargylic substitution

Liang, Qiren ; De Brabander, Jef K

Tetrahedron, 2011, Vol.67(27), pp.5046-5053 [Peer Reviewed Journal]

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Single‐Step Modular Synthesis of Unsaturated Morpholine N‐Oxides and Their Cycloaddition Reactions

Son, Jongwoo ; Kim, Ki Hwan ; Mo, Dong‐Liang ; Wink, Donald J. ; Anderson, Laura L.

Angewandte Chemie International Edition, 06 March 2017, Vol.56(11), pp.3059-3063 [Peer Reviewed Journal]

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Perioperative anaphylaxis: progress, prevention and pholcodine policy

Mcaleer, P T ; Mcnicol, L ; Rose, M A

Anaesthesia and intensive care, March 2017, Vol.45(2), pp.147-150 [Peer Reviewed Journal]

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Buparlisib-and the continued quest for the ideal cure

Worden, Francis P

The Lancet. Oncology, March 2017, Vol.18(3), pp.273-274 [Peer Reviewed Journal]

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Landiolol hydrochloride for preventing postoperative atrial fibrillation

Hajibandeh, S ; Melhado, R ; Akhtar, K ; Hajibandeh, S ; Trivedi, V ; Asaad, P

Anaesthesia, July 2018, Vol.73(7), pp.910-911 [Peer Reviewed Journal]

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Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin

Zakikhani, Mahvash ; Bazile, Miguel ; Hashemi, Sina ; Javeshghani, Shiva ; Avizonis, Daina ; St Pierre, Julie ; Pollak, Michael N

PloS one, 2012, Vol.7(11), pp.e49513 [Peer Reviewed Journal]

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Tumor selective cytotoxic action of a thiomorpholin hydroxamate inhibitor (TMI-1) in breast cancer

Mezil, Lynda ; Berruyer-Pouyet, Carole ; Cabaud, Olivier ; Josselin, Emmanuelle ; Combes, Sébastien ; Brunel, Jean-Michel ; Viens, Patrice ; Collette, Yves ; Birnbaum, Daniel ; Lopez, Marc

PloS one, 2012, Vol.7(9), pp.e43409 [Peer Reviewed Journal]

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Stereoselective Synthesis of cis ‐2,6‐Disubstituted Morpholines and 1,4‐Oxathianes by Intramolecular Reductive Etherification of 1,5‐Diketones

Gharpure, Santosh J. ; Anuradha, Dandela ; Prasad, Jonnalagadda V. K. ; Srinivasa Rao, Pidugu

European Journal of Organic Chemistry, January 2015, Vol.2015(1), pp.86-90 [Peer Reviewed Journal]

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SnAP reagents for the transformation of aldehydes into substituted thiomorpholines--an alternative to cross-coupling with saturated heterocycles

Vo, Cam-Van T ; Mikutis, Gediminas ; Bode, Jeffrey W

Angewandte Chemie (International ed. in English), 04 February 2013, Vol.52(6), pp.1705-8 [Peer Reviewed Journal]

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Rivaroxaban: a review of its use in the prevention of stroke and systemic embolism in patients with atrial fibrillation

Carter, Natalie J ; Plosker, Greg L

Drugs, May 2013, Vol.73(7), pp.715-39 [Peer Reviewed Journal]

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The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo

Lee, Zheng Wei ; Zhou, Jianbiao ; Chen, Chien-Shing ; Zhao, Yujun ; Tan, Choon-Hong ; Li, Ling ; Moore, Philip Keith ; Deng, Lih-Wen

PloS one, 2011, Vol.6(6), pp.e21077 [Peer Reviewed Journal]

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Experimental and In-Silico Investigation of Anti-Microbial Activity of 1-Chloro-2-Isocyanatoethane Derivatives of Thiomorpholine, Piperazine and Morpholine

Nwuche, Charles O ; Ujam, Oguejiofo T ; Ibezim, Akachukwu ; Ujam, Ifeoma B

PloS one, 2017, Vol.12(1), pp.e0170150 [Peer Reviewed Journal]

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Tunable Protein Stabilization In Vivo Mediated by Shield-1 in Transgenic Medaka

Froschauer, Alexander ; Kube, Lisa ; Kegler, Alexandra ; Rieger, Christiane ; Gutzeit, Herwig O

PloS one, 2015, Vol.10(7), pp.e0131252 [Peer Reviewed Journal]

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Effects of aprepitant on the pharmacokinetics of controlled-release oral oxycodone in cancer patients

Fujiwara, Yutaka ; Toyoda, Masanori ; Chayahara, Naoko ; Kiyota, Naomi ; Shimada, Takanobu ; Imamura, Yoshinori ; Mukohara, Toru ; Minami, Hironobu

PloS one, 2014, Vol.9(8), pp.e104215 [Peer Reviewed Journal]

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18
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First-in-Human Study of PF-05212384 (PKI-587), a Small-Molecule, Intravenous, Dual Inhibitor of PI3K and mTOR in Patients with Advanced Cancer

Shapiro, Geoffrey I ; Bell-Mcguinn, Katherine M ; Molina, Julian R ; Bendell, Johanna ; Spicer, James ; Kwak, Eunice L ; Pandya, Susan S ; Millham, Robert ; Borzillo, Gary ; Pierce, Kristen J ; Han, Lixin ; Houk, Brett E ; Gallo, Jorge D ; Alsina, Maria ; Braña, Irene ; Tabernero, Josep

Clinical cancer research : an official journal of the American Association for Cancer Research, 15 April 2015, Vol.21(8), pp.1888-95 [Peer Reviewed Journal]

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19
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Landiolol: a review of its use in intraoperative and postoperative tachyarrhythmias

Plosker, Greg L

Drugs, June 2013, Vol.73(9), pp.959-77 [Peer Reviewed Journal]

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20
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Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategy

Ständer, Sonja ; Siepmann, Dorothee ; Herrgott, Ilka ; Sunderkötter, Cord ; Luger, Thomas A

PloS one, 04 June 2010, Vol.5(6), pp.e10968 [Peer Reviewed Journal]

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21
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Antisense PMO found in dystrophic dog model was effective in cells from exon 7-deleted DMD patient

Saito, Takashi ; Nakamura, Akinori ; Aoki, Yoshitsugu ; Yokota, Toshifumi ; Okada, Takashi ; Osawa, Makiko ; Takeda, Shin'Ichi

PloS one, 18 August 2010, Vol.5(8), pp.e12239 [Peer Reviewed Journal]

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22
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Decreased norepinephrine transporter availability in obesity: Positron Emission Tomography imaging with (S,S)-(11)CO-methylreboxetine

Li, Chiang-Shan R ; Potenza, Marc N ; Lee, Dianne E ; Planeta, Beata ; Gallezot, Jean-Dominique ; Labaree, David ; Henry, Shannan ; Nabulsi, Nabeel ; Sinha, Rajita ; Ding, Yu-Shin ; Carson, Richard E ; Neumeister, Alexander

NeuroImage, 01 February 2014, Vol.86, pp.306-10 [Peer Reviewed Journal]

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23
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Asymmetric synthesis of (+)-(S,S)-reboxetine via a new (S)-2-(hydroxymethyl)morpholine preparation

Brenner, Eric ; Baldwin, Ronald M ; Tamagnan, Gilles

Organic letters, 03 March 2005, Vol.7(5), pp.937-9 [Peer Reviewed Journal]

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24
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Efficient, stereoselective synthesis of trans-2,5-disubstituted morpholines

Lanman, Brian A ; Myers, Andrew G

Organic letters, 18 March 2004, Vol.6(6), pp.1045-7 [Peer Reviewed Journal]

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25
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Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB

Cleghorn, Laura A T ; Ray, Peter C ; Odingo, Joshua ; Kumar, Anuradha ; Wescott, Heather ; Korkegian, Aaron ; Masquelin, Thierry ; Lopez Moure, Abraham ; Wilson, Caroline ; Davis, Susan ; Huggett, Margaret ; Turner, Penelope ; Smith, Alasdair ; Epemolu, Ola ; Zuccotto, Fabio ; Riley, Jennifer ; Scullion, Paul ; Shishikura, Yoko ; Ferguson, Liam ; Rullas

Journal of medicinal chemistry, 09 August 2018, Vol.61(15), pp.6592-6608 [Peer Reviewed Journal]

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26
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Intramolecular reductive amination strategy to the synthesis of ( R)- N-Boc-2-hydroxymethylmorpholine, N-(3,4-dichlorobenzyl)( R)-2-hydroxymethylmorpholine, and ( R)-2-benzylmorpholine

Sawant, Rajiv T ; Waghmode, Suresh B

Tetrahedron, 2010, Vol.66(11), pp.2010-2014 [Peer Reviewed Journal]

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27
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De Novo Assembly of Highly Substituted Morpholines and Piperazines

Patil, Pravin ; Madhavachary, Rudrakshula ; Kurpiewska, Katarzyna ; Kalinowska-Tłuścik, Justyna ; Dömling, Alexander

Organic letters, 03 February 2017, Vol.19(3), pp.642-645 [Peer Reviewed Journal]

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28
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Unraveling the mechanism of a reversible photoactivated molecular proton crane

Van Der Loop, Tibert H ; Ruesink, Freek ; Amirjalayer, Saeed ; Sanders, Hans J ; Buma, Wybren J ; Woutersen, S

The journal of physical chemistry. B, 13 November 2014, Vol.118(45), pp.12965-71 [Peer Reviewed Journal]

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29
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Kinetic mechanisms in morpholino-DNA surface hybridization

Liu, Yatao ; Irving, Damion ; Qiao, Wanqiong ; Ge, Dongbiao ; Levicky, Rastislav

Journal of the American Chemical Society, 03 August 2011, Vol.133(30), pp.11588-96 [Peer Reviewed Journal]

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30
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Anion Complexes with Tetrazine-Based Ligands: Formation of Strong Anion-π Interactions in Solution and in the Solid State

Savastano, Matteo ; Bazzicalupi, Carla ; Giorgi, Claudia ; García-Gallarín, Celeste ; López De La Torre, Maria Dolores ; Pichierri, Fabio ; Bianchi, Antonio ; Melguizo, Manuel

Inorganic chemistry, 15 August 2016, Vol.55(16), pp.8013-24 [Peer Reviewed Journal]

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31
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Reactive metabolite trapping screens and potential pitfalls: bioactivation of a homomorpholine and formation of an unstable thiazolidine adduct

Lenz, Eva M ; Martin, Scott ; Schmidt, Ralf ; Morin, Pierre-Emmanuel ; Smith, Robin ; Weston, Daniel J ; Bayrakdarian, Malken

Chemical research in toxicology, 16 June 2014, Vol.27(6), pp.968-80 [Peer Reviewed Journal]

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32
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Ab initio, density functional computations, FT-IR, FT-Raman and molecular geometry of 4-morpholine carbonitrile

Xavier, R John ; Raj, S Ashok

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 15 January 2013, Vol.101, pp.148-55 [Peer Reviewed Journal]

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33
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Two polymorphs of afobazole from powder diffraction data

Chernyshev, Vladimir V ; Petkune, Sanita ; Actins, Andris ; Auzins, Raimonds ; Davlyatshin, Dmitry I ; Nosyrev, Pavel V ; Velikodny, Yurii A

Acta crystallographica. Section C, Crystal structure communications, March 2013, Vol.69(Pt 3), pp.299-302 [Peer Reviewed Journal]

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34
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Use of a glycolipid inhibitor to ameliorate renal cancer in a mouse model

Chatterjee, Subroto ; Alsaeedi, Nezar ; Hou, Jennifer ; Bandaru, Veera Venkata Ratnam ; Wu, Lan ; Halushka, Marc K ; Pili, Roberto ; Ndikuyeze, Georges ; Haughey, Norman J

PloS one, 2013, Vol.8(5), pp.e63726 [Peer Reviewed Journal]

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35
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Evaluation of In Vitro Activity of the Class I PI3K Inhibitor Buparlisib (BKM120) in Pediatric Bone and Soft Tissue Sarcomas

Anderson, Jennifer L ; Park, Ann ; Akiyama, Ryan ; Tap, William D ; Denny, Christopher T ; Federman, Noah

PloS one, 2015, Vol.10(9), pp.e0133610 [Peer Reviewed Journal]

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36
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Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines

Zomerman, Walderik W ; Plasschaert, Sabine L A ; Diks, Sander H ; Lourens, Harm-Jan ; Meeuwsen-De Boer, Tiny ; Hoving, Eelco W ; Den Dunnen, Wilfred F A ; De Bont, Eveline S J M

PloS one, 2015, Vol.10(10), pp.e0141381 [Peer Reviewed Journal]

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Regulation of MMP-9 by a WIN-binding site in the monocyte-macrophage system independent from cannabinoid receptors

Tauber, Svantje ; Paulsen, Katrin ; Wolf, Susanne ; Synwoldt, Peggy ; Pahl, Andreas ; Schneider-Stock, Regine ; Ullrich, Oliver

PloS one, 2012, Vol.7(11), pp.e48272 [Peer Reviewed Journal]

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