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16 Results  for Everything (Includes Articles)

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An efficient liquid chromatography-high resolution mass spectrometry approach for the optimization of the metabolic stability of therapeutic peptides

Esposito, Simone ; Mele, Riccardo ; Ingenito, Raffaele ; Bianchi, Elisabetta ; Bonelli, Fabio ; Monteagudo, Edith ; Orsatti, Laura

Analytical and Bioanalytical Chemistry, 2017, Vol.409(10), pp.2685-2696 [Peer Reviewed Journal]

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Effect of copper salts on peptide bond formation using peptide thioesters

Ingenito, Raffaele ; Wenschuh, Holger

Organic letters, 27 November 2003, Vol.5(24), pp.4587-90 [Peer Reviewed Journal]

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Efficient loading of sulfonamide safety-catch linkers by Fmoc amino acid fluorides

Ingenito, Raffaele ; Dreznjak, Dijana ; Guffler, Stefan ; Wenschuh, Holger

Organic letters, 04 April 2002, Vol.4(7), pp.1187-8 [Peer Reviewed Journal]

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Solid Phase Synthesis of Peptide C-Terminal Thioesters by Fmoc/ t -Bu Chemistry
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Solid Phase Synthesis of Peptide C-Terminal Thioesters by Fmoc/ t -Bu Chemistry

Ingenito, Raffaele ; Bianchi, Elisabetta ; Fattori, Daniela ; Pessi, Antonello

Journal of the American Chemical Society, 12/1999, Vol.121(49), pp.11369-11374 [Peer Reviewed Journal]

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5
Engineering and Chemical Synthesis of a Transmembrane Protein:  The HCV Protease Cofactor Protein NS4A
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Engineering and Chemical Synthesis of a Transmembrane Protein:  The HCV Protease Cofactor Protein NS4A

Bianchi, Elisabetta ; Ingenito, Raffaele ; Simon, Reyna J. ; Pessi, Antonello

Journal of the American Chemical Society, 08/1999, Vol.121(33), pp.7698-7699 [Peer Reviewed Journal]

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A liquid chromatography high-resolution mass spectrometry in vitro assay to assess metabolism at the injection site of subcutaneously administered therapeutic peptides

Esposito, Simone ; de Leonibus, Maria Lucia ; Ingenito, Raffaele ; Bianchi, Elisabetta ; Orsatti, Laura ; Monteagudo, Edith

Journal of Pharmaceutical and Biomedical Analysis, 10 September 2018, Vol.159, pp.449-458 [Peer Reviewed Journal]

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ApoA-I mimetic peptides promote pre-β HDL formation in vivo causing remodeling of HDL and triglyceride accumulation at higher dose

Carballo-Jane, Ester ; Chen, Zhu ; O’neill, Edward ; Wang, Jun ; Burton, Charlotte ; Chang, Ching H ; Chen, Xun ; Eveland, Suzanne ; Frantz-Wattley, Betsy ; Gagen, Karen ; Hubbard, Brian ; Ichetovkin, Marina ; Luell, Silvi ; Meurer, Roger ; Song, Xuelei ; Strack, Alison ; Langella, Annunziata ; Cianetti, Simona ; Rech, Francesca

Bioorganic & Medicinal Chemistry, 2010, Vol.18(24), pp.8669-8678 [Peer Reviewed Journal]

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Novel potent apoA-I peptide mimetics that stimulate cholesterol efflux and pre-β particle formation in vitro

Ingenito, Raffaele ; Burton, Charlotte ; Langella, Annunziata ; Chen, Xun ; Zytko, Karolina ; Pessi, Antonello ; Wang, Jun ; Bianchi, Elisabetta

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(1), pp.236-239 [Peer Reviewed Journal]

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Discovery and SAR of novel, potent and selective hexahydrobenzonaphthyridinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)

Torrisi, Caterina ; Bisbocci, Monica ; Ingenito, Raffaele ; Ontoria, Jesus M ; Rowley, Michael ; Schultz-Fademrecht, Carsten ; Toniatti, Carlo ; Jones, Philip

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(2), pp.448-452 [Peer Reviewed Journal]

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Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1)

Bresciani, Alberto ; Missineo, Antonino ; Gallo, Mariana ; Cerretani, Mauro ; Fezzardi, Paola ; Tomei, Licia ; Cicero, Daniel Oscar ; Altamura, Sergio ; Santoprete, Alessia ; Ingenito, Raffaele ; Bianchi, Elisabetta ; Pacifici, Robert ; Dominguez, Celia ; Munoz-Sanjuan, Ignacio ; Harper, Steven ; Toledo-Sherman, Leticia ; Park, Larry C

Archives of Biochemistry and Biophysics, 01 October 2017, Vol.631, pp.31-41 [Peer Reviewed Journal]

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Optimization of the P‘-Region of Peptide Inhibitors of Hepatitis C Virus NS3/4A Protease
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Optimization of the P‘-Region of Peptide Inhibitors of Hepatitis C Virus NS3/4A Protease

Ingallinella, Paolo ; Bianchi, Elisabetta ; Ingenito, Raffaele ; Koch, Uwe ; Steinkühler, Christian ; Altamura, Sergio ; Pessi, Antonello

Biochemistry, 10/2000, Vol.39(42), pp.12898-12906 [Peer Reviewed Journal]

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12
Potent Peptide Inhibitors of Human Hepatitis C Virus NS3 Protease Are Obtained by Optimizing the Cleavage Products
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Potent Peptide Inhibitors of Human Hepatitis C Virus NS3 Protease Are Obtained by Optimizing the Cleavage Products

Ingallinella, Paolo ; Altamura, Sergio ; Bianchi, Elisabetta ; Taliani, Marina ; Ingenito, Raffaele ; Cortese, Riccardo ; De Francesco, Raffaele ; Steinkühler, Christian ; Pessi, Antonello

Biochemistry, 06/1998, Vol.37(25), pp.8906-8914 [Peer Reviewed Journal]

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13
Conformational Changes in Human Hepatitis C Virus NS3 Protease upon Binding of Product-Based Inhibitors †
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Conformational Changes in Human Hepatitis C Virus NS3 Protease upon Binding of Product-Based Inhibitors †

Bianchi, Elisabetta ; Orrù, Stefania ; Dal Piaz, Fabrizio ; Ingenito, Raffaele ; Casbarra, Annarita ; Biasiol, Gabriella ; Koch, Uwe ; Pucci, Piero ; Pessi, Antonello

Biochemistry, 10/1999, Vol.38(42), pp.13844-13852 [Peer Reviewed Journal]

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Aggregates from mutant and wild-type α-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of β-sheet and amyloid-like filaments

El-Agnaf, Omar M.A ; Jakes, Ross ; Curran, Martin D ; Middleton, Derek ; Ingenito, Raffaele ; Bianchi, Elisabetta ; Pessi, Antonello ; Neill, David ; Wallace, Andrew

FEBS Letters, 1998, Vol.440(1), pp.71-75 [Peer Reviewed Journal]

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A series of novel, potent, and selective histone deacetylase inhibitors

Jones, Philip ; Altamura, Sergio ; Chakravarty, Prasun K ; Cecchetti, Ottavia ; Francesco, Raffaele De ; Gallinari, Paola ; Ingenito, Raffaele ; Meinke, Peter T ; Petrocchi, Alessia ; Rowley, Michael ; Scarpelli, Rita ; Serafini, Sergio ; Steinkühler, Christian

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(23), pp.5948-5952 [Peer Reviewed Journal]

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Ultrasensitive quantitative measurement of huntingtin phosphorylation at residue S13

Cariulo, Cristina ; Verani, Margherita ; Martufi, Paola ; Ingenito, Raffaele ; Finotto, Marco ; Deguire, Sean M ; Lavery, Daniel J ; Toledo-Sherman, Leticia ; Lee, Ramee ; Doherty, Elizabeth M ; Vogt, Thomas F ; Dominguez, Celia ; Lashuel, Hilal A ; Petricca, Lara ; Caricasole, Andrea

Biochemical and Biophysical Research Communications, 15 January 2020, Vol.521(3), pp.549-554 [Peer Reviewed Journal]

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