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Structure of HDAC3 bound to co-repressor and inositol tetraphosphate

Watson, Peter J ; Fairall, Louise ; Santos, Guilherme M ; Schwabe, John W R

Nature, 09 January 2012, Vol.481(7381), pp.335-40 [Peer Reviewed Journal]

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Histone deacetylase activity modulates alternative splicing

Hnilicová, Jarmila ; Hozeifi, Samira ; Dušková, Eva ; Icha, Jaroslav ; Tománková, Tereza ; Staněk, David

PloS one, 02 February 2011, Vol.6(2), pp.e16727 [Peer Reviewed Journal]

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Genetic knock-down of HDAC3 does not modify disease-related phenotypes in a mouse model of Huntington's disease

Moumné, Lara ; Campbell, Ken ; Howland, David ; Ouyang, Yingbin ; Bates, Gillian P

PloS one, 2012, Vol.7(2), pp.e31080 [Peer Reviewed Journal]

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Loss of deacetylation activity of Hdac6 affects emotional behavior in mice

Fukada, Masahide ; Hanai, Atsuko ; Nakayama, Atsuo ; Suzuki, Takayoshi ; Miyata, Naoki ; Rodriguiz, Ramona M ; Wetsel, William C ; Yao, Tso-Pang ; Kawaguchi, Yoshiharu

PloS one, 2012, Vol.7(2), pp.e30924 [Peer Reviewed Journal]

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Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion

Dresselhaus, Erica ; Duerr, James M ; Vincent, Fabien ; Sylvain, Emily K ; Beyna, Mercedes ; Lanyon, Lorraine F ; Lachapelle, Erik ; Pettersson, Martin ; Bales, Kelly R ; Ramaswamy, Gayathri

PloS one, 2018, Vol.13(3), pp.e0194661 [Peer Reviewed Journal]

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The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice

Jia, Haiqun ; Wang, Ying ; Morris, Charles D ; Jacques, Vincent ; Gottesfeld, Joel M ; Rusche, James R ; Thomas, Elizabeth A

PloS one, 2016, Vol.11(3), pp.e0152498 [Peer Reviewed Journal]

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Molecular modeling study on tunnel behavior in different histone deacetylase isoforms

Thangapandian, Sundarapandian ; John, Shalini ; Lee, Yuno ; Arulalapperumal, Venkatesh ; Lee, Keun Woo

PloS one, 2012, Vol.7(11), pp.e49327 [Peer Reviewed Journal]

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HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo

Mielcarek, Michal ; Seredenina, Tamara ; Stokes, Matthew P ; Osborne, Georgina F ; Landles, Christian ; Inuabasi, Linda ; Franklin, Sophie A ; Silva, Jeffrey C ; Luthi-Carter, Ruth ; Beaumont, Vahri ; Bates, Gillian P

PloS one, 2013, Vol.8(11), pp.e80849 [Peer Reviewed Journal]

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Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

Bantscheff, Marcus ; Hopf, Carsten ; Savitski, Mikhail M ; Dittmann, Antje ; Grandi, Paola ; Michon, Anne-Marie ; Schlegl, Judith ; Abraham, Yann ; Becher, Isabelle ; Bergamini, Giovanna ; Boesche, Markus ; Delling, Manja ; Dümpelfeld, Birgit ; Eberhard, Dirk ; Huthmacher, Carola ; Mathieson, Toby ; Poeckel, Daniel ; Reader, Valérie ; Strunk, Katja ; Sweetman, Gavain ; Kruse, Ulrich ; Neubauer, Gitte ; Ramsden, Nigel G ; Drewes, Gerard

Nature biotechnology, March 2011, Vol.29(3), pp.255-65 [Peer Reviewed Journal]

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Nascent transcript sequencing visualizes transcription at nucleotide resolution

Churchman, L ; Weissman, Jonathan

Nature, Jan 20, 2011, Vol.469(7330), pp.368-73 [Peer Reviewed Journal]

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A cis-regulatory map of the Drosophila genome

Nègre, Nicolas ; Brown, Christopher ; Ma, Lijia ; Bristow, Christopher ; Miller, Steven ; Wagner, Ulrich ; Kheradpour, Pouya ; Eaton, Matthew ; Loriaux, Paul ; Sealfon, Rachel ; Li, Zirong ; Ishii, Haruhiko ; Spokony, Rebecca ; Chen, Jia ; Hwang, Lindsay ; Cheng, Chao ; Auburn, Richard ; Davis, Melissa ; Domanus

Nature, Mar 24, 2011, Vol.471(7339), pp.527-31 [Peer Reviewed Journal]

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The nexus of chromatin regulation and intermediary metabolism

Gut, Philipp ; Verdin, Eric

Nature, Oct 24, 2013, Vol.502(7472), pp.489-98 [Peer Reviewed Journal]

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13
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Histone Deacetylase Gene Expression Following Binge Alcohol Consumption in Rats and Humans

López‐Moreno, Jose Antonio ; Marcos, Miguel ; Calleja‐Conde, Javier ; Echeverry‐Alzate, Victor ; Bühler, Kora M. ; Costa‐Alba, Pilar ; Bernardo, Edgar ; Laso, Francisco‐Javier ; Rodríguez De Fonseca, Fernando ; Nadal, Roser ; Viveros, Maria Paz ; Maldonado, Rafael ; Giné, Elena

Alcoholism: Clinical and Experimental Research, October 2015, Vol.39(10), pp.1939-1950 [Peer Reviewed Journal]

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Binge Alcohol–Induced Microvesicular Liver Steatosis and Injury are Associated with Down‐Regulation of Hepatic Hdac 1, 7, 9, 10, 11 and Up‐Regulation of Hdac 3

Kirpich, Irina ; Ghare, Smita ; Zhang, Jingwen ; Gobejishvili, Leila ; Kharebava, Giorgi ; Barve, Swati Joshi ; Barker, David ; Moghe, Akshata ; Mcclain, Craig J. ; Barve, Shirish

Alcoholism: Clinical and Experimental Research, September 2012, Vol.36(9), pp.1578-1586 [Peer Reviewed Journal]

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Effects of Alcohol on Histone Deacetylase 2 (HDAC2) and the Neuroprotective Role of Trichostatin A (TSA

Agudelo, Marisela ; Gandhi, Nimisha ; Saiyed, Zainulabedin ; Pichili, Vijaya ; Thangavel, Samikkannu ; Khatavkar, Pradnya ; Yndart‐Arias, Adriana ; Nair, Madhavan

Alcoholism: Clinical and Experimental Research, August 2011, Vol.35(8), pp.1550-1556 [Peer Reviewed Journal]

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Histone Deacetylases (HDAC)‐Induced Histone Modifications in the Amygdala: A Role in Rapid Tolerance to the Anxiolytic Effects of Ethanol

Sakharkar, Amul J. ; Zhang, Huaibo ; Tang, Lei ; Shi, Guangbin ; Pandey, Subhash C.

Alcoholism: Clinical and Experimental Research, January 2012, Vol.36(1), pp.61-71 [Peer Reviewed Journal]

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17
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Increased histone deacetylase activity in peripheral blood mononuclear cells of patients with schizophrenia

Pang, Bo ; Wang, Jingyi ; Zhang, Wenbin ; Gao, Yuan ; Zhang, Jinrong ; Su, Yingying ; Kou, Changgui

Psychiatry Research, 30 November 2016, Vol.245, pp.105-107 [Peer Reviewed Journal]

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18
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Regulation of histone acetylation in the hippocampus of chronically stressed rats: a potential role of sirtuins

Ferland, C.L ; Schrader, L.A

Neuroscience, 2011, Vol.174, pp.104-114 [Peer Reviewed Journal]

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19
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The combination of irreversible EGFR TKIs and SAHA induces apoptosis and autophagy‐mediated cell death to overcome acquired resistance in EGFR T790M‐mutated lung cancer

Lee, Tae‐Gul ; Jeong, Eun‐Hui ; Kim, Seo Yun ; Kim, Hye‐Ryoun ; Kim, Cheol Hyeon

International Journal of Cancer, 01 June 2015, Vol.136(11), pp.2717-2729 [Peer Reviewed Journal]

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20
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Design, synthesis and biological evaluation of tyrosine-based hydroxamic acid analogs as novel histone deacetylases (HDACs) inhibitors

Zhang, Yingjie ; Feng, Jinhong ; Liu, Chunxi ; Fang, Hao ; Xu, Wenfang

Bioorganic & Medicinal Chemistry, 2011, Vol.19(15), pp.4437-4444 [Peer Reviewed Journal]

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21
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Design, synthesis and biological evaluation of saccharin-based N-hydroxybenzamides as histone deacetylases (HDACs) inhibitors

Fu, Huansheng ; Han, Leiqiang ; Hou, Xuben ; Dun, Yanyan ; Wang, Lei ; Gong, Xiaowei ; Fang, Hao

Bioorganic & Medicinal Chemistry, 01 September 2015, Vol.23(17), pp.5774-5781 [Peer Reviewed Journal]

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22
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HOS2 and HDA1 encode histone deacetylases with opposing roles in Candida albicans morphogenesis

Zacchi, Lucia F ; Schulz, Wade L ; Davis, Dana A

PloS one, 13 August 2010, Vol.5(8), pp.e12171 [Peer Reviewed Journal]

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23
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Histone deacetylase–mediated silencing of AMWAP expression contributes to cisplatin nephrotoxicity

Ranganathan, Punithavathi ; Hamad, Rania ; Mohamed, Riyaz ; Jayakumar, Calpurnia ; Muthusamy, Thangaraju ; Ramesh, Ganesan

Kidney International, February 2016, Vol.89(2), pp.317-326 [Peer Reviewed Journal]

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24
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Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy

Wang, Xiaojie ; Liu, Jiang ; Zhen, Junhui ; Zhang, Chun ; Wan, Qiang ; Liu, Guangyi ; Wei, Xinbing ; Zhang, Yan ; Wang, Ziying ; Han, Huirong ; Xu, Huiyan ; Bao, Chanchan ; Song, Zhenyu ; Zhang, Xiumei ; Li, Ningjun ; Yi, Fan

Kidney International, October 2014, Vol.86(4), pp.712-725 [Peer Reviewed Journal]

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25
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Profiling of Substrates for Zinc‐dependent Lysine Deacylase Enzymes: HDAC3 Exhibits Decrotonylase Activity In Vitro

Madsen, Andreas S. ; Olsen, Christian A.

Angewandte Chemie International Edition, 03 September 2012, Vol.51(36), pp.9083-9087 [Peer Reviewed Journal]

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26
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Probing Arginine Side‐Chains and Their Dynamics with Carbon‐Detected NMR Spectroscopy: Application to the 42 kDa Human Histone Deacetylase 8 at High pH

Werbeck, Nicolas D. ; Kirkpatrick, John ; Hansen, D. Flemming

Angewandte Chemie International Edition, 11 March 2013, Vol.52(11), pp.3145-3147 [Peer Reviewed Journal]

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27
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aPKC phosphorylation of HDAC6 results in increased deacetylation activity

Du, Yifeng ; Seibenhener, Michael L ; Yan, Jin ; Jiang, Jianxiong ; Wooten, Michael C

PloS one, 2015, Vol.10(4), pp.e0123191 [Peer Reviewed Journal]

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28
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Quantification of histone deacetylase isoforms in human frontal cortex, human retina, and mouse brain

Anderson, Kyle W ; Chen, Junjun ; Wang, Meiyao ; Mast, Natalia ; Pikuleva, Irina A ; Turko, Illarion V

PloS one, 2015, Vol.10(5), pp.e0126592 [Peer Reviewed Journal]

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KDAC8 with High Basal Velocity Is Not Activated by N-Acetylthioureas

Toro, Tasha B ; Pingali, Subramanya ; Nguyen, Thao P ; Garrett, Destane S ; Dodson, Kyra A ; Nichols, Kyara A ; Haynes, Rashad A ; Payton-Stewart, Florastina ; Watt, Terry J

PloS one, 2016, Vol.11(1), pp.e0146900 [Peer Reviewed Journal]

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30
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The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: Implications to protein function and drug design

Ronin, Céline ; Costa, David Mendes ; Tavares, Joana ; Faria, Joana ; Ciesielski, Fabrice ; Ciapetti, Paola ; Smith, Terry K ; Macdougall, Jane ; Cordeiro-Da-Silva, Anabela ; Pemberton, Iain K

PloS one, 2018, Vol.13(3), pp.e0193602 [Peer Reviewed Journal]

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31
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Cyclic Equibiaxial Tensile Strain Alters Gene Expression of Chondrocytes via Histone Deacetylase 4 Shuttling

Chen, Chongwei ; Wei, Xiaochun ; Lv, Zhi ; Sun, Xiaojuan ; Wang, Shaowei ; Zhang, Yang ; Jiao, Qiang ; Wang, Xiaohu ; Li, Yongping ; Wei, Lei

PloS one, 2016, Vol.11(5), pp.e0154951 [Peer Reviewed Journal]

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32
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Effects of αTAT1 and HDAC5 on axonal regeneration in adult neurons

Lin, Shen ; Sterling, Noelle A ; Junker, Ian P ; Helm, Courtney T ; Smith, George M

PloS one, 2017, Vol.12(5), pp.e0177496 [Peer Reviewed Journal]

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33
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HDAC6 regulates LPS-tolerance in astrocytes

Beurel, Eléonore

PloS one, 2011, Vol.6(10), pp.e25804 [Peer Reviewed Journal]

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34
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Anti-tumor activity of phenoxybenzamine and its inhibition of histone deacetylases

Inchiosa, Mario A

PloS one, 2018, Vol.13(6), pp.e0198514 [Peer Reviewed Journal]

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35
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HDAC inhibition: A novel therapeutic target for attenuating pulmonary hypertension by regulating Tregs

Wang, Jichun ; Saren, Gaowa ; Jiang, Hong

International Journal of Cardiology, 01 November 2015, Vol.198, pp.176-177 [Peer Reviewed Journal]

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HDAC inhibition: A novel therapeutic target for pulmonary hypertension by reducing right ventricular hypertrophy through diverse pathological mechanisms

Huang, Yi-Yuan ; Fang, Zhen-Fei ; Hu, Xin-Qu ; Zhou, Sheng-Hua

International Journal of Cardiology, 01 October 2015, Vol.196, pp.125-126 [Peer Reviewed Journal]

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37