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Potential future consideration for imaging and blood-based biomarkers for precision medicine in lung cancer

Kong, Feng-Ming Spring ; Hirsch, Fred R ; Machtay, Mitchell

Translational lung cancer research, December 2017, Vol.6(6), pp.713-715 [Peer Reviewed Journal]

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New and emerging targeted treatments in advanced non-small-cell lung cancer

Hirsch, Fred R ; Suda, Kenichi ; Wiens, Jacinta ; Bunn, Paul A

The Lancet, 03 September 2016, Vol.388(10048), pp.1012-1024 [Peer Reviewed Journal]

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"Companion diagnostics": has their time come and gone?

Hirsch, Fred R ; Bunn, Paul A ; Herbst, Roy S

Clinical cancer research : an official journal of the American Association for Cancer Research, 01 September 2014, Vol.20(17), pp.4422-4 [Peer Reviewed Journal]

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Is there clinical value to prognostic signatures in early-stage NSCLC?

Bunn, Paul A ; Hirsch, Fred R ; Aisner, Dara L

Clinical cancer research : an official journal of the American Association for Cancer Research, 01 April 2014, Vol.20(7), pp.1727-9 [Peer Reviewed Journal]

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Is the third generation EGFR TKIs the solution for making EGFR mutant NSCLC a curable disease?

Hirsch, Fred R

Translational lung cancer research, December 2014, Vol.3(6), pp.363-4 [Peer Reviewed Journal]

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6
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Squamous cell lung cancer: where do we stand and where are we going?

Hirsch, Fred R

Oncology (Williston Park, N.Y.), September 2013, Vol.27(9), pp.914-5 [Peer Reviewed Journal]

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Recent advances of biomarker research in lung cancer with special reference to new targeted therapies: Status and future challenges

Hirsch, Fred R

Lung Cancer, June 2012, Vol.77, pp.S3-S4 [Peer Reviewed Journal]

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8
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International Association for the Study of Lung Cancer (IASLC): Celebrating 40 Years with Scientific and Educational Achievements

Hirsch, Fred R

Journal of Thoracic Oncology, October 2014, Vol.9(10), pp.1424-1425 [Peer Reviewed Journal]

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The TOPICAL study should be more topical!

Hirsch, Fred R

Translational lung cancer research, February 2013, Vol.2(1), pp.62-3 [Peer Reviewed Journal]

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Programmed death ligand 1 testing: is there one best test?

Hirsch, Fred R

Clinical advances in hematology & oncology : H&O, June 2017, Vol.15(6), pp.438-440 [Peer Reviewed Journal]

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11
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Three‐arm, randomized, phase 2 study of carboplatin and paclitaxel in combination with cetuximab, cixutumumab, or both for advanced non–small cell lung cancer (NSCLC) patients who will not receive bevacizumab‐based therapy: An Eastern Cooperative Oncology Group (ECOG) study (E4508

Hanna, Nasser H. ; Dahlberg, Suzanne E. ; Kolesar, Jill M. ; Aggarwal, Charu ; Hirsch, Fred R. ; Ramalingam, Suresh S. ; Schiller, Joan H.

Cancer, 01 July 2015, Vol.121(13), pp.2253-2261 [Peer Reviewed Journal]

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12
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Lung cancer: current therapies and new targeted treatments

Hirsch, Fred R ; Scagliotti, Giorgio V ; Mulshine, James L ; Kwon, Regina ; Curran, Walter J ; Wu, Yi-Long ; Paz-Ares, Luis

The Lancet, 21 January 2017, Vol.389(10066), pp.299-311 [Peer Reviewed Journal]

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Potential effect of spliceosome inhibition in small cell lung cancer irrespective of the MYC status

Suda, Kenichi ; Rozeboom, Leslie ; Yu, Hui ; Ellison, Kim ; Rivard, Christopher J ; Mitsudomi, Tetsuya ; Hirsch, Fred R Ahmad, Aamir (editor)

PLoS ONE, 2017, Vol.12(2) [Peer Reviewed Journal]

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Design of a phase III clinical trial with prospective biomarker validation: SWOG S0819

Redman, Mary W ; Crowley, John J ; Herbst, Roy S ; Hirsch, Fred R ; Gandara, David R

Clinical cancer research : an official journal of the American Association for Cancer Research, 01 August 2012, Vol.18(15), pp.4004-12 [Peer Reviewed Journal]

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Squamous cell lung cancer: from tumor genomics to cancer therapeutics

Gandara, David R ; Hammerman, Peter S ; Sos, Martin L ; Lara, Primo N ; Hirsch, Fred R

Clinical cancer research : an official journal of the American Association for Cancer Research, 15 May 2015, Vol.21(10), pp.2236-43 [Peer Reviewed Journal]

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November - Lung Cancer Awareness Month

Hirsch, Fred R

Journal of Thoracic Oncology, November 2010, Vol.5(11), pp.1719-1720 [Peer Reviewed Journal]

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17
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The tissue is the issue: personalized medicine for non-small cell lung cancer

Hirsch, Fred R ; Wynes, Murry W ; Gandara, David R ; Bunn, Paul A

Clinical cancer research : an official journal of the American Association for Cancer Research, 15 October 2010, Vol.16(20), pp.4909-11 [Peer Reviewed Journal]

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The Bim deletion polymorphism clinical profile and its relation with tyrosine kinase inhibitor resistance in Chinese patients with non–small cell lung cancer

Zhao, Mingchuan ; Zhang, Yishi ; Cai, Weijing ; Li, Jiayu ; Zhou, Fei ; Cheng, Ningning ; Ren, Ruixin ; Zhao, Chao ; Li, Xuefei ; Ren, Shengxiang ; Zhou, Caicun ; Hirsch, Fred R.

Cancer, 01 August 2014, Vol.120(15), pp.2299-2307 [Peer Reviewed Journal]

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19
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Clinical potential of necitumumab in non-small cell lung carcinoma

Genova, Carlo ; Hirsch, Fred R

OncoTargets and therapy, 2016, Vol.9, pp.5427-37 [Peer Reviewed Journal]

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20
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PACIFIC trial: new perspectives for immunotherapy in lung cancer

Agustoni, Francesco ; Hirsch, Fred R

Translational lung cancer research, February 2018, Vol.7(Suppl 1), pp.S19-S24 [Peer Reviewed Journal]

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21
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Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1)

Kowanetz, Marcin ; Zou, Wei ; Gettinger, Scott N ; Koeppen, Hartmut ; Kockx, Mark ; Schmid, Peter ; Kadel, Edward E ; Wistuba, Ignacio ; Chaft, Jamie ; Rizvi, Naiyer A ; Spigel, David R ; Spira, Alexander ; Hirsch, Fred R ; Cohen, Victor ; Smith, Dustin ; Boyd, Zach ; Miley, Natasha ; Flynn, Susan ; Leveque, Vincent ; Shames

Proceedings of the National Academy of Sciences of the United States of America, 23 October 2018, Vol.115(43), pp.E10119-E10126 [Peer Reviewed Journal]

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22
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Patient selection criteria and the FLEX Study

Herbst, Roy S ; Hirsch, Fred R

The Lancet, 2009, Vol.373(9674), pp.1497-1498 [Peer Reviewed Journal]

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23
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From Mice to Men and Back: An Assessment of Preclinical Model Systems for the Study of Lung Cancers

Gazdar, Adi F ; Hirsch, Fred R ; Minna, John D

Journal of Thoracic Oncology, March 2016, Vol.11(3), pp.287-299 [Peer Reviewed Journal]

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24
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The mTOR Pathway in Lung Cancer and Implications for Therapy and Biomarker Analysis

Ekman, Simon ; Wynes, Murry W ; Hirsch, Fred R

Journal of Thoracic Oncology, June 2012, Vol.7(6), pp.947-953 [Peer Reviewed Journal]

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25
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A new generation of EGFR tyrosine-kinase inhibitors in NSCLC

Hirsch, Fred R ; Bunn, Paul A

Lancet Oncology, May 2012, Vol.13(5), pp.442-443 [Peer Reviewed Journal]

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26
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Correction: “From Mice to Men and Back: An Assessment of Preclinical Model Systems for the Study of Lung Cancers”

Gazdar, Adi F ; Hirsch, Fred R ; Minna, John D

Journal of Thoracic Oncology, July 2016, Vol.11(7), pp.e88-e89 [Peer Reviewed Journal]

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27
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EGFR tyrosine kinase inhibitors in squamous cell lung cancer

Hirsch, Fred R ; Herbst, Roy S ; Gandara, David R

The Lancet Oncology, August 2015, Vol.16(8), pp.872-873 [Peer Reviewed Journal]

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28
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Clinical and comparative utility of afatinib in non-small cell lung cancer

D'Arcangelo, Manolo ; Hirsch, Fred R

Biologics : targets & therapy, 2014, Vol.8, pp.183-92 [Peer Reviewed Journal]

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29
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Postprogression Prolongation of Survival in EGFR-Mutated Lung Cancer: Reconciling the ASPIRATION and IMPRESS Trials

Gandara, David R ; Redman, Mary ; Hirsch, Fred R

JAMA oncology, March 2016, Vol.2(3), pp.300-1 [Peer Reviewed Journal]

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30
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FASTACT-2: but don't act too fast

Hirsch, Fred R ; Gandara, David R

Lancet Oncology, July 2013, Vol.14(8), pp.684-685 [Peer Reviewed Journal]

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31
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Adjuvant TKIs in NSCLC: what can we learn from RADIANT?

Hirsch, Fred R ; Bunn, Paul A

Nature reviews. Clinical oncology, December 2015, Vol.12(12), pp.689-90 [Peer Reviewed Journal]

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32
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EGFR expression and the flexibility of FLEX

Hirsch, Fred R ; Herbst, Roy S

Lancet Oncology, 2012, Vol.13(1), pp.3-5 [Peer Reviewed Journal]

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33
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Programmed Death Ligand-1 Immunohistochemistry: Friend or Foe?

Kerr, Keith M ; Hirsch, Fred R

Archives of pathology & laboratory medicine, April 2016, Vol.140(4), pp.326-31 [Peer Reviewed Journal]

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34
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In Memorium

Hirsch, Fred R ; Bunn, Paul A

Journal of Thoracic Oncology, December 2011, Vol.6(12), pp.1967-1969 [Peer Reviewed Journal]

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35
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Predictive value of epidermal growth factor receptor expression for first-line chemotherapy plus cetuximab in patients with head and neck and colorectal cancer: Analysis of data from the EXTREME and CRYSTAL studies

Licitra, Lisa ; Störkel, Stephan ; Kerr, Keith M ; Van Cutsem, Eric ; Pirker, Robert ; Hirsch, Fred R ; Vermorken, Jan B ; Von Heydebreck, Anja ; Esser, Regina ; Celik, Ilhan ; Ciardiello, Fortunato

European Journal of Cancer, April 2013, Vol.49(6), pp.1161-1168 [Peer Reviewed Journal]

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36
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EGFR protein expression in non-small cell lung cancer predicts response to an EGFR tyrosine kinase inhibitor--a novel antibody for immunohistochemistry or AQUA technology

Mascaux, Celine ; Wynes, Murry W ; Kato, Yasufumi ; Tran, Cindy ; Asuncion, Bernadette Reyna ; Zhao, Jason M ; Gustavson, Mark ; Ranger-Moore, Jim ; Gaire, Fabien ; Matsubayashi, Jun ; Nagao, Toshitaka ; Yoshida, Koichi ; Ohira, Tatuso ; Ikeda, Norihiko ; Hirsch, Fred R

Clinical cancer research : an official journal of the American Association for Cancer Research, 15 December 2011, Vol.17(24), pp.7796-807 [Peer Reviewed Journal]

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37
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Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer

Glubb, Dylan M ; Cerri, Elisa ; Giese, Alexandra ; Zhang, Wei ; Mirza, Osman ; Thompson, Emma E ; Chen, Peixian ; Das, Soma ; Jassem, Jacek ; Rzyman, Witold ; Lingen, Mark W ; Salgia, Ravi ; Hirsch, Fred R ; Dziadziuszko, Rafal ; Ballmer-Hofer, Kurt ; Innocenti, Federico

Clinical cancer research : an official journal of the American Association for Cancer Research, 15 August 2011, Vol.17(16), pp.5257-67 [Peer Reviewed Journal]

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