skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Index

Results 1 - 50 of 6,145  for Everything (Includes Articles)

Results 1 2 3 4 5 next page
Result Number Material Type Add to My Shelf Action Record Details and Options
1
Drug-like properties : concepts, structure design and methods : from ADME to toxicity optimization
Material Type:
Book
Add to e-Shelf

Drug-like properties : concepts, structure design and methods : from ADME to toxicity optimization

Edward Harvel Kerns Li Di

c2008

Available at UDM McNichols Campus Library  UDM McNichols Library Stacks  (RS 420 .K47 2008 )()

View 2 versions
2
Material Type:
Journal
Add to e-Shelf

Assay and drug development technologies (Online)

2002-

Check holdings()

3
Material Type:
Journal
Add to e-Shelf

Clinical pharmacology in drug development (Online)

American College of Clinical Pharmacology.

©2012-

Online access

4
Material Type:
Journal
Add to e-Shelf

International journal of high throughput screening.

2010

Online access

5
Material Type:
Book
Add to e-Shelf

From test tube to patient : new drug development in the United States.

United States. Food and Drug Administration

2nd ed.. 1995

Online access

6
Material Type:
Journal
Add to e-Shelf

SLAS discovery : advancing life sciences R & D.

Society for Laboratory Automation and Screening, issuing body.

2017]-

Online access

7
Antiretroviral resistance in clinical practice
Material Type:
Book
Add to e-Shelf

Antiretroviral resistance in clinical practice

Geretti, Anna Maria Contributor; National Center for Biotechnology Information (U.S.)

2006

Online access

8
Material Type:
Article
Add to e-Shelf

Testing time for stem cells

Baker, Monya

Nature, 11 February 2010, Vol.463(7282), pp.719 [Peer Reviewed Journal]

Full text available

View all versions
9
Material Type:
Article
Add to e-Shelf

A proposal regarding reporting of in vitro testing results

Smith, Malcolm A ; Houghton, Peter

Clinical cancer research : an official journal of the American Association for Cancer Research, 01 June 2013, Vol.19(11), pp.2828-33 [Peer Reviewed Journal]

Full text available

10
Material Type:
Article
Add to e-Shelf

Exploiting elephants in the room

Wootton, Robert ; Demello, Andrew

Nature, Apr 8, 2010, Vol.464(7290), pp.839-40 [Peer Reviewed Journal]

Full text available

View all versions
11
Material Type:
Article
Add to e-Shelf

Development and validation of an automated high-throughput system for zebrafish in vivo screenings

Letamendia, Ainhoa ; Quevedo, Celia ; Ibarbia, Izaskun ; Virto, Juan M ; Holgado, Olaia ; Diez, Maria ; Izpisua Belmonte, Juan Carlos ; Callol-Massot, Carles

PloS one, 2012, Vol.7(5), pp.e36690 [Peer Reviewed Journal]

Full text available

View all versions
12
Material Type:
Article
Add to e-Shelf

Virtual screening by a new Clustering-based Weighted Similarity Extreme Learning Machine approach

Pasupa, Kitsuchart ; Kudisthalert, Wasu

PloS one, 2018, Vol.13(4), pp.e0195478 [Peer Reviewed Journal]

Full text available

View all versions
13
Material Type:
Article
Add to e-Shelf

Glucocorticoid-treated mice are an inappropriate positive control for long-term preclinical studies in the mdx mouse

Sali, Arpana ; Guerron, Alfredo D ; Gordish-Dressman, Heather ; Spurney, Christopher F ; Iantorno, Micaela ; Hoffman, Eric P ; Nagaraju, Kanneboyina

PloS one, 2012, Vol.7(4), pp.e34204 [Peer Reviewed Journal]

Full text available

View all versions
14
Material Type:
Article
Add to e-Shelf

Economic Evaluations of Pharmacogenetic and Pharmacogenomic Screening Tests: A Systematic Review. Second Update of the Literature

Berm, Elizabeth J J ; Looff, Margot De ; Wilffert, Bob ; Boersma, Cornelis ; Annemans, Lieven ; Vegter, Stefan ; Boven, Job F M Van ; Postma, Maarten J

PloS one, 2016, Vol.11(1), pp.e0146262 [Peer Reviewed Journal]

Full text available

View all versions
15
Material Type:
Article
Add to e-Shelf

Whole organism high content screening identifies stimulators of pancreatic beta-cell proliferation

Tsuji, Naoki ; Ninov, Nikolay ; Delawary, Mina ; Osman, Sahar ; Roh, Alex S ; Gut, Philipp ; Stainier, Didier Y R

PloS one, 2014, Vol.9(8), pp.e104112 [Peer Reviewed Journal]

Full text available

View all versions
16
Material Type:
Article
Add to e-Shelf

TCM Database@Taiwan: the world's largest traditional Chinese medicine database for drug screening in silico

Chen, Calvin Yu-Chian

PloS one, 06 January 2011, Vol.6(1), pp.e15939 [Peer Reviewed Journal]

Full text available

View all versions
17
Material Type:
Article
Add to e-Shelf

The influence of the negative-positive ratio and screening database size on the performance of machine learning-based virtual screening

Kurczab, Rafał ; Bojarski, Andrzej J

PloS one, 2017, Vol.12(4), pp.e0175410 [Peer Reviewed Journal]

Full text available

View all versions
18
Material Type:
Article
Add to e-Shelf

Elucidating the signal responses of multi-parametric surface plasmon resonance living cell sensing: a comparison between optical modeling and drug-MDCKII cell interaction measurements

Viitala, Tapani ; Granqvist, Niko ; Hallila, Susanna ; Raviña, Manuela ; Yliperttula, Marjo

PloS one, 2013, Vol.8(8), pp.e72192 [Peer Reviewed Journal]

Full text available

View all versions
19
Material Type:
Article
Add to e-Shelf

A linear combination of pharmacophore hypotheses as a new tool in search of new active compounds--an application for 5-HT1A receptor ligands

Warszycki, Dawid ; Mordalski, Stefan ; Kristiansen, Kurt ; Kafel, Rafał ; Sylte, Ingebrigt ; Chilmonczyk, Zdzisław ; Bojarski, Andrzej J

PloS one, 2013, Vol.8(12), pp.e84510 [Peer Reviewed Journal]

Full text available

View all versions
20
Material Type:
Article
Add to e-Shelf

Vinardo: A Scoring Function Based on Autodock Vina Improves Scoring, Docking, and Virtual Screening

Quiroga, Rodrigo ; Villarreal, Marcos A

PloS one, 2016, Vol.11(5), pp.e0155183 [Peer Reviewed Journal]

Full text available

View all versions
21
Material Type:
Article
Add to e-Shelf

Permeation of Therapeutic Drugs in Different Formulations across the Airway Epithelium In Vitro

Meindl, Claudia ; Stranzinger, Sandra ; Dzidic, Neira ; Salar-Behzadi, Sharareh ; Mohr, Stefan ; Zimmer, Andreas ; Fröhlich, Eleonore

PloS one, 2015, Vol.10(8), pp.e0135690 [Peer Reviewed Journal]

Full text available

View all versions
22
Material Type:
Article
Add to e-Shelf

Comparison of the safety and pharmacokinetics of ST-246® after i.v. infusion or oral administration in mice, rabbits and monkeys

Chen, Yali ; Amantana, Adams ; Tyavanagimatt, Shanthakumar R ; Zima, Daniela ; Yan, X Steven ; Kasi, Gopi ; Weeks, Morgan ; Stone, Melialani A ; Weimers, William C ; Samuel, Peter ; Tan, Ying ; Jones, Kevin F ; Lee, Daniel R ; Kickner, Shirley S ; Saville, Bradley M ; Lauzon, Martin ; Mcintyre, Alan ; Honeychurch, Kady M ; Jordan, Robert ; Hruby

PloS one, 2011, Vol.6(8), pp.e23237 [Peer Reviewed Journal]

Full text available

View all versions
23
Material Type:
Article
Add to e-Shelf

Moles of a Substance per Cell Is a Highly Informative Dosing Metric in Cell Culture

Doskey, Claire M ; Van 'T Erve, Thomas J ; Wagner, Brett A ; Buettner, Garry R

PloS one, 2015, Vol.10(7), pp.e0132572 [Peer Reviewed Journal]

Full text available

View all versions
24
Material Type:
Article
Add to e-Shelf

Computer-aided design of fragment mixtures for NMR-based screening

Arroyo, Xavier ; Goldflam, Michael ; Feliz, Miguel ; Belda, Ignasi ; Giralt, Ernest

PloS one, 2013, Vol.8(3), pp.e58571 [Peer Reviewed Journal]

Full text available

View all versions
25
Material Type:
Article
Add to e-Shelf

μOrgano: A Lego®-Like Plug & Play System for Modular Multi-Organ-Chips

Loskill, Peter ; Marcus, Sivan G ; Mathur, Anurag ; Reese, Willie Mae ; Healy, Kevin E

PloS one, 2015, Vol.10(10), pp.e0139587 [Peer Reviewed Journal]

Full text available

View all versions
26
Material Type:
Article
Add to e-Shelf

Dissemination bias in systematic reviews of animal research: a systematic review

Mueller, Katharina F ; Briel, Matthias ; Strech, Daniel ; Meerpohl, Joerg J ; Lang, Britta ; Motschall, Edith ; Gloy, Viktoria ; Lamontagne, Francois ; Bassler, Dirk

PloS one, 2014, Vol.9(12), pp.e116016 [Peer Reviewed Journal]

Full text available

View all versions
27
Material Type:
Article
Add to e-Shelf

Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease

Irwin, Ronald W ; Solinsky, Christine M ; Loya, Carlos M ; Salituro, Francesco G ; Rodgers, Kathleen E ; Bauer, Gerhard ; Rogawski, Michael A ; Brinton, Roberta Diaz

PloS one, 2015, Vol.10(6), pp.e0128313 [Peer Reviewed Journal]

Full text available

View all versions
28
Material Type:
Article
Add to e-Shelf

Microfluidics: Analog-to-digital drug screening

Wootton, Robert C R ; Demello, Andrew J

Nature, 29 February 2012, Vol.483(7387), pp.43-4 [Peer Reviewed Journal]

Full text available

View all versions
29
Material Type:
Article
Add to e-Shelf

Fragment screening for drug discovery: efficient approaches for exploring chemical space

Arnold, Eddy

Progress in biophysics and molecular biology, 2014, Vol.116(2-3), pp.81 [Peer Reviewed Journal]

Full text available

View all versions
30
Material Type:
Article
Add to e-Shelf

Genome-scale screening of drug-target associations relevant to Ki using a chemogenomics approach

Cao, Dong-Sheng ; Liang, Yi-Zeng ; Deng, Zhe ; Hu, Qian-Nan ; He, Min ; Xu, Qing-Song ; Zhou, Guang-Hua ; Zhang, Liu-Xia ; Deng, Zi-Xin ; Liu, Shao

PloS one, 2013, Vol.8(4), pp.e57680 [Peer Reviewed Journal]

Full text available

View all versions
31
Material Type:
Article
Add to e-Shelf

Formalization, annotation and analysis of diverse drug and probe screening assay datasets using the BioAssay Ontology (BAO)

Vempati, Uma D ; Przydzial, Magdalena J ; Chung, Caty ; Abeyruwan, Saminda ; Mir, Ahsan ; Sakurai, Kunie ; Visser, Ubbo ; Lemmon, Vance P ; Schürer, Stephan C

PloS one, 2012, Vol.7(11), pp.e49198 [Peer Reviewed Journal]

Full text available

View all versions
32
Material Type:
Article
Add to e-Shelf

New synthetic thrombin inhibitors: molecular design and experimental verification

Sinauridze, Elena I ; Romanov, Alexey N ; Gribkova, Irina V ; Kondakova, Olga A ; Surov, Stepan S ; Gorbatenko, Aleksander S ; Butylin, Andrey A ; Monakov, Mikhail Yu ; Bogolyubov, Alexey A ; Kuznetsov, Yuryi V ; Sulimov, Vladimir B ; Ataullakhanov, Fazoyl I

PloS one, 2011, Vol.6(5), pp.e19969 [Peer Reviewed Journal]

Full text available

View all versions
33
Material Type:
Article
Add to e-Shelf

Discovery of novel ligands for mouse olfactory receptor MOR42-3 using an in silico screening approach and in vitro validation

Bavan, Selvan ; Sherman, Benjamin ; Luetje, Charles W ; Abaffy, Tatjana

PloS one, 2014, Vol.9(3), pp.e92064 [Peer Reviewed Journal]

Full text available

View all versions
34
Material Type:
Article
Add to e-Shelf

Zebrafish as a potential model organism for drug test against hepatitis C virus

Ding, Cun-Bao ; Zhang, Jing-Pu ; Zhao, Ye ; Peng, Zong-Gen ; Song, Dan-Qing ; Jiang, Jian-Dong

PloS one, 2011, Vol.6(8), pp.e22921 [Peer Reviewed Journal]

Full text available

View all versions
35
Material Type:
Article
Add to e-Shelf

Which compound to select in lead optimization? Prospectively validated proteochemometric models guide preclinical development

Van Westen, Gerard J P ; Wegner, Jörg K ; Geluykens, Peggy ; Kwanten, Leen ; Vereycken, Inge ; Peeters, Anik ; Ijzerman, Adriaan P ; Van Vlijmen, Herman W T ; Bender, Andreas

PloS one, 2011, Vol.6(11), pp.e27518 [Peer Reviewed Journal]

Full text available

View all versions
36
Material Type:
Article
Add to e-Shelf

Spherical harmonics coefficients for ligand-based virtual screening of cyclooxygenase inhibitors

Wang, Quan ; Birod, Kerstin ; Angioni, Carlo ; Grösch, Sabine ; Geppert, Tim ; Schneider, Petra ; Rupp, Matthias ; Schneider, Gisbert

PloS one, 2011, Vol.6(7), pp.e21554 [Peer Reviewed Journal]

Full text available

View all versions
37
Material Type:
Article
Add to e-Shelf

A comparison of protein kinases inhibitor screening methods using both enzymatic activity and binding affinity determination

Rudolf, Amalie Frederikke ; Skovgaard, Tine ; Knapp, Stefan ; Jensen, Lars Juhl ; Berthelsen, Jens

PloS one, 2014, Vol.9(6), pp.e98800 [Peer Reviewed Journal]

Full text available

View all versions
38
Material Type:
Article
Add to e-Shelf

A Pipeline for Screening Small Molecules with Growth Inhibitory Activity against Burkholderia cenocepacia

Selin, Carrie ; Stietz, Maria S ; Blanchard, Jan E ; Gehrke, Sebastian S ; Bernard, Sylvain ; Hall, Dennis G ; Brown, Eric D ; Cardona, Silvia T

PloS one, 2015, Vol.10(6), pp.e0128587 [Peer Reviewed Journal]

Full text available

View all versions
39
Material Type:
Article
Add to e-Shelf

A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system

St Pierre, Cristina ; Guo, Jane ; Shin, John D ; Engstrom, Laura W ; Lee, Hyun-Hee ; Herbert, Alan ; Surdi, Laura ; Baker, James ; Salmon, Michael ; Shah, Sanjiv ; Ellis, J Michael ; Houshyar, Hani ; Crackower, Michael A ; Kleinschek, Melanie A ; Jones, Dallas C ; Hicks, Alexandra ; Zaller, Dennis M ; Alves, Stephen E ; Ramadas, Ravisankar A

PloS one, 2017, Vol.12(7), pp.e0180870 [Peer Reviewed Journal]

Full text available

View all versions