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Short communication: Evidence for a major gene by polygene interaction for milk production traits in German Holstein dairy cattle

Streit, M. ; Neugebauer, N. ; Meuwissen, T.H.E. ; Bennewitz, J.

Journal of Dairy Science, March 2011, Vol.94(3), pp.1597-1600 [Peer Reviewed Journal]

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Identification of 2-aminooxazole amides as acyl-CoA: Diacylglycerol acyltransferase 1 (DGAT1) inhibitors through scaffold hopping strategy

Kim, Hyunjin M. ; Smith, Michelle D. ; Kim, Jae-Hun ; Caplen, Mary Ann ; Chan, Tin Yau ; Mckittrick, Brian A. ; Cook, John A. ; van Heek, Margaret ; Lachowicz, Jean

Bioorganic & Medicinal Chemistry Letters, 1 December 2013, Vol.23(23), pp.6410-6414 [Peer Reviewed Journal]

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ABA‐insensitive (ABI) 4 and ABI5 synergistically regulate DGAT1 expression in Arabidopsis seedlings under stress

Kong, Yinfei ; Chen, Songbin ; Yang, Yang ; An, Chengcai

FEBS Letters, 17 September 2013, Vol.587(18), pp.3076-3082 [Peer Reviewed Journal]

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Genetic correlation between composition of bovine milk fat in winter and summer, and DGAT1 and SCD1 by season interactions

Duchemin, S. ; Bovenhuis, H. ; Stoop, W.M. ; Bouwman, A.C. ; van Arendonk, J.A.M. ; Visker, M.H.P.W.

Journal of Dairy Science, January 2013, Vol.96(1), pp.592-604 [Peer Reviewed Journal]

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Effects of the DGAT1 polymorphism on test-day milk production traits throughout lactation

Bovenhuis, H. ; Visker, M.H.P.W. ; van Valenberg, H.J.F. ; Buitenhuis, A.J. ; van Arendonk, J.A.M.

Journal of Dairy Science, September 2015, Vol.98(9), pp.6572-6582 [Peer Reviewed Journal]

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Effect of the DGAT1 K232A genotype of dairy cows on the milk metabolome and proteome

Lu, Jing ; Boeren, Sjef ; van Hooijdonk, Toon ; Vervoort, Jacques ; Hettinga, Kasper

Journal of Dairy Science, May 2015, Vol.98(5), pp.3460-3469 [Peer Reviewed Journal]

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Over-expression ofJcDGAT1fromJatropha curcasincreases seed oil levels and alters oil quality in transgenicArabidopsis thaliana

Misra, Aparna ; Khan, Kasim ; Niranjan, Abhishek ; Nath, Pravendra ; Sane, Vidhu A.

Phytochemistry, December 2013, Vol.96, pp.37-45 [Peer Reviewed Journal]

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Discovery of pyrrolopyridazines as novel DGAT1 inhibitors

Fox, Brian M. ; Iio, Kiyosei ; Li, Kexue ; Choi, Rebeka ; Inaba, Takashi ; Jackson, Simon ; Sagawa, Shoichi ; Shan, Bei ; Tanaka, Masahiro ; Yoshida, Atsuhito ; Kayser, Frank

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(20), pp.6030-6033 [Peer Reviewed Journal]

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Discovery of novel quinoline carboxylic acid series as DGAT1 inhibitors

Zhou, Gang ; Ting, Pauline C. ; Wishart, Grant ; Zorn, Nicolas ; Aslanian, Robert G. ; Lin, Mingxiang ; Smith, Michelle ; Walker, Scott S. ; Cook, John ; Van Heek, Margaret ; Lachowicz, Jean

Bioorganic & Medicinal Chemistry Letters, 1 April 2014, Vol.24(7), pp.1790-1794 [Peer Reviewed Journal]

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Discovery of diamide compounds as diacylglycerol acyltransferase 1 (DGAT1) inhibitors

Nakajima, Katsumasa ; April, Myriam ; Brewer, Jason T. ; Daniels, Thomas ; Forster, Cornelia J. ; Gilmore, Thomas A. ; Jain, Monish ; Kanter, Aaron ; Kwak, Youngshin ; Li, Jingzhou ; Mcquire, Les ; Serrano-Wu, Michael H. ; Streeper, Ryan ; Szklennik, Paul ; Thompson, James ; Wang, Bing

Bioorganic & Medicinal Chemistry Letters, 15 February 2016, Vol.26(4), pp.1245-1248 [Peer Reviewed Journal]

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Effects of DGAT1 K232A polymorphism and milking frequency on milk composition and spontaneous lipolysis in dairy cows

Vanbergue, E. ; Peyraud, J.L. ; Guinard-Flament, J. ; Charton, C. ; Barbey, S. ; Lefebvre, R. ; Gallard, Y. ; Hurtaud, C.

Journal of Dairy Science, July 2016, Vol.99(7), pp.5739-5749 [Peer Reviewed Journal]

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Influence of C16:0 and long-chain saturated fatty acids on normal variation of bovine milk fat triacylglycerol structure

Tzompa-Sosa, D.A. ; van Aken, G.A. ; van Hooijdonk, A.C.M. ; van Valenberg, H.J.F.

Journal of Dairy Science, July 2014, Vol.97(7), pp.4542-4551 [Peer Reviewed Journal]

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Milk fat triacylglycerols and their relations with milk fatty acid composition, DGAT1 K232A polymorphism, and milk production traits

Tzompa-Sosa, D.A. ; van Valenberg, H.J.F. ; van Aken, G.A. ; Bovenhuis, H.

Journal of Dairy Science, May 2016, Vol.99(5), pp.3624-3631 [Peer Reviewed Journal]

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Transcript analysis at DGAT1 reveals different mRNA profiles in river buffaloes with extreme phenotypes for milk fat

Gu, M. ; Cosenza, G. ; Nicolae, I. ; Bota, A. ; Guo, Y. ; Di Stasio, L. ; Pauciullo, A.

Journal of Dairy Science, October 2017, Vol.100(10), pp.8265-8276 [Peer Reviewed Journal]

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Linseed oil and DGAT1 K232A polymorphism: Effects on methane emission, energy and nitrogen metabolism, lactation performance, ruminal fermentation, and rumen microbial composition of Holstein-Friesian cows

van Gastelen, S. ; Visker, M.H.P.W. ; Edwards, J.E. ; Antunes-Fernandes, E.C. ; Hettinga, K.A. ; Alferink, S.J.J. ; Hendriks, W.H. ; Bovenhuis, H. ; Smidt, H. ; Dijkstra, J.

Journal of Dairy Science, November 2017, Vol.100(11), pp.8939-8957 [Peer Reviewed Journal]

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Association of DGAT1 genotype, fatty acid composition, and concentration of copper in milk with spontaneous oxidized flavor

Juhlin, J. ; Fikse, W.F. ; Pickova, J. ; Lundén, A.

Journal of Dairy Science, August 2012, Vol.95(8), pp.4610-4617 [Peer Reviewed Journal]

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17
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Lactation curve models for estimating gene effects over a timeline

Strucken, E.M. ; de Koning, D.J. ; Rahmatalla, S.A. ; Brockmann, G.A.

Journal of Dairy Science, January 2011, Vol.94(1), pp.442-449 [Peer Reviewed Journal]

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A novel coenzyme A:diacylglycerol acyltransferase 1 inhibitor stimulates lipid metabolism in muscle and lowers weight in animal models of obesity

Yamamoto, Toshihiro ; Yamaguchi, Hiroshi ; Miki, Hiroshi ; Kitamura, Shuji ; Nakada, Yoshihisa ; Aicher, Thomas D. ; Pratt, Scott A. ; Kato, Koki

European Journal of Pharmacology, 2011, Vol.650(2), pp.663-672 [Peer Reviewed Journal]

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Short communication: The effect of linseed oil and DGAT1 K232A polymorphism on the methane emission prediction potential of milk fatty acids

van Gastelen, S. ; Antunes-Fernandes, E.C. ; Hettinga, K.A. ; Dijkstra, J.

Journal of Dairy Science, June 2018, Vol.101(6), pp.5599-5604 [Peer Reviewed Journal]

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20
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Effects of the diacylglycerol o-acyltransferase 1 (DGAT1) K232A polymorphism on fatty acid, protein, and mineral composition of dairy cattle milk

Bovenhuis, H. ; Visker, M.H.P.W. ; Poulsen, N.A. ; Sehested, J. ; van Valenberg, H.J.F. ; van Arendonk, J.A.M. ; Larsen, L.B. ; Buitenhuis, A.J.

Journal of Dairy Science, April 2016, Vol.99(4), pp.3113-3123 [Peer Reviewed Journal]

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21
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Pleiotropic effects of polymorphism of the gene diacylglycerol-O-transferase 1 (DGAT1) in the mammary gland tissue of dairy cows

Mach, N. ; Blum, Y. ; Bannink, A. ; Causeur, D. ; Houee-Bigot, M. ; Lagarrigue, S. ; Smits, M.A.

Journal of Dairy Science, September 2012, Vol.95(9), pp.4989-5000 [Peer Reviewed Journal]

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22
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Type 1 diacylglycerol acyltransferases of Brassica napus preferentially incorporate oleic acid into triacylglycerol

Aznar - Moreno, Jose ; Denolf, Peter ; Van Audenhove, Katrien ; De Bodt, Stefanie ; Engelen, Steven ; Fahy, Deirdre ; Wallis, James G ; Browse, John

Journal Of Experimental Botany, 2015, Vol. 66(20), pp.6497-6506 [Peer Reviewed Journal]

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23
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Intestinally Targeted Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitors Robustly Suppress Postprandial Triglycerides

Serrano-Wu, Michael H ; Coppola, Gary M ; Gong, Yongjin ; Neubert, Alan D ; Chatelain, Ricardo ; Clairmont, Kevin B ; Commerford, Renee ; Cosker, Theresa ; Daniels, Thomas ; Hou, Ying ; Jain, Monish ; Juedes, Marlene ; Li, Lisha ; Mullarkey, Tara ; Rocheford, Erik ; Sung, Moo Je ; Tyler, Andrew ; Yang, Qing ; Yoon, Taeyoung ; Hubbard, Brian K

ACS medicinal chemistry letters, 10 May 2012, Vol.3(5), pp.411-5 [Peer Reviewed Journal]

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24
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Design and synthesis of potent carboxylic acid DGAT1 inhibitors with high cell permeability

Bali, Ustav ; Barba, Oscar ; Dawson, Graham ; Gattrell, William T. ; Horswill, James G. ; Pan, David A. ; Procter, Martin J. ; Rasamison, Chrystelle M. ; Sambrook Smith, Colin P. ; Taylor-Warne, Amanda ; Wong-Kai-In, Philippe

Bioorganic & Medicinal Chemistry Letters, 15 January 2012, Vol.22(2), pp.824-828 [Peer Reviewed Journal]

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25
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Characterization of monoacylglycerol acyltransferase 2 inhibitors by a novel probe in binding assays

Ma, Zhengping ; Chao, Hannguang J. ; Turdi, Huji ; Hangeland, Jon J. ; Friends, Todd ; Kopcho, Lisa M. ; Lawrence, R. Michael ; Cheng, Dong

Analytical Biochemistry, 15 May 2016, Vol.501, pp.48-55 [Peer Reviewed Journal]

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26
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Discovery of dimethyl pent-4-ynoic acid derivatives, as potent and orally bioavailable DGAT1 inhibitors that suppress body weight in diet-induced mouse obesity model

Yu, Tao ; Wu, Chengde ; Shih, Nengyang ; Li, Qi ; Chan, Chichung ; Pan, He ; Yao, Dan ; Pan, Yan ; Liang, Wei ; Shen, Liang ; Zhao, Hui ; Li, Jian ; Chen, Shuhui

Bioorganic & Medicinal Chemistry Letters, 1 June 2018, Vol.28(10), pp.1686-1692 [Peer Reviewed Journal]

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27
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Diacylglycerol acyltransferase 1, stearoyl-CoA desaturase 1, and sterol regulatory element binding protein 1 gene polymorphisms and milk fatty acid composition in Italian Brown cattle

Conte, G. ; Mele, M. ; Chessa, S. ; Castiglioni, B. ; Serra, A. ; Pagnacco, G. ; Secchiari, P.

Journal of Dairy Science, February 2010, Vol.93(2), pp.753-763 [Peer Reviewed Journal]

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28
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DS-7250, a Diacylglycerol Acyltransferase 1 Inhibitor, Enhances Hepatic Steatosis in Zucker Fatty Rats via Upregulation of Fatty Acid Synthesis

Yasuno, Kyohei ; Kumagai, Kazuyoshi ; Iguchi, Takuma ; Tsuchiya, Yoshimi ; Kai, Kiyonori ; Mori, Kazuhiko

Toxicologic Pathology, April 2018, Vol.46(3), pp.302-311 [Peer Reviewed Journal]

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29
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Molecular and genetic characterization of DGAT1 gene in Sudanese dairy cattle Kenana and Butana

Ali, S

Journal of Animal Science, Sep 2016, Vol.94, pp.102-103 [Peer Reviewed Journal]

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Genomic analysis of lactation persistency in four breeds of dairy cattle

Cole, J ; Null, D ; Gaddis, K

Journal of Animal Science, Oct 2016, Vol.94, p.160 [Peer Reviewed Journal]

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31
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Productive performance of the dairy cattle Girolando breed mediated by the fat-related genes DGAT1 and LEP and their polymorphisms

Cardoso, S.R. ; Queiroz, L.B. ; Goulart, V. Alonso ; Mourão, G.B. ; Benedetti, E. ; Goulart, L.R.

Research in Veterinary Science, 2011, Vol.91(3), pp.e107-e112 [Peer Reviewed Journal]

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32
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Effects of SCD1- and DGAT1-genes on production traits of Chinese Holstein cows located in the Delta Region of Yangtze River

Mao, Y.J. ; Chen, R.J. ; Chang, L.L. ; Chen, Y. ; Ji, D.J. ; Wu, X.X. ; Shi, X.K. ; Wu, H.T. ; Zhang, M.R. ; Yang, Z.P. ; König, S. ; Yang, L.G.

Livestock Science, May 2012, Vol.145(1-3), pp.280-286 [Peer Reviewed Journal]

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33
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Palmitic Acid and DGAT1 Deficiency Enhance Osteoclastogenesis, while Oleic Acid‐Induced Triglyceride Formation Prevents It

Drosatos‐Tampakaki, Zoi ; Drosatos, Konstantinos ; Siegelin, Yasemin ; Gong, Shan ; Khan, Salmiyeh ; Van Dyke, Thomas ; Goldberg, Ira J ; Schulze, P Christian ; Schulze‐Späte, Ulrike

Journal of Bone and Mineral Research, May 2014, Vol.29(5), pp.1183-1195 [Peer Reviewed Journal]

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34
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Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice

Streeper, Ryan S ; Grueter, Carrie A ; Salomonis, Nathan ; Cases, Sylvaine ; Levin, Malin C ; Koliwad, Suneil K ; Zhou, Ping ; Hirschey, Matthew D ; Verdin, Eric ; Farese, Robert V

Aging (Albany NY), 2012, Vol.4(1), p.13-27 [Peer Reviewed Journal]

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35
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LQTA-R: A new 3D-QSAR methodology applied to a set of DGAT1 inhibitors

Patil, Rajesh B. ; Barbosa, Euzebio G. ; Sangshetti, Jaiprakash N. ; Sawant, Sanjay D. ; Zambre, Vishal P.

Computational Biology and Chemistry, June 2018, Vol.74, pp.123-131 [Peer Reviewed Journal]

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