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Lengthening the intersubunit linker of procaspase 3 leads to constitutive activation

Mackenzie, Sarah H ; Schipper, Joshua L ; England, Erika J ; Thomas, Melvin E ; Blackburn, Kevin ; Swartz, Paul ; Clark, A Clay

Biochemistry, 10 September 2013, Vol.52(36), pp.6219-31 [Peer Reviewed Journal]

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Modifying caspase-3 activity by altering allosteric networks

Cade, Christine ; Swartz, Paul ; Mackenzie, Sarah H ; Clark, A Clay

Biochemistry, 09 December 2014, Vol.53(48), pp.7582-95 [Peer Reviewed Journal]

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Slow folding and assembly of a procaspase-3 interface variant

Mackenzie, Sarah H ; Clark, A Clay

Biochemistry, 21 May 2013, Vol.52(20), pp.3415-27 [Peer Reviewed Journal]

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Cell death starts early after subarachnoid hemorrhage

Friedrich, Victor ; Flores, Rowena ; Sehba, Fatima A

Neuroscience Letters, 14 March 2012, Vol.512(1), pp.6-11 [Peer Reviewed Journal]

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The X‐linked inhibitor of apoptosis regulates long‐term depression and learning rate

Gibon, Julien ; Unsain, Nicolas ; Gamache, Karine ; Thomas, Rhalena A. ; De Leon, Andres ; Johnstone, Aaron ; Nader, Karim ; Séguéla, Philippe ; Barker, Philip A.

FASEB Journal, September 2016, Vol.30(9), pp.3083-3090 [Peer Reviewed Journal]

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p14 ARF induces apoptosis via an entirely caspase‐3‐dependent mitochondrial amplification loop

Milojkovic, Ana ; Hemmati, Philipp G. ; Müer, Annika ; Overkamp, Tim ; Chumduri, Cindrilla ; Jänicke, Reiner U. ; Gillissen, Bernd ; Daniel, Peter T.

International Journal of Cancer, 01 December 2013, Vol.133(11), pp.2551-2562 [Peer Reviewed Journal]

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Preclinical Studies Identify Non-Apoptotic Low-Level Caspase-3 as Therapeutic Target in Pemphigus Vulgaris

Luyet, Camille ; Schulze, Katja ; Sayar, Beyza ; Howald, Denise ; Müller, Eliane ; Galichet, Arnaud

PLoS One, Mar 2015, Vol.10(3), p.e0119809 [Peer Reviewed Journal]

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Fluorogenic Substrates for In Situ Monitoring of Caspase-3 Activity in Live Cells

Pérez-López, Ana ; Marsden, Emma ; Lilienkampf, Annamaria ; Bradley, Mark

PLoS One, May 2016, Vol.11(5), p.e0153209 [Peer Reviewed Journal]

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Modulation of apoptotic response by LAR family phosphatases–cIAP1 signaling during urinary tract morphogenesis

Stewart, Katherine ; Tang, You ; Shafer, Maxwell ; Graham-Paquin, Adda-Lee ; Bouchard, Maxime

Proceedings of the National Academy of Sciences of the United States of America, Oct 24, 2017, Vol.114(43), p.E9016 [Peer Reviewed Journal]

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Consequences of cesarean delivery for neural development

Swift-Gallant, Ashlyn ; Jordan, Cynthia ; Breedlove, S

Proceedings of the National Academy of Sciences of the United States of America, Nov 13, 2018, Vol.115(46), p.11664 [Peer Reviewed Journal]

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A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3

Murthy, Aditya ; Li, Yun ; Peng, Ivan ; Reichelt, Mike ; Katakam, Anand Kumar ; Noubade, Rajkumar ; Roose-Girma, Merone ; Devoss, Jason ; Diehl, Lauri ; Graham, Robert R ; Van Lookeren Campagne, Menno

Nature, 27 February 2014, Vol.506(7489), pp.456-62 [Peer Reviewed Journal]

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Atorvastatin attenuates cognitive deficits through Akt1/caspase-3 signaling pathway in ischemic stroke

Yang, Jie ; Pan, Ying ; Li, Xuejing ; Wang, Xianying

Brain Research, 10 December 2015, Vol.1629, pp.231-239 [Peer Reviewed Journal]

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Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

Wang, Yupeng ; Gao, Wenqing ; Shi, Xuyan ; Ding, Jingjin ; Liu, Wang ; He, Huabin ; Wang, Kun ; Shao, Feng

Nature, 06 July 2017, Vol.547(7661), pp.99-103 [Peer Reviewed Journal]

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Positron Emission Tomography Imaging of Drug‐Induced Tumor Apoptosis with a Caspase‐Triggered Nanoaggregation Probe

Shen, Bin ; Jeon, Jongho ; Palner, Mikael ; Ye, Deju ; Shuhendler, Adam ; Chin, Frederick T. ; Rao, Jianghong

Angewandte Chemie International Edition, 27 September 2013, Vol.52(40), pp.10511-10514 [Peer Reviewed Journal]

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Metformin protects the brain against ischemia/reperfusion injury through PI3K/Akt1/JNK3 signaling pathways in rats

Ge, Xu-Hua ; Zhu, Guo-Ji ; Geng, De-Qin ; Zhang, Han-Zhi ; He, Juan-Mei ; Guo, Ai-Zhen ; Ma, Lin-Lin ; Yu, De-Hua

Physiology & Behavior, 01 March 2017, Vol.170, pp.115-123 [Peer Reviewed Journal]

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Caspase 3 Targeted Cargo Delivery in Apoptotic Cells Using Capped Mesoporous Silica Nanoparticles

De La Torre, Cristina ; Mondragón, Laura ; Coll, Carmen ; García‐Fernández, Alba ; Sancenón, Félix ; Martínez‐Máñez, Ramón ; Amorós, Pedro ; Pérez‐Payá, Enrique ; Orzáez, Mar

Chemistry – A European Journal, 26 October 2015, Vol.21(44), pp.15506-15510 [Peer Reviewed Journal]

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The effect of active caspase-3 on degradation of chicken myofibrillar proteins and structure of myofibrils

Huang, Ming ; Huang, Feng ; Xue, Mei ; Xu, Xinglian ; Zhou, Guanghong

Food Chemistry, 01 September 2011, Vol.128(1), pp.22-27 [Peer Reviewed Journal]

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Retinoic acid receptor and CNGA2 channel signaling are part of a regulatory feedback loop controlling axonal convergence and survival of olfactory sensory neurons

Ztokatli, Hande Ö ; Hörnberg, Maria ; Berghard, Anna ; Bohm, Staffan

FASEB Journal, February 2012, Vol.26(2), pp.617-627 [Peer Reviewed Journal]

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19
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Down‐regulation of MIF by NFκB under hypoxia accelerated neuronal loss during stroke

Zhang, Si ; Zis, Odysseus ; Ly, Philip T. T. ; Wu, Yili ; Zhang, Shuting ; Zhang, Mingming ; Cai, Fang ; Bucala, Richard ; Shyu, Woei‐Cherng ; Song, Weihong

FASEB Journal, October 2014, Vol.28(10), pp.4394-4407 [Peer Reviewed Journal]

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20
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Effects of energy deficit, dietary protein, and feeding on intracellular regulators of skeletal muscle proteolysis

Carbone, John W. ; Margolis, Lee M. ; Mcclung, James P. ; Cao, Jay J. ; Murphy, Nancy E. ; Sauter, Edward R. ; Combs, Gerald F. ; Young, Andrew J. ; Pasiakos, Stefan M.

FASEB Journal, November 2013, Vol.27(12), pp.5104-5111 [Peer Reviewed Journal]

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21
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Di-n-butyl phthalate, butylbenzyl phthalate and their metabolites induce haemolysis and eryptosis in human erythrocytes

Sicińska, Paulina

Chemosphere, July 2018, Vol.203, pp.44-53 [Peer Reviewed Journal]

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22
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Nerve regeneration in chitosan conduits and in autologous nerve grafts in healthy and in type 2 diabetic Goto–Kakizaki rats

Stenberg, Lena ; Kodama, Akira ; Lindwall‐Blom, Charlotta ; Dahlin, Lars B.

European Journal of Neuroscience, February 2016, Vol.43(3), pp.463-473 [Peer Reviewed Journal]

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23
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Engineering a light-activated caspase-3 for precise ablation of neurons in vivo

Smart, Ashley D ; Pache, Roland A ; Thomsen, Nathan D ; Kortemme, Tanja ; Davis, Graeme W ; Wells, James A

Proceedings of the National Academy of Sciences of the United States of America, 26 September 2017, Vol.114(39), pp.E8174-E8183 [Peer Reviewed Journal]

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24
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Staphylococcus aureus targets the purine salvage pathway to kill phagocytes

Winstel, Volker ; Missiakas, Dominique ; Schneewind, Olaf

Proceedings of the National Academy of Sciences of the United States of America, Jun 26, 2018, Vol.115(26), p.6846 [Peer Reviewed Journal]

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25
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Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria

Guerra-Castellano, Alejandra ; Díaz-Quintana, Antonio ; Pérez-Mejías, Gonzalo ; Elena-Real, Carlos ; González-Arzola, Katiuska ; García-Mauriño, Sofía ; De La Rosa, Miguel ; Díaz-Moreno, Irene

Proceedings of the National Academy of Sciences of the United States of America, Jul 31, 2018, Vol.115(31), p.7955 [Peer Reviewed Journal]

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26
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Protein kinase C delta phosphorylates ecdysone receptor B1 to promote gene expression and apoptosis under 20-hydroxyecdysone regulation

Chen, Cai-Hua ; Pan, Jing ; Di, Yu-Qin ; Liu, Wen ; Hou, Li ; Wang, Jin-Xing ; Zhao, Xiao-Fan

Proceedings of the National Academy of Sciences of the United States of America, Aug 22, 2017, Vol.114(34), p.E7121 [Peer Reviewed Journal]

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27
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Discovery of a small-molecule inhibitor of specific serine residue BAD phosphorylation

Pandey, Vijay ; Wang, Baocheng ; Mohan, Chakrabhavi ; Raquib, Ainiah ; Rangappa, Shobith ; Srinivasa, Venkatachalaiah ; Fuchs, Julian ; Girish, Kesturu ; Zhu, Tao ; Bender, Andreas ; Ma, Lan ; Yin, Zhinan ; Basappa, Kanchugarakoppal ; Rangappa, Peter ; Lobie, Peter

Proceedings of the National Academy of Sciences of the United States of America, Oct 30, 2018, Vol.115(44), p.E10505 [Peer Reviewed Journal]

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28
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Structural insights into the calcium-dependent interaction between calbindin-D28K and caspase-3

Bobay, Benjamin G ; Stewart, Amanda L ; Tucker, Ashley T ; Thompson, Richele J ; Varney, Kristen M ; Cavanagh, John

FEBS Letters, 19 October 2012, Vol.586(20), pp.3582-3589 [Peer Reviewed Journal]

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29
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Chemiluminescent detection of cell apoptosis enzyme by gold nanoparticle-based resonance energy transfer assay

Huang, Xiangyi ; Liang, Yiran ; Ruan, Lingao ; Ren, Jicun

Analytical and Bioanalytical Chemistry, 2014, Vol.406(23), pp.5677-5684 [Peer Reviewed Journal]

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30
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Caspase‐3 regulates the migration, invasion and metastasis of colon cancer cells

Zhou, Min ; Liu, Xinjian ; Li, Zonghai ; Huang, Qian ; Li, Fang ; Li, Chuan‐Yuan

International Journal of Cancer, 15 August 2018, Vol.143(4), pp.921-930 [Peer Reviewed Journal]

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31
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Structural basis for alpha fetoprotein‐mediated inhibition of caspase‐3 activity in hepatocellular carcinoma cells

Lin, Bo ; Zhu, Mingyue ; Wang, Wenting ; Li, Wei ; Dong, Xu ; Chen, Yi ; Lu, Yan ; Guo, Junli ; Li, Mengsen

International Journal of Cancer, 01 October 2017, Vol.141(7), pp.1413-1421 [Peer Reviewed Journal]

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32
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TAMRA- and Cy5-labeled probe for efficient kinetic characterization of caspase-3

Lee, Gwan-Ho ; Lee, Eun Jeong ; Hah, Sang Soo

Analytical Biochemistry, 01 February 2014, Vol.446, pp.22-24 [Peer Reviewed Journal]

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Molecular features of neural stem cells enable their enrichment using pharmacological inhibitors of survival‐promoting kinases

Brazel, Christine Y. ; Alaythan, Abdulaziz A. ; Felling, Ryan J. ; Calderon, Frances ; Levison, Steven W.

Journal of Neurochemistry, February 2014, Vol.128(3), pp.376-390 [Peer Reviewed Journal]

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Calpastatin inhibits motor neuron death and increases survival of hSOD1G93A mice

Rao, Mala V. ; Campbell, Jabbar ; Palaniappan, Arti ; Kumar, Asok ; Nixon, Ralph A.

Journal of Neurochemistry, April 2016, Vol.137(2), pp.253-265 [Peer Reviewed Journal]

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35
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Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death

Shlezinger, Neta ; Irmer, Henriette ; Dhingra, Sourabh ; Beattie, Sarah ; Cramer, Robert ; Braus, Gerhard ; Amir, Sharon ; Hohl, Tobias

Science, Sep 8, 2017, Vol.357(6355), pp.1037-1041 [Peer Reviewed Journal]

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Increased placental XIAP and caspase 3 is associated with increased placental apoptosis in a baboon model of maternal nutrient reduction

Arroyo, Juan A ; Li, Cun ; Schlabritz-Loutsevitch, Natalia ; Mcdonald, Tom ; Nathanielsz, Peter ; Galan, Henry L

American Journal of Obstetrics and Gynecology, 2010, Vol.203(4), pp.364.e13-364.e18 [Peer Reviewed Journal]

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