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New approaches for the treatment of lupus nephritis in the 21st century: from the laboratory to the clinic

Ripoll, Èlia ; Merino, Ana ; Grinyó, Josep ; Torras, Juan

Immunotherapy, Vol.5(10), pp.1089-101 [Peer Reviewed Journal]

Oct 2013

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A plant-produced Pfs25 VLP malaria vaccine candidate induces persistent transmission blocking antibodies against Plasmodium falciparum in immunized mice

Jones, R Mark ; Chichester, Jessica A ; Mett, Vadim ; Jaje, Jennifer ; Tottey, Stephen ; Manceva, Slobodanka ; Casta, Louis J ; Gibbs, Sandra K ; Musiychuk, Konstantin ; Shamloul, Moneim ; Norikane, Joey ; Mett, Valentina ; Streatfield, Stephen J ; Van De Vegte-Bolmer, Marga ; Roeffen, Will ; Sauerwein, Robert W ; Yusibov, Vidadi

PloS one, 2013, Vol.8(11), pp.e79538 [Peer Reviewed Journal]

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Influence of anti-Nogo-A antibody treatment on the reorganization of callosal connectivity of the premotor cortical areas following unilateral lesion of primary motor cortex (M1) in adult macaque monkeys

Hamadjida, Adjia ; Wyss, Alexander F ; Mir, Anis ; Schwab, Martin E ; Belhaj-Saif, Abderaouf ; Rouiller, Eric M

Experimental brain research, November 2012, Vol.223(3), pp.321-40 [Peer Reviewed Journal]

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Refinement of immunizing antigens to produce functional blocking antibodies against the AniA nitrite reductase of Neisseria gonorrhoeae

Shewell, Lucy K ; Jen, Freda E-C ; Jennings, Michael P

PloS one, 2017, Vol.12(8), pp.e0182555 [Peer Reviewed Journal]

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In vitro and in vivo antagonism of a G protein-coupled receptor (S1P3) with a novel blocking monoclonal antibody

Harris, Greg L ; Creason, Michael B ; Brulte, Greg B ; Herr, Deron R

PloS one, 2012, Vol.7(4), pp.e35129 [Peer Reviewed Journal]

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Selective Blockade of Interferon-α and -β Reveals Their Non-Redundant Functions in a Mouse Model of West Nile Virus Infection

Sheehan, Kathleen C F ; Lazear, Helen M ; Diamond, Michael S ; Schreiber, Robert D

PloS one, 2015, Vol.10(5), pp.e0128636 [Peer Reviewed Journal]

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Targeting natural killer cell reactivity by employing antibody to NKp46: implications for type 1 diabetes

Yossef, Rami ; Gur, Chamutal ; Shemesh, Avishai ; Guttman, Ofer ; Hadad, Uzi ; Nedvetzki, Shlomo ; Miletić, Antonija ; Nalbandyan, Karen ; Cerwenka, Adelheid ; Jonjic, Stipan ; Mandelboim, Ofer ; Porgador, Angel

PloS one, 2015, Vol.10(2), pp.e0118936 [Peer Reviewed Journal]

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A genetically humanized mouse model for hepatitis C virus infection

Dorner, Marcus ; Horwitz, Joshua ; Robbins, Justin ; Barry, Walter ; Feng, Qian ; Mu, Kathy ; Jones, Christopher ; Schoggins, John ; Catanese, Maria ; Burton, Dennis ; Law, Mansun ; Rice, Charles ; Ploss, Alexander

Nature, Jun 9, 2011, pp.208-11 [Peer Reviewed Journal]

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Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals

Carrillo, Jorge ; Molinos-Albert, Luis Manuel ; Rodríguez De La Concepción, Maria Luisa ; Marfil, Silvia ; García, Elisabet ; Derking, Ronald ; Sanders, Rogier W ; Clotet, Bonaventura ; Blanco, Julià

PloS one, 2015, Vol.10(3), pp.e0120648 [Peer Reviewed Journal]

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New blocking antibodies impede adhesion, migration and survival of ovarian cancer cells, highlighting MFGE8 as a potential therapeutic target of human ovarian carcinoma

Tibaldi, Lorenzo ; Leyman, Shirley ; Nicolas, André ; Notebaert, Sofie ; Dewulf, Melissa ; Ngo, Thu Hoa ; Zuany-Amorim, Claudia ; Amzallag, Nathalie ; Bernard-Pierrot, Isabelle ; Sastre-Garau, Xavier ; Théry, Clotilde

PloS one, 2013, Vol.8(8), pp.e72708 [Peer Reviewed Journal]

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Controlled local delivery of CTLA-4 blocking antibody induces CD8+ T-cell-dependent tumor eradication and decreases risk of toxic side effects

Fransen, Marieke F ; Van Der Sluis, Tetje C ; Ossendorp, Ferry ; Arens, Ramon ; Melief, Cornelis J M

Clinical cancer research : an official journal of the American Association for Cancer Research, 01 October 2013, Vol.19(19), pp.5381-9 [Peer Reviewed Journal]

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Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma

Nandhu, Mohan S ; Behera, Prajna ; Bhaskaran, Vivek ; Longo, Sharon L ; Barrera-Arenas, Lina M ; Sengupta, Sadhak ; Rodriguez-Gil, Diego J ; Chiocca, E Antonio ; Viapiano, Mariano S

Clinical cancer research : an official journal of the American Association for Cancer Research, 15 February 2018, Vol.24(4), pp.821-833 [Peer Reviewed Journal]

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Intratumoral anti-CTLA-4 therapy: enhancing efficacy while avoiding toxicity

Marabelle, Aurélien ; Kohrt, Holbrook ; Levy, Ronald

Clinical cancer research : an official journal of the American Association for Cancer Research, 01 October 2013, Vol.19(19), pp.5261-3 [Peer Reviewed Journal]

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Neutrophils give us a shock

Lowell, Clifford

Journal of Clinical Investigation, Apr 2011, pp.1260-3 [Peer Reviewed Journal]

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15
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Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma

Comin-Anduix, Begoña ; Sazegar, Hooman ; Chodon, Thinle ; Matsunaga, Douglas ; Jalil, Jason ; Von Euw, Erika ; Escuin-Ordinas, Helena ; Balderas, Robert ; Chmielowski, Bartosz ; Gomez-Navarro, Jesus ; Koya, Richard C ; Ribas, Antoni

PloS one, 15 September 2010, Vol.5(9), pp.e12711 [Peer Reviewed Journal]

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Integrin-blocking antibodies delay keratinocyte re-epithelialization in a human three-dimensional wound healing model

Egles, Christophe ; Huet, Heather A ; Dogan, Furkan ; Cho, Sam ; Dong, Shumin ; Smith, Avi ; Knight, Elana B ; Mclachlan, Karen R ; Garlick, Jonathan A

PloS one, 21 May 2010, Vol.5(5), pp.e10528 [Peer Reviewed Journal]

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17
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Rapid desensitization of mice with anti-FcγRIIb/FcγRIII mAb safely prevents IgG-mediated anaphylaxis

Khodoun, Marat V ; Kucuk, Zeynep Yesim ; Strait, Richard T ; Krishnamurthy, Durga ; Janek, Kevin ; Clay, Corey D ; Morris, Suzanne C ; Finkelman, Fred D

The Journal of allergy and clinical immunology, December 2013, Vol.132(6), pp.1375-87 [Peer Reviewed Journal]

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Expression analysis and specific blockade of the receptor for human thymic stromal lymphopoietin (TSLP) by novel antibodies to the human TSLPRα receptor chain

Borowski, Andreas ; Vetter, Tina ; Kuepper, Michael ; Wohlmann, Andreas ; Krause, Sebastian ; Lorenzen, Thomas ; Virchow, Johann Christian ; Luttmann, Werner ; Friedrich, Karlheinz

Cytokine, February 2013, Vol.61(2), pp.546-55 [Peer Reviewed Journal]

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Contamination with recombinant IFN accounts for the unexpected stimulatory properties of commonly used IFN-blocking antibodies

Moll, Herwig P ; Freudenthaler, Harald ; Zommer, Anna ; Buchberger, Elisabeth ; Lin, Xiao-Hong ; Crisafulli, Sara ; Pandya, Yognandan ; Pestka, Sidney ; Lavoie, Thomas ; Brostjan, Christine

European Journal of Immunology, Jan 2011, pp.252-4 [Peer Reviewed Journal]

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20
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Antibody-mediated inhibition of FXIIa blocks downstream bradykinin generation

Cao, Helen ; Biondo, Mark ; Lioe, Hadi ; Busfield, Samantha ; Rayzman, Veronika ; Nieswandt, Bernhard ; Bork, Konrad ; Harrison, Leonard C ; Auyeung, Priscilla ; Farkas, Henriette ; Csuka, Dorottya ; Pelzing, Matthias ; Dower, Steve ; Wilson, Michael J ; Nash, Andrew ; Nolte, Marc W ; Panousis, Con

The Journal of allergy and clinical immunology, October 2018, Vol.142(4), pp.1355-1358 [Peer Reviewed Journal]

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21
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Gene expression profiling identifies sST2 as an effector of ErbB2-driven breast carcinoma cell motility, associated with metastasis

Gillibert-Duplantier, J ; Duthey, B ; Sisirak, V ; Salaün, D ; Gargi, T ; Trédan, O ; Finetti, P ; Bertucci, F ; Birnbaum, D ; Bendriss-Vermare, N ; Badache, A

Oncogene, Jul 26, 2012, pp.3516-24 [Peer Reviewed Journal]

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22
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Signaling through the interleukin-18 receptor [alpha] attenuates inflammation in cisplatin-induced acute kidney injury

Nozaki, Yuji ; Kinoshita, Koji ; Yano, Tomohiro ; Asato, Kayo ; Shiga, Toshihiko ; Hino, Shoichi ; Niki, Kaoru ; Nagare, Yasuaki ; Kishimoto, Kazuya ; Shimazu, Hideki ; Funauchi, Masanori ; Matsumura, Itaru

Kidney International, Oct 2012, pp.892-902 [Peer Reviewed Journal]

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23
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PD-1 blockade in chronically HIV-1-infected humanized mice suppresses viral loads

Seung, Edward ; Dudek, Timothy E ; Allen, Todd M ; Freeman, Gordon J ; Luster, Andrew D ; Tager, Andrew M

PloS one, 2013, Vol.8(10), pp.e77780 [Peer Reviewed Journal]

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24
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Increased Cyclosporine Concentrations in the Absence of Cyclosporine Administration/Commentary/Commentary

Peter, Andreas ; Shipkova, Maria ; Wieland, Eberhard ; Schleicher, Erwin ; Müller, Ingo ; Butch, Anthony ; Milone, Michael

Clinical Chemistry, May 2011, pp.670-3 [Peer Reviewed Journal]

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25
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Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention

Liu, Yang ; Zhang, Fuchun ; Liu, Jianying ; Xiao, Xiaoping ; Zhang, Siyin ; Qin, Chengfeng ; Xiang, Ye ; Wang, Penghua ; Cheng, Gong

PLoS pathogens, February 2014, Vol.10(2), pp.e1003931 [Peer Reviewed Journal]

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26
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Agonistic anti-CD40 therapy synergizes with LAG-3-blocking antibodies


Müller, Philipp ; Thommen, Daniela S ; Zippelius, Alfred

International journal of clinical pharmacology and therapeutics, August 2017, Vol.55(8), pp.692-694 [Peer Reviewed Journal]

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27
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A CD11d Monoclonal Antibody Treatment Reduces Tissue Injury and Improves Neurological Outcome after Fluid Percussion Brain Injury in Rats

Bao, Feng ; Shultz, Sandy ; Hepburn, Jeff ; Omana, Vanessa ; Weaver, Lynne ; Cain, Donald ; Brown, Arthur

Journal of Neurotrauma, Sep 20, 2012, pp.2375-92 [Peer Reviewed Journal]

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28
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Delayed Anti-Nogo-A Antibody Application after Spinal Cord Injury Shows Progressive Loss of Responsiveness

Gonzenbach, Roman ; Zoerner, Bjoern ; Schnell, Lisa ; Weinmann, Oliver ; Mir, Anis ; Schwab, Martin

Journal of Neurotrauma, Feb 10, 2012, pp.567-78 [Peer Reviewed Journal]

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29
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Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice

Lau, Janet ; Cheung, Jeanne ; Navarro, Armando ; Lianoglou, Steve ; Haley, Benjamin ; Totpal, Klara ; Sanders, Laura ; Koeppen, Hartmut ; Caplazi, Patrick ; Mcbride, Jacqueline ; Chiu, Henry ; Hong, Rebecca ; Grogan, Jane ; Javinal, Vincent ; Yauch, Robert ; Irving, Bryan ; Belvin, Marcia ; Mellman, Ira ; Kim, Jeong M ; Schmidt, Maike

Nature communications, 21 February 2017, Vol.8, pp.14572 [Peer Reviewed Journal]

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Characterization of Plasmodium vivax transmission-blocking activity in low to moderate malaria transmission settings of the Colombian Pacific coast

Arévalo-Herrera, Myriam ; Solarte, Yezid ; Rocha, Leonardo ; Alvarez, Diego ; Beier, John C ; Herrera, Sócrates

The American journal of tropical medicine and hygiene, February 2011, Vol.84(2 Suppl), pp.71-7 [Peer Reviewed Journal]

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31
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CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

Kojima, Yoko ; Volkmer, Jens-Peter ; Mckenna, Kelly ; Civelek, Mete ; Lusis, Aldons Jake ; Miller, Clint L ; Direnzo, Daniel ; Nanda, Vivek ; Ye, Jianqin ; Connolly, Andrew J ; Schadt, Eric E ; Quertermous, Thomas ; Betancur, Paola ; Maegdefessel, Lars ; Matic, Ljubica Perisic ; Hedin, Ulf ; Weissman, Irving L ; Leeper, Nicholas J

Nature, 04 August 2016, Vol.536(7614), pp.86-90 [Peer Reviewed Journal]

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32
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Interleukin-19: a new target to aim for?

Fielding, Ceri A

Rheumatology (Oxford, England), March 2012, Vol.51(3), pp.399-400 [Peer Reviewed Journal]

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33
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Ustekinumab for the treatment of Crohn's disease

Khanna, Reena ; Feagan, Brian

Immunotherapy, Aug 2013, Vol.5(8), pp.803-15 [Peer Reviewed Journal]

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34
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Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies

Wright, Katherine E ; Hjerrild, Kathryn A ; Bartlett, Jonathan ; Douglas, Alexander D ; Jin, Jing ; Brown, Rebecca E ; Illingworth, Joseph J ; Ashfield, Rebecca ; Clemmensen, Stine B ; De Jongh, Willem A ; Draper, Simon J ; Higgins, Matthew K

Nature, 20 November 2014, Vol.515(7527), pp.427-30 [Peer Reviewed Journal]

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35
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Facilitated antigen presentation and its inhibition by blocking IgG antibodies depends on IgE repertoire complexity

Holm, Jens ; Willumsen, Nicholas ; Würtzen, Peter A ; Christensen, Lars H ; Lund, Kaare

The Journal of allergy and clinical immunology, April 2011, Vol.127(4), pp.1029-37 [Peer Reviewed Journal]

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Interleukin-19 blockade attenuates collagen-induced arthritis in rats

Hsu, Yu-Hsiang ; Hsieh, Pei-Pei ; Chang, Ming-Shi

Rheumatology (Oxford, England), March 2012, Vol.51(3), pp.434-42 [Peer Reviewed Journal]

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