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1
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TLR4 siRNA inhibits proliferation and invasion in colorectal cancer cells by downregulating ACAT1 expression

Ye, Kai ; Wu, Yiyang ; Sun, Yafeng ; Lin, Jian'an ; Xu, Jianhua

Life Sciences, 15 June 2016, Vol.155, pp.133-139 [Peer Reviewed Journal]

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Increased expression of acyl-coenzyme A: cholesterol acyltransferase-1 and elevated cholesteryl esters in the hippocampus after excitotoxic injury

Kim, J.-H ; Ee, S.-M ; Jittiwat, J ; Ong, E.-S ; Farooqui, A.A ; Jenner, A.M ; Ong, W.-Y

Neuroscience, 2011, Vol.185, pp.125-134 [Peer Reviewed Journal]

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3
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MiR-21 regulates the ACAT1 gene in MCF-7 cells

Chanyshev, M.D ; Razumova, Y.V ; Ovchinnikov, V.Y ; Gulyaeva, L.F

Life Sciences, 15 September 2018, Vol.209, pp.173-178 [Peer Reviewed Journal]

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4
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Insulin promotes progression of colon cancer by upregulation of ACAT1

Chen, Xin ; Liang, Huiling ; Song, Qibin ; Xu, Ximing ; Cao, Dedong

Lipids in Health and Disease, 2018, Vol.17 [Peer Reviewed Journal]

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5
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Foam cells in atherosclerosis

Yu, Xiao-Hua ; Fu, Yu-Chang ; Zhang, Da-Wei ; Yin, Kai ; Tang, Chao-Ke

Clinica Chimica Acta, 23 September 2013, Vol.424, pp.245-252 [Peer Reviewed Journal]

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6
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Neuronal cholesterol esterification by ACAT1 in Alzheimer's disease

Chang, Ta‐Yuan ; Chang, Catherine C. Y. ; Bryleva, Elena ; Rogers, Maximillian A. ; Murphy, Stephanie R.

IUBMB Life, April 2010, Vol.62(4), pp.261-267 [Peer Reviewed Journal]

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7
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Potent DGAT1 Inhibitors in the Benzimidazole Class with a Pyridyl-oxy-cyclohexanecarboxylic Acid Moiety

He, Shuwen ; Hong, Qingmei ; Lai, Zhong ; Wu, Zhicai ; Yu, Yang ; Kim, David W ; Ting, Pauline C ; Kuethe, Jeffrey T ; Yang, Ginger X ; Jian, Tianying ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto D ; Sperbeck, Donald M ; Sonatore, Lisa M ; Wiltsie, Judyann ; Chung, Christine C ; Gibson, Jack T ; Lisnock, Jeanmarie ; Murphy, Beth A ; Gorski, Judith N ; Liu, Jinqi ; Chen, Dunlu ; Chen, Xiaoli ; Wolff, Michael ; Tong, Sharon X ; Madeira, Maria ; Karanam, Bindhu V ; Shen, Dong-Ming ; Balkovec, James M ; Pinto, Shirly ; Nargund, Ravi P ; Devita, Robert J

ACS medicinal chemistry letters, 08 August 2013, Vol.4(8), pp.773-8 [Peer Reviewed Journal]

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8
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Metabolic encephalopathy in beta-ketothiolase deficiency: The first report from India

Akella, Radha Rama Devi ; Aoyama, Yuka ; Mori, Chihiro ; Lingappa, Lokesh ; Cariappa, Rohit ; Fukao, Toshiyuki

Brain and Development, June 2014, Vol.36(6), pp.537-540 [Peer Reviewed Journal]

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9
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Expression of miR-21 and its Acat1 , Armcx1 , and Pten target genes in liver of female rats treated with DDT and benzo[a]pyrene

Chanyshev, M. ; Ushakov, D. ; Gulyaeva, L.

Molecular Biology, 2017, Vol.51(4), pp.586-591 [Peer Reviewed Journal]

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10
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miR-467b regulates the cholesterol ester formation via targeting ACAT1 gene in RAW 264.7 macrophages

Wang, Bo ; He, Ping-Ping ; Zeng, Gao-Feng ; Zhang, Tao ; Ou Yang, Xin-Ping

Biochimie, January 2017, Vol.132, pp.38-44 [Peer Reviewed Journal]

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11
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MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophages

Zhang, Min ; Wu, Jian-Feng ; Chen, Wu-Jun ; Tang, Shi-Lin ; Mo, Zhong-Cheng ; Tang, Yan-Yan ; Li, Yuan ; Wang, Jia-Lin ; Liu, Xiang-Yu ; Peng, Juan ; Chen, Kong ; He, Ping-Ping ; Lv, Yun-Cheng ; Ouyang, Xin-Ping ; Yao, Feng ; Tang, Deng-Pei ; Cayabyab, Francisco S ; Zhang, Da-Wei ; Zheng, Xi-Long ; Tian, Guo-Ping ; Tang, Chao-Ke

Atherosclerosis, May 2014, Vol.234(1), pp.54-64 [Peer Reviewed Journal]

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12
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Two Libyan siblings with beta-ketothiolase deficiency: A case report and review of literature

Abdelkreem, Elsayed ; Alobaidy, Hanna ; Aoyama, Yuka ; Mahmoud, Shaimaa ; Abd El Aal, Mohamed ; Fukao, Toshiyuki

Egyptian Journal of Medical Human Genetics, April 2017, Vol.18(2), pp.199-203 [Peer Reviewed Journal]

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13
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Urotensin II differentially regulates macrophage and hepatic cholesterol homeostasis

Kiss, Robert S ; You, Zhipeng ; Genest, Jacques ; Behm, David J ; Giaid, Adel

Peptides, 2011, Vol.32(5), pp.956-963 [Peer Reviewed Journal]

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14
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High ACAT1 expression in estrogen receptor negative basal-like breast cancer cells is associated with LDL-induced proliferation

Antalis, Caryl ; Arnold, Tyler ; Rasool, Tamkeen ; Lee, Bonggi ; Buhman, Kimberly ; Siddiqui, Rafat

Breast Cancer Research and Treatment, 2010, Vol.122(3), pp.661-670 [Peer Reviewed Journal]

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15
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Single‐nucleotide substitution T to A in the polypyrimidine stretch at the splice acceptor site of intron 9 causes exon 10 skipping in the ACAT 1 gene

Sasai, Hideo ; Aoyama, Yuka ; Otsuka, Hiroki ; Abdelkreem, Elsayed ; Nakama, Mina ; Hori, Tomohiro ; Ohnishi, Hidenori ; Turner, Lesley ; Fukao, Toshiyuki

Molecular Genetics & Genomic Medicine, 2017, Vol.5(2), p.177-184 [Peer Reviewed Journal]

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16
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Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety

He, Shuwen ; Hong, Qingmei ; Lai, Zhong ; Yang, David X ; Ting, Pauline C ; Kuethe, Jeffrey T ; Cernak, Timothy A ; Dykstra, Kevin D ; Sperbeck, Donald M ; Wu, Zhicai ; Yu, Yang ; Yang, Ginger X ; Jian, Tianying ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto D ; Sonatore, Lisa M ; Wiltsie, Judyann ; Liu, Jinqi ; Gorski, Judith N ; Chung, Christine C ; Gibson, Jack T ; Lisnock, Jeanmarie ; Xiao, Jianying ; Wolff, Michael ; Tong, Sharon X ; Madeira, Maria ; Karanam, Bindhu V ; Shen, Dong-Ming ; Balkovec, James M ; Pinto, Shirly ; Nargund, Ravi P ; Devita, Robert J

ACS medicinal chemistry letters, 09 October 2014, Vol.5(10), pp.1082-7 [Peer Reviewed Journal]

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17
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Clinical and Mutational Characterizations of Ten Indian Patients with Beta-Ketothiolase Deficiency

Abdelkreem, Elsayed ; Akella, Radha Rama Devi ; Dave, Usha ; Sane, Sudhir ; Otsuka, Hiroki ; Sasai, Hideo ; Aoyama, Yuka ; Nakama, Mina ; Ohnishi, Hidenori ; Mahmoud, Shaimaa ; Abd El Aal, Mohamed ; Fukao, Toshiyuki

JIMD reports, 2017, Vol.35, pp.59-65

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18
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Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression

Saraon, Punit ; Trudel, Dominique ; Kron, Ken ; Dmitromanolakis, Apostolos ; Trachtenberg, John ; Bapat, Bharati ; van Der Kwast, Theodorus ; Jarvi, Keith A ; Diamandis, Eleftherios P

The Prostate, Apr 2014, Vol.74(4), pp.372-80 [Peer Reviewed Journal]

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19
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ACAT-selective and Nonselective DGAT1 Inhibition: Adrenocortical Effects—A Cross-species Comparison

Floettmann, Jan Eike ; Buckett, Linda K ; Turnbull, Andrew V ; Smith, Tim ; Hallberg, Carina ; Birch, Alan ; Lees, David ; Jones, Huw B

Toxicologic Pathology, October 2013, Vol.41(7), pp.941-950 [Peer Reviewed Journal]

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20
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Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation

Still, Amelia J ; Floyd, Brendan J ; Hebert, Alexander S ; Bingman, Craig A ; Carson, Joshua J ; Gunderson, Drew R ; Dolan, Brendan K ; Grimsrud, Paul A ; Dittenhafer-Reed, Kristin E ; Stapleton, Donald S ; Keller, Mark P ; Westphall, Michael S ; Denu, John M ; Attie, Alan D ; Coon, Joshua J ; Pagliarini, David J

The Journal of biological chemistry, 06 September 2013, Vol.288(36), pp.26209-19 [Peer Reviewed Journal]

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21
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Ketolytic and glycolytic enzymatic expression profiles in malignant gliomas: implication for ketogenic diet therapy

Chang, Howard T ; Olson, Lawrence Karl ; Schwartz, Kenneth A

Nutrition & Metabolism, 2013, Vol.10, p.47-47 [Peer Reviewed Journal]

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22
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High-Density Lipoprotein and Coronary Heart Disease

Natarajan, Pradeep ; Ray, Kausik ; Cannon, Christopher

Journal of the American College of Cardiology, Mar 30, 2010, Vol.55(13), pp.1283-99 [Peer Reviewed Journal]

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23
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Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene

Hu, Guang-Jing ; Chen, Jia ; Zhao, Xiao-Nan ; Xu, Jia-Jia ; Guo, Dong-Qing ; Lu, Ming ; Zhu, Ming ; Xiong, Ying ; Li, Qin ; Chang, Catherine ; Song, Bao-Liang ; Chang, Ta-Yuan ; Li, Bo-Liang

Cell Research, Aug 2013, Vol.23(8), pp.1007-24 [Peer Reviewed Journal]

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24
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Docosahexaenoic acid is a substrate for ACAT1 and inhibits cholesteryl ester formation from oleic acid in MCF-10A cells

Antalis, Caryl J ; Arnold, Tyler ; Lee, Bonggi ; Buhman, Kimberley K ; Siddiqui, Rafat A

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 2009, Vol.80(2), pp.165-171 [Peer Reviewed Journal]

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25
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Targeting PLIN2/PLIN5-PPARγ: SFN Disturbs the Maturation of Lipid Droplets

Tian, Sicong ; Lei, Peng ; Teng, Chunying ; Sun, Yao ; Song, Xinyue ; Li, Baolong ; Shan, Yujuan

Molecular nutrition & food research, 19 July 2019, pp.e1900183 [Peer Reviewed Journal]

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26
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Atheroprotective Effects of Tumor Necrosis Factor-Stimulated Gene-6

Watanabe, Rena ; Watanabe, Hitomi ; Takahashi, Yui ; Kojima, Miho ; Konii, Hanae ; Watanabe, Kaho ; Shirai, Remina ; Sato, Kengo ; Matsuyama, Taka-Aki ; Ishibashi-Ueda, Hatsue ; Iso, Yoshitaka ; Koba, Shinji ; Kobayashi, Youichi ; Hirano, Tsutomu ; Watanabe, Takuya

JACC. Basic to translational science, October 2016, Vol.1(6), pp.494-509 [Peer Reviewed Journal]

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27
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Sex-specific association of ACAT-1 rs1044925 SNP and serum lipid levels in the hypercholesterolemic subjects

Wu, Dong-Feng ; Yin, Rui-Xing ; Aung, Lynn Htet Htet ; Li, Qing ; Yan, Ting-Ting ; Zeng, Xiao-Na ; Huang, Ke-Ke ; Huang, Ping ; Wu, Jin-Zhen ; Pan, Shang-Ling

Lipids in Health and Disease, 2012, Vol.11, p.9 [Peer Reviewed Journal]

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28
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Apolipoprotein A-I Helsinki promotes intracellular acyl-CoA cholesterol acyltransferase (ACAT) protein accumulation

Toledo, Juan ; Garda, Horacio ; Cabaleiro, Laura ; Cuellar, Angela ; Pellon-Maison, Magali ; Gonzalez-Baro, Maria ; Gonzalez, Marina

Molecular and Cellular Biochemistry, May 2013, Vol.377(1-2), pp.197-205 [Peer Reviewed Journal]

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29
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Single base substitutions at the initiator codon in the mitochondrial acetoacetyl‐CoA thiolase (ACAT1/T2) gene result in production of varying amounts of wild‐type T2 polypeptide

Fukao, Toshiyuki ; Matsuo, Naoki ; Zhang, Gai Xiu ; Urasawa, Rintaro ; Kubo, Tetsuo ; Kohno, Yoshinori ; Kondo, Naomi

Human Mutation, June 2003, Vol.21(6), pp.587-592 [Peer Reviewed Journal]

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30
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Mutation update on ACAT1 variants associated with mitochondrial acetoacetyl‐CoA thiolase (T2) deficiency

Abdelkreem, Elsayed ; Harijan, Rajesh K. ; Yamaguchi, Seiji ; Wierenga, Rikkert K. ; Fukao, Toshiyuki

Human Mutation, October 2019, Vol.40(10), pp.1641-1663 [Peer Reviewed Journal]

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31
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Cholesterol regulates ACAT2 gene expression and enzyme activity in human hepatoma cells

Pramfalk, Camilla ; Angelin, Bo ; Eriksson, Mats ; Parini, Paolo

Biochemical and Biophysical Research Communications, 2007, Vol.364(2), pp.402-409 [Peer Reviewed Journal]

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32
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Two Infants With Beta-Ketothiolase Deficiency Identified by Newborn Screening in China

Yuqi Yang ; Shu Hong Jiang ; Shuang Liu ; Xiao Ya Han ; Ying Wang ; Lei Lei Wang ; Bin Yu

Frontiers in Genetics, 01 May 2019, Vol.10 [Peer Reviewed Journal]

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33
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Acyl coenzyme A: cholesterol acyltransferase inhibition and hepatic apolipoprotein B secretion

Burnett, John R ; Wilcox, Lisa J ; Huff, Murray W

Clinica Chimica Acta, August 1999, Vol.286(1-2), pp.231-242 [Peer Reviewed Journal]

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34
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Apelin and its receptor APJ in cardiovascular diseases

Yu, Xiao-Hua ; Tang, Zhi-Bin ; Liu, Li-Jing ; Qian, Hong ; Tang, Shi-Lin ; Zhang, Da-Wei ; Tian, Guo-Ping ; Tang, Chao-Ke

Clinica chimica acta; international journal of clinical chemistry, 20 January 2014, Vol.428, pp.1-8 [Peer Reviewed Journal]

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35
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Accelerating the discovery of DGAT1 inhibitors through the application of parallel medicinal chemistry (PMC)

Yu, Yang ; Wu, Zhicai ; Shi, Zhi-Cai ; He, Shuwen ; Lai, Zhong ; Cernak, Timothy A ; Vachal, Petr ; Liu, Min ; Liu, Jian ; Hong, Qingmei ; Jian, Tianying ; Guiadeen, Deodial ; Krikorian, Arto ; Sperbeck, Donald M ; Verras, Andreas ; Sonatore, Lisa M ; Murphy, Beth A ; Wiltsie, Judyann ; Chung, Christine C ; Gorski, Judith N ; Liu, Jinqi ; Xiao, Jianying ; Wolff, Michael ; Tong, Sharon X ; Madeira, Maria ; Karanam, Bindhu V ; Shen, Dong-Ming ; Balkovec, James M ; De Vita, Robert J ; Pinto, Shirly ; Nargund, Ravi P

Bioorganic & Medicinal Chemistry Letters, 01 June 2019, Vol.29(11), pp.1380-1385 [Peer Reviewed Journal]

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36
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Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential : a molecular and clinicopathological study

Gonzalo Calvo, David De ; López Vilaró, Laura ; Nasarre, Laura ; Perez Olabarria, Maitane ; Vázquez, Tania ; Escuin I Borràs, Daniel ; Badimón Maestro, Lina ; Barnadas Molins, Agustí ; Lerma Puertas, Enrique ; Llorente Cortés, Vicenta

BMC Cancer ; Vol. 15 N. 460 (June 2015), p. 1-13

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37
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Insulin induces human acyl-coenzyme A: cholesterol acyltransferase1 gene expression via MAP kinases and CCAAT/enhancer-binding protein [alpha]

Ge, Jing ; Zhai, Wei ; Cheng, Bei ; He, Ping ; Qi, Benling ; Lu, Han ; Zeng, Yongli ; Chen, Xin

Journal of Cellular Biochemistry, Sep 2013, Vol.114(9), pp.2188-98 [Peer Reviewed Journal]

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