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6 Results  for Everything (Includes Articles)

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Liver X receptor agonists as potential therapeutic agents for dyslipidemia and atherosclerosis

Lund, Erik G ; Menke, John G ; Sparrow, Carl P

Arteriosclerosis, thrombosis, and vascular biology, 01 July 2003, Vol.23(7), pp.1169-77 [Peer Reviewed Journal]

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A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux

Sparrow, Carl P ; Baffic, Joanne ; Lam, My-Hanh ; Lund, Erik G ; Adams, Alan D ; Fu, Xuan ; Hayes, Nancy ; Jones, A Brian ; Macnaul, Karen L ; Ondeyka, John ; Singh, Sheo ; Wang, Jianhua ; Zhou, Gaochao ; Moller, David E ; Wright, Samuel D ; Menke, John G

The Journal of biological chemistry, 22 March 2002, Vol.277(12), pp.10021-7 [Peer Reviewed Journal]

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SAR studies: Designing potent and selective LXR agonists

Szewczyk, Jason W ; Huang, Shaei ; Chin, Jayne ; Tian, Jenny ; Mitnaul, Lyndon ; Rosa, Raymond L ; Peterson, Larry ; Sparrow, Carl P ; Adams, Alan D

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(11), pp.3055-3060 [Peer Reviewed Journal]

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Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis

Liu, Weiguo ; Chen, Steve ; Dropinski, James ; Colwell, Lawrence ; Robins, Michael ; Szymonifka, Michael ; Hayes, Nancy ; Sharma, Neelam ; Macnaul, Karen ; Hernandez, Melba ; Burton, Charlotte ; Sparrow, Carl P ; Menke, John G ; Singh, Sheo B

Bioorganic & medicinal chemistry letters, 15 October 2005, Vol.15(20), pp.4574-8 [Peer Reviewed Journal]

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Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters

Singh, Sheo B ; Ondeyka, John G ; Liu, Weiguo ; Chen, Steve ; Chen, Tom S ; Li, Xiaohua ; Bouffard, Aileen ; Dropinski, James ; Jones, A. Brian ; Mccormick, Sherrie ; Hayes, Nancy ; Wang, Jianhua ; Sharma, Neelam ; Macnaul, Karen ; Hernandez, Melba ; Chao, Yu-Sheng ; Baffic, Joanne ; Lam, My-Hanh ; Burton, Charlotte ; Sparrow, Carl P

Bioorganic & Medicinal Chemistry Letters, 2005, Vol.15(11), pp.2824-2828 [Peer Reviewed Journal]

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Different roles of liver X receptor α and β in lipid metabolism: Effects of an α-selective and a dual agonist in mice deficient in each subtype

Lund, Erik G ; Peterson, Laurence B ; Adams, Alan D ; Lam, My-Hanh N ; Burton, Charlotte A ; Chin, Jayne ; Guo, Qiu ; Huang, Shaei ; Latham, Melanie ; Lopez, Jacqueline C ; Menke, John G ; Milot, Denise P ; Mitnaul, Lyndon J ; Rex-Rabe, Sandra E ; Rosa, Raymond L ; Tian, Jenny Y ; Wright, Samuel D ; Sparrow, Carl P

Biochemical Pharmacology, 2006, Vol.71(4), pp.453-463 [Peer Reviewed Journal]

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