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Discovery of 3-morpholino-imidazole[1,5-a]pyrazine BTK inhibitors for rheumatoid arthritis

Boga, Sobhana Babu ; Alhassan, Abdul-Basit ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto ; Gao, Xiaolei ; Wang, James ; Yu, Younong ; Anand, Rajan ; Liu, Shilan ; Yang, Chundao ; Wu, Hao ; Cai, Jiaqiang ; Zhu, Hugh ; Desai, Jagdish ; Maloney, Kevin ; Gao, Ying-Duo ; Fischmann, Thierry O ; Presland, Jeremy ; Mansueto, My ; Xu, Zangwei ; Leccese, Erica ; Knemeyer, Ian ; Garlisi, Charles G ; Bays, Nathan ; Stivers, Peter ; Brandish, Philip E ; Hicks, Alexandra ; Cooper, Alan ; Kim, Ronald M ; Kozlowski, Joseph A

Bioorganic & Medicinal Chemistry Letters, 15 August 2017, Vol.27(16), pp.3939-3943 [Peer Reviewed Journal]

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