skip to main content
Language:
Primo Advanced Search
Primo Advanced Search Query Term
Primo Advanced Search Query Term
Primo Advanced Search prefilters

11 Results  for Everything (Includes Articles)

Refined by: Subject: Medicine remove
Result Number Material Type Add to My Shelf Action Record Details and Options
1
Material Type:
Article
Add to e-Shelf

Tumour necrosis factor-alpha stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-kappaB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b

Dulos, John ; Kaptein, Allard ; Kavelaars, Annemieke ; Heijnen, Cobi ; Boots, Annemieke

Arthritis research & therapy, 2005, Vol.7(6), pp.R1271-80 [Peer Reviewed Journal]

Full text available

View all versions
2
Material Type:
Article
Add to e-Shelf

In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation

Vink, Paul M ; Smout, Wendy M ; Driessen-Engels, Lilian J ; De Bruin, Alex M ; Delsing, Dianne ; Krajnc-Franken, Magda A ; Jansen, Aswin J ; Rovers, Eric F ; Van Puijenbroek, André A ; Kaptein, Allard ; Nolte, Martijn A ; Garritsen, Anja ; Van Eenennaam, Hans

PloS one, 2013, Vol.8(3), pp.e57348 [Peer Reviewed Journal]

Full text available

View all versions
3
Material Type:
Article
Add to e-Shelf

The Bruton Tyrosine Kinase (BTK) Inhibitor Acalabrutinib Demonstrates Potent On-Target Effects and Efficacy in Two Mouse Models of Chronic Lymphocytic Leukemia

Herman, Sarah E M ; Montraveta, Arnau ; Niemann, Carsten U ; Mora-Jensen, Helena ; Gulrajani, Michael ; Krantz, Fanny ; Mantel, Rose ; Smith, Lisa L ; Mcclanahan, Fabienne ; Harrington, Bonnie K ; Colomer, Dolors ; Covey, Todd ; Byrd, John C ; Izumi, Raquel ; Kaptein, Allard ; Ulrich, Roger ; Johnson, Amy J ; Lannutti, Brian J ; Wiestner, Adrian ; Woyach

Clinical cancer research : an official journal of the American Association for Cancer Research, 01 June 2017, Vol.23(11), pp.2831-2841 [Peer Reviewed Journal]

Full text available

4
Material Type:
Article
Add to e-Shelf

Novel ATP competitive MK2 inhibitors with potent biochemical and cell-based activity throughout the series

Oubrie, Arthur ; Kaptein, Allard ; de Zwart, Edwin ; Hoogenboom, Niels ; Goorden, Rianne ; van de Kar, Bas ; van Hoek, Maaike ; de Kimpe, Vera ; van Der Heijden, Ruud ; Borsboom, Judith ; Kazemier, Bert ; de Roos, Jeroen ; Scheffers, Michiel ; Lommerse, Jos ; Schultz-Fademrecht, Carsten ; Barf, Tjeerd

Bioorganic & Medicinal Chemistry Letters, 01 January 2012, Vol.22(1), pp.613-618 [Peer Reviewed Journal]

Full text available

View all versions
5
Material Type:
Article
Add to e-Shelf

Discovery of selective and orally available spiro-3-piperidyl ATP-competitive MK2 inhibitors

Kaptein, Allard ; Oubrie, Arthur ; Zwart, Edwin de ; Hoogenboom, Niels ; Wit, Joeri de ; Kar, Bas van de ; Hoek, Maaike van ; Vogel, Gerard ; Kimpe, Vera de ; Schultz-Fademrecht, Carsten ; Borsboom, Judith ; Zeeland, Mario van ; Versteegh, Judith ; Kazemier, Bert ; Roos, Jeroen de ; Wijnands, Frank ; Dulos, John ; Jaeger, Martin ; Leandro-Garcia, Paula ; Barf, Tjeerd

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(12), pp.3823-3827 [Peer Reviewed Journal]

Full text available

View all versions
6
Material Type:
Article
Add to e-Shelf

Structure-based lead identification of ATP-competitive MK2 inhibitors

Barf, Tjeerd ; Kaptein, Allard ; Wilde, Sander de ; Heijden, Ruud van Der ; Someren, Richard van ; Demont, Dennis ; Schultz-Fademrecht, Carsten ; Versteegh, Judith ; Zeeland, Mario van ; Seegers, Nicole ; Kazemier, Bert ; Kar, Bas van de ; Hoek, Maaike van ; Roos, Jeroen de ; Klop, Henri ; Smeets, Ruben ; Hofstra, Claudia ; Hornberg, Jorrit ; Oubrie, Arthur

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(12), pp.3818-3822 [Peer Reviewed Journal]

Full text available

View all versions
7
Material Type:
Article
Add to e-Shelf

6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors

Cai, Jiaqiang ; Baugh, Mark ; Black, Darcey ; Long, Clive ; Jonathan Bennett, D ; Dempster, Maureen ; Fradera, Xavier ; Gillespie, Jonathan ; Andrews, Fiona ; Boucharens, Sylviane ; Bruin, John ; Cameron, Kenneth S ; Cumming, Iain ; Hamilton, William ; Jones, Philip S ; Kaptein, Allard ; Kinghorn, Emma ; Maidment, Maurice ; Martin, Iain ; Mitchell, Ann

Bioorganic & Medicinal Chemistry Letters, 01 August 2010, Vol.20(15), pp.4350-4354 [Peer Reviewed Journal]

Full text available

View all versions
8
Material Type:
Article
Add to e-Shelf

Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia

Byrd, John C ; Harrington, Bonnie ; O'Brien, Susan ; Jones, Jeffrey A ; Schuh, Anna ; Devereux, Steve ; Chaves, Jorge ; Wierda, William G ; Awan, Farrukh T ; Brown, Jennifer R ; Hillmen, Peter ; Stephens, Deborah M ; Ghia, Paolo ; Barrientos, Jacqueline C ; Pagel, John M ; Woyach, Jennifer ; Johnson, Dave ; Huang, Jane ; Wang

The New England journal of medicine, 28 January 2016, Vol.374(4), pp.323-32 [Peer Reviewed Journal]

Full text available

View all versions
9
Material Type:
Article
Add to e-Shelf

Potency and Selectivity of BTK Inhibitors in Clinical Development for B-Cell Malignancies

Kaptein, Allard ; de Bruin, Gerjan ; Hoek, Maaike Emmelot-van ; van de Kar, Bas ; de Jong, Anouk ; Gulrajani, Michael ; Demont, Dennis ; Covey, Todd ; Mittag, Diana ; Barf, Tjeerd

Clinical Lymphoma, Myeloma and Leukemia, September 2019, Vol.19, pp.S316-S317 [Peer Reviewed Journal]

Full text available

10
Material Type:
Article
Add to e-Shelf

Apolipoprotein E polymorphism affects plasma levels of lipoprotein(a)

de Knijff, Peter ; Kaptein, Allard ; Boomsma, Dorret ; Princen, Hans M.G ; Frants, Rune R ; Havekes, Louis M

Atherosclerosis, 1991, Vol.90(2), pp.169-174 [Peer Reviewed Journal]

Full text available

View all versions
11
Material Type:
Article
Add to e-Shelf

Discovery of quinoline-based irreversible BTK inhibitors

de Bruin, Gerjan ; Demont, Dennis ; de Zwart, Edwin ; Verkaik, Saskia ; Hoogenboom, Niels ; van de Kar, Bas ; van Lith, Bart ; Emmelot- van Hoek, Maaike ; Gulrajani, Michael ; Covey, Todd ; Kaptein, Allard ; Barf, Tjeerd

Bioorganic & Medicinal Chemistry Letters [Peer Reviewed Journal]

Full text available

11 Results  for Everything (Includes Articles)

Refine Search Results

Expand My Results

  1.   

Publication Date 

From To
  1. Before 2005  (1)
  2. 2005 To 2009  (1)
  3. 2010 To 2010  (1)
  4. 2011 To 2012  (3)
  5. After 2012  (4)
  6. More options open sub menu

Suggested New Searches

Ignore my query and look for everything

by this author/creator:

  1. Kaptein, Allard
  2. Kaptein, A
  3. Barf, Tjeerd
  4. Covey, Todd
  5. Gulrajani, Michael

Searching Remote Databases, Please Wait