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12 Results  for Everything (Includes Articles)

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Biphenyl-substituted oxazolidinones as cholesteryl ester transfer protein inhibitors: modifications of the oxazolidinone ring leading to the discovery of anacetrapib

Smith, Cameron J ; Ali, Amjad ; Hammond, Milton L ; Li, Hong ; Lu, Zhijian ; Napolitano, Joann ; Taylor, Gayle E ; Thompson, Christopher F ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Cumiskey, Anne-Marie ; Latham, Melanie ; Peterson, Laurence B ; Rosa

Journal of medicinal chemistry, 14 July 2011, Vol.54(13), pp.4880-95 [Peer Reviewed Journal]

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Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib

Yvan-Charvet, Laurent ; Kling, Jelena ; Pagler, Tamara ; Li, Hongna ; Hubbard, Brian ; Fisher, Tim ; Sparrow, Carl P ; Taggart, Andrew K ; Tall, Alan R

Arteriosclerosis, thrombosis, and vascular biology, July 2010, Vol.30(7), pp.1430-8 [Peer Reviewed Journal]

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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Attenuation of hERG binding and improved HDLc-raising efficacy

Sweis, Ramzi F ; Hunt, Julianne A ; Sinclair, Peter J ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Cumiskey, Anne-Marie ; Latham, Melanie ; Rosa, Raymond ; Peterson, Larry ; Sparrow, Carl P ; Anderson, Matt S

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(9), pp.2597-2600 [Peer Reviewed Journal]

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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Scaffold design and advancement in HDLc-raising efficacy

Sweis, Ramzi F ; Hunt, Julianne A ; Kallashi, Florida ; Hammond, Milton L ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Cumiskey, Anne-Marie ; Latham, Melanie ; Rosa, Raymond ; Peterson, Larry ; Sparrow, Carl P ; Wright, Samuel D ; Anderson, Matt S ; Sinclair, Peter J

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(6), pp.1890-1895 [Peer Reviewed Journal]

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SAR studies on the central phenyl ring of substituted biphenyl oxazolidinone-potent CETP inhibitors

Lu, Zhijian ; Chen, Yi-Heng ; Napolitano, Joann B ; Taylor, Gayle ; Ali, Amjad ; Hammond, Milton L ; Deng, Qiaolin ; Tan, Eugene ; Tong, Xinchun ; Xu, Suoyu S ; Latham, Melanie J ; Peterson, Laurence B ; Anderson, Matt S ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Chen, Ying ; Sparrow, Carl P ; Wright, Samuel D

Bioorganic & Medicinal Chemistry Letters, 01 January 2012, Vol.22(1), pp.199-203 [Peer Reviewed Journal]

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2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety

Smith, Cameron J ; Ali, Amjad ; Chen, Liya ; Hammond, Milton L ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(1), pp.346-349 [Peer Reviewed Journal]

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2-Arylbenzoxazoles as CETP inhibitors: raising HDL-C in cynoCETP transgenic mice

Kallashi, Florida ; Kim, Dooseop ; Kowalchick, Jennifer ; Park, You Jung ; Hunt, Julianne A ; Ali, Amjad ; Smith, Cameron J ; Hammond, Milton L ; Pivnichny, James V ; Tong, Xinchun ; Xu, Suoyu S ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Cumiskey, Anne-Marie ; Latham, Melanie ; Peterson

Bioorganic & medicinal chemistry letters, 01 January 2011, Vol.21(1), pp.558-61 [Peer Reviewed Journal]

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2-Arylbenzoxazoles as CETP inhibitors: Substitution and modification of the α-alkoxyamide moiety

Hunt, Julianne A ; Gonzalez, Silvia ; Kallashi, Florida ; Hammond, Milton L ; Pivnichny, James V ; Tong, Xinchun ; Xu, Suoyu S ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(3), pp.1019-1022 [Peer Reviewed Journal]

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Design of a novel class of biphenyl CETP inhibitors

Lu, Zhijian ; Napolitano, Joann B ; Theberge, Ashleigh ; Ali, Amjad ; Hammond, Milton L ; Tan, Eugene ; Tong, Xinchun ; Xu, Suoyu S ; Latham, Melanie J ; Peterson, Laurence B ; Anderson, Matt S ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Chen, Ying ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(24), pp.7469-7472 [Peer Reviewed Journal]

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A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo

Ni, Yan G ; Di Marco, Stefania ; Condra, Jon H ; Peterson, Laurence B ; Wang, Weirong ; Wang, Fubao ; Pandit, Shilpa ; Hammond, Holly A ; Rosa, Ray ; Cummings, Richard T ; Wood, Dana D ; Liu, Xiaomei ; Bottomley, Matthew J ; Shen, Xun ; Cubbon, Rose M ; Wang, Sheng-Ping ; Johns, Douglas G ; Volpari, Cinzia ; Hamuro, Lora ; Chin

Journal of lipid research, January 2011, Vol.52(1), pp.78-86 [Peer Reviewed Journal]

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An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes

Zhang, Liwen ; Mccabe, Timothy ; Condra, Jon H ; Ni, Yan G ; Peterson, Laurence B ; Wang, Weirong ; Strack, Alison M ; Wang, Fubao ; Pandit, Shilpa ; Hammond, Holly ; Wood, Dana ; Lewis, Dale ; Rosa, Ray ; Mendoza, Vivienne ; Cumiskey, Anne Marie ; Johns, Douglas G ; Hansen, Barbara C ; Shen, Xun ; Geoghagen, Neil ; Jensen

International journal of biological sciences, 2012, Vol.8(3), pp.310-27 [Peer Reviewed Journal]

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A high-precision fluorogenic cholesteryl ester transfer protein assay compatible with animal serum and 3456-well assay technology

Eveland, Suzanne S ; Milot, Denise P ; Guo, Qiu ; Chen, Ying ; Hyland, Sheryl A ; Peterson, Laurence B ; Jezequel-Sur, Sylvie ; O’donnell, Gregory T ; Zuck, Paul D ; Ferrer, Marc ; Strulovici, Berta ; Wagner, John A ; Tanaka, Wesley K ; Hilliard, Deborah A ; Laterza, Omar ; Wright, Samuel D ; Sparrow, Carl P ; Anderson, Matt S

Analytical Biochemistry, 2007, Vol.368(2), pp.239-249 [Peer Reviewed Journal]

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