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13 Results  for Everything (Includes Articles)

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The Dutch‐Belted rabbit: An alternative breed for developmental toxicity testing

Spence, Stan

Birth Defects Research Part B: Developmental and Reproductive Toxicology, October 2003, Vol.68(5), pp.439-448 [Peer Reviewed Journal]

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Decreased ejection fraction induced by a MEK inhibitor in spontaneously hypertensive and Wistar rats: Reversibility following co-administration of lisinopril

Ju, Haisong ; Zhao, Shufang ; Martin, Lori ; Wolak, Eileen ; Hahn, Suzette ; Shenoy, Neeta ; Chandra, Sudeep ; Friedrichs, Greg ; Spence, Stan

Journal of Pharmacological and Toxicological Methods, September 2016, Vol.81, pp.350-350 [Peer Reviewed Journal]

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Histone Deacetylase Inhibitors Prolong Cardiac Repolarization through Transcriptional Mechanisms

Spence, Stan ; Deurinck, Mark ; Ju, Haisong ; Traebert, Martin ; Mclean, Leeanne ; Marlowe, Jennifer ; Emotte, Corinne ; Tritto, Elaine ; Tseng, Min ; Shultz, Michael ; Friedrichs, Gregory S

Toxicological Sciences, 2016, Vol. 153(1), pp.39-54 [Peer Reviewed Journal]

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Assessment of female and male fertility in Sprague–Dawley rats administered vorinostat, a histone deacetylase inhibitor

Wise, L. David ; Spence, Stan ; Saldutti, Louise P. ; Kerr, Janet S.

Birth Defects Research Part B: Developmental and Reproductive Toxicology, February 2008, Vol.83(1), pp.19-26 [Peer Reviewed Journal]

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An alternative Alcian Blue dye variant for the evaluation of fetal cartilage

Redfern, Brian G. ; David Wise, L. ; Spence, Stan

Birth Defects Research Part B: Developmental and Reproductive Toxicology, June 2007, Vol.80(3), pp.171-176 [Peer Reviewed Journal]

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Pharmacological Antagonism of the Slow‐Activating Delayed Rectifying Potassium Channel (I Ks ) Has No Effect on Cochlear Structure and Function in vivo

Whitworth, Craig A. ; Rybak, Leonard P. ; Kemp, Ramon ; Spence, Stan

Pharmacology & Toxicology, January 2001, Vol.88(1), pp.45-50 [Peer Reviewed Journal]

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The Heart Rate-Corrected QT Interval of Conscious Beagle Dogs: A Formula Based on Analysis of Covariance

Spence, Stan ; Soper, Keith ; Hoe, Chao-Min ; Coleman, John

Toxicological Sciences, October 1998, Vol.45(2), pp.247-258 [Peer Reviewed Journal]

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Teratogenic effects of the endothelin receptor antagonist L-753,037 in the rat

Spence, Stan ; Anderson, Charles ; Cukierski, Mark ; Patrick, Darryl

Reproductive Toxicology, 1999, Vol.13(1), pp.15-29 [Peer Reviewed Journal]

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Correction to 6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

Sarver, Patrick ; Acker, Michael ; Bagdanoff, Jeffrey T ; Chen, Zhouliang ; Chen, Ying-Nan ; Chan, Homan ; Firestone, Brant ; Fodor, Michelle ; Fortanet, Jorge ; Hao, Huaixiang ; Hentemann, Murphy ; Jouk, Andriana ; Kato, Mitsunori ; Koenig, Robert ; Labonte, Laura R ; Liu, Gang ; Liu, Shumei ; Liu, Chen ; Mcneill, Eric ; Mohseni, Morvarid ; Shultz, Michael D ; Sendzik, Martin ; Stams, Travis ; Spence, Stan ; Tamez, Victoriano ; Tichkule, Ritesh ; Towler, Christopher ; Wang, Hongyun ; Wang, Ping ; Williams, Sarah L ; Yu, Bing ; Lamarche, Matthew J

Journal of medicinal chemistry, 22 March 2019 [Peer Reviewed Journal]

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Correction to Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors

Bagdanoff, Jeffrey T ; Chen, Zhouliang ; Acker, Michael ; Chen, Ying-Nan ; Chan, Homan ; Dore, Michael ; Firestone, Brant ; Fodor, Michelle ; Fortanet, Jorge ; Hentemann, Murphy ; Kato, Mitsunori ; Koenig, Robert ; Labonte, Laura R ; Liu, Shumei ; Mohseni, Movarid ; Ntaganda, Rukundo ; Sarver, Patrick ; Shultz, Michael D ; Smith, Troy ; Sendzik, Martin ; Stams, Travis ; Spence, Stan ; Towler, Christopher ; Wang, Hongyun ; Wang, Ping ; Williams, Sarah L ; Lamarche, Matthew J

Journal of medicinal chemistry, 22 March 2019 [Peer Reviewed Journal]

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Optimization of Fused-Bicyclic Allosteric SHP2 Inhibitors

Bagdanoff, Jeffrey ; Chen, Zhuoliang ; Acker, Michael G ; Chen, Ying-Nan P ; Chan, Homan ; Doré, Michaël ; Firestone, Brant ; Fodor, Michelle ; Fortanet, Jorge ; Hentemann, Murphy ; Kato, Mitsunori ; Koenig, Robert ; Labonte, Laura R ; Liu, Shumei ; Mohseni, Movarid ; Ntaganda, Rukundo ; Sarver, Patrick ; Smith, Troy ; Sendzik, Martin ; Stams, Travis ; Spence, Stan ; Towler, Christopher S ; Wang, Hongyun ; Wang, Ping ; Williams, Sarah L ; Lamarche, Matthew J

Journal of medicinal chemistry, 28 January 2019 [Peer Reviewed Journal]

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6-Amino-3-Methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

Sarver, Patrick ; Acker, Michael G ; Bagdanoff, Jeffrey ; Chen, Zhuoliang ; Chen, Ying-Nan P ; Chan, Homan ; Firestone, Brant ; Fodor, Michelle ; Fortanet, Jorge ; Hao, Huaixiang ; Hentemann, Murphy ; Kato, Mitsunori ; Koenig, Robert ; Labonte, Laura R ; Liu, Gang ; Liu, Shumei ; Liu, Chen ; Mcneill, Eric ; Mohseni, Morvarid ; Sendzik, Martin ; Stams, Travis ; Spence, Stan ; Tamez, Victoriano ; Tichkule, Ritesh ; Towler, Christopher S ; Wang, Hongyun ; Wang, Ping ; Williams, Sarah L ; Yu, Bing ; Lamarche, Matthew J

Journal of medicinal chemistry, 28 January 2019 [Peer Reviewed Journal]

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Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity

Mortishire-Smith, Russell J ; Skiles, Gary L ; Lawrence, Jeffrey W ; Spence, Stan ; Nicholls, Andrew W ; Johnson, Bruce A ; Nicholson, Jeremy K

Chemical research in toxicology, February 2004, Vol.17(2), pp.165-73 [Peer Reviewed Journal]

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