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Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation

Fisher, Timothy S ; Lo Surdo, Paola ; Pandit, Shilpa ; Mattu, Marco ; Santoro, Joseph C ; Wisniewski, Doug ; Cummings, Richard T ; Calzetta, Alessandra ; Cubbon, Rose M ; Fischer, Paul A ; Tarachandani, Anil ; De Francesco, Raffaele ; Wright, Samuel D ; Sparrow, Carl P ; Carfi, Andrea ; Sitlani, Ayesha

The Journal of biological chemistry, 13 July 2007, Vol.282(28), pp.20502-12 [Peer Reviewed Journal]

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Structural and biochemical characterization of the wild type PCSK9-EGF(AB) complex and natural familial hypercholesterolemia mutants

Bottomley, Matthew J ; Cirillo, Agostino ; Orsatti, Laura ; Ruggeri, Lionello ; Fisher, Timothy S ; Santoro, Joseph C ; Cummings, Richard T ; Cubbon, Rose M ; Lo Surdo, Paola ; Calzetta, Alessandra ; Noto, Alessia ; Baysarowich, Jennifer ; Mattu, Marco ; Talamo, Fabio ; De Francesco, Raffaele ; Sparrow, Carl P ; Sitlani, Ayesha ; Carfí, Andrea

The Journal of biological chemistry, 09 January 2009, Vol.284(2), pp.1313-23 [Peer Reviewed Journal]

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A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux

Sparrow, Carl P ; Baffic, Joanne ; Lam, My-Hanh ; Lund, Erik G ; Adams, Alan D ; Fu, Xuan ; Hayes, Nancy ; Jones, A Brian ; Macnaul, Karen L ; Ondeyka, John ; Singh, Sheo ; Wang, Jianhua ; Zhou, Gaochao ; Moller, David E ; Wright, Samuel D ; Menke, John G

The Journal of biological chemistry, 22 March 2002, Vol.277(12), pp.10021-7 [Peer Reviewed Journal]

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