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5 Results  for Everything (Includes Articles)

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Novel ATP competitive MK2 inhibitors with potent biochemical and cell-based activity throughout the series

Oubrie, Arthur ; Kaptein, Allard ; de Zwart, Edwin ; Hoogenboom, Niels ; Goorden, Rianne ; van de Kar, Bas ; van Hoek, Maaike ; de Kimpe, Vera ; van Der Heijden, Ruud ; Borsboom, Judith ; Kazemier, Bert ; de Roos, Jeroen ; Scheffers, Michiel ; Lommerse, Jos ; Schultz-Fademrecht, Carsten ; Barf, Tjeerd

Bioorganic & Medicinal Chemistry Letters, 01 January 2012, Vol.22(1), pp.613-618 [Peer Reviewed Journal]

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Discovery of selective and orally available spiro-3-piperidyl ATP-competitive MK2 inhibitors

Kaptein, Allard ; Oubrie, Arthur ; Zwart, Edwin de ; Hoogenboom, Niels ; Wit, Joeri de ; Kar, Bas van de ; Hoek, Maaike van ; Vogel, Gerard ; Kimpe, Vera de ; Schultz-Fademrecht, Carsten ; Borsboom, Judith ; Zeeland, Mario van ; Versteegh, Judith ; Kazemier, Bert ; Roos, Jeroen de ; Wijnands, Frank ; Dulos, John ; Jaeger, Martin ; Leandro-Garcia, Paula ; Barf, Tjeerd

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(12), pp.3823-3827 [Peer Reviewed Journal]

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Structure-based lead identification of ATP-competitive MK2 inhibitors

Barf, Tjeerd ; Kaptein, Allard ; Wilde, Sander de ; Heijden, Ruud van Der ; Someren, Richard van ; Demont, Dennis ; Schultz-Fademrecht, Carsten ; Versteegh, Judith ; Zeeland, Mario van ; Seegers, Nicole ; Kazemier, Bert ; Kar, Bas van de ; Hoek, Maaike van ; Roos, Jeroen de ; Klop, Henri ; Smeets, Ruben ; Hofstra, Claudia ; Hornberg, Jorrit ; Oubrie, Arthur

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(12), pp.3818-3822 [Peer Reviewed Journal]

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6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors

Cai, Jiaqiang ; Baugh, Mark ; Black, Darcey ; Long, Clive ; Jonathan Bennett, D ; Dempster, Maureen ; Fradera, Xavier ; Gillespie, Jonathan ; Andrews, Fiona ; Boucharens, Sylviane ; Bruin, John ; Cameron, Kenneth S ; Cumming, Iain ; Hamilton, William ; Jones, Philip S ; Kaptein, Allard ; Kinghorn, Emma ; Maidment, Maurice ; Martin, Iain ; Mitchell, Ann

Bioorganic & Medicinal Chemistry Letters, 01 August 2010, Vol.20(15), pp.4350-4354 [Peer Reviewed Journal]

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Discovery of quinoline-based irreversible BTK inhibitors

de Bruin, Gerjan ; Demont, Dennis ; de Zwart, Edwin ; Verkaik, Saskia ; Hoogenboom, Niels ; van de Kar, Bas ; van Lith, Bart ; Emmelot- van Hoek, Maaike ; Gulrajani, Michael ; Covey, Todd ; Kaptein, Allard ; Barf, Tjeerd

Bioorganic & Medicinal Chemistry Letters, 15 July 2020, Vol.30(14) [Peer Reviewed Journal]

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