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1 |
Material Type: Article
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Alpha(4)beta(7)/alpha(4)beta(1) dual integrin antagonists block alpha(4)beta(7)-dependent adhesion under shear flowEgger, Linda A ; Kidambi, Usha ; Cao, Jin ; Van Riper, Gail ; Mccauley, Ermengilda ; Mumford, Richard A ; Amo, Suzanne ; Lingham, Russell ; Lanza, Thomas ; Lin, Linus S ; De Laszlo, Stephen E ; Young, David N ; Kopka, Ihor E ; Tong, Sharon ; Pikounis, Bill ; Benson, Evelyn ; Warwood, Sarah ; Bargatze, Robert F ; Hagmann, William K ; Schmidt, John A ; Detmers, Patricia AThe Journal of pharmacology and experimental therapeutics, July 2002, Vol.302(1), pp.153-62 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependenceEgger, Linda A ; Cao, Jin ; Mccallum, Christine ; Kidambi, Usha ; Van Riper, Gail ; Mccauley, Ermengilda ; Mumford, Richard A ; Lanza, Thomas J ; Lin, Linus S ; De Laszlo, Stephen E ; Young, David N ; Yang, Ginger ; Dean, Dennis C ; Raab, Conrad E ; Wallace, Mike A ; Jones, Allen N ; Hagmann, William K ; Schmidt, John A ; Pepinsky, R Blake ; Scott, Daniel M ; Lee, Wen-Cherng ; Cornebise, Mark A ; Detmers, Patricia AThe Journal of pharmacology and experimental therapeutics, September 2003, Vol.306(3), pp.903-13 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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The discovery of small molecule carbamates as potent dual α 4β 1/α 4β 7 integrin antagonistsChang, Linda L ; Truong, Quang ; Mumford, Richard A ; Egger, Linda A ; Kidambi, Usha ; Lyons, Kathryn ; Mccauley, Ermengilda ; Van Riper, Gail ; Vincent, Stella ; Schmidt, John A ; Maccoss, Malcolm ; Hagmann, William KBioorganic & Medicinal Chemistry Letters, 2002, Vol.12(2), pp.159-163 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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Specific and dual antagonists of alpha(4)beta(1) and alpha(4)beta(7) integrinsLin, Linus S ; Lanza, Thomas ; Mccauley, Ermenegilda ; Van Riper, Gail ; Kidambi, Usha ; Cao, Jin ; Egger, Linda A ; Mumford, Richard A ; Schmidt, John A ; Maccoss, Malcolm ; Hagmann, William KBioorganic & medicinal chemistry letters, 21 January 2002, Vol.12(2), pp.133-6 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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N-(3-Phenylsulfonyl-3-piperidinoyl)-phenylalanine derivatives as potent, selective VLA-4 antagonistsGutteridge, Clare E ; de Laszlo, Stephen E ; Kamenecka, Theodore M ; Mccauley, Ermengilda ; van Riper, Gail ; Mumford, Richard A ; Kidambi, Usha ; Egger, Linda A ; Tong, Sharon ; Hagmann, William KBioorganic & Medicinal Chemistry Letters, 2003, Vol.13(5), pp.885-890 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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Amidines as amide bond replacements in VLA-4 antagonistsKamenecka, Theodore M ; Park, You-Jung ; Lin, Linus S ; de Laszlo, Stephen ; Mccauley, Ermengilda D ; Van Riper, Gail ; Egger, Linda ; Kidambi, Usha ; Mumford, Richard A ; Tong, Sharon ; Tang, Wei ; Colletti, Adria ; Teffera, Yohannes ; Stearns, Ralph ; Maccoss, Malcolm ; Schmidt, John A ; Hagmann, William KBioorganic & Medicinal Chemistry Letters, 03 May 2004, Vol.14(9), pp.2323-2326 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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N-Aryl-prolyl-dipeptides as potent antagonists of VLA-4Kamenecka, Theodore M ; Lanza, Jr, Thomas ; de Laszlo, Stephen E ; Li, Bing ; Mccauley, Ermengilda D ; Van Riper, Gail ; Egger, Linda A ; Kidambi, Usha ; Mumford, Richard A ; Tong, Sharon ; Maccoss, Malcolm ; Schmidt, John A ; Hagmann, William KBioorganic & Medicinal Chemistry Letters, 2002, Vol.12(16), pp.2205-2208 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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N-Tetrahydrofuroyl-( l)-phenylalanine derivatives as potent VLA-4 antagonistsYang, Ginger X ; Chang, Linda L ; Truong, Quang ; Doherty, George A ; Magriotis, Plato A ; de Laszlo, Stephen E ; Li, Bing ; Maccoss, Malcolm ; Kidambi, Usha ; Egger, Linda A ; Mccauley, Ermengilda ; Van Riper, Gail ; Mumford, Richard A ; Schmidt, John A ; Hagmann, William KBioorganic & Medicinal Chemistry Letters, 2002, Vol.12(11), pp.1497-1500 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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Substituted tetrahydrofuroyl-1-phenylalanine derivatives as potent and specific VLA-4 antagonistsDoherty, George A ; Yang, Ginger X ; Borges, Edite ; Chang, Linda L ; Maccoss, Malcolm ; Tong, Sharon ; Kidambi, Usha ; Egger, Linda A ; Mccauley, Ermenegilda ; Van Riper, Gail ; Mumford, Richard A ; Schmidt, John A ; Hagmann, William KBioorganic & Medicinal Chemistry Letters, 2002, Vol.12(11), pp.1501-1505 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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Substituted N-(3,5-dichlorobenzenesulfonyl)-L-prolyl-phenylalanine analogues as potent VLA-4 antagonistsKopka, Ihor E ; Young, David N ; Lin, Linus S ; Mumford, Richard A ; Magriotis, Plato A ; Maccoss, Malcolm ; Mills, Sander G ; Van Riper, Gail ; Mccauley, Ermengilda ; Egger, Linda E ; Kidambi, Usha ; Schmidt, John A ; Lyons, Kathryn ; Stearns, Ralph ; Vincent, Stella ; Colletti, Adria ; Wang, Zhen ; Tong, Sharon ; Wang, Junying ; Zheng, Song ; Owens, Karen ; Levorse, Dorothy ; Hagmann, William KBioorganic & medicinal chemistry letters, 25 February 2002, Vol.12(4), pp.637-40 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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Substituted 3-amino biaryl propionic acids as potent VLA-4 antagonistsKopka, Ihor E ; Lin, Linus S ; Mumford, Richard A ; Lanza, Thomas ; Magriotis, Plato A ; Young, David ; Delaszlo, Stephen E ; Maccoss, Malcolm ; Mills, Sander G ; Van Riper, Gail ; Mccauley, Ermengilda ; Lyons, Kathryn ; Vincent, Stella ; Egger, Linda A ; Kidambi, Usha ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Tong, Sharon ; Owens, Karen ; Levorse, Dorothy ; Schmidt, John A ; Hagmann, William KBioorganic & Medicinal Chemistry Letters, 2002, Vol.12(17), pp.2415-2418 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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CorrigendumCorrigendum to “The discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists”[Bioorg. Med. Chem. Lett. 12 (2002) 611]Lin, Linus S ; Kopka, Ihor E ; Mumford, Richard A ; Magriotis, Plato A ; Lanza, Jr, Thomas ; Durette, Philippe L ; Kamenecka, Theodore ; Young, David N ; de Laszlo, Stephen E ; Mccauley, Ermenegilda ; Van Riper, Gail ; Kidambi, Usha ; Egger, Linda A ; Tong, Xinchun ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Fenyk-Melody, Judy ; Schmidt, John A ; Maccoss, Malcolm ; Hagmann, William KBioorganic & Medicinal Chemistry Letters, 2002, Vol.12(12), pp.1695-1695 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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The discovery of sulfonylated dipeptides as Potent VLA-4 antagonistsHagmann, William K ; Durette, Philippe L ; Lanza, Thomas ; Kevin, Nancy Jo ; de Laszlo, Stephen E ; Kopka, Ihor E ; Young, David ; Magriotis, Plato A ; Li, Bing ; Lin, Linus S ; Yang, Ginger ; Kamenecka, Theodore ; Chang, Linda L ; Wilson, Jonathan ; Maccoss, Malcolm ; Mills, Sander G ; Van Riper, Gail ; Mccauley, Ermengilda ; Egger, Linda A ; Kidambi, Usha ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Johannes ; Tong, Sharon ; Fenyk-Melody, Judy ; Owens, Karen ; Levorse, Dorothy ; Kim, Philip ; Schmidt, John A ; Mumford, Richard ABioorganic & Medicinal Chemistry Letters, 2001, Vol.11(20), pp.2709-2713 [Peer Reviewed Journal]Full text available |