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3 Results  for Everything (Includes Articles)

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Discovery of 8-Amino-imidazo[1,5- a ]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis

Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto ; Gao, Xiaolei ; Wang, James ; Boga, Sobhana Babu ; Alhassan, Abdul-Basit ; Yu, Younong ; Vaccaro, Henry ; Liu, Shilan ; Yang, Chundao ; Wu, Hao ; Cooper, Alan ; de Man, Jos ; Kaptein, Allard ; Maloney, Kevin ; Hornak, Viktor ; Gao, Ying-Duo ; Fischmann, Thierry O ; Raaijmakers, Hans ; Vu-Pham, Diep ; Presland, Jeremy ; Mansueto, My ; Xu, Zangwei ; Leccese, Erica ; Zhang-Hoover, Jie ; Knemeyer, Ian ; Garlisi, Charles G ; Bays, Nathan ; Stivers, Peter ; Brandish, Philip E ; Hicks, Alexandra ; Kim, Ronald ; Kozlowski, Joseph A Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

ACS Medicinal Chemistry Letters, 11 February 2016, Vol.7(2) [Peer Reviewed Journal]

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Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like properties

Xiao, Dong ; Zhu, Xiaohong ; Yu, Younong ; Shao, Ning ; Wu, Jie ; Mccormick, Kevin D ; Dhondi, Pawan ; Qin, Jun ; Mazzola, Robert ; Tang, Haiqun ; Rao, Ashwin ; Siliphaivanh, Phieng ; Qiu, Hongchen ; Yang, Xiaoxin ; Rivelli, Maria ; Garlisi, Charles G ; Eckel, Steve ; Mukhopadhyay, Gitali ; Correll, Craig ; Rindgen, Diane

Bioorganic & Medicinal Chemistry Letters, 15 March 2014, Vol.24(6), pp.1615-1620 [Peer Reviewed Journal]

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Use of molecular modeling aided design to dial out hERG liability in adenosine A2A receptor antagonists

Deng, Qiaolin ; Lim, Yeon-Hee ; Anand, Rajan ; Yu, Younong ; Kim, Jae-Hun ; Zhou, Wei ; Zheng, Junying ; Tempest, Paul ; Levorse, Dorothy ; Zhang, Xiaoping ; Greene, Scott ; Mullins, Deborra ; Culberson, Chris ; Sherborne, Brad ; Parker, Eric M ; Stamford, Andrew ; Ali, Amjad

Bioorganic & Medicinal Chemistry Letters, 01 August 2015, Vol.25(15), pp.2958-2962 [Peer Reviewed Journal]

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