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Chemical genetics define the roles of p38alpha and p38beta in acute and chronic inflammation

O'Keefe, Stephen J ; Mudgett, John S ; Cupo, Susan ; Parsons, Janey N ; Chartrain, Nicole A ; Fitzgerald, Catherine ; Chen, Shiow-Ling ; Lowitz, Karen ; Rasa, Cordelia ; Visco, Denise ; Luell, Silvi ; Carballo-Jane, Ester ; Owens, Karen ; Zaller, Dennis M

The Journal of biological chemistry, 30 November 2007, Vol.282(48), pp.34663-71 [Peer Reviewed Journal]

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Discovery of biaryl anthranilides as full agonists for the high affinity niacin receptor

Shen, Hong C ; Ding, Fa-Xiang ; Luell, Silvi ; Forrest, Michael J ; Carballo-Jane, Ester ; Wu, Kenneth K ; Wu, Tsuei-Ju ; Cheng, Kang ; Wilsie, Larissa C ; Krsmanovic, Mihajlo L ; Taggart, Andrew K ; Ren, Ning ; Cai, Tian-Quan ; Deng, Qiaolin ; Chen, Qing ; Wang, Junying ; Wolff, Michael S ; Tong, Xinchun ; Holt, Tom G ; Waters, M Gerard ; Hammond, Milton L ; Tata, James R ; Colletti, Steven L

Journal of medicinal chemistry, 13 December 2007, Vol.50(25), pp.6303-6 [Peer Reviewed Journal]

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Comparison of rat and dog models of vasodilatation and lipolysis for the calculation of a therapeutic index for GPR109A agonists

Carballo-Jane, Ester ; Gerckens, Lynn S ; Luell, Silvi ; Parlapiano, Allison S ; Wolff, Michael ; Colletti, Steven L ; Tata, James R ; Taggart, Andrew K.P ; Waters, M. Gerard ; Richman, Jeremy G ; Mccann, Margaret E ; Forrest, Michael J

Journal of Pharmacological and Toxicological Methods, 2007, Vol.56(3), pp.308-316 [Peer Reviewed Journal]

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Novel glucocorticoids containing a 6,5-bicyclic core fused to a pyrazole ring: Synthesis, in vitro profile, molecular modeling studies, and in vivo experiments

Thompson, Christopher F ; Quraishi, Nazia ; Ali, Amjad ; Mosley, Ralph T ; Tata, James R ; Hammond, Milton L ; Balkovec, James M ; Einstein, Monica ; Ge, Lan ; Harris, Georgianna ; Kelly, Terri M ; Mazur, Paul ; Pandit, Shilpa ; Santoro, Joseph ; Sitlani, Ayesha ; Wang, Chuanlin ; Williamson, Joanne ; Miller, Douglas K ; Yamin, Ting-Ting D ; Thompson, Chris M ; O’neill, Edward A ; Zaller, Dennis ; Forrest, Michael J ; Carballo-Jane, Ester ; Luell, Silvi

Bioorganic & Medicinal Chemistry Letters, 2007, Vol.17(12), pp.3354-3361 [Peer Reviewed Journal]

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Cyclopentane-based human NK1 antagonists. Part 2: Development of potent, orally active, water-soluble derivatives

Meurer, Laura C ; Finke, Paul E ; Owens, Karen A ; Tsou, Nancy N ; Ball, Richard G ; Mills, Sander G ; Maccoss, Malcolm ; Sadowski, Sharon ; Cascieri, Margaret A ; Tsao, Kwei-Lan ; Chicchi, Gary G ; Egger, Linda A ; Luell, Silvi ; Metzger, Joseph M ; Macintyre, D. Euan ; Rupniak, Nadia M.J ; Williams, Angela R ; Hargreaves, Richard J

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(17), pp.4504-4511 [Peer Reviewed Journal]

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