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Results 51 - 83 of 83  for Everything (Includes Articles)

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51
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Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy

Myers, Robert W ; Guan, Hong-Ping ; Ehrhart, Juliann ; Petrov, Aleksandr ; Prahalada, Srinivasa ; Tozzo, Effie ; Yang, Xiaodong ; Kurtz, Marc M ; Trujillo, Maria ; Gonzalez Trotter, Dinko ; Feng, Danqing ; Xu, Shiyao ; Eiermann, George ; Holahan, Marie A ; Rubins, Daniel ; Conarello, Stacey ; Niu, Xiaoda ; Souza, Sandra C ; Miller, Corin ; Liu, Jinqi ; Lu, Ku ; Feng, Wen ; Li, Ying ; Painter, Ronald E ; Milligan, James A ; He, Huaibing ; Liu, Franklin ; Ogawa, Aimie ; Wisniewski, Douglas ; Rohm, Rory J ; Wang, Liyang ; Bunzel, Michelle ; Qian, Ying ; Zhu, Wei ; Wang, Hongwu ; Bennet, Bindu ; Lafranco Scheuch, Lisa ; Fernandez, Guillermo E ; Li, Cai ; Klimas, Michael ; Zhou, Gaochao ; Van Heek, Margaret ; Biftu, Tesfaye ; Weber, Ann ; Kelley, David E ; Thornberry, Nancy ; Erion, Mark D ; Kemp, Daniel M ; Sebhat, Iyassu K

Science (New York, N.Y.), 04 August 2017, Vol.357(6350), pp.507-511 [Peer Reviewed Journal]

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52
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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Nicholson, Donald ; Ali, Ambereen ; Thornberry, Nancy ; Vaillancourt, John

Nature, Jul 6, 1995, pp.37-43 [Peer Reviewed Journal]

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53
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Life and death decisions

Nicholson, Donald ; Thornberry, Nancy

Science, Jan 10, 2003, pp.214-5 [Peer Reviewed Journal]

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54
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Caspases: Killer proteases

Nicholson, Donald ; Thornberry, Nancy

Trends in Biochemical Sciences, Aug 1997, pp.299-306 [Peer Reviewed Journal]

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55
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Apoptosis. Life and death decisions

Nicholson, Donald W ; Thornberry, Nancy A

Science (New York, N.Y.), 10 January 2003, Vol.299(5604), pp.214-5 [Peer Reviewed Journal]

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56
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Review
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Caspases: killer proteases

Nicholson, Donald W ; Thornberry, Nancy A

Trends in Biochemical Sciences, 1997, Vol.22(8), pp.299-306 [Peer Reviewed Journal]

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57
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4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors

Parmee, Emma R ; He, Jiafang ; Mastracchio, Anthony ; Edmondson, Scott D ; Colwell, Larry ; Eiermann, George ; Feeney, William P ; Habulihaz, Bahanu ; He, Huaibing ; Kilburn, Ruth ; Leiting, Barbara ; Lyons, Kathryn ; Marsilio, Frank ; Patel, Reshma A ; Petrov, Aleksandr ; Di Salvo, Jerry ; Wu, Joseph K ; Thornberry, Nancy A ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 2004, Vol.14(1), pp.43-46 [Peer Reviewed Journal]

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58
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Glucagon-Like Peptide 1/Glucagon Receptor Dual Agonism Reverses Obesity in Mice

Pocai, Alessandro ; Carrington, Paul ; Adams, Jennifer ; Wright, Michael ; Eiermann, George ; Zhu, Lan ; Du, Xiaobing ; Petrov, Aleksandr ; Lassman, Michael ; Jiang, Guoqiang ; Liu, Franklin ; Miller, Corey ; Tota, Laurie ; Zhou, Gaochao ; Zhang, Xiaoping ; Sountis, Michael ; Santoprete, Alessia ; Capito, Elena ; Chicchi, Gary ; Thornberry, Nancy ; Bianchi, Elisabetta ; Pessi, Antonello ; Marsh, Donald ; Sinharoy, Ranabir

Diabetes, Oct 2009, pp.2258-66 [Peer Reviewed Journal]

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59
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Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice

Pocai, Alessandro ; Carrington, Paul E ; Adams, Jennifer R ; Wright, Michael ; Eiermann, George ; Zhu, Lan ; Du, Xiaobing ; Petrov, Aleksandr ; Lassman, Michael E ; Jiang, Guoqiang ; Liu, Franklin ; Miller, Corey ; Tota, Laurie M ; Zhou, Gaochao ; Zhang, Xiaoping ; Sountis, Michael M ; Santoprete, Alessia ; Capito', Elena ; Chicchi, Gary G ; Thornberry, Nancy ; Bianchi, Elisabetta ; Pessi, Antonello ; Marsh, Donald J ; Sinharoy, Ranabir

Diabetes, October 2009, Vol.58(10), pp.2258-66 [Peer Reviewed Journal]

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60
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Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets

Ronnebaum, Sarah M ; Jensen, Mette V ; Hohmeier, Hans E ; Burgess, Shawn C ; Zhou, Yun-Ping ; Qian, Su ; Macneil, Douglas ; Howard, Andrew ; Thornberry, Nancy ; Ilkayeva, Olga ; Lu, Danhong ; Sherry, A Dean ; Newgard, Christopher B

The Journal of biological chemistry, 24 October 2008, Vol.283(43), pp.28909-17 [Peer Reviewed Journal]

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61
Kinetic Effects of ATP and Two Cellular Stimulatory Components on Human Leukocyte 5-Lipoxygenase
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Kinetic Effects of ATP and Two Cellular Stimulatory Components on Human Leukocyte 5-Lipoxygenase

Rouzer, Carol A. ; Thornberry, Nancy A. ; Bull, Herbert G.

Annals of the New York Academy of Sciences, 04/1988, Vol.524(1 Biology of th), pp.1-11 [Peer Reviewed Journal]

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62
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Caspase-mediated proteolysis during apoptosis: insights from apoptotic neutrophils

Sanghavi, Darshak M ; Thelen, Marcus ; Thornberry, Nancy A ; Casciola-Rosen, Livia ; Rosen, Antony

FEBS Letters, 1998, Vol.422(2), pp.179-184 [Peer Reviewed Journal]

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63
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Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells

Shang, Jin ; Li, Jing ; Keller, Mark P ; Hohmeier, Hans E ; Wang, Yong ; Feng, Yue ; Zhou, Heather H ; Shen, Xiaolan ; Rabaglia, Mary ; Soni, Mufaddal ; Attie, Alan D ; Newgard, Christopher B ; Thornberry, Nancy A ; Howard, Andrew D ; Zhou, Yun-Ping

Molecular endocrinology (Baltimore, Md.), September 2015, Vol.29(9), pp.1243-53 [Peer Reviewed Journal]

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64
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Downregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion

Soni, Mufaddal S ; Rabaglia, Mary E ; Bhatnagar, Sushant ; Shang, Jin ; Ilkayeva, Olga ; Mynatt, Randall ; Zhou, Yun-Ping ; Schadt, Eric E ; Thornberry, Nancy A ; Muoio, Deborah M ; Keller, Mark P ; Attie, Alan D

Diabetes, November 2014, Vol.63(11), pp.3805-14 [Peer Reviewed Journal]

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65
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Selective Small-Molecule Agonists of G Protein-Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice

Tan, Carina ; Feng, Yue ; Zhou, Yun-Ping ; Eiermann, George ; Petrov, Aleksandr ; Zhou, Changyou ; Lin, Songnian ; Salituro, Gino ; Meinke, Peter ; Mosley, Ralph ; Akiyama, Taro ; Einstein, Monica ; Kumar, Sanjeev ; Berger, Joel ; Mills, Sander ; Thornberry, Nancy ; Yang, Lihu ; Howard, Andrew

Diabetes, Aug 2008, pp.2211-9 [Peer Reviewed Journal]

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66
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Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice

Tan, Carina P ; Feng, Yue ; Zhou, Yun-Ping ; Eiermann, George J ; Petrov, Aleksandr ; Zhou, Changyou ; Lin, Songnian ; Salituro, Gino ; Meinke, Peter ; Mosley, Ralph ; Akiyama, Taro E ; Einstein, Monica ; Kumar, Sanjeev ; Berger, Joel P ; Mills, Sander G ; Thornberry, Nancy A ; Yang, Lihu ; Howard, Andrew D

Diabetes, August 2008, Vol.57(8), pp.2211-9 [Peer Reviewed Journal]

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67
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Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4)

Thornberry, Nancy A ; Gallwitz, Baptist

Best Practice & Research Clinical Endocrinology & Metabolism, 2009, Vol.23(4), pp.479-486 [Peer Reviewed Journal]

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68
Interleukin-1βconverting enzyme: A novel cysteine protease required for IL-1β production and implicated in programmed cell death
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Interleukin-1βconverting enzyme: A novel cysteine protease required for IL-1β production and implicated in programmed cell death

Thornberry, Nancy A. ; Molineaux, Susan M.

Protein Science, 01/1995, Vol.4(1), pp.3-12 [Peer Reviewed Journal]

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69
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Interleukin‐1 β converting enzyme: A novel cysteine protease required for IL‐1 β production and implicated in programmed cell death

Thornberry, Nancy A. ; Molineaux, Susan M.

Protein Science, January 1995, Vol.4(1), pp.3-12 [Peer Reviewed Journal]

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70
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A Novel Heterodimeric Cysteine Protease Is Required for Interleukin-1(Beta) Processing in Monocytes

Thornberry, Nancy ; Bull, Herbert

Nature, Apr 30, 1992, pp.768-74 [Peer Reviewed Journal]

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71
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Caspases: Enemies within

Thornberry, Nancy ; Lazebnik, Yuri

Science, Aug 28, 1998, pp.1312-6 [Peer Reviewed Journal]

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72
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Phosphodiesterase 3 and 4 comprise the major cAMP metabolizing enzymes responsible for insulin secretion in INS-1 (832/13) cells and rat islets

Waddleton, Deena ; Wu, Weizhen ; Feng, Yue ; Thompson, Chris ; Wu, Michael ; Zhou, Yun-Ping ; Howard, Andrew ; Thornberry, Nancy ; Li, Jing ; Mancini, Joseph A

Biochemical Pharmacology, 2008, Vol.76(7), pp.884-893 [Peer Reviewed Journal]

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73
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A model selection approach for expression quantitative trait loci (eQTL) mapping

Wang, Ping ; Dawson, John A ; Keller, Mark P ; Yandell, Brian S ; Thornberry, Nancy A ; Zhang, Bei B ; Wang, I-Ming ; Schadt, Eric E ; Attie, Alan D ; Kendziorski, C

Genetics, February 2011, Vol.187(2), pp.611-21 [Peer Reviewed Journal]

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74
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A Model Selection Approach for Expression Quantitative Trait Loci (eQTL) Mapping

Wang, Ping ; Dawson, John ; Keller, Mark ; Yandell, Brian ; Thornberry, Nancy ; Zhang, Bei ; Wang, I-Ming ; Schadt, Eric ; Attie, Alan ; Kendziorski, C

Genetics, Feb 2011, pp.611-21 [Peer Reviewed Journal]

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75
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Discovery of potent, selective human granzyme B inhibitors that inhibit CTL mediated apoptosis

Willoughby, Christopher A ; Bull, Herbert G ; Garcia-Calvo, Margarita ; Jiang, Joanne ; Chapman, Kevin T ; Thornberry, Nancy A

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(16), pp.2197-2200 [Peer Reviewed Journal]

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76
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Identification of glucose-dependant insulin secretion targets in pancreatic beta cells by combining defined-mechanism compound library screening and siRNA gene silencing

Wu, Weizhen ; Shang, Jin ; Feng, Yue ; Thompson, Chris M ; Horwitz, Sarah ; Thompson, John R ; Macintyre, Euan D ; Thornberry, Nancy A ; Chapman, Kevin ; Zhou, Yun-Ping ; Howard, Andrew D ; Li, Jing

Journal of biomolecular screening, February 2008, Vol.13(2), pp.128-34 [Peer Reviewed Journal]

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77
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Discovery of potent and selective β-homophenylalanine based dipeptidyl peptidase IV inhibitors

Xu, Jinyou ; Ok, Hyun O ; Gonzalez, Edward J ; Colwell, Lawrence F ; Habulihaz, Bahanu ; He, Huaibing ; Leiting, Barbara ; Lyons, Kathryn A ; Marsilio, Frank ; Patel, Reshma A ; Wu, Joseph K ; Thornberry, Nancy A ; Weber, Ann E ; Parmee, Emma R

Bioorganic & Medicinal Chemistry Letters, 2004, Vol.14(18), pp.4759-4762 [Peer Reviewed Journal]

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78
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Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors

Xu, Jinyou ; Wei, Lan ; Mathvink, Robert ; Edmondson, Scott D ; Mastracchio, Anthony ; Eiermann, George J ; He, Huaibing ; Leone, Joseph F ; Leiting, Barbara ; Lyons, Kathryn A ; Marsilio, Frank ; Patel, Reshma A ; Petrov, Aleksandr ; Wu, Joseph K ; Thornberry, Nancy A ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(5), pp.1346-1349 [Peer Reviewed Journal]

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79
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Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors

Xu, Jinyou ; Wei, Lan ; Mathvink, Robert ; He, Jiafang ; Park, You-Jung ; He, Huaibing ; Leiting, Barbara ; Lyons, Kathryn A ; Marsilio, Frank ; Patel, Reshma A ; Wu, Joseph K ; Thornberry, Nancy A ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 16 May 2005, Vol.15(10), pp.2533-2536 [Peer Reviewed Journal]

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80
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Discovery of potent, selective, and orally bioavailable oxadiazole-based dipeptidyl peptidase IV inhibitors

Xu, Jinyou ; Wei, Lan ; Mathvink, Robert J ; Edmondson, Scott D ; Eiermann, George J ; He, Huaibing ; Leone, Joseph F ; Leiting, Barbara ; Lyons, Kathryn A ; Marsilio, Frank ; Patel, Reshma A ; Patel, Sangita B ; Petrov, Aleksandr ; Scapin, Giovanna ; Wu, Joseph K ; Thornberry, Nancy A ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(20), pp.5373-5377 [Peer Reviewed Journal]

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81
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Identification of peptidase substrates in human plasma by FTMS based differential mass spectrometry

Yates, Nathan A ; Deyanova, Ekaterina G ; Geissler, Wayne ; Wiener, Matthew C ; Sachs, Jeffrey R ; Wong, Kenny K ; Thornberry, Nancy A ; Sinha Roy, Ranabir ; Settlage, Robert E ; Hendrickson, Ronald C

International Journal of Mass Spectrometry, 2007, Vol.259(1), pp.174-183 [Peer Reviewed Journal]

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82
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Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists

Zhou, Changyou ; Tang, Cheng ; Chang, Eric ; Ge, Min ; Lin, Songnian ; Cline, Eric ; Tan, Carina P ; Feng, Yue ; Zhou, Yun-Ping ; Eiermann, George J ; Petrov, Aleksandr ; Salituro, Gino ; Meinke, Peter ; Mosley, Ralph ; Akiyama, Taro E ; Einstein, Monica ; Kumar, Sanjeev ; Berger, Joel ; Howard, Andrew D ; Thornberry, Nancy ; Mills, Sander G ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(3), pp.1298-1301 [Peer Reviewed Journal]

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83
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The role of dipeptidyl peptidase IV in the cleavage of glucagon family peptides: in vivo metabolism of pituitary adenylate cyclase activating polypeptide-(1-38)

Zhu, Lan ; Tamvakopoulos, Constantin ; Xie, Dan ; Dragovic, Jasminka ; Shen, Xiaolan ; Fenyk-Melody, Judith E ; Schmidt, Keith ; Bagchi, Ansuman ; Griffin, Patrick R ; Thornberry, Nancy A ; Sinha Roy, Ranabir

The Journal of biological chemistry, 20 June 2003, Vol.278(25), pp.22418-23 [Peer Reviewed Journal]

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