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Potent, brain-penetrant, hydroisoindoline-based human neurokinin-1 receptor antagonists

Jiang, Jinlong ; Bunda, Jaime L ; Doss, Geoge A ; Chicchi, Gary G ; Kurtz, Marc M ; Tsao, Kwei-Lan C ; Tong, Xinchun ; Zheng, Song ; Upthagrove, Alana ; Samuel, Koppara ; Tschirret-Guth, Richard ; Kumar, Sanjeev ; Wheeldon, Alan ; Carlson, Emma J ; Hargreaves, Richard ; Burns, Donald ; Hamill, Terence ; Ryan, Christine ; Krause, Stephen M ; Eng, Waisi ; Devita, Robert J ; Mills, Sander G

Journal of medicinal chemistry, 14 May 2009, Vol.52(9), pp.3039-46 [Peer Reviewed Journal]

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