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Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride:  Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor

Bull, Herbert G. ; Garcia-Calvo, Margarita ; Andersson, Stefan ; Baginsky, Walter F. ; Chan, H. Karen ; Ellsworth, Dina E. ; Miller, Randall R. ; Stearns, Ralph A. ; Bakshi, Raman K. ; Rasmusson, Gary H. ; Tolman, Richard L. ; Myers, Robert W. ; Kozarich, John W. ; Harris, Georgianna S.

Journal of the American Chemical Society, 01/1996, Vol.118(10), pp.2359-2365 [Peer Reviewed Journal]

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