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Fused tricyclic pyrrolizinones that exhibit pseudo-irreversible blockade of the NK 1 receptor

Morriello, Gregori J ; Chicchi, Gary ; Johnson, Tricia ; Mills, Sander G ; Demartino, Julie ; Kurtz, Marc ; Tsao, K.L.C ; Zheng, Song ; Tong, Xinchun ; Carlson, Emma ; Townson, Karen ; Wheeldon, Alan ; Boyce, Susan ; Collinson, Neil ; Rupniak, Nadia ; Devita, Robert J

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(19), pp.5925-5932 [Peer Reviewed Journal]

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