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Substituted fused bicyclic pyrrolizinones as potent, orally bioavailable hNK 1 antagonists

Morriello, Gregori J. ; Mills, Sander G. ; Johnson, Tricia ; Reibarkh, Mikhail ; Chicchi, Gary ; Demartino, Julie ; Kurtz, Marc ; Davies, P. ; Tsao, K.L.C. ; Zheng, Song ; Tong, Xinchun ; Carlson, Emma ; Townson, Karen ; Tattersall, F.D. ; Wheeldon, Alan ; Boyce, Susan ; Collinson, Neil ; Rupniak, Nadia ; Moore, Stephen ; Devita, Robert J.

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(6), pp.2007-2012 [Peer Reviewed Journal]

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