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Do enzymes change the nature of transition states? Mapping the transition state for general acid-base catalysis of a serine protease

Bott, Richard R ; Chan, Gina ; Domingo, Blanca ; Ganshaw, Grant ; Hsia, Constance Y ; Knapp, Mark ; Murray, Christopher J

Biochemistry, 16 September 2003, Vol.42(36), pp.10545-53 [Peer Reviewed Journal]

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