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Discovery of (2 S)- N-[(1 R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-4-methyl-2-piperazinecarboxamide (MB243), a potent and selective melanocortin subtype-4 receptor agonist

Palucki, Brenda L. ; Park, Min K. ; Nargund, Ravi P. ; Ye, Zhixiong ; Sebhat, Iyassu K. ; Pollard, Patrick G. ; Kalyani, Rubana N. ; Tang, Rui ; Macneil, Tanya ; Weinberg, David H. ; Vongs, Aurawan ; Rosenblum, Charles I. ; Doss, George A. ; Miller, Randall R. ; Stearns, Ralph A. ; Peng, Qianping ; Tamvakopoulos, Constantin ; Mcgowan, Erin ; Martin, William J. ; Metzger, Joseph M. ; Shepherd, Cherrie A. ; Strack, Alison M. ; Macintyre, D. Euan ; Van Der Ploeg, Lex H.T. ; Patchett, Arthur A.

Bioorganic & Medicinal Chemistry Letters, 2005, Vol.15(1), pp.171-175 [Peer Reviewed Journal]

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