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Efficient enantioselective synthesis of orthogonally protected ( R)-α-alkylserines compatible with the solid phase peptide synthesis

Vassiliou, Stamatia ; Yiotakis, Athanasios ; Magriotis, Plato A.

Tetrahedron Letters, 2006, Vol.47(41), pp.7339-7341 [Peer Reviewed Journal]

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  • Title:
    Efficient enantioselective synthesis of orthogonally protected ( R)-α-alkylserines compatible with the solid phase peptide synthesis
  • Author: Vassiliou, Stamatia ; Yiotakis, Athanasios ; Magriotis, Plato A.
  • Description: The Schöllkopf methodology for the asymmetric synthesis of α-amino acids, which was previously not applicable to the construction of quaternary α-amino acids, has been rendered not only suitable but also practical for this purpose and applied to a highly efficient enantioselective synthesis of orthogonally protected ( R)-α-alkylserines suitable for the solid phase synthesis.
  • Is Part Of: Tetrahedron Letters, 2006, Vol.47(41), pp.7339-7341
  • Identifier: ISSN: 0040-4039 ; DOI: 10.1016/j.tetlet.2006.08.016
  • Subjects: Α,Α-Disubstituted Α-Amino Acids ; Quaternary Α-Amino Acids ; ( R )-Α-Alkylserines ; Schöllkopf Methodology ; Tert -Buli
  • Language: English
  • Source: ScienceDirect (Elsevier B.V.)

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