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Caspases: Enemies within

Thornberry, Nancy ; Lazebnik, Yuri

Science, Aug 28, 1998, pp.1312-6 [Peer Reviewed Journal]

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  • Title:
    Caspases: Enemies within
  • Author: Thornberry, Nancy ; Lazebnik, Yuri
  • Description: Apoptosis, an evolutionarily conserved form of cell suicide, requires specialized machinery. The central component of this machinery is a proteolytic system involving a family of proteases called caspases. These enzymes participate in a cascade that is triggered in response to proapoptotic signals and...
  • Is Part Of: Science, Aug 28, 1998, pp.1312-6
  • Identifier: ISSN: 00368075 ; E-ISSN: 10959203
  • Subjects: Animals–Chemistry ; Apoptosis–Metabolism ; Catalysis–Metabolism ; Cysteine Endopeptidases–Pharmacology ; Cysteine Endopeptidases–Therapeutic Use ; Cysteine Proteinase Inhibitors–Chemistry ; Cysteine Proteinase Inhibitors–Metabolism ; Cysteine Proteinase Inhibitors–Drug Therapy ; Drug Therapy–Drug Therapy ; Enzyme Activation–Drug Therapy ; Enzyme Precursors–Drug Therapy ; Enzyme Precursors–Drug Therapy ; Humans–Drug Therapy ; Neoplasms–Drug Therapy ; Substrate Specificity–Drug Therapy ; Cells ; Anatomy & Physiology ; Enzymes ; Proteins ; Cysteine Proteinase Inhibitors ; Enzyme Precursors ; Cysteine Endopeptidases
  • Language: English
  • Source: © ProQuest LLC All rights reserved
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