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Perspective: Graduation time

David G. Russell ; Carl F. Nathan

Nature, 2013, Vol.502(7470), p.S7 [Peer Reviewed Journal]

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  • Title:
    Perspective: Graduation time
  • Author: David G. Russell ; Carl F. Nathan
  • Description: The difficulty of finding a new combination is more than additive, as each drug must not interfere with the others or with the antiretrovirals used to treat HIV infection (a common co-infection in sub-Saharan Africa). [...]even if a pharmaceutical company discovers one effective new TB drug (a big if), the chances are that such a drug would be rapidly lost to resistance unless it were used in combination with two or three other new drugs. [...]any such income pales in comparison with the hundreds of millions of dollars that need to be invested to turn lead compounds into drugs.
  • Is Part Of: Nature, 2013, Vol.502(7470), p.S7
  • Identifier: ISSN: 0028-0836 ; E-ISSN: 1476-4687 ; DOI: 10.1038/502S7a
  • Subjects: Pharmaceutical Industry ; Tuberculosis ; Antibiotics ; Drug Resistance ; Infections ; Federal Funding ; Clinical Trials ; Intellectual Property ; Counterfeiting

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