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Structural and biochemical characterization of the wild type PCSK9-EGF(AB) complex and natural familial hypercholesterolemia mutants

Bottomley, Matthew J ; Cirillo, Agostino ; Orsatti, Laura ; Ruggeri, Lionello ; Fisher, Timothy S ; Santoro, Joseph C ; Cummings, Richard T ; Cubbon, Rose M ; Lo Surdo, Paola ; Calzetta, Alessandra ; Noto, Alessia ; Baysarowich, Jennifer ; Mattu, Marco ; Talamo, Fabio ; De Francesco, Raffaele ; Sparrow, Carl P ; Sitlani, Ayesha ; Carfí, Andrea

The Journal of biological chemistry, 09 January 2009, Vol.284(2), pp.1313-23 [Peer Reviewed Journal]

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