skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Index

A simple and convenient two-step, one-pot synthesis of hetero-imidazoles from nitroaminoaryls catalyzed by Ytterbium triflate

Wang, Fen ; Tran-Dubé, Michelle ; Scales, Stephanie ; Johnson, Sarah ; Mcalpine, Indrawan ; Ninkovic, Sacha

Tetrahedron Letters, 31 July 2013, Vol.54(31), pp.4054-4057 [Peer Reviewed Journal]

Full text available

View all versions
Citations Cited by
  • Title:
    A simple and convenient two-step, one-pot synthesis of hetero-imidazoles from nitroaminoaryls catalyzed by Ytterbium triflate
  • Author: Wang, Fen ; Tran-Dubé, Michelle ; Scales, Stephanie ; Johnson, Sarah ; Mcalpine, Indrawan ; Ninkovic, Sacha
  • Description: A mild two-step one-pot procedure for the conversion of -nitroamino aromatic heterocycles into corresponding benzo and heteroaromatic fused imidazoles is described. The procedure utilizes iron powder, acetic acid, triethylorthoformate, and a catalytic amount of Ytterbium triflate at 75 °C for the nitro group reduction and cyclization reaction. The optimum stoichiometry of each component is highlighted and the broad utility is demonstrated with high compatibility to numerous functional groups.
  • Is Part Of: Tetrahedron Letters, 31 July 2013, Vol.54(31), pp.4054-4057
  • Identifier: ISSN: 0040-4039 ; E-ISSN: 1873-3581 ; DOI: 10.1016/j.tetlet.2013.05.092
  • Subjects: One-Pot ; Hetero-Imidazole ; Benzimidazole ; Ytterbium Triflate ; Triethylorthoformate ; Chemistry
  • Language: English

Searching Remote Databases, Please Wait