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Anchored phosphatases modulate glucose homeostasis

Hinke, Simon A ; Navedo, Manuel F ; Ulman, Allison ; Whiting, Jennifer L ; Nygren, Patrick J ; Tian, Geng ; Jiménez Caliani, Antonio Javier ; Langeberg, Lorene K. ; Cirulli, Vincenzo ; Tengholm, Anders ; Dell'Acqua, Mark L ; Santana, L Fernando ; Scott, John D.

EMBO journal: European Molecular Biology Organization, 2012, Issue 20, pp.3991-4004 [Peer Reviewed Journal]

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Title:
Anchored phosphatases modulate glucose homeostasis
Author: Hinke, Simon A ; Navedo, Manuel F ; Ulman, Allison ; Whiting, Jennifer L ; Nygren, Patrick J ; Tian, Geng ; Jiménez Caliani, Antonio Javier ; Langeberg, Lorene K. ; Cirulli, Vincenzo ; Tengholm, Anders ; Dell'Acqua, Mark L ; Santana, L Fernando ; Scott, John D.
Description: AKAP150 knockout- and mutant knock-in alleles reveal an unexpected role of the adaptor in anchoring phosphatase 2B for efficient insulin secretion from pancreatic β-cells and thus glucose homeostasis.
Is Part Of: EMBO journal: European Molecular Biology Organization, 2012, Issue 20, pp.3991-4004
Identifier: ISSN: 0261-4189
Subjects: A - Kinase Anchoring Protein (Akap) ; Calcineurin (Pp2b) ; Cyclic - Amp - Dependent Protein Kinase (Pka) ; Glucoregulation ; Glucose - Stimulated Insulin Secretion (Gsis)
Language: English
Source: Fundación Dialnet

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