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Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain

Chobanian, Harry R. ; Guo, Yan ; Liu, Ping ; Chioda, Marc D. ; Fung, Selena ; Lanza, Thomas J. ; Chang, Linda ; Bakshi, Raman K. ; Dellureficio, James P. ; Hong, Qingmei ; Mclaughlin, Mark ; Belyk, Kevin M. ; Krska, Shane W. ; Makarewicz, Amanda K. ; Martel, Elliot J. ; Leone, Joseph F. ; Frey, Lisa ; Karanam, Bindhu ; Madeira, Maria ; Alvaro, Raul ; Shuman, Joyce ; Salituro, Gino ; Terebetski, Jenna L. ; Jochnowitz, Nina ; Mistry, Shruti ; Mcgowan, Erin ; Hajdu, Richard ; Rosenbach, Mark ; Abbadie, Catherine ; Alexander, Jessica P. ; Shiao, Lin-Lin ; Sullivan, Kathleen M. ; Nargund, Ravi P. ; Wyvratt, Matthew J. ; Lin, Linus S. ; Devita, Robert J.

ACS Medicinal Chemistry Letters, 06/12/2014, Vol.5(6), pp.717-721 [Peer Reviewed Journal]

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Title:
Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain
Author: Chobanian, Harry R. ; Guo, Yan ; Liu, Ping ; Chioda, Marc D. ; Fung, Selena ; Lanza, Thomas J. ; Chang, Linda ; Bakshi, Raman K. ; Dellureficio, James P. ; Hong, Qingmei ; Mclaughlin, Mark ; Belyk, Kevin M. ; Krska, Shane W. ; Makarewicz, Amanda K. ; Martel, Elliot J. ; Leone, Joseph F. ; Frey, Lisa ; Karanam, Bindhu ; Madeira, Maria ; Alvaro, Raul ; Shuman, Joyce ; Salituro, Gino ; Terebetski, Jenna L. ; Jochnowitz, Nina ; Mistry, Shruti ; Mcgowan, Erin ; Hajdu, Richard ; Rosenbach, Mark ; Abbadie, Catherine ; Alexander, Jessica P. ; Shiao, Lin-Lin ; Sullivan, Kathleen M. ; Nargund, Ravi P. ; Wyvratt, Matthew J. ; Lin, Linus S. ; Devita, Robert J.
Is Part Of: ACS Medicinal Chemistry Letters, 06/12/2014, Vol.5(6), pp.717-721
Identifier: ISSN: 1948-5875 ; E-ISSN: 1948-5875 ; DOI: http://dx.doi.org/10.1021/ml5001239
Language: English
Source: American Chemical Society (via CrossRef)

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