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Extrapolation of diclofenac clearance from in vitro microsomal metabolism data: role of acyl glucuronidation and sequential oxidative metabolism of the acyl glucuronide

Kumar, Sanjeev ; Samuel, Koppara ; Subramanian, Ramaswamy ; Braun, Matthew P ; Stearns, Ralph A ; Chiu, Shuet-Hing Lee ; Evans, David C ; Baillie, Thomas A

The Journal of pharmacology and experimental therapeutics, December 2002, Vol.303(3), pp.969-78 [Peer Reviewed Journal]

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