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Discovery of a potent, orally bioavailable pyrimidine VLA-4 antagonist effective in a sheep asthma model

Semko, Christopher M ; Chen, Linda ; Dressen, Darren B ; Dreyer, Mark L ; Dunn, Whitney ; Farouz, Francine S ; Freedman, Stephen B ; Holsztynska, Elizabeth J ; Jefferies, Michael ; Konradi, Andrei W ; Liao, Anna ; Lugar, Judevin ; Mutter, Linda ; Pleiss, Michael A ; Quinn, Kevin P ; Thompson, Thomas ; Thorsett, Eugene D ; Vandevert, Christopher ; Xu, Ying-Zi ; Yednock, Ted A

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(6), pp.1741-1743 [Peer Reviewed Journal]

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